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Established as the definitive reference for the IVF clinic, the sixth edition has been extensively revised, with the addition of several important new contributions on clinical topics, including The use of digitalization and precision medicine in the IVF clinic, The environment and reproduction, The use of gonadotropin-releasing hormone agonists and the efficiency of IVF, Controlled ovarian stimulation for freeze-all cycles, Immunology in ART, Home monitoring of ART cycles, Luteal-phase support in ART, The POSEIDON stratification of ‘low prognosis'patients in ART, Controlled ovarian stimulation for low responder patients, Adjuvants for poor responders, Innovative therapies in diminished ovarian reserve and primary ovarian insufficiency patients, and Fertility options for transgender and nonbinary individuals. As previously, methods, protocols, and techniques of choice are presented by IVF pioneers and eminent international experts.

In this textbook the life course approach to women's health is applied to the clinical practice of Obstetrics and Gynaecology. Life is considered a continuum ‘from the cradle to the grave', where each life stage affects the individual's health and wellbeing and that of future generations. This approach in obstetric and gynaecological patient care provides a path towards healthy ageing, with specific attention for lifestyle, prevention and social context. By managing not only disease, but also the health of the population, women's healthcare providers will deliver future care in a much more multidisciplinary fashion. In this second edition of Textbook of Obstetrics and Gynaecology: A life course approach all texts have been updated and new chapters have been added on transgender care, multiple pregnancy, clinical placenta disorders, endometriosis and obstetric emergencies by an outstanding team of authors. The illustrative material has also been expanded including new introductory infographics to each life stage part of the book and new 3D video animations in the e-book version. The textbook should serve as a reference not only for medical and midwifery students but also for gynaecologists in training and other clinicians who have the privilege of caring for women and their families, from the earliest moments in life onwards.

Design, Characterization and Fabrication of Polymer Scaffolds for Tissue Engineering covers core elements of scaffold design, from properties and characterization of polymeric scaffolds to fabrication techniques and the structure-property relationship. Particular attention is given to the cell-scaffold interaction at the molecular level, helping the reader understand and adapt scaffold design to improve biocompatibility and function. The book goes on to discuss a range of tissue engineering applications for polymeric scaffolds, including bone, nerve, cardiac and fibroblast tissue engineering. Design, Characterization and Fabrication of Polymer Scaffolds for Tissue Engineering is an important, interdisciplinary work of relevance to materials scientists, polymer scientists, biomedical engineers and those working regenerative medicine. - Helps the reader determine the most appropriate polymer for scaffold design by characterization, properties and structure-property relationship - Discusses material-cell interactions at the molecular level, aiding in determining suitability - Covers core elements of scaffold design, including fabrication techniques

This book gathers high-quality research papers presented at the 4th International Conference on Frontiers in Computing and Systems (COMSYS 2023) held at Indian Institute of Technology Mandi, Himachal Pradesh, India, during 16–17 October 2023. The book is divided into two volumes, and it covers research in “cyber-physical systems for real-life applications” pertaining to AI, machine learning and data science; devices, circuits, and systems; computational biology, biomedical informatics, and network medicine; communication networks, cloud computing, and IoT; image, video, and signal processing; and security and privacy.

Now in its second edition, Hematology Board Review has been thoroughly revised and updated to contain the latest information that fellows and clinicians need to successfully prepare for the Hematology Certification Exam administered by the American Board of Internal Medicine (ABIM). The new edition now contains even more high yield board study content and review questions. For the hematology-oncology fellow, hematologist, medical oncologist, or internist looking to review a given disease or blueprint category prior to their examination, this extremely practical study guide provides the pertinent points of emphasis that are often highlighted on the exam. Chapters on blood disorders and disease sites cover epidemiology, etiology and risk factors, staging, signs and symptoms, diagnostic criteria, indications for treatment, prognostic factors, treatment recommendations, and special considerations. Clinical pearls on other major subspecialty areas found on the exam include hematologic emergencies and supportive care, transfusion medicine, stem cell biology and hematopoiesis, cellular therapy, management of hematologic disease, complications after cellular therapy, and biostatistics. With 240 practice questions, detailed rationales, and a convenient print + digital package, Hematology Board Review gives you the tools to study your way and the confidence to pass the first time! Key Features: Aligns with the latest Hematology Certification Exam ABIM blueprint Provides a comprehensive yet concise review of all hematologic malignancies, blood disorders, transfusion medicine, cellular therapy, standard treatment regimens, and biostatistics Revised to include new treatment recommendations and FDA approvals Includes end-of-chapter assessment questions with detailed rationales - a total of 240 questions

This text fills the gap between medical specialties in this topic, covering the dermatological diseases appearing during or affected by pregnancy; it also looks at safe drug usage and the cosmetic and aesthetic concerns of the pregnant woman. Most of the conditions discussed require a combined approach and treatment by the dermatologist and gynecologist and obstetrician, and this text establishes a united therapeutic approach for all practitioners. Fills the gap between the various specialties involved in managing skin diseases in pregnant patients Offers a unified approach for all health professionals managing pregnant patients Presents a practical and detailed clinical resource

This fully-updated third edition of Scleroderma: From Pathogenesis to Comprehensive Managementbuilds upon the well-regarded approach in the previous editions to provide integrated, concise, and up-to-date synthesis of current concepts of pathogenesis and modern approaches to management of systemic sclerosis (scleroderma). With a multidisciplinary approach to comprehensive care, this book is easily accessible for health care professionals in many fields. Comprised of the authoritative work of international experts, the new edition includes extensive updated material reflecting major developments in the field. It presents a succinct and thoughtful synthesis of current pathomechanistic concepts, providing a valuable reference tool for basic and translational investigators working in the field. Scleroderma: From Pathogenesis to Comprehensive Management serves as an essential, all-inclusive and fully up to date resource for rheumatologists, pulmonologists, cardiologists, gastroenterologists, nephrologists and all those involved in the care of scleroderma patients.

A Unified System Fitness Design proposes a new fitness framework that encompasses all fitness indicators in a holistic and comprehensive manner, striving to provide a comprehensive and inclusive definition of physical fitness, one that considers all attributes contributing to overall well-being, and crafting a flexible framework that can adapt to diverse contexts and purposes of physical fitness assessments. This new book is divided into three parts. Part I explores redefining and reconstructing the concepts of an inclusive and holistic fitness framework. In Part II, the reader is encouraged to embark on a journey to discover the interconnected system functions of physiological health, homeostasis, motor control, and energy regulation. Part III reinforces the role of wellness in the Unified Systems Fitness Design, guided by the principles of inclusion and equity, in the decision-making process. Finally, the perpetual complementation theory emerged from the design, making sense of the cyclical connection between the system functions for health and skill and strengthening the Health-Ability-Task Suitability (HATS) Framework. There are still many uncharted territories in the realm of fitness and wellness. A Unified System Fitness Design addresses these gaps in the literature and practice and seeks to inspire a transformative worldview that urges the reader to question the existing paradigms and explore innovative, inclusive approaches that cater to people with unique needs. In doing so, this exciting new volume aims to establish a common language for researchers and practitioners in the field, offering accurate and concise descriptions of each fitness component and its associated indicators in a universally understood terminology.

For over 40 years, Yen & Jaffe's Reproductive Endocrinology has been the gold standard text of both basic science and clinical practice of the full range of female and male reproductive disorders. The fully revised 9th Edition continues this tradition of excellence with complete coverage, including up-to-date information on impaired fertility, infertility, recurrent pregnancy loss, problems of sexual development, menstrual disturbances, fibroids, endometriosis, female and male reproductive aging, fertility preservation, assisted reproduction technologies including ovarian stimulation and ovulation induction, transgender hormonal treatment, contraception, and more. An outstanding editorial board and other global experts in the field share their knowledge and expertise to keep you abreast of current science and practice in endocrinology. - Includes new chapters on Meiosis, Fertilization and Embryo Development; Recurrent Pregnancy Loss; Uterus Transplantation; Mitochondrial Transplantation and Gene Editing; and Germs Cells Developed In Vitro. - Provides extensively revised information on contemporary practices in assisted reproduction, fertility preservation, and ovulation induction. - Provides an online video library that highlights surgical procedures, diagnostic imaging, and functional ultrasound imaging. - Adds three new members to the exceptional editorial team: Drs. Anuja Dokras, Carmen J. Williams, and Zev Williams. - Features full-color, high-quality illustrations that clearly depict basic anatomic structures, endocrine processes, and cell function and dysfunction. - Includes bulleted lists under major headings in each chapter for quick, at-a-glance summaries of every section. - Lists Top References at the end of each chapter that distill the most important references for research underpinnings, to complement the complete online reference list. - An eBook version is included with purchase. The eBook allows you to access all of the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud.

This book provides theoretical and empirical knowledge to researchers using stereological techniques. Most of the commonly used techniques are given in this book. Each of the techniques gives an excellent opportunity to researchers who would like to work with tissues in three dimensions. Accurate and valuable quantitative data on the tissues and organs can be obtained by employing those techniques. This book contains 32 chapters in which the authors present rich data that is analyzed, discussed and interpreted, including morpho-quantitative, histomorphometry and qualitative values.

Focusing on the anatomy of the head and neck, this book begins at the cellular level of development, detailing bone, muscle, blood supply, and innervation along the way. It illustrates the origin of each tissue structure to aid in making prognoses beyond the surface deformation, offering typical issues seen in the craniofacial region, for example. Written by a pediatric Craniofacial plastic surgeon and intended for clinicians and residents in the areas of plastic surgery, ENT, maxillofacial surgery, and orthodontistry, this book is the first of its kind to focus so intently on evolution of the craniofacial structure. It is neatly broken up into two distinct sections.The first section is meant for readers to gain a fundamental understanding of the development of craniofacial structures, from embryo onward, relying on the concepts of the Neuromeric Theory. The chapters in the first section of the book trace the development of the typical patient. The second section offers clinical examples of how the Neuromeric Theory can be used to repair or reconstruct various regions of the head and neck. Craniofacial clefts, including cleft lip and palate, ocular hypotelorism, anencephaly, craniosynostosis and more are detailed. Understanding the formation of the tissue structures involved in any given genetic deformation or anomaly enables the clinician to provide a more satisfying outcome for the patient, both structurally and aesthetically. New and current therapeutic options are explored and supported through original illustrations and photographs to aid in determining the best treatment for each individual patient.Embryological Principles of Craniofacial Structure bridges the gap between introductory books on the basic anatomy of the head and neck and the detailed understanding required for corrective surgery of craniofacial defects.

This book provides a comprehensive overview of the development of the human central nervous system (CNS) in the context of its many developmental disorders due to genetic, environmental and hypoxic/ischaemic causes. The book contains three general, introductory chapters in which an overview of the development of the human brain and spinal cord, a summary of mechanisms of development as obtained in experimental studies in various invertebrates and vertebrates, and an overview of the causes of congenital malformations are presented. The developmental disorders of the human brain and spinal cord are presented in a regional, more or less segmental way, starting with neurulation and neural tube defects, and ending with developmental disorders of the cerebral cortex. These chapters are abundantly illustrated in colour with carefully chosen clinical case studies with imaging data, and when available, postmortem verification of the developmental disorders involved.In thethird edition, more emphasis has been given to the developmental ontology based on the prosomeric approach, and fetal development. Prenatal diagnosis by ultrasound, MRI and DTI, and classifications of developmental disorders have been updated. A number of new Clinical Cases have been included. Several new co-authors participate in various chapters. The book is intended for advanced medical students, and all those clinicians working with children and adults with developmental disorders of the CNS. Unique to the book is the integration of data from human embryology, experimental and molecular findings in mice in particular, imaging and developmental neuropathology.

Cellular Lipid in Health and Disease presents a comprehensive and systematic coverage of the various roles lipids play in human biology. This book is organized in four parts covering the foundational concepts of lipid biology all the way to the therapeutic opportunities they present. The first part is dedicated to the basic concepts of cellular lipid, the roles it plays in the cell, structure and physiology, regulation mechanisms, storage, and utilization. The second part is focused on lipid metabolism, covering the organelles involved in lipid trafficking, metabolism in aging, cholesterol homeostasis, lipid droplets (LDs), and lipid oxidation. Part three is dedicated to the roles lipids play in specific disease states including renal, metabolic, cardiovascular, and fatty liver diseases. Other conditions include cancer, neurodegenerative diseases, and the intricate relationship between cellular lipids and autophagy. The final part covers therapeutic opportunities, including drug carrier systems, modeling lipid metabolism, and prevention therapeutics. Cellular Lipid in Health and Disease is a complete reference targeted at graduate students and early career researchers in cell biology, biochemistry, and pharmacology. Research physicians can also benefit from the foundational content and links to pathologies and therapeutic opportunities. - Offers a complete and systematic coverage of lipid biology - Provides foundational content and establishes the needed connections to translational aspects of the research in this area - Includes chapters on the therapeutic opportunities presented by lipids

A collection of important essays on the health and well-being of African Americans in the southern United States.For African Americans in the southern United States, the social determinants of health are influenced by a unique history that encompasses hundreds of years of slavery, injustices during the Jim Crow era, the Great Migration, the civil rights era, and contemporary experiences like the Black Lives Matter movement. In Black Health in the South, editors Steven S. Coughlin, Lovoria B. Williams, and Tabia Henry Akintobi bring together essays on this important subject from top public health experts.Black activists, physicians, and communities continue to battle inequities and structural problems that include poverty, inadequate access to health care, incarceration, a lack of transportation, and food insecurity. As the result of redlining and other historical and contemporary injustices, African Americans are less likely to own a home or to have equity, which places them in danger of financial ruin if they experience an illness such as a heart attack, stroke, or cancer, for which they are often at greater risk due to many social and environmental factors. At the same time, African American communities display many strengths and are often very resilient against these structural inequities. The use of community coalitions is a valuable approach for addressing health disparities in African American communities, and improving the cultural competence of health care providers further reduces the effects of health disparities.With essays spanning topics from culturally appropriate health care to faith-based interventions and the role of research networks in addressing disparities, this collection is pivotal for understanding the health of African Americans in the South. Public health scholars have examined racial disparities in health in the United States broadly and in specific cities, but this is the first edited collection to focus on African Americans in the South both as a whole and as a distinct population.

The book presents a multi-disciplinary approach to understanding mechanisms regulating the formation of mineral in vertebrate skeletal and dental tissues. The focus of the book is directed toward the mineralization process, an evolutionarily conserved system in which cells synthesize a complex and unique extracellular matrix into which mineral is deposited. Regulatory control is viewed though lenses that emphasize the genetic, physical-chemical, biochemical, structural, cellular and extracellular aspects of the mineralization process as they relate to crystal nucleation, growth and maturation. Throughout the book, defects in regulation at the genetic and transcriptional levels are linked to the numerous clinical problems associated with the mineralization of bone, cartilage, tendon, tooth, and soft tissues. The book serves as a comprehensive text for basic scientists and scholars working in the many areas that comprise hard tissue research, as well as undergraduate and graduate students, postdoctoral fellows and those contemplating working in the field of biomineralization or who need a review of a specific mineralization topic. The information contained in the book is relevant for clinicians and clinical scientists in the fields of orthopaedic surgery, veterinary medicine, dentistry, endocrinology, aging and genetics.

Stem Cells and Signaling Pathways provides mechanistic insights into the role of stem cells to combat the COVID-19 outbreak and other pathologies where a cytokine storm is the cause of concern for e.g., radiation exposure, multiple organ failure and sepsis. The advent of SARS-CoV-2 resulted in a global pandemic, putting individuals with other comorbidities at a higher risk of infection. The whole world witnessed a massive shortage of medical and other essential supplies needed to combat the virus. That said, stem cell therapy has emerged as a potential treatment for viral diseases, including but not limited to COVID-19. Interestingly, the clinical trials in the patients having COVID-19 complications depicted faster recovery in patients post mesenchymal stem cells therapy owing to the decreased cytokines levels, anti-viral effects and regeneration of the infected tissue. - Provides a compilation of chapters dedicated to the study of the field with respect to properties of stem cells and their signaling pathways. It also provides detailed information on signaling pathways associated with stem cells - Provides a detailed and updated view of stem cell biology - Covers a wide range of areas within basic and translational research appropriate for scientists and clinicians engaged in studying the treatments for diseases from interdisciplinary perspectives - Highlights the use of different models for stem cell research, significance of stem cell signaling in drug discovery

••Selected for Doody's Core Titles® 2024 in Clinical Genetics•• Human Reproductive and Prenatal Genetics, Second Edition provides application-driven coverage of key topics in human reproductive and prenatal genetics, including genetic control underlying the development of the reproductive tracts and gametogenesis, the genetics of fertilization and implantation, the genetic basis of female and male infertility, as well as genetic and epigenetic aspects of assisted reproduction. Also examined are the genetics and epigenetics of the placenta in normal and abnormal pregnancy, preimplantation genetic diagnosis and screening, and cutting-edge advances in noninvasive prenatal screening, prenatal genetic counseling, and bioethical and medicolegal aspects of relevance in the lab and clinic. This new edition has been fully revised to address new and evolving technologies in human reproductive genetics, with new chapters added on chromatin landscapes and sex determination, genetic alterations of placental development and preeclampsia, metabolism and inflammation in PCOS, pre-implantational genetic testing, maternal genetic disorders, bioethics, and future applications. - Features chapter contributions from leading international scientists and clinicians - Provides in-depth coverage of key topics in human reproductive and prenatal genetics, including genetic controls, fertilization, placental development, embryo implantation, in vitro culture of the human embryo for the study of post-implantation development, and more - Identifies how researchers and clinicians can implement the latest genetic, epigenetic, and –omics-based approaches - Includes all new chapters on evolving technologies and recent genetic discoveries of relevance to reproductive medicine

Introducing'Polycystic Ovarian Syndrome (PCOS) and Our Biological Clock'- a groundbreaking book that sheds light on one of the most prevalent and misunderstood health conditions affecting women today. Within the pages of this book, readers will embark on a transformative journey of understanding as they unravel the intricate relationship between PCOS and the biological clock. Delving into the science behind PCOS, the authors demystify its causes, symptoms, and long-term implications. With a compassionate and holistic approach, they provide practical advice on managing symptoms, optimizing fertility, and improving overall well-being. This book is not only a comprehensive resource for women struggling with PCOS, but also an essential tool for healthcare professionals, researchers, and anyone seeking a deeper understanding of this complex condition. Its accessible language and evidence-based approach makes it an invaluable companion for individuals looking to unravel the mysteries of PCOS and make informed decisions about their health. “Polycystic Ovarian Syndrome (PCOS) and Our Biological Clock'stands as a beacon of knowledge, compassion, and empowerment, guiding readers towards a brighter future where PCOS no longer holds them back. Whether you're a woman battling PCOS, a concerned partner, or a healthcare provider looking to offer better care, this book is a must-read that will change lives and reshape the conversation surrounding PCOS.

Cancer Genes is a comprehensive list of the most critical genes known to contribute to cancer imitation and progression. The book delves into their location on each chromosome, providing valuable insights into the mechanisms of cancer gene dysregulation and genetic mutations which provide cancer cells with an advantage during each stage of tumorigenesis. The reference will familiarize readers with the location of cancer genes and equip them with the necessary information to identify relevant gene expression targets for research aimed at preventing the disease. The book is divided into two volumes focusing on cancer-causing genes found in chromosome pairs 1-12 (volume 1), and chromosomes 13-23 (volume 2). A key features of the book is a detailed reference list for advanced readers. The compilation is therefore a quick and handy reference on cancer causing genes for researchers, medical professionals, and anyone interested in understanding the genetic basis of cancer.

This updated reference covers diverse aspects of cerebellar development from a full range of viewpoints, including the epidemiology of cerebellar genetic disorders, developmental anatomy, cell biology, genetics, epigenetics, infectious diseases, and mechanisms involved in the regulation of cell fate, while also focusing on information that is relevant to clinicians caring for patients with cerebellar disorders. The chapters are written by experts in the field of cerebellar development, and the chapters cover diseases related to the cerebellum, along with their epidemiology, clinical features, assessment, and management. In addition to updating the content to cover the significant developments in the field since the first edition, the second edition will include new chapters on Non-Coding RNAs and Cerebellar Development, Development of the Fish Cerebellum, the Role of nNOS/NO on Cerebellar Development in Health and Disease, and rehabilitation in cerebellar ataxia. The effect of the COVID-19 on the cerebellum has been included in related chapters. Development of the Cerebellum from Molecular Aspects to Diseases, 2nd edition, is designed to be valuable reference for both neuroscientists and clinicians.

Advances in Clinical Chemistry, Volume 114, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians and research scientists. New sections in the updated release include Growth differentiation factor 15 (GDF-15) in kidney diseases, Alkaptonuria - past, present and future, Alcohol Consumption and Nutritional Biomarkers in Early-Stage Alcohol-Associated Liver Disease, Advances in Liquid Biopsy–Based Markers in NSCLC, D-dimer testing: a narrative review, Evolving Markers in Amyotrophic Lateral Sclerosis, and more. - Provides the most up-to-date technologies in clinical chemistry and clinical laboratory science - Authored by world-renowned clinical laboratory scientists, physicians and research scientists - Presents the international benchmark for novel analytical approaches in the clinical laboratory

This book covers all aspects of Surgically Facilitated Orthodontic Therapy and is intended to guide practitioners involved in dental interdisciplinary therapy to managing complex cases. It demonstrates the next level of collaboration through managing core problems of the patients and planning cases using digital dentistry for enhanced disclosed and more ideal outcomes. Methods for regaining space appropriation and dentoalveolar bone engineering are illustrated. Emphasis is placed on corticotomy assisted orthodontic therapy and 3D planning in order to help practitioner to achieve outcomes that were previously unrecognized. The book is written by leading experts in the field and is a rich source for periodontists, oral and maxillofacial surgeons, orthodontists and restorative clinicians interested in the subject.

This book presents the latest findings in the field of cardiac mechanobiology in health and disease.Cardiac mechanobiology provides knowledge of all aspects of mechanobiology of the heart. Cardiomyogenesis is discussed as well as the mechanobiology of cardiac remodeling and regeneration. The molecular mechanisms of mechanoperception and mechanotransduction in cardiomyocytes are explained, as well as stretch induced differentiation of cardiomyocytes derived from induced pluripotent stem cells. This volume of the series Cardiac and Vascular Biology complements the volume Vascular Mechanobiology in Physiology and Disease (volume 8) published in this series. The book is aimed at clinicians as well as researchers in cardiovascular biology, bioengineering and biophysics, and also represents an educational resource for young researchers and students in these fields.

Engineering and Physical Approaches to Cancer addresses the newest research at this interface between cancer biology and the physical sciences. Several chapters address the mechanobiology of collective and individual cell migration, including experimental, theoretical, and computational perspectives. Other chapters consider the crosstalk of biological, chemical, and physical cues in the tumor microenvironment, including the role of senescence, polyploid giant cells, TGF-beta, metabolism, and immune cells. Further, chapters focus on circulating tumor cells and metastatic colonization, highlighting both bioengineered models as well as diagnostic technologies. Further, this book features the work of emerging and diverse investigators in this field, who have already made impressive cross-disciplinary scientific contributions. This book is designed for a general audience, particularly researchers conversant in cancer biology but less familiar with engineering (and vice-versa). Thus, we envision that this book will be suitable for faculty, postdoctoral fellows, and advanced graduate students across medicine, biological sciences, and engineering. We also anticipate this book will be of interest to medical professionals and trainees, as well as researchers in the pharmaceutical and biomedical device industry.Describes physical aspects of cancer, including collective cell migration, the aberrant tumor microenvironment, circulating tumor cells, and metastatic colonization. First volume available on the topic of physical aspects of cancer

Degenerative Cervical Myelopathy: From Basic Science to Clinical Practice lays the foundation for understanding DCM manifestation, pathophysiology, diagnosis and treatment strategies. The book covers the latest basic and clinical research, updates on patient management strategies, and discusses promising neuroprotective therapies for the future of DCM care. Written by international experts across a range of topics related to degenerative cervical myelopathy, the book helps readers understand the challenges and future directions of patient management. As degenerative cervical myelopathy (DCM) is the leading cause of spinal cord dysfunction and one of the most common indications for spinal surgery worldwide, the term DCM encompasses a group of chronic, non-traumatic spinal cord injuries that occur due to degenerative changes in the cervical spine (e.g. disc spondylosis or repetitive dynamic injury from hyper-mobility). - Covers recent clinical trial advancements and the impact of trial findings - Presents recent clinical guidelines for the management of degenerative cervical myelopathy, providing readers with insights regarding the translation of research from bench to bedside - Provides readers with the skills needed to understand the translational pathway using real-life examples

Developed in partnership with the American Academy of Orthopaedic Surgeons (AAOS) and edited by internationally renowned experts Drs. Scott P. Bruder and Roy K. Aaron, Orthobiologics: Scientific and Clinical Solutions for Orthopaedic Surgeons provides authoritative, comprehensive coverage of this fast-growing field. This one-stop reference is an ideal resource, covering technology and basic science through specific clinical applications.

This book reviews state of the art of polymeric biomaterials for regenerative medicine and highlights advances in both fundamental science and clinical practice. It summarizes the latest techniques in polymeric scaffold fabrication, delivery carriers, physiochemical property modulation, as well as their influence on the adhesion and performance of biomolecules, cells, and tissues. It also describes methods for creating biofunctional surfaces/interfaces and subsequently modulating the host response to implantable materials. Lastly, it discusses the applications of biomaterials and constructs in soft-tissue regenerative medicine. It is a valuable resource for materials scientists and engineers wishing to identify research priorities to fulfill clinical needs and provides physicians with insights into emerging novel biomaterials. This integrated approach also offers engineering students a sense of the relevance of materials science in the development of novel therapeutic strategies. In the second edition, most of the chapters are updated according to the latest progress of this research field. A new chapter on nerve regeneration is also included.

This is an open access book. In honor of his 75th birthday, we reflect on the impact of the pioneering work of Alan Grodzinsky and his laboratory. This volume includes in-depth discussions of tissue electromechanics, mechanobiology and biomechanics, and matrix biology in addition to the latest advancements in understanding the pathogenesis, progression and treatment of osteoarthritis. Unique to this volume, we overview decades of groundbreaking research that set the stage for the latest efforts in the field, highlighting the legacy of one researcher and their trainees.

The editors have placed significant emphasis on conveying succinctly how this knowledge informs both the prevention and treatment of cardiovascular diseases. There are 11 sections covering 140 chapters written by around 250 renowned authors, including 1,000 figures and 400 tables and all the content has been colourfully and digitally enhanced with particular attention to the importance of using appropriate guidelines in the diagnosis and management of cardiovascular diseases. A topic on the latest practice impacting trials has also been incorporated in a dedicated chapter on landmark trials. The editors would like to highlight several exciting changes with a new addition of knowledge on genetics and a section on cardiac oncology.

Encyclopedia of Sleep and Circadian Rhythms, Second Edition, Six Volume Set is the most comprehensive work on sleep and circadian rhythms. This completely revised new edition, comprised of contributions from 450 renowned authorities in the field, covers what is new and known in the field. In addition to thorough coverage of the basics (physiology, sleep disorders etc.), this new edition includes a thorough examination of circadian rhythms that manage the sleep-wake cycle. Although this area is highly intertwined with sleep, it is a scientific discipline in and of itself, and will broaden the appeal of this work to health care providers and scientists. Other sections of interest explore consumer wearable devices to track sleep and circadian rhythms, artificial intelligence algorithms to detect sleep and abnormal sleep-related conditions, and new technology to treat sleep and circadian rhythm disorders. This book will be an ideal and primary reference resource for students, trainees, technologists, basic/clinical scientists, physicians, advanced practice providers, psychologists, nurses, and other medical and research personnel who want to explore any topic within the sleep and circadian rhythm field. - Provides the largest, most comprehensive publication in the field of sleep and circadian rhythms for non-specialists and readers from undergraduate level upwards, as well as advanced health care providers - Covers the latest, most up-to-date knowledge regarding sleep and circadian rhythms and contains material that reflects the newest technology in the field - Presents a new edition of the winner of the 2013 Prose Award for Multivolume Reference in Science from the Association of American Publishers - Includes rich illustrations that can be used as teaching aids, along with multimedia

'Oncology nursing is a unique specialty that requires continuous learning to stay up to date on cancer pathophysiology, cutting-edge drugs, and the evidence-based management of cancer and cancer treatment-related toxicities. The Oncology Nursing Society's (ONS's) second edition of Chemotherapy and Immunotherapy Guidelines and Recommendations for Practice provides nurses with the tools to understand how medications are used in cancer treatment, the effect of medication-related toxicities, and evidence-based recommendations to manage and treat these toxicities. This edition features many new cancer therapies approved since the 2019 publication. Each drug is categorized as chemotherapy, hormone, targeted, or immunotherapy agents. Extensive drug tables in the book provide nurses with tips for managing patients receiving these drugs. The expansion of oral antineoplastic therapies, alone or in combination with infusion therapy, requires that nurses review a patient's complete cancer treatment plan and consider the side effects, toxicities, and adherence to oral drugs to ensure patient tolerance and efficacy. This second edition has seen content expanded on the topic of genomics as we move forward in the world of personalized oncology. Health equity is approached with information discussing financial distress, cultural disparities, and health literacy. The latest guidelines and recommendations for treatment, symptom management, and survivorship have been integrated into this new text. This edition features a QR code, provided with the purchase of this book, to download quarterly drug updates. You will see new evidence related to many aspects of cancer nursing care incorporated into this edition, such as hypersensitivity response, safe handling of hazardous drugs, and more. The editors want to thank all of the contributors to this edition who worked tirelessly, despite a pandemic, to make this new edition a reality. This work builds on the knowledge of many generations of oncology nurses and has been used nationally and internationally to guide oncology nursing practice. We are proud to continue to serve oncology nurses worldwide with an essential resource to guide their practice'--

The second edition comprehensively reviews the wide field of rare pulmonary diseases. Issues such as less common diseases affecting the airways, systematic disorders with lung involvement, interstitial lung diseases, and many other orphan conditions of the lungs are explored in this book. The progress and advances made in the field and the limited number of patients presenting each condition makes it very difficult for clinicians to be up-to-date in this field. Readers will discover how to diagnose and manage these rare orphan diseases. Orphan Lung Diseases: A Clinical Guide to Rare Lung Disease is a practical, informative book written by a team of international authors with much experience in rare pulmonary diseases Orphan Lung Diseases: A Clinical Guide to Rare Lung Disease, second edition provides synthesized and easily accessible information about the main orphan lung diseases, to aid clinicians in charge of patients with rare disease,or who consider the diagnosis of a rare disease in their patient. It is a practical, informative guide written by a team of international experienced authors in rare pulmonary diseases.

The book is an introduction to nanomedicine informed by a philosophical reflection about the domain and recent developments. It is an overview of the field, sketching out the main areas of current investment and research. The authors present some case-studies illustrating the different areas of research (nanopharmacy, theranostics and patient monitoring) as well as reflecting on the risks that accompany it, such as unanticipated impacts on human health and environmental toxicity. This introduction to a fast-growing field in modern medical research is of great interest to researchers working in many disciplines as well as the general public. In addition to an overview of the work currently ongoing, the authors critically assess these projects from an ethical and philosophical perspective.Key Features Provides an overview of nanomedicine Employs a reflective and coherent critical evaluation of the benefits and risks of nanomedicine Written in an accessible manner intended for a wide audience Related TitlesHehenberger, M. Nanomedicine: Science, Business, and impact (ISBN 978-9-8146-1376-7).Beg, S., et al. Nanomedicine for the treatment of Disease: From Concept to Application (ISBN 978-1-7746-3443-1)Brenner, S. The Clinical Nanomedicine Handbook (ISBN 978-1-1380-7578-8)

Glycolysis: Tissue-Specific Metabolic Regulation in Physio-Pathological Conditions provides an integrated overview of glycolysis, spanning basic biochemistry, patho-physiology and therapeutic applications. The book also instructs in methods available to study the involvement of the glycolytic events in healthy biology and disease pathology. It begins with an overview of fundamental glycobiology followed by chapters dedicated to glycolysis physiology in organs and systems, pathologic conditions related to glycolytic alterations, glycolysis as a therapeutic target and in drug discovery efforts, and methodological approaches to advance new glycolysis research. Disease areas considered range from cancer to heart failure, diabetes, inborn glycolytic pathway defects, hematologic malignancies, osteoporosis, neurodegenerative diseases and viral Infections. Omics and computational modeling, interactive study methods, and glycolysis flux measurement are described in detail, with step-by-step descriptions of experimental protocols, set-up and analysis. - Features chapter contributions from international leaders in the field - Spans fundamental aspects of glycolysis, patho-physiology and drug discovery - Includes step-by-step instruction in a range of research protocols, ranging from Omics to interactive analysis and measuring glycolysis flux

Mechanisms of Morphogenesis, Third Edition offers a bottom-up discussion of mechanisms of cell and tissue morphogenesis in a diverse array of organisms, including prokaryotes, animals, plants and fungi. Across foundational, applied and methods-based chapters, this book examines molecular nano-machines cooperation, generate cell shape, direct cell migration, and shape, form and rates of growth of various tissues in the body. Each topic is illustrated with experimental data from real systems, with particular reference to gaps in current knowledge and likely future developments, along with strategies to apply basic morphogenesis science across ever evolving applications. Newly added chapters feature case-study-driven discussions of morphogenesis in natural embryos and organoids, and illustrate how pathological morphogenesis can generate variants of body form. This edition has also been updated with analysis of large-scale and scale-invariant mechanisms, for example, morphogenesis by differential growth in mechanically connected tissues. - Includes over 200 full color figures and charts - Offers an integrated view of theoretical developmental biology and computer modeling with laboratory-based discoveries - Includes applied, case-study-driven discussion of experimental techniques - Is organized around principles and mechanisms, using them to integrate discoveries from a range of organisms and systems across new applications - Covers recent developments in morphogenesis research, including morphogenesis in organoids, other engineered tissues, and an analysis of large-scale and scale-invariant mechanisms

Volume 1:Biofabrication aims to produce artificially manufactured tissues and organs, potentially revolutionizing conventional paradigm of clinical practice in treating diseases and extending the life span and quality of human beings. In this volume, we invite notable experts in the field of biofabrication and biomanufacturing to summarize recent rapid progress in this field from multifaceted aspects covering biofabrication techniques and building materials such as scaffold and living cells. Specifically, a focus is placed on a variety of techniques derived from 3D bioprinting and bioassembly strategies, such as acoustic assembly and electrofabrication. Moreover, principles and strategies for choosing hydrogels and polymers for biofabrication are also heavily discussed. Overall, this book creates a good opportunity for undergraduate and postgraduate students as well as bioengineers and medical researchers who wish to gain a fundamental understanding of current status and future trends in biofabrication and biomanufacturing.Volume 2:Infertility has become a significant psychosocial burden affecting the lives of couples who cannot reproduce naturally. Advanced reproductive technologies (ARTs) are being developed to treat infertility. This handbook explores significant development of ARTs for fertility testing, selection of sperm, oocyte and embryo, reproductive monitors, automation in embryology, and fertility preservation. This volume provides a comprehensive overview of the myriad of emerging technologies and systems that are being utilized or will be utilized in near future in reproductive clinics. Overall this book creates a good opportunity for undergraduate and postgraduate students as well as scientists and medical researchers who wish to gain fundamental understanding of current status and future trends in fertility and reproductive medicine.Volume 3:Healthcare industry has a notable paradigm transition from centralized care to the point-of-care (POC). During this metamorphosis, a number of new technologies and strategies have been adapted to the current practice, addressing the existing challenges in the fields of medicine and biology. All the efforts aim to improve the clinical management and the effectiveness and quality of care. In particular, diagnostics has pivotal roles in guiding clinical management for the most effective treatment to control and cure the disease. In contrast to the existing diagnostic strategies employing bulky-sized tools, expensive infrastructure, laborious protocols, and lengthy processing steps, the contribution of biosensors to current healthcare system, especially to diagnostics, is paramount. The unprecedented and admirable characteristics of biosensing strategies have expanded our knowledge on medicine and biology by harmonizing materials science, chemistry, physics, and engineering. We believe that biosensors applied to disease diagnostics will not only garner more attention in clinical research to decipher disease biology and mechanism, and also, stimulate innovative perspectives in artificial intelligence (AI) and internet of things (IoT) synergistically, thereby their more facile adaptation to daily-use. Overall this book creates a good opportunity for undergraduate and postgraduate students as well as scientists and medical researchers who wish to gain fundamental understanding of current status and future trends in diagnostic technologies.

This monograph presents to the reader an extensive and comprehensive description of individual BMPs. Their role in signal transduction is presented. A more specific description of the historical background, classification with a clear understanding of its physiology and mechanism of action are elaborated upon. This monograph sequentially depicts all the recent evidence supporting the use of BMPs in therapeutic interventions concerning periodontal bony defects, implant dentistry, non-union fractures, and osteoporosis, with more emphasis on periodontal regeneration. This book also presents a clear understanding of the genetic components, including naturally occurring mutations in BMPs and related genes. Successful targeted treatments, presented with updated and varied options, stand as a remarkable finding in our book which we sincerely feel to be more appropriate, easy to understand and analytically useful for treating clinicians.

Cats are one of the most popular pets in the world and cat owners want advanced veterinary care. There is a growing interest in purebred cats which requires the highest quality reproductive care from the general veterinary practitioners. In Feline Reproduction, all aspects of reproduction in the queen and the tom are presented by a global author team. Beginning with basic anatomy and normal reproduction, this book reviews practical knowledge about feline pregnancy, neonatal care, breeding soundness exams, and semen cryopreservation. This book also provides the most current and comprehensive information about abnormal conditions affecting feline reproduction, such as infertility, spontaneous abortion and contraception. Covering both pets and nondomestic species, this feline reproduction book will prove to be essential for the general veterinary practitioner, veterinary student, animal scientist, and experienced cat breeder.

This book describes the recent advancement of basic research on the biology of aging and longevity studies in various organisms, as well as the neurobiology of aging and neurodegeneration mechanisms. Chapters present new findings and conceptual developments concerning the basic mechanisms of aging and longevity determination. As a follow-up volume to the previous book Aging Mechanisms (2015), it overviews the rapid progress of aging research introducing new topics from leading laboratories in Japan. Chapter contributors are selected based on recent scientific achievements on the mechanisms of aging in various model organisms, including yeast, worm (C. elegans), fly (Drosophila), mice, and rats. Chapters are ordered from the discussion on molecular and cellular levels to physiological and systemic levels. The book also provides an overview of aging science in the region and helps readers quickly grasp who is doing what in this research area. As the aging of population becomes an ever more pressing issue in Asia, advancing the understanding of basic mechanisms of organism aging and longevity determination will be crucial to developing more effective therapies and protective strategies. Researchers and graduate students in biomedical aging research will find this as a rich source of information and a stimulus to novel research directions.

Keeping up to date with advances in comprehensive ophthalmology and in the ophthalmic sub-specialties is extremely difficult because of the accelerating rapidity with which new information and technology become available and the diminishing time and opportunity for practitioners and trainees to read and learn. The first edition of Albert and Jakobiec's Principles and Practice (1994) was conceived with the idea of utilizing an electronic, updated version in which the chapters were revised by the chapter authors on an annual or semi-annual basis, but the technology was not sufficiently advanced to achieve this goal. Subsequent editions (2000 and 2008) were organized by Saunders and the last published by Elsevier (of which Springer has obtained the complete rights to move forward with the 4th edition). For nearly three decades, this text has provided its readers with authoritative and comprehensive coverage of clinical ophthalmology, written and edited by a group of authors who represented a “Who's Who” in ophthalmology. By using Springer's Meteor platform, with its ability to allow authors and editors access to updating their chapters online annually/semi-annually, and with the recruitment of select chapter authors, this work's usefulness as the standard text in ophthalmology will be maintained and expanded upon by Springer. The 4th edition of this comprehensive and authoritative text is written by hundreds of the most distinguished authorities from around the world and edited by four leaders in the field, providing today's best answers to every question that arises in ophthalmology practice. Richly illustrated with thousands of high quality, full color, clinically-relevant images, Albert and Jakobiec's Principles and Practice of Ophthalmology, 4th Edition covers every scientific and clinical principle in ophthalmology, ensuring that the reader will always be able to find the guidance needed to diagnose and manage patients'ocular problems and meet today's standards of care. Written for practicing ophthalmologists and trainees, this book delivers in-depth guidance on new diagnostic approaches, operative techniques, and treatment options, as well as coherent explanations of new scientific concept and its clinical importance. The 4th edition will prove to be the source every practicing clinician needs to efficiently and confidently overcome any clinical challenge they may face. Updates include new chapters on anterior and posterior segment diseases, as well as chapters more focused on treatment, plus thousands of new, high-quality, color images and illustrations, updated references, and information on the most cutting-edge technology used by clinicians in their practices today. Additionally, readers will enjoy the same, user-friendly, full-color design they remember from the previous edition, complete with many at-a-glance summary tables, algorithms, boxes, and diagrams that allow the reader to locate the assistance needed more rapidly than ever.

The multi-authored, multi-institutional, and multi-specialty-based text is designed as a valuable resource for surgeons working on the maxillofacial region. Meant to be a clinically based history of the past, the present, and the future of the field, this is a one-of-a-kind text that will cater to a variety of professions: from oral & maxillofacial surgeons, plastic and reconstructive surgeons, otolaryngologists – head and neck surgeons, cosmetic surgeons and the general dental practitioner. The History of Maxillofacial Surgery: An Evidence-Based Journey is divided into three sections for ease of understanding: The first section gives an overview of the early history; the second section provides a discussion of conventional procedures; and the third section gives a history of advanced procedures and techniques. By understanding the fundamental procedures and techniques of the field, practitioners can continue to further the field by building upon thepast. Including historic case studies paired with real patient photos, this text details why professionals do what they do today with insight directly from the clinic. To provide a unique perspective the book is edited by three individuals at different stages of their careers. Each chapter is authored by a young surgeon paired with a seasoned surgeon.

Biological Macromolecules: Bioactivity and Biomedical Applications presents a comprehensive study of biomacromolecules and their potential use in various biomedical applications. Consisting of four sections, the book begins with an overview of the key sources, properties and functions of biomacromolecules, covering the foundational knowledge required for study on the topic. It then progresses to a discussion of the various bioactive components of biomacromolecules. Individual chapters explore a range of potential bioactivities, considering the use of biomacromolecules as nutraceuticals, antioxidants, antimicrobials, anticancer agents, and antidiabetics, among others. The third section of the book focuses on specific applications of biomacromolecules, ranging from drug delivery and wound management to tissue engineering and enzyme immobilization. This focus on the various practical uses of biological macromolecules provide an interdisciplinary assessment of their function in practice. The final section explores the key challenges and future perspectives on biological macromolecules in biomedicine. - Covers a variety of different biomacromolecules, including carbohydrates, lipids, proteins, and nucleic acids in plants, fungi, animals, and microbiological resources - Discusses a range of applicable areas where biomacromolecules play a significant role, such as drug delivery, wound management, and regenerative medicine - Includes a detailed overview of biomacromolecule bioactivity and properties - Features chapters on research challenges, evolving applications, and future perspectives

This book is part of a two-part volume book that highlights the latest advances in innovative bioceramics applied in the highly interdisciplinary area referred to as “translational medicine”. This volume covers the basic principles and techniques used in the manufacture of bioceramics and biocomposites for various biomedical applications including drug delivery, implantable bionics and the development of the cardiac pacemaker, and bone tissue engineering. Furthermore, self-healing materials have been attracting increasing interest in both engineering and medical applications during the past two decades. Self-healing hydrogels are particularly interesting because of their ability to repair structural damages and recover their original functions, specifically in tissue engineering.

The Pituitary, Fifth Edition continues the tradition of a cogent blend of basic science and clinical medicine. The comprehensive text written by expert pituitary scholars is devoted to the pathogenesis, diagnosis and treatment of pituitary disorders. The new fifth edition has been extensively revised to reflect the most recent data on new research advances in tumorigenesis and new therapeutic approaches for pituitary tumors, particularly in acromegaly and Cushing disease. Notably, new chapters devoted to the Pituitary-Immune Interface and Pituitary Radiotherapy have been included, along with a chapter on Aggressive Pituitary Adenomas developed to align with the WHOs Classification of Pituitary Tumors. Furthermore, new authors have been invited, ensuring a fresh perspective on critical issues in the field. This extensive body of knowledge is useful for students, trainees, physicians, and scientists who need to understand critical pituitary functions and how to care for patients with pituitary disorders. - Provides a detailed description of the wide spectrum of clinical disorders emanating from the dysfunction of the'master gland and the fundamental science underlying pituitary dysfunction - Brings together pituitary experts from all areas of research and practice who take readers all the way from bench research to genomic and proteomic analysis, clinical analysis, and new therapeutic approaches - Describes the mechanisms for disease pathogenesis, including both subcellular and extrinsic mechanisms that subserve normal and disordered pituitary hormone secretion and action

iPSCs - State of the Science, Volume Sixteen, the latest release in the Advances in Stem Cell Biology series, is an expansive collection of information and new discoveries in the field. This volume addresses the importance of induced pluripotent stems cells and how can they be derived from different sources. It addresses advances in research in induced pluripotent stem cells from alternate sources, such as spermatogonial stem cells, ovarian tissue, cancer cells, and many other sources. It is written for researchers and scientists in stem cell therapy, cell biology, regenerative medicine and organ transplantation, and is contributed by world-renowned authors. - Provides an overview of the fast-moving field of stem cell biology and function, regenerative medicine and therapeutics - Covers iPSCs derived from amniotic fluid, oral tissue derived iPSCs, muse cells, postmortem tissue, and much more - Contributed by world-renowned experts in the field

Scientific Principles of Adipose Stem Cells provides readers with in-depth and expert knowledge on adipose stem cells, their developmental biologic origins, foundational research on ASC signaling mechanisms and immunomodulatory properties, and clinical insights into applications in regenerative medicine. Topics covered include basic adipose stem cell developmental biology and mechanisms of regulating self-renewal and activation in the stem cell niche, important methods for isolation and characterizing ASCs, and data on the impact on human demographics (age, sex, BMI) on ASC phenotype. A section devoted to ASC biology, ASCs for stem cell therapy and regenerative medicine, and ASCs in tissue engineering applications are also included. The book is written for scientists and clinicians who are broadly familiar with stem cells and basic cell biology principles and those seeking advanced information on adipose stem cells. - Coverage of basic adipose stem cell developmental biology (maturation process during embryogenesis) and mechanisms of regulating self-renewal and activation in the stem cell niche - Includes important methods for isolation and characterizing ASCs, as well as known data any impact of human demographics (age, sex, BMI) on ASC phenotype - An entire section dedicated to ASC biology, additional sections will be devoted to ASCs for stem cell therapy and regenerative medicine, as well as ASCs in tissue engineering applications

Now in a completely newly revised and expanded second edition, this comprehensive text presents the current state of the art in our understanding and management of polycystic ovary syndrome (PCOS), the most common hormonal disorder of reproductive aged women. The numerous bothersome symptoms of PCOS include menstrual irregularities, hirsutism, acne, scalp hair thinning, weigh excess and infertility; additionally, as they age, women with PCOS are at a higher risk for metabolic abnormalities such as diabetes and dyslipidemias, as well as for cardiovascular disease and even certain cancers. Despite improvements in our understanding of this condition, the exact cause/s of PCOS remain elusive; genetic, hormonal, metabolic and environmental underpinnings are all suggested as relevant. All chapters have been updated, with eight new chapters added across seven thematic sections. Part one discusses the epidemiology of PCOS in both adults and adolescents. Part two covers the pathophysiology of PCOS, including genetics, the hypothalamo-pituitary-ovarian and the hypothalamo-pituitary-adrenal axes, insulin resistance, inflammation, and obesity. The next three sections present the various management strategies, medical and surgical, for harnessing the symptomatology, including PCOS-related infertility; these chapters include added case material to provide real-world examples of the treatments in action and their efficacy. Part six covers the comorbidities that women with PCOS commonly encounter, such as issues of mental health, sleep disturbances, endometrial hyperplasia, and cancer, as well as examines the economic burden of PCOS. The final section discusses emerging concepts surrounding possible mechanisms and potential therapeutic approaches to PCOS, including angiogenic dysfunction, the role of vitamin D, future potential therapies to targeted AMH signaling. The closing chapter, by familiarizing the readers with the intergenerational implications ofPCOS and by raising awareness of potential “ripple effects”, aims at alerting the community on a need for vigilance as regards the health of PCOS progeny. With contributions from leaders in the field, Polycystic Ovary Syndrome, Second Edition remains the gold-standard text on this common medical condition and a valuable resource for the wide range of healthcare professionals engaged in caring for the women with PCOS (including but not limited to reproductive endocrinologists, gynecologists, family physicians, dermatologists, mental health professionals), for the aspiring women's health providers of tomorrow, and for the researchers who are striving to unravel the mysteries of the complex entity that PCOS is.

Sturkie's Avian Physiology, Seventh Edition is the classic comprehensive single volume on the physiology of domestic as well as wild birds. This latest edition is thoroughly revised and updated and features several new chapters with entirely new content on such topics as vision, sensory taste, pain reception, evolution, and domestication. Chapters throughout have been greatly expanded due to the many recent advances in the field. This book is written by international experts in different aspects of avian physiology. For easy reading and searches, this book is structured under a series of themes, beginning with genomic studies, sensory biology and nervous systems, and major organs. The chapters then move on to investigate metabolism, endocrine physiology, reproduction, and finally cross-cutting themes such as stress and rhythms. New chapters on feathers and skin are featured as well. Sturkie's Avian Physiology, Seventh Edition is an important resource for ornithologists, poultry scientists, and other researchers in avian studies. It is also useful for students in avian or poultry physiology, as well as avian veterinarians. - Stands out as the only single volume devoted to bird physiology - Features updates, revisions, or additions to each chapter - Written and edited by international leaders in avian studies