1. Vessel Wall MRI Enhancement in Noninflammatory Cerebral Amyloid Angiopathy
- Author
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Hao, Q, Tsankova, NM, Shoirah, H, Kellner, CP, and Nael, K
- Subjects
Biomedical and Clinical Sciences ,Chemical Sciences ,Physical Chemistry ,Clinical Sciences ,Neurosciences ,Acquired Cognitive Impairment ,Neurodegenerative ,Brain Disorders ,Dementia ,Clinical Research ,Aetiology ,2.1 Biological and endogenous factors ,Cardiovascular ,Aged ,Amyloid beta-Peptides ,Arteries ,Brain ,Cerebral Amyloid Angiopathy ,Humans ,Magnetic Resonance Imaging ,Male ,Retrospective Studies ,Nuclear Medicine & Medical Imaging ,Clinical sciences ,Physical chemistry - Abstract
Cerebral amyloid angiopathy is characterized by deposition of amyloid-β fibrils in the walls of small-to-medium-sized blood vessels. In this retrospective review of 5 patients with histologically confirmed noninflammatory cerebral amyloid angiopathy, high-resolution vessel wall MRI showed arterial wall enhancement in 2 patients (40%). Despite common consensus of equating vessel wall enhancement with inflammation, this report demonstrates that β-amyloid accumulation alone without inflammation can be associated with arterial wall enhancement in a subset of patients.
- Published
- 2020