1. Desmopressin Reverses Overly Rapid Serum Sodium Correction in a Hyponatremic Patient Undergoing Living Donor Liver Transplantation
- Author
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Jane S. Yu, Erika L. Brinson, Michael P. Bokoch, and Linda L. Liu
- Subjects
medicine.medical_specialty ,Sodium ,medicine.medical_treatment ,Chronic Liver Disease and Cirrhosis ,Urology ,chemistry.chemical_element ,Liver transplantation ,Oral and gastrointestinal ,Hemostatics ,End Stage Liver Disease ,03 medical and health sciences ,Liver disease ,0302 clinical medicine ,Clinical Research ,Risk Factors ,030202 anesthesiology ,Living Donors ,Humans ,Medicine ,Deamino Arginine Vasopressin ,Desmopressin ,Transplantation ,Intraoperative Care ,business.industry ,Liver Disease ,General Medicine ,Perioperative ,medicine.disease ,Liver Transplantation ,chemistry ,030211 gastroenterology & hepatology ,Digestive Diseases ,business ,Hyponatremia ,Living donor liver transplantation ,medicine.drug - Abstract
Patients with end-stage liver disease are often hyponatremic due to multiple physiological processes associated with hepatic failure. For severely hyponatremic patients undergoing liver transplantation, intraoperative management of serum sodium concentration ([Na]s) is challenging. [Na]s tends to increase during transplantation by the administration of fluids with higher sodium concentration than the patient's [Na]s. An overly rapid increase in [Na]s (>1 mEq·L·hour) is difficult to avoid and increases the risk of serious perioperative complications. We report the successful use of intravenous desmopressin to reverse an overly rapid rise in [Na]s during living donor liver transplantation.
- Published
- 2018
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