Search

Your search keyword '"Wang, Jiawen"' showing total 8 results
Start Over Author "Wang, Jiawen" Journal acs applied materials & interfaces
8 results on '"Wang, Jiawen"'

4. Antibiofouling Ultrathin Poly(amidoxime) Membrane for Enhanced U(VI) Recovery from Wastewater and Seawater

Author

Sun, Ye, primary, Liu, Rongrong, additional, Wen, Shunxi, additional, Wang, Jiawen, additional, Chen, Lin, additional, Yan, Bingjie, additional, Peng, Shuyi, additional, Ma, Chao, additional, Cao, Xingyu, additional, Ma, Chunxin, additional, Duan, Gaigai, additional, Wang, Hui, additional, Shi, Se, additional, Yuan, Yihui, additional, and Wang, Ning, additional

Published
2021
Full Text
View/download PDF

8. The Inhibition of SARS-CoV-2 3CL Mproby Graphene and Its Derivatives from Molecular Dynamics Simulations

Author

Wang, Jiawen, Yu, Yi, Leng, Tianle, Li, Youyong, and Lee, Shuit-Tong

Abstract

At present, the most powerful new drugs for COVID-19 are antibody proteins. In addition, there are some star small molecule drugs. However, there are few studies on nanomaterials. Here, we study the intact graphene (IG), defective graphene (DG), and graphene oxide (GO) interacting with COVID-19 protein. We find that they show progressive inhibition of COVID-19 protein. By using molecular dynamics simulations, we study the interactions between SARS-CoV-2 3CL Mproand graphene-related materials (GRMs): IG, DG, and GO. The results show that Mprocan be absorbed onto the surfaces of investigated materials. DG and GO interacted with Mpromore intensely, causing the decisive part of Mproto become more flexible. Further analysis shows that compared to IG and GO, DG can inactivate Mproand inhibit its expression effectively by destroying the active pocket of Mpro. Our work not only provides detailed and reliable theoretical guidance for the application of GRMs in treating with SARS-CoV-2 but also helps in developing new graphene-based anti-COVID-19 materials.

Published
2022
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results