A three-impulse point return orbit design method is proposed for the manned lunar high-latitude exploration mission. First, considering the restrictions of the reentry corridor and the landing point simultaneously, the constraint conditions of the point return orbit are analyzed. Second, a serial orbit design strategy is presented. In the initial calculation, by decoupling the three-impulse transfer and the lunar escape, a two-segment patched method based on the pseudo-perilune parameters is proposed to determine the three-impulse point return orbit. The three-impulse transfer segment is backward designed by combining maneuvering at the special points with the Lambert problem in the hybrid orbit model, while the lunar escape segment is forward solved by introducing a comprehensive conic method. In the accurate solution, the result of the initial calculation serves as the initial value to perform the backward and forward integration for two segments in the high-fidelity model, respectively. The simulation examples verify the effectiveness and feasibility of this strategy, and show the advantages of high accuracy of the initial calculation and low velocity increment consumption. Finally, a large amount of simulations are conducted by applying this strategy, and the orbit characteristics are discussed. The research conclusions can provide a reference for the design of the point return orbit scheme for the manned lunar exploration mission. • Two-segment patched method for designing the three-impulse point return orbit. • New three-impulse transfer method with low impulse consumption. • Comprehensive conic method for generating the lunar escape segment. [ABSTRACT FROM AUTHOR]