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4 results on '"Acharya, NR"'

1. Expert opinion in the management of aqueous Deficient Dry Eye Disease (DED) Cornea and external eye diseases

Author

Acharya, Nisha, Lietman, Thomas, Sy, A, O'Brien, KS, Liu, MP, Cuddapah, PA, Acharya, NR, Lietman, TM, and Rose-Nussbaumer, J

Abstract

© 2015 Sy et al.Background: Dry eye disease (DED) affects millions of people worldwide. There are a variety of new treatments beyond traditional therapies such as preservative free artificial tears. Here, we conduct a survey to identify the most common tre

Published
2015

2. Improvement in corneal scarring following bacterial keratitis

Author

McClintic, SM, Srinivasan, M, Mascarenhas, J, Greninger, DA, Acharya, NR, Lietman, TM, and Keenan, JD

Subjects
Biomedical and Clinical Sciences, Ophthalmology and Optometry, Clinical Trials and Supportive Activities, Clinical Research, Physical Injury - Accidents and Adverse Effects, Eye Disease and Disorders of Vision, 6.1 Pharmaceuticals, Evaluation of treatments and therapeutic interventions, Eye, Adult, Aged, Aza Compounds, Cicatrix, Corneal Ulcer, Eye Infections, Bacterial, Female, Fluoroquinolones, Humans, Male, Middle Aged, Moxifloxacin, Ophthalmic Solutions, Pneumococcal Infections, Prednisolone, Pseudomonas Infections, Quinolines, Vision Disorders, Visual Acuity, corneal ulcer, corneal scar, SCUT, Clinical Sciences, Immunology, Opthalmology and Optometry, Ophthalmology & Optometry, Ophthalmology and optometry
Abstract

AimBacterial keratitis results in corneal scarring and subsequent visual impairment. The long-term evolution of corneal scars has not been well described. In this case series, we identified patients who had improvement in corneal scarring and visual acuity from a clinical trial for bacterial keratitis.MethodsWe searched the records of the Steroids for Corneal Ulcers Trial (SCUT) for patients who had improvement in vision between the 3-month and 12-month visits and reviewed their clinical photographs.ResultsOf the 500 patients enrolled in SCUT, five patients with large central corneal scars due to bacterial keratitis are presented. All experienced improvement in rigid contact lens-corrected visual acuity from months 3 to 12. All patients also had marked improvement in corneal opacity during the same time period. None of the patients opted to have penetrating keratoplasty.ConclusionsCorneal scars may continue to improve even many months after a bacterial corneal ulcer has healed. The corneal remodeling can be accompanied by considerable improvement in visual acuity, such that corneal transplantation may not be necessary.

Published
2013

3. Corticosteroid-sparing therapy: Practice patterns among uveitis specialists

Author

Acharya, Nisha, Esterberg, E, and Acharya, NR

Abstract

Purpose: This study aims to determine uveitis specialists' practice patterns, preferences, and perceptions of corticosteroid-sparing therapies for the initial treatment of chronic noninfectious uveitis. Methods: A survey was distributed to the American Uve

Published
2012

4. Predictors of outcome in fungal keratitis.

Author

Prajna, N Venkatesh, Krishnan, T, Mascarenhas, J, Srinivasan, M, Oldenburg, CE, Toutain-Kidd, CM, Sy, A, McLeod, SD, Zegans, ME, Acharya, NR, Lietman, TM, and Porco, TC

Subjects
Humans, Corneal Ulcer, Eye Infections, Fungal, Natamycin, Triazoles, Pyrimidines, Ophthalmic Solutions, Antifungal Agents, Prognosis, Debridement, Administration, Topical, Risk Factors, Prospective Studies, Double-Blind Method, Visual Acuity, Time Factors, Female, Male, Corneal Perforation, Re-Epithelialization, Voriconazole, Outcome and Process Assessment, Health Care, Eye Disease and Disorders of Vision, Clinical Research, Eye, fungus, keratitis, risk factors, Clinical Sciences, Immunology, Opthalmology and Optometry, Ophthalmology & Optometry
Abstract

PurposeTo analyse predictors of clinical outcome in fungal keratitis.MethodsData was collected during a prospective, randomized, controlled, double-masked clinical trial of treatment for fungal keratitis. Clinical features at presentation and demographics were collected at the enrollment visit for all patients. Pre-specified clinical outcomes included 3-month visual acuity and infiltrate/scar size, time to re-epithelialization, and corneal perforation. A separate multivariable model with each outcome as the dependent variable included all predictor variables.ResultsPredictors for worse 3-month visual acuity include older age (P=0.024), worse presentation visual acuity (P

Published
2012

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