Search

Necrotizing enterocolitis (NEC) is an inflammatory bowel disease that mainly affects low birth weight preterm infants. Because the etiology and pathogenesis of NEC are still incompletely understood, therapeutic options, morbidity and mortality were not significantly improved in the last decade of time. Taking into account the catastrophic development of this disease, it is necessary to focus research on prevention strategies and identify predictive risk factors for its occurrence. Many preventive measures have been tried and accepted in clinical practice, one of these is represented by probiotics supplementation. This article is a review of the literature regarding the efficacy of probiotics as a preventive strategy for NEC in premature infants with low birth weight. [ABSTRACT FROM AUTHOR]

Necrotizing enterocolitis (NEC) is an inflammatory bowel disease that mainly affects low birth weight preterm infants. Because the etiology and pathogenesis of NEC are still incompletely understood, therapeutic options, morbidity and mortality were not significantly improved in the last decade of time. Taking into account the catastrophic development of this disease, it is necessary to focus research on prevention strategies and identify predictive risk factors for its occurrence. Many preventive measures have been tried and accepted in clinical practice, one of these is represented by probiotics supplementation. This article is a review of the literature regarding the efficacy of probiotics as a preventive strategy for NEC in premature infants with low birth weight. [ABSTRACT FROM AUTHOR]

Ventilation associated pneumonia (VAP) is a nosocomial pneumonia occurring after 48 hours of mechanical ventilation. VAP incidence is between 5-40%. We aimed to identify the risk factors associated with VAP in premature infants below 32 weeks gestation and to implement a project to improve medical care. The study was conducted over a period of 20 months in a NICU and included 105 newborns. Diagnostic criteria were clinical, bacteriological and radiological. The incidence of VAP in 2009 was 30% and 23% in 2010. There were 6 deaths in 2009 and 2 deaths in 2010. The need for another intubation was the most important risk factor for VAP. The most common organism isolated in cultures from the endotracheal tube was Klebsiella spp. The new preventive strategies reduced the incidence and morbidity of VAP. Prospective studies are needed to confirm these results. [ABSTRACT FROM AUTHOR]

Ventilation associated pneumonia (VAP) is a nosocomial pneumonia occurring after 48 hours of mechanical ventilation. VAP incidence is between 5-40%. We aimed to identify the risk factors associated with VAP in premature infants below 32 weeks gestation and to implement a project to improve medical care. The study was conducted over a period of 20 months in a NICU and included 105 newborns. Diagnostic criteria were clinical, bacteriological and radiological. The incidence of VAP in 2009 was 30% and 23% in 2010. There were 6 deaths in 2009 and 2 deaths in 2010. The need for another intubation was the most important risk factor for VAP. The most common organism isolated in cultures from the endotracheal tube was Klebsiella spp. The new preventive strategies reduced the incidence and morbidity of VAP. Prospective studies are needed to confirm these results [ABSTRACT FROM AUTHOR]