1. Ultrasound Generation Enhancement with Carbon-Based Nanoparticles as Photoacoustic Sensitizers
- Author
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Boris Zousman, Olga Levinson, A. G. Kuzmich, Vladimir Lysenko, Mykola Isaiev, K. Dubyk, Aleksey Rozhin, and Sergei Alekseev
- Subjects
Materials science ,Biocompatibility ,business.industry ,Graphene ,Ultrasound ,Oxide ,Nanoparticle ,02 engineering and technology ,010402 general chemistry ,021001 nanoscience & nanotechnology ,Laser ,01 natural sciences ,Imaging phantom ,0104 chemical sciences ,law.invention ,Nanomaterials ,chemistry.chemical_compound ,chemistry ,law ,Optoelectronics ,0210 nano-technology ,business - Abstract
Laser ultrasound enhancement with carbon-based nanomaterials incorporated into phantom tissues is reported. More specifically, impact of nanodiamonds and graphene oxide on the efficiency of photoinduced pressure excitation was investigated. Agarose-based phantom tissues with and without the nanoparticles were compared. The second harmonic of pulsed Nd:Yag laser (532 nm) was chosen for ultrasound generation. Specific acoustic probe was fabricated for laser-induced ultrasound registration. Dependence of the ultrasound amplitude on concentration of the nanoparticles incorporated into the phantom tissues was analyzed in details. The most significant enhancement of the amplitude ensured by graphene oxide was stated. Considering biocompatibility of the both types of carbon-based nanomaterials, they can be potentially used in future as contrast agents for bio-imaging and theranostic applications.
- Published
- 2018
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