1. Prognostic Factors to Determine Survivorship of Meniscal Allograft Transplant: A Systematic Review.
- Author
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Wang, Ding-Yu, Lee, Cassandra A, Li, Yan-Zhang, Zhang, Bo, Li, Nan, Jiang, Dong, and Yu, Jia-Kuo
- Subjects
ACL ,cartilage ,meniscal allograft transplant ,osteotomy ,prognostic factor ,survivorship ,Prevention ,Transplantation ,Clinical Research ,Clinical Sciences ,Human Movement and Sports Sciences - Abstract
BackgroundThere is much room for improvement and optimization of meniscal allograft survivorship.PurposeTo understand prognostic factors for survivorship using evidence-based selection criteria in order to identify patients who would best benefit from meniscal allograft transplant (MAT).Study designSystematic review; Level of evidence, 4.MethodsWe conducted this systematic review to analyze prognostic factors for survivorship of MAT. The Cochrane Central Register, PubMed publisher, Embase.com, and Web of Science databases were searched through August 8, 2019. Included studies entailed patients of any age who received MAT with a reported association between prognostic factors and survivorship of the allograft. Two reviewers independently screened all titles and abstracts for eligibility, extracted the data, assessed the risk of bias using the Newcastle-Ottawa Scale, and performed a best-evidence synthesis.ResultsThe review included 18 studies with a total of 1920 patients. The mean follow-up time was 6.0 years (range, 2.1-11.2 years). A total of 20 prognostic factors were identified and shown to be associated with survivorship of MAT. Strong evidence was found that severe cartilage damage was associated with poor survivorship. Strong evidence was also found showing that sex, knee compartment, surgical side, concomitant anterior cruciate ligament (ACL) reconstruction, and concomitant osteotomy for malalignment had no effect on survivorship. Moderate evidence was found that body mass index (
- Published
- 2021