1. tREPs─A New Class of Functional tRNA-Encoded Peptides
- Author
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Amrita Chakrabarti, Monika Kaushik, Juveria Khan, Deepanshu Soota, Kalairasan Ponnusamy, Sunil Saini, Siddharth Manvati, Jhalak Singhal, Anand Ranganathan, Soumya Pati, Pawan Kumar Dhar, and Shailja Singh
- Subjects
General Chemical Engineering ,General Chemistry - Abstract
We asked if transfer RNA (tRNA) ever got an opportunity of translating its own sequence during evolution, what would have been the function of such tRNA-encoded peptides (tREPs)? If not, could one artificially synthesize tREPs to study the corresponding functional outcomes? Here, we report a novel, first-in-the-class, chemically synthesized tREP-18 molecule originating from the
- Published
- 2022
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