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Background: Cardiac-MRI of the pressure overloaded right ventricle(RV) of precapillary pulmonary hypertension(PH) patients, exhibits Late Gadolinium Enhancement at the interventricular insertion regions. Native T1-mapping is an new technique to quantify myocardium without the need of a reference area of the myocardium and without requiring the use of contrast agents. Aim: To characterize the myocardium of precapillary PH patients using native T1-mapping, to see whether native T1-values(T1 native ) were related to disease severity and to compare T1 native between the different precapillary PH categories. Methods: Native T1-mapping was acquired on a 1.5T scanner in 46 idiopathic pulmonary arterial hypertension(IPAH) patients, 14 systemic scleroderma related PH(PAH-SSc) patients and 10 chronic thromboembolic PH(CTEPH) patients on a mid-ventricular short axis imaging plane. T1 native were assessed using regions of interest at the RV free wall, LV free wall, interventricular septum and interventricular insertion regions. Results: T1 native of the interventricular insertion regions were significantly higher than the T1 native of the RV free wall, LV free wall and interventricular septum. T1 native were not different between IPAH, PAH-Ssc and CTEPH patients. T1 native at the insertion regions were significantly related to right atrial pressure, RV end-diastolic volume index, RVEF and NT pro-BNP levels. Conclusions: T1 native of the interventricular insertion regions are significantly increased in precapillary PH and related to disease severity. Native T1-mapping can be an alternative technique to characterize the interventricular insertion regions and has the advantage of not requiring the use of contrast agents.