1. Thromboembolic disease: Assessment with whole body MR venography
- Author
-
Silke Bosk, Stefan G. Ruehm, Jörg F. Debatin, S. Massing, Serban Mteiescu, and Knut Kroeger
- Subjects
First pass ,medicine.medical_specialty ,Interventional magnetic resonance imaging ,Human organism ,business.industry ,Normal component ,Signal ,medicine ,Radiology, Nuclear Medicine and imaging ,Thromboembolic disease ,Radiology ,Mr venography ,business ,Whole body - Abstract
CONCLUSION: During passage of CO2, the signal loss on MRI images resulted from the temporary replacement of the protons by CO2, which appeared to show an extremely low signal. Therefore CO2 was quite distinctive from other contrast agents that mostly depend on T1 shortening caused by a paramagnetic agent. Since CO2 is a normal component in the blood, the human organism is equipped to clear large quantities of CO2 completely during the first pass through the lungs. The combination of CO2 , resulting in signal loss, and a bloodpool agent, resulting in high signal, is a, new, safe promising method for guidance of a catheter-tip during interventional MRI. Like in fluoroscopy-guided vascular interventions it will enable real time evaluation of flow and inadvertently occurring subtle changes, like small dissections.
- Published
- 2005
- Full Text
- View/download PDF