1. Advances in Approaches to Study Chromatin-Mediated Epigenetic Memory
- Author
-
Yuan Yao, Qing Wen, Tianjun Zhang, Chuanhe Yu, Kui Ming Chan, and Haiyun Gan
- Subjects
Epigenomics ,Histones ,Mammals ,Heterochromatin ,Biomedical Engineering ,Animals ,General Medicine ,Biochemistry, Genetics and Molecular Biology (miscellaneous) ,Protein Processing, Post-Translational ,Chromatin ,Epigenesis, Genetic - Abstract
Chromatin structure contains critical epigenetic information in various forms, such as histone post-translational modifications (PTMs). The deposition of certain histone PTMs can remodel the chromatin structure, resulting in gene expression alteration. The epigenetic information carried by histone PTMs could be inherited by daughter cells to maintain the gene expression status. Recently, studies revealed that several conserved replisome proteins regulate the recycling of parental histones carrying epigenetic information in
- Published
- 2021