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The problem of choosing an effective etiotropic treatment for acute respiratory viral infections in young children is one of the urgent in pediatrics.Materials and methods. The article presents data on the mechanism of the combined antiviral and immunomodulating action of the drug recombinant interferon alpha-2b. The results of observation of 80 children aged 3 to 12 months with acute respiratory viral infections of various etiologies are presented. Results. Clinical and laboratory indicators of intoxication that occur during acute respiratory viral infections in children have been identified. It has been shown that the use of rectal suppositories of interferon alpha-2b in the treatment of young children with acute respiratory viral infections causes a rapid relief of the clinical symptoms of the disease and helps to reduce the duration of hospital treatment of patients.

Infants are dominated among patients with respiratory syncytial viral infection (RSVI). In patients with RSVI characteristic are lesions of the lower respiratory tract and development of bronchial obstruction. Laboratory indicators of intoxication (the level of CRP, Leukocyte index of intoxication (LII), hematologic indicator of intoxication (GPI), metabolic disorders and decreased oxygen saturation below 93% are indicators of the severity of the disease, which can predict the development of a more severe course of RSVI and its complications.