1. Crystal structure of 4-methoxy-N-(piperidine-1-carbonothioyl)benzamide
- Author
-
Khairi Suhud, Siti Aishah Hasbullah, Musa Ahmad, Lee Yook Heng, and Mohammad B. Kassim
- Subjects
crystal structure ,benzoylthiourea ,piperidine ,pyrrolidine ,benzamide ,anti-cancer ,hydrogen bonding ,C—H...π interactions ,offset π–π interactions ,Crystallography ,QD901-999 - Abstract
In the title compound, C14H18N2O2S, the piperidine ring has a chair conformation. Its mean plane is twisted with respect to the 4-methoxybenzoyl ring, with a dihedral angle of 63.0 (3)°. The central N—C(=S)—N(H)—C(=O) bridge is twisted with an N—C—N—C torsion angle of 74.8 (6)°. In the crystal, molecules are linked by N—H...O and C—H...O hydrogen bonds, forming chains along the c-axis direction. Adjacent chains are linked by C—H...π interactions, forming layers parallel to the ac plane. The layers are linked by offset π–π interactions [intercentroid distance = 3.927 (3) Å], forming a supramolecular three-dimensional structure.
- Published
- 2017
- Full Text
- View/download PDF