1. ‘Granulomatosis with polyangiitis after Pfizer vaccination’: a case report
- Author
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Essien, Francis, Evans, Jordan, Kyle, Andrew, Urisman, Anatoly, and Adams, Nicholas
- Subjects
Medical Microbiology ,Biomedical and Clinical Sciences ,Emerging Infectious Diseases ,Orphan Drug ,Vaccine Related ,Rare Diseases ,Immunization ,Prevention ,3.4 Vaccines ,Prevention of disease and conditions ,and promotion of well-being ,Infection ,Good Health and Well Being ,ANCA vasculitis ,COVID-19 Pfizer vaccine ,granulomatous with polyangiitis ,hemoptysis ,pauci-immune glomerulonephritis - Abstract
The advent of COVID-19, caused by the SARS-CoV-2 virus, has resulted in over 541 million cases with 6.32 million deaths worldwide as of June 2022. The devastating consequences of this global pandemic resulted in the expedited generation of mRNA-based vaccines such as the Pfizer-BioNTech and Moderna vaccines. Although the vaccines have been effective, with recent data indicating greater than 95% effectiveness, rare complications have been reported, including manifestations of autoimmune phenomena. Herein, we report a rare case of Granulomatosis with polyangiitis (GPA) in an active duty military male soon after receiving the first dose of the Pfizer-BioNTech COVID-19 vaccine.
- Published
- 2022