1. Biliary complications after orthotopic liver transplantation: MRCP findings
- Author
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Giuseppe Como, Rossano Girometti, Lorenzo Cereser, Chiara Zuiani, and Massimo Bazzocchi
- Subjects
medicine.medical_specialty ,Cholangiopancreatography, Magnetic Resonance ,Biliary Tract Diseases ,Urology ,medicine.medical_treatment ,Liver transplantation ,Gastroenterology ,Liver disease ,Postoperative Complications ,Cholangiography ,Risk Factors ,Internal medicine ,medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,Radiological and Ultrasound Technology ,Common bile duct ,medicine.diagnostic_test ,Bile duct ,business.industry ,General Medicine ,Hepatology ,medicine.disease ,Liver Transplantation ,Transplantation ,medicine.anatomical_structure ,Biliary tract ,Radiology ,business - Abstract
Orthotopic liver transplantation is a widely accepted treatment for end-stage liver disease and selected cases of hepatocellular carcinoma. Despite surgical progresses, biliary complications after transplantation remain a serious cause of morbidity, mortality, and graft dysfunction or failure in recipients. Early complications occur within a few weeks after transplantation and are mainly represented by bile leakage. Late complications, which become evident from 3 months to years, include strictures, stones, intraductal debris or sludge formation, kinking and ampullary dysfunction. Donor-to-recipient common bile duct disproportion has been reported as a borderline condition. Diagnosis is challenging because of the low specificity of clinical and biologic findings. Sonography does not provide projectional images of the biliary tract or direct evaluation of the anastomoses. Moreover, direct cholangiographic procedures have an unacceptable rate of complications to be used in patients with low clinical suspicion. Magnetic resonance cholangiography is a safe and accurate tool, playing an increasing role in the diagnosis and management of biliary complications. Heavily T2-weighted images provide panoramic, detailed evaluation of the biliary tract, showing biliary complications as a variable combination of bile duct dilatation, strictures, filling defects, fluid collections and peculiar morphologic changes, as described in this paper.
- Published
- 2007
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