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Objectives Of the 1.1 million people in the United States infected with human immunodeficiency virus (HIV), more than 20% are unaware of their infection. To increase early diagnosis and treatment, New York State recently passed legislation mandating that HIV testing be offered to all patients, ages 13 to 64 years, receiving health care services. Implementation of this legislation is complex, especially in the emergency department (ED). This study explores ED providers' perceptions of the factors affecting the implementation of the law. Methods The authors conducted six focus group sessions and three in-depth interviews with ED health care providers from two New York City teaching hospitals. Sessions were audiotaped and transcribed. Data were coded and summarized thematically through an iterative process after each session. Results A total of 49 providers participated and data saturation was achieved. Six factors were identified that predispose a provider to offer an HIV test: 1) self-efficacy, 2) behavioral intention, 3) the testing process, 4) provider knowledge of the legislation, 5) type of HIV test, and 6) follow-up procedures. Five factors were identified that enable providers to offer an HIV test: 1) resources related to time, 2) space, 3) staff, 4) type of test, and 5) timing of the offer. Improving access to HIV testing, linkage to care, and public health were all key factors in reinforcing providers' desire to offer HIV tests. Concerns regarding overall cost saving and coverage for the test were indicated as barriers that needed to be resolved to reinforce the providers to offer an HIV test. Conclusions Understanding the factors influencing the practice of ED providers charged with carrying out this mandate is critical. Despite earlier research that indicated that offering HIV testing to ED patients is largely influenced by cost, this study found additional factors that are important to consider to effectively implementing HIV testing in the ED. Resumen Percepciones de los Sanitarios sobre los Factores que Influyen en la Aplicacion de la Ley Obligatoria del Test de VIH en el Estado de Nueva York en Dos Servicios de Urgencias Universitarios Urbanos Objetivos De los 1,1 millones de personas infectadas en Estados Unidos por el virus de la inmunodeficiencia humana (VIH), mas del 20% desconoce su infeccion. Para incrementar el diagnostico y el tratamiento precoz, el estado de Nueva York aprobo recientemente una ley obligatoria segun la cual el test de VIH se ofrecera a todos los pacientes, entre 13 y 64 anos, que reciban atencion sanitaria. La aplicacion de esta ley es compleja, especialmente en el servicio de urgencias (SU). Este estudio explora las percepciones de los sanitarios de urgencias sobre los factores que afectan a la aplicacion de esta ley. Metodologia Se llevaron a cabo seis sesiones de grupo y tres entrevistas en profundidad con sanitarios del SU de dos hospitales universitarios en la ciudad de Nueva York. Las sesiones fueron grabadas en casete y trascritas. Los datos se codificaron y resumieron tematicamente a traves de un proceso iterativo tras cada sesion. Resultados Un total de 49 sanitarios participaron y se alcanzo la saturacion de los datos. Se identificaron seis factores que predisponian a un sanitario a ofrecer un test de VIH: 1) la autoeficacia, 2) la intencion del comportamiento, 3) el proceso diagnostico, 4) el conocimiento de la ley por el sanitario, 5) el tipo de test de VIH, y 6) el seguimiento de los procedimientos. Se identificaron cinco factores que permitirian a los sanitarios ofertar un test de VIH: 1) los recursos relacionados con el tiempo, 2) el espacio, 3) el personal, 4) el tipo de test, y 5) el tiempo de la oferta. A la hora de reforzar el deseo de los sanitarios a ofertar un test de VIH, la mejora al acceso al test de VIH, vinculado a la atencion, y la salud publica fueron todos ellos factores clave. El ahorro de costes totales y la cobertura del test se senalaron como barreras que son necesarias resolver con el fin de reforzar a los sanitarios a ofertar un diagnostico de VIH. Conclusiones El conocimiento de los factores que influyen en la practica de los sanitarios del SU junto con la aplicacion de este mandato es crucial. A pesar de la investigacion mas reciente que indica que ofrecer un test de VIH a los pacientes del SU esta claramente influida por los costes, este estudio encontro factores adicionales que son importantes considerar para aplicar efectivamente el test de VIH en el SU.

Objectives: The authors sought to identify predictors of intensive care unit (ICU) admission among children hospitalized with bronchiolitis for ≥24 hours. Methods: The authors conducted a prospective cohort study during two consecutive bronchiolitis seasons, 2004 through 2006, in 30 U.S. emergency departments (EDs). All included patients were aged

Background: Multicenter studies are becoming more common, and variability in local institutional review board (IRB) assessments can be problematic. Objective: To investigate the variability of IRB responses to a multicenter observational study of children presenting to emergency departments. Methods: The authors collected the original IRB applications, subsequent correspondence, and a survey assessing submission timing and response and the nature of IRB queries. The study was conducted as part of the Emergency Medicine Network http://www.emnet-usa.org Results: Of 37 sites initiating the IRB process, 34 (92%) participated in this IRB-approved study. Institutional review boards returned initial applications in a median of 19 days (IQR, 11–34 d), and 91% considered the protocol to be minimal risk. Of 34 submissions, 13 required no changes, 18 received conditional approvals, and 3 were deferred. The median time from initial submission to final approval was 42 days (IQR, 27–61 d). Seven sites did not participate in patient recruitment: two had institutional issues, one obtained IRB approval too late for participation, and four sites (12%) reported that IRB hurdles contributed to their lack of participation. Nonetheless, 68% of sites that recruited patients reported that the overall experience made them more likely to participate in future multicenter research. Conclusions: There was substantial variation in IRB assessment of a standard protocol in this study. The burden of the application process contributed to some investigators not participating, but the majority of investigators remain enthusiastic about multicenter research. A national IRB may streamline the review process and facilitate multicenter clinical research.

Background: Emergency department (ED) visit volumes are increasing nationwide. Objectives: To determine whether states with primary care shortages have higher rates of ED use. Methods: Populations residing in primary care shortage areas were abstracted from the Health Resources and Services Administration Geospatial Database. Annual ED visit volumes were available from the 2001 National ED Inventory. Population data and potential confounders were abstracted from federal data sets. All analyses were conducted at the state level. Results: Primary care shortage densities varied greatly across states, ranging from 3 (New Jersey) to 28 (Mississippi) medically underserved individuals per 100 people. States also varied in their annual ED visit densities, ranging from 23 visits (Hawaii) to 65 visits (Washington, DC) per 100 people. Of the 17 states in the top tertile for primary care shortage, 7 also were in the top tertile for ED visits. Primary care shortage density was positively associated with ED visit density. An increase of 10 medically underserved individuals per 100 people was associated with an annual increase of 4.2 ED visits per 100 people (p = 0.04). The association remained after controlling for six factors, with an increase of 10 medically underserved individuals per 100 people associated with an annual increase of 3.3 ED visits per 100 people (p = 0.04). Nevertheless, five states had high ED visit densities despite comparatively low primary care shortage densities (Maine, Massachusetts, New Hampshire, Rhode Island, and Vermont), whereas five others had low ED visit densities despite high primary care shortage densities (Arizona, Idaho, Montana, New Mexico, and South Dakota). Conclusions: A positive association between primary care shortage densities and ED visit densities was found. Although most states adhere to this pattern, some states do not. Further investigation of this dissociation may yield additional explanations for rising ED visit volumes.

Objectives To determine the patient factors associated with hospital admission among adults who present to the emergency department (ED) with acute exacerbations of chronic obstructive pulmonary disease (COPD) and to determine whether admissions were concordant with recommendations in the Global Initiative for Chronic Obstructive Lung Disease (GOLD) guidelines. Methods The authors performed a prospective multicenter cohort study involving 29 EDs in the United States and Canada. By using a standard protocol, consecutive ED patients with COPD exacerbation were interviewed, and their charts were reviewed. Predictors of admission were determined by multivariate logistic regression. Results Of 384 patients, 233 (61%; 95% confidence interval = 56% to 66%) were admitted. Multivariate analysis showed that a higher likelihood of admission was associated with older age, female gender, more pack-years of smoking, recent use of inhaled corticosteroid, self-reported activity limitation in the past 24 hours, higher respiratory rate at ED presentation, and a concomitant diagnosis of pneumonia. Patients who reported the ED as their usual site for problem COPD care, or who had mixed COPD and asthma, were less likely to be admitted. The authors confirmed five of the seven testable indications for hospital admission in the GOLD guidelines. Conclusions Several patient factors were independently associated with hospital admission among ED patients with COPD exacerbations. Overall, concordance with admission recommendations in the GOLD guidelines was high. The authors also identified a few novel predictors of admission (female gender, ED as the usual site for problem COPD care, mixed diagnosis of COPD and asthma, recent use of inhaled corticosteroid) that require replication in future studies.

Objectives: Although more men are diagnosed as having chronic obstructive pulmonary disease (COPD), its prevalence is increasing among women. Little is known about gender differences in exacerbations of COPD. The objective of this study was to determine if acute presentation, management, and outcomes differ among men and women seeking care in the emergency department (ED) for exacerbation of COPD. Methods: This was a secondary analysis of a prospective cohort study of ED patients aged 55 years or older who presented with an exacerbation of COPD. Subjects underwent structured interviews in the ED and two weeks later. Results: The cohort consisted of 397 subjects with COPD, of whom 52% were women. Self-report of COPD only tended to be more common among men (61% of men vs. 52% of women), while mixed COPD/asthma tended to be more common among women (39% vs. 48%; p = 0.10). Despite reporting similar chronic symptom severity, women were less likely than men to use anticholinergic agents before their ED visit (59% vs. 69%; p = 0.04). During the exacerbation, women initiated less home therapy and were less likely to seek emergency care within the first 24 hours of symptom onset (25% vs. 36%; p = 0.01). Although ED care and disposition were similar, post-ED outcomes differed. At two-week follow-up, men were more likely to report an ongoing exacerbation (42% vs. 31%; p = 0.03). Conclusions: Men and women who present to the ED for treatment of an exacerbation of COPD have substantial differences in long-term medication use, self-treatment during exacerbation, delay in emergency care, and post-ED outcomes. Further studies are warranted to confirm and explain these gender-related differences.

Objectives: To demonstrate the problem of ‘‘confounding by severity’’ using the example of intravenous (IV) versus oral corticosteroids for the treatment of acute asthma. Double-blind, randomized trials have clearly demonstrated that IV and oral corticosteroids have comparable efficacy. Methods: Using a standardized protocol, 64 emergency departments enrolled 1,847 patients, aged 18–54 years, with acute asthma. Because route of corticosteroid therapy was not randomized, potential confounders of the association between corticosteroid route and hospital admission were controlled for by multivariate logistic regression and stratification. Results: Among the 1,193 patients, 383 (32%) received IV corticosteroids and 810 (68%) received oral corticosteroids. The two groups differed markedly at baseline, with patients receiving IV corticosteroids having more severe asthma. Overall, patients receiving IV corticosteroids were more likely to be admitted or experience a relapse event within 48 hours (51% vs. 19%; p , 0.001). On multivariate analysis, patients receiving IV corticosteroids remained more likely to be admitted or experience a relapse event within 48 hours (odds ratio = 2.6; 95% confidence interval = 1.2 to 6.0). Conclusions: In this observational study, patients with worse asthma exacerbations were more likely to receive IV corticosteroids as compared with oral corticosteroids. Although we controlled for many markers of asthma severity, we were unable to completely control for baseline differences between the IV and oral corticosteroid groups. Observational research continues to serve as an important tool for describing problems and for understanding many exposure–disease associations. For examining the impact of treatments on adverse outcomes, randomized trials are often required to avoid intractable confounding by severity. Key words: asthma; corticosteroids; confounding by severity. ACADEMIC EMERGENCY MEDICINE 2005; 12:439–445.

Objectives To estimate the prevalence of complementary and alternative medicine (CAM) usage among emergency department (ED) patients. Methods This study was a cross-sectional study in four Boston-area EDs. For two 24-hour periods, the authors interviewed consecutive patients age 18 and older about whether they had ever used or had recently (within the past year) used CAM "remedies" (e.g., herbal treatments) or "therapies" (e.g., chiropractic). The authors also asked about the patient's disclosure of CAM usage to allopathic health care providers. Results Of 978 patients, 752 patients were eligible. Among these, 539 (72%) were interviewed. Of these patients, ever having used CAM was reported by 57% (95% CI = 52% to 61%), and 37% (95% CI = 33% to 41%) reported use in the past year. In a multivariate model of recent CAM usage, independent predictors were younger age, higher education level, and chronic pain. Patients who spoke Spanish as their primary language were less likely to report CAM usage. Disclosure of CAM usage to allopathic providers was low, yet >80% reported that they would be comfortable discussing their CAM usage with allopathic providers. Conclusions CAM usage was common among ED patients enrolled in our study, despite underreporting to ED staff. Given the growing evidence of benefits and hazards from popular CAM remedies and therapies, ED staff should consider raising this health issue with their patients.

Objectives The authors sought to determine the 12-month prevalence of depression among emergency department (ED) patients using a single-question screen. Methods This cross-sectional study was conducted in four Boston-area EDs. For two 24-hour periods, consecutive patients aged 18 years or older were interviewed, excluding those who were severely ill, potential victims of sexual assault, or emotionally disturbed. During the interview, patients were asked "Have you had any of the following problems during the past 12 months?" Patients answered "yes" or "no" to a list of health problems that included depression. In a validation study, the authors found that this simple approach correlated well with results from the validated Center for Epidemiologic Studies Depression Scale. Results Of 752 eligible patients, 539 (72%) were interviewed. Of these patients, 30% (95% confidence interval = 26% to 34%) reported depression within the past 12 months. Compared with their nondepressed counterparts, depressed patients were more likely middle-aged, female, and of lower socioeconomic status. Depressed patients were more likely to be smokers and to report a diagnosis of asthma or arthritis/rheumatism. In a multivariate analysis, factors that were independently associated with depression were lower level of education, smoking, and self-reported anxiety, chronic fatigue, and back problems. Conclusions A 30% 12-month prevalence of depression among ED patients was found. Depressed patients had a distinct sociodemographic and health profile. In the future, awareness of risk factors for depression in the ED setting and use of simple screening instruments could aid in the recognition of depression, with subsequent referral to mental health services.