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2 results on '"Patarroyo JC"'

1. Immunodominant T-cell epitopes of MOG reside in its transmembrane and cytoplasmic domains in EAE.

Author

Zamvil, Scott, Shetty, A, Gupta, SG, Varrin-Doyer, M, Weber, MS, Prod'homme, T, Molnarfi, N, Ji, N, Nelson, PA, Patarroyo, JC, and Schulze-Topphoff, U

Abstract

Studies evaluating T-cell recognition of myelin oligodendrocyte glycoprotein (MOG) in multiple sclerosis (MS) and its model, experimental autoimmune encephalomyelitis (EAE), have focused mostly on its 117 amino acid (aa) extracellular domain, especially pe

Published
2014

2. MHC class II-dependent B cell APC function is required for induction of CNS autoimmunity independent of myelin-specific antibodies

Author

Zamvil, Scott, Molnarfi, N, Schulze-Topphoff, U, Weber, MS, Patarroyo, JC, Prod'homme, T, Varrin-Doyer, M, Shetty, A, Linington, C, Slavin, AJ, and Hidalgo, J

Abstract

Whether B cells serve as antigen-presenting cells (APCs) for activation of pathogenic T cells in the multiple sclerosis model experimental autoimmune encephalomyelitis (EAE) is unclear. To evaluate their role as APCs, we engineered mice selectively deficie

Published
2013

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