1. 1-Amino-6-chloro-2-(1H-pyrrol-2-yl)benzimidazole (RS 1350)
- Author
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Romano Silvestri, Mercedes Camalli, Marino Artico, Gabriella De Martino, Augusto Pifferi, and Silvio Massa
- Subjects
Stereochemistry ,General Chemistry ,Dihedral angle ,Condensed Matter Physics ,Ring (chemistry) ,Planarity testing ,Acetic acid ,chemistry.chemical_compound ,chemistry ,Moiety ,Imidazole ,General Materials Science ,Smiles rearrangement ,Pyrrole - Abstract
The title compound (RS 1350), C11H9ClN4, was recently synthesized by a Smiles rearrangement of 1-[(5-chloro-2-nitrophenyl)sulfonyl]-1H-pyrrole-2-carbohydrazide or 1-(5-chloro-2-nitrophenyl)-1H-pyrrole-2-carbohydrazide in powdered iron-glacial acetic acid medium. From the crystallographic analysis, it is observed that, in the title compound, the benzimidazole moiety is planar and forms a dihedral angle of 3.8 (2)° with the pyrrole ring. The near planarity of the two rings indicates an extended conjugation.
- Published
- 2001
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