1. Chronic mitral regurgitation--significance of the echocardiographic determinants in predicting severity
- Author
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Piotr Pieniazek, Wiesława Tracz, Magdalena Kostkiewicz, Maria Olszowska, and Agata Leśniak-Sobelga
- Subjects
Adult ,medicine.medical_specialty ,Systole ,Heart Ventricles ,Regurgitant volume ,Severity of Illness Index ,Predictive Value of Tests ,Mitral valve ,Internal medicine ,Severity of illness ,Medicine ,Humans ,Heart Atria ,Aged ,Aged, 80 and over ,Mitral regurgitation ,Vena contracta ,business.industry ,Curve analysis ,Mitral Valve Insufficiency ,General Medicine ,Middle Aged ,Myocardial Contraction ,Echocardiography, Doppler, Color ,medicine.anatomical_structure ,ROC Curve ,Predictive value of tests ,Cardiology ,Mitral Valve ,Cardiology and Cardiovascular Medicine ,business ,Blood Flow Velocity ,Follow-Up Studies - Abstract
UNLABELLED The aim of study was to determine the significance of the best echocardiographic parameters for assessing the severity of mitral regurgitation (MR). METHODS The study population consisted of 107 patients, mean age 52 +/- 7 y with chronic isolated non-ischaemic MR. Quantification of the MR was performed using echocardiography through the proximal isovelocity surface area method (regurgitant volume (RV) and the effective regurgitant orifice (ERO) were calculated) and the assessment of vena contracta width (VCW). RESULTS The ROC curve analysis and Peto odds used to differentiate between the significant (III-IV grade) and non-significant (I-II grade) MR groups of patients indicated thatVCW, RV and ERO were the most powerful predictors of MR.The area under the ROC curve was 0.931, 0.944, 0.927, respectively.The cut-off values defining significant MR were: VCW > or =7 mm, RV > or =45 ml, ERO > or = 0.33 cm2. CONCLUSIONS The most powerful predictors of severe MR are VCW, ERO and RV.
- Published
- 2009