1. H1N1pdm09 is an independent risk factor for severe influenza
- Author
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Francisco De Pablo, Jose Javier Vengoechea, Elisa Mincholé, Carolina Panadero, Ana Lucía Figueredo Cacacho, Dinora Polanco, Laura Royo, and Salvador Bello Dronda
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0301 basic medicine ,medicine.medical_specialty ,ARDS ,Oseltamivir ,Septic shock ,business.industry ,viruses ,030106 microbiology ,virus diseases ,Retrospective cohort study ,medicine.disease ,Intensive care unit ,respiratory tract diseases ,law.invention ,03 medical and health sciences ,Pneumonia ,chemistry.chemical_compound ,chemistry ,law ,Internal medicine ,medicine ,Coinfection ,Risk factor ,Intensive care medicine ,business - Abstract
INTRODUCTION: Since 2009, influenza A H1N1pdm09 coexists with seasonal influenza (H3N2). The aim of this study was to describe the severity differences between both. METHODS: A retrospective study from January to March 2014 in Hospital Miguel Servet, Zaragoza, Spain. We studied hospitalized adults with influenza A, and compared radiologic, clinical manifestations and outcomes. Multivariable analysis was performed for severity, defined as the presence of bilateral or multilobar pneumonia, septic shock, intensive care unit (ICU) admission, acute respiratory distress syndrome (ARDS) and intrahospitalary mortality. RESULTS: Out of 234 patients, 146 had A-H1N1 and 88 A-H3N2, and everyone received Oseltamivir within 24 h from admittance. The median age was 64 years old in H1N1 and 77 in H3N2 (P
- Published
- 2016
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