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Cardiovascular disease is the number one cause of death today in developed countries and is projected to remain so. Cardiac intervention is a minimally invasive solution to diagnose and treat the disease. Training of young cardiologists is playing an important role towards quality cardiac healthcare. The advance of interactive and graphics technologies has offered a new avenue to train young cardiologists using virtual patients which can tremendously reduce the cost and risk. This paper presents a novel interactive simulation for cardiac intervention. Two-body collision between the catheter and the heart wall is detected based on a boundary representation. GPU based algorithms are developed to enhance the performance of simulator for real-time and realistic cardiac intervention.