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1. TREM2 in neurodegeneration: Evidence for association of the p.R47H variant with frontotemporal dementia and Parkinson's disease

Author

Miller, Bruce, Rayaprolu, S, Mullen, B, Baker, M, Lynch, T, Finger, E, Seeley, WW, Hatanpaa, KJ, Lomen-Hoerth, C, Kertesz, A, and Bigio, EH

Abstract

Background: A rare variant in the Triggering Receptor Expressed on Myeloid cells 2 (TREM2) gene has been reported to be a genetic risk factor for Alzheimer's disease by two independent groups (Odds ratio between 2.9-4.5). Given the key role of TREM2 in the

Published
2013

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