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Lichen sclerosus is a chronic immuno-mediated skin disease of the genital region in men and women. The treatment may be pharmacological or surgical, the choice depending on the extension of the involved area, the histological pattern and the level of functional disease complained by the patient. If the biopsy is negative for neoplastic degeneration the treatment may be pharmacological only. In our paper, we describe the case of a patient with vulvar disease and labial fusion, burial of the clitoris and severe introital stenosis. In this case, the treatment was surgical.

Aim: We aim to report the results of the curative, non-palliative, treatment of resection of lung metastases that are secondary to renal cell carcinoma (RCC)., Methods: Between 1988 and 2004, a radical metastasectomy with curative purposes was performed in 20 (11 males and 9 females) patients with renal clear cell carcinoma (RCC) who had already undergone nephrectomy and subsequently metastasectomy of lung metastases. The mean age was 66,9 years (range 48-81 years)., Results: the intraoperative mortality of patients undergoing surgical resection of lung metastases from RCC was 0%; 17 out of 20 patients returned at follow up; 9 patients died; the mean survival-time after nephrectomy was 64+/-42 months (range 7-132 months) and the mean survival-time after metastasectomy was 31+/-29 months (range 4-99 months); 4 out of 9 pts had pulmonary recurrence after surgery. 8 patients are still alive; the mean follow up after nephrectomy was 134+/-115 months (range 30-372 months) and 72+/-44 months (range 25-150 months) after metastasectomy. 1 out of 8 pts had a pulmonary recurrence that was treated by surgery., Conclusions: the radical resection of lung metastases is a safe and effective treatment in selected RCC patients.