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This book provides comprehensive and in-depth explanations of all topics related to quantitative remote sensing and its applications in terrestrial, biospheric, hydrospheric, and atmospheric studies. It elucidates how to retrieve quantitative information on a wide range of environmental parameters from various remote sensing data at the highest accuracy possible and expounds how different aspects of the target of remote sensing can be quantified using diverse analytical methods and level of accuracy. Written in an easy-to-follow language, logically organized, and with step-by-step examples, the book assists readers to deepen their understanding of the theory and cutting-edge research on quantitative remote sensing. Features Explains how to retrieve quantitative information on a wide range of environmental parameters from various tailored remote sensing data at the highest accuracy possible. Manifests the author's decades of teaching and research in quantitative remote sensing and approaches the subject from both theoretical and pragmatic perspectives, informed by the latest research outcomes. Includes practical and real-life examples to illustrate how the quantitative information on a target can be retrieved from a given type of remote sensing data. Focuses on the latest developments in the field of quantitative remote sensing. Introduces sufficient mathematical concepts to reveal how remotely sensed data are converted to quantitative information while providing quality assurance of the retrieved results. This is a suitable textbook for upper-level undergraduate or postgraduate students and serves as a handy and valuable reference for professionals working in monitoring the environment. By reading this book, readers gain a sound understanding of how to retrieve quantitative information on the environment from diverse remote sensing data using the most appropriate cutting-edge methods and software.

This second edition delves into surface topography, exploring its impact on the functionality of various components. Beginning with an introduction to surface topography in Chapter 1, the subsequent chapters delve into the areal field parameters, feature parameters, filtering methods, and form removal techniques, leading into more specialized topics such as fractal-related multiscale geometric characterization and deep learning-based quantification of surface texture. With a focus on characterizing measurement data to glean functional insights, the book presents a comprehensive framework adopted by the international community. Through a diverse array of case studies spanning automotive applications, road surface engineering, additive manufacturing, and precision machining, readers are offered a holistic understanding of how areal techniques are pivotal in modern manufacturing industries. This edition builds upon the foundation laid by its predecessor, integrating evolving standards and additional case studies to provide an updated and comprehensive resource for modern surface engineering.

This edited book addresses the introduction to wheat, advancements in breeding, the contribution of biotechnological approaches, the development of climate-resilient wheat cultivars, and biofortification efforts to create nutrient-rich wheat cultivars.The world faces simultaneous challenges of a growing population and climate change. It is anticipated that the world population will exceed 9 billion by 2050. Meanwhile, climate change significantly impacts agriculture through uneven patterns, expected to worsen in the coming years, resulting in substantial losses due to biotic and abiotic stresses. Wheat, a staple food for millions worldwide, requires more studies to develop climate-resilient cultivars with improved nutritional content. Given these considerations, it is crucial to understand the activities conducted for wheat breeding and address the current gap to ensure an ample food supply for future generations.This book is beneficial for researchers, teachers, agriculturists, biologists, climate change scientists, and organizations involved in wheat breeding. It also serves as a valuable resource for undergraduate, master, and PhD students interested in wheat.

Estimates based on sequencing data suggest that there are around 5.1 million species of fungi. Yet only a small number of fungi are harmful to animals, including humans. In addition to host-pathogen interactions, there are also mutualistic interactions between fungi and animals. Diseases caused by pathogenic fungi range from allergic reactions and superficial infections to invasive mycoses, and have a significant impact on human and animal life. Fungi are also cultivated by animals as a food source in highly developed relationships or are even involved in gut mutualism. This 3rd edition of Volume 6 of The Mycota highlights exemplary interactions between fungal pathogens and their host(s). The book is organized in three parts: Part 1 summarizes our current understanding of important pathogenic fungi such as Candida species, Malassezia yeasts, Aspergillus fumigatus and fungi of the order Mucorales. Part 2 addresses the characterization of the host response towards pathogenic fungi. It focuses on RNA as a mediator of host-pathogen interactions, the human gut mycobiome, the role of the innate immune system in fighting infections, pattern recognition receptors involved in fungal infections, and a summary of established infection models for studying host-fungal-pathogen interactions. Part 3 provides insights into the impact transcriptomics and proteomics technologies have on the research of human-pathogenic fungi. The up-to-date reviews by experts in the field provide the reader with a comprehensive overview of the various research topics in the field of human and animal relationships with fungi and will hopefully help researchers to find inspiration for their own research.

This edited book is a compilation of the chapters on the recent advances made in the field of disease management in various field crops. It covers host resistance, regulatory mechanism as well as non-chemical methods and computer-based applications in disease management. Molecular marker assisted selection, proteomic approaches, CRISPR-Cas mediated technology to improve food quality and minimize negative public health impact associated with crop diseases is also discussed. Plant diseases continue to be major challenge to global crop production, especially field crops, inflicting not only crop yield losses to farmers, but also decline quality as well as nutritional value leading threat to global food security. According to FAO statistics, there is a need of 70% steady increase in agricultural production to fulfil the food requirements of 9.1 billion populations by 2050, and annual global crop losses due to pests and diseases have been estimated to be about 30%. Therefore, the book aims at bringing out a comprehensive information on field crop diseases, plant disease detection and diagnosis, monitoring, forecasting/forewarning, and management. The book is very useful for students, teachers, researchers, planners/administrators, and also the end users at national and international level.

This book provides clinicians with a comprehensive resource on the topic of respiratory complications of neuromuscular disease. It includes chapters by neurologists, pediatric pulmonologists, adult pulmonologists, anesthesiologists, and sleep physicians. The book begins with a review of the pathophysiology and epidemiology of the neuromuscular diseases that affect the respiratory system. It then includes chapters on pediatric concerns and the transition from pediatric providers to adult providers. There is additionally a focus on various therapeutic approaches and the monitoring of noninvasive ventilation. Finally, it includes a chapters on secretion clearance, palliative care and end of life decision making. The book appeals to a broad medical audience including adult pulmonologists, pediatric pulmonologists, respiratory therapists, nurses, sleep medicine providers, and neurologists.

This book is a comprehensive review of the recent research on the lipotoxicity-related mechanisms in obesity and the development of new treatment strategies. In this second edition, the possible molecular treatment methods and their recent clinical approaches are discussed in addition to the basic mechanisms that are available and thoroughly reviewed previously. Moreover, all chapters have been reviewed, according to the current concepts and seven new chapters are added, covering obesity-related epigenetic modifications, senescence, obesity-related cancer development, endocrine disruptors, as well as nanotechnology-based clinical approaches. This book is an essential resource for clinicians and basic science researchers, such as biochemists, toxicologists, immunologists, nutritionists, adult and pediatric endocrinologists, and cardiologists, as well as all researchers or students who want to learn the mysteries of obesity.

This volume focuses on alkaline metal-ion, redox flow, and metal sulfur batteries and provides details about the various kinds of advanced rechargeable batteries. It explains magnesium-ion batteries, sodium-ion batteries, metal sulfur batteries, and redox flow batteries with an introduction to rechargeable batteries and major upcoming batteries (magnesium-/sodium-ion batteries). Various kinds of redox flow batteries from introduction extending to the recent progress in redox flow batteries have been extensively discussed.Features: Covers recent battery technologies in detail, from chemistry to advances in post-lithium-ion batteries. Reviews magnesium-ion batteries, sodium-ion batteries, metal sulfur batteries, and redox flow batteries. Explains various metal sulfur batteries. Explores different types of redox flow batteries for large-scale energy storage application. Provides authoritative coverage of scientific contents via global contributing experts. This book is aimed at graduate students, researchers, and professionals in materials science, chemical and electrical engineering, and electrochemistry.

Opioids have played a prominent role in society for centuries and have been lauded for both their analgesic and euphoric qualities by cultures throughout the world. The advent of medical and pharmaceutical sciences in the 20th century ushered in a wide variety of different commercial opioid products that were designed to maximize their therapeutic potential. As the use of opioids increased, a corresponding need emerged to understand more about how opioids exert their effects in the body and brain; the consequences of opioid use regarding physical dependence, withdrawal, and craving; how we might best treat opioid use disorder (OUD) and address risk for opioid-related overdose; and how opioids may intersect with other clinical conditions to produce unique challenges. Edited by Kelly E. Dunn, The Oxford Handbook of Opioids and Opioid Use Disorder synthesizes research across the spectrum, and establishes a foundational knowledge regarding historical and current epidemiological trends, neurobiological and genetic contributors to opioid effects and OUD, and core elements of opioid use such as withdrawal and craving. It provides specific information and guidance regarding opioid treatment paradigms, including chapters on specific pharmacotherapies as well as treatment approaches, and discusses considerations for special clinical populations. An overview of these respective issues is provided across 38 chapters, which outline the history and science of these topics alongside clinical considerations and case examples. Written by expert bench scientists, epidemiologists, clinical trial interventionists, medical practitioners, and harm reduction specialists, this handbook will serve as a comprehensive guide for practitioners, policymakers, students, and researchers who wish to achieve a better understanding of the complex world of opioid and OUD practice and science.

This book has 32 chapters and approximately 950+ MCQs related to critical care medicine. Emphasis has been attributed to tropical diseases; infection control; neurocritical care; quality; patient safety; ethics; hemodynamic; and mechanical ventilation. The answers have been given for MCQs along with explanations and appropriate references at the end of every chapter. This book is highly interactive; and the content has been so designed as to cover the syllabus of critical care medicine training courses.

This book offers a comprehensive and timely review of planar microwave sensors based on coupled structures. Gathering chapters contributed by the most authoritative researchers on this topic, it presents various strategies for sensor performance optimization using coupled lines, directional couplers, and coupled resonators (either distributed or semi-lumped), focusing mainly on sensitivity optimization, and covering chains of coupled resonators as well. The book also reports on analytical methods, design formulas, sensor validation tests, with both simulation and experimental methods, describing some relevant practical applications. Mainly reflecting the research activity carried out by the different contributors in the last years, this book also includes two introductory chapters to help readers who are not very familiar with microwave sensing technologies and coupled structures. All in all, this book addresses advanced graduate students and researchers involved in microwave and sensor technologies, and may be of interest for engineers and professionals as well, working in areas as diverse as wireless sensors and sensor networks, biosensing, chemical sensing, motion control, microfluidics, Internet of Things (IoT), and smart systems.

This is an open access title available under the terms of a CC BY-NC-ND 4.0 International licence. It is free to read at Oxford Academic and offered as a free PDF download from OUP and selected open access locations. Jasper's Basic Mechanisms of the Epilepsies has served as the definitive reference in the field of basic research in the epilepsies for five decades through four well-regarded editions. Since its inception, the book has been an indispensable must-read and belongs in the hands of every experimental epilepsy investigator, practicing epileptologist, clinical neuroscientist, and student for both clinical and basic science reference, doctoral and board exam preparation. This fifth edition is the most ambitious yet and remains the definitive reference in the field, providing encyclopedic and updated coverage of the current understanding of basic research in the epilepsies, while also mapping new research directions for the next decade, and reviewing how molecular laboratory evidence is now being translated into new therapeutics. In 79 chapters, the book considers the role of interactions between neurons, synapses, and glia in the initiation, spread, and arrest of seizures. It examines mechanisms of excitability, synchronization, seizure susceptibility and, ultimately, their contributions to epileptogenesis. It provides a framework for expanding the monogenic epilepsy genome and understanding the complex heredity responsible for common epilepsies. It explores the molecular and cellular disease mechanisms of ion channelopathies, developmental epilepsy genes, and progressive myoclonic epilepsies. It considers newly emerging mechanisms of epilepsy comorbidities. And, for the first time, it describes current efforts to identify biomarkers of disease progression and translate discoveries of epilepsy disease mechanisms into new therapeutic strategies at the frontier of molecular medicine.

This book collects original peer-reviewed papers describing the latest developments in railway noise and vibration from the 14th International Workshop on Railway Noise (IWRN14), held on 7–9 December 2022, in Shanghai, China. It covers a broad range of railway noise and vibration topics, including high-speed rail and aerodynamic noise, wheel and rail noise, curving squeal noise, bridge noise, vehicle interior noise, structure-borne noise, and ground-borne vibration. Further topics such as resilient track forms, wheel out-of-round and polygonalization, rail roughness, corrugation and grinding, etc. are also covered. With the extensive and timely information offered, this book helps scientists and engineers in their daily efforts to identify, understand, and solve problems related to railway noise and vibration and to achieve the ultimate goal of minimizing the environmental impact of railway systems.

This comprehensive reference work presents an up-to-date survey of the current scientific understanding of the metabolic syndrome, as well as an overview of the most significant advances in the field. The book offers a thorough reference for obesity and the metabolic syndrome and will prove an indispensable resource for clinicians, researchers and students. The obesity epidemic has generated immense interest in recent years due to the wide-ranging and significant adverse health and economic consequences that surround the problem. Much attention has been focused on excessive consumption of energy-dense food, sedentary lifestyle, and other behaviors that contribute to the pathogenesis of obesity. However, obesity is a highly complex condition that is influenced by genetic as well as environmental factors. The metabolic syndrome comprises of central obesity, hyperglycemia, hypertension, and dsylipidemia. The incidence of metabolic syndrome is growing worldwide, affecting more than one-third of adults in some countries. The metabolic syndrome increases the risk of developing coronary artery disease and stroke, and it is closely associated with fatty liver, dementia, cancer, sleep apnea, kidney failure, and other diseases. This reference work covers the full range of scientific and clinical aspects of obesity and metabolic syndrome: epidemiology, genetics, environmental factors, pathophysiology, diseases associated with obesity, pediatric obesity, and clinical management.

Health Effects of Indoor Air Pollution, Volume Two, Air Pollution, Human Health, and the Environment is part of a three volume series. This volume covers the various classifications of indoor air pollutants and discusses the health impact of indoor pollutants, such as gaseous pollutants and particulate matter. It also examines epidemiological studies related to different air pollutants on health and the workplace. This book begins with an overview of classifications, sources, and occurrences of indoor air pollutants. It also examines the environmental and health impacts due to organic and inorganic air pollutants and how to mitigate them through exposure and risk management. Other sections explore'sick building syndrome,'which causes acute health and discomfort that appears to be linked to time spent in a building. Recent trends and control strategies for occupation exposure due to poor indoor air quality in industrial and nonindustrial workplaces to human health are also covered. This book is a valuable reference for academicians, researchers, and students in environmental health, public health, and occupational health, as well as environmental engineers, meteorologists, epidemiologists, medical researchers, and environmental toxicologists. - Reviews sources and occurrences of organic and inorganic air pollutants - Examines the health impact, such as'sick building syndrome,'and the effect of gaseous indoor pollutants and fine particulate matter on sensitive populations - Discusses indoor air quality and the link between ventilation, indoor air pollutants, and environmental quality

This book reviews recent advances in pancreatic endocrine and exocrine tissue development, function and regeneration. It provides a comprehensive overview on different aspects of beta-cell biology, including heterogeneity of function and gene expression and function, epigenetics, RNA and protein expression contributions to beta-cell specification and cell-fate maintenance. Furthermore, it covers recent progress in differentiating functional islets in vivo, environmental impacts on beta-cell development and function, and communications between various islet endocrine cells and how they contribute to the regulation of blood glucose homeostasis.The book provides a comprehensive resource for understanding the various compartments of the pancreas and is aimed at pancreas, beta-cell biology, and diabetes researchers.

This book provides the recent advanced research results of environmental engineering and energy resources, covering the main multidisciplinary research on waste treatment and recycling, ecological environment protection, energy strategy management, etc. The exploitation and extensive utilization of energy and resources result in negative impacts on the environment. Therefore, the use of energy and resources efficiently and eco-friendly has become an urgent research direction in environmental engineering. This book aims to promote scientific information exchange between scholars from universities, research centers, and high-tech enterprises around the world, which is beneficial to researchers and practitioners in the field of environmental engineering.

This book offers a comprehensive and authoritative review of bioactive substances found in plant underground stems, roots, rhizomes, corms, and tubers from all around the world. Tubers and starchy roots are plants that store edible starch content in underground stems, roots, rhizomes, corms, and tubers. They are a key source for both human and animal consumption and are rich in carbohydrates. They are widely used as industrial crops as well. Phytochemicals found in tubers and roots, such as phenolics, terpenoids, and alkaloids, have anti-inflammatory, anti-cancer, hypoglycemic, hypocholesterolemic, and antibacterial properties. Except for common potatoes, sweet potatoes, and cassava, the nutritional and health benefits of many tuberous crops have not yet been adequately investigated. This book sheds new insights into these topics by addressing several plant metabolites found in storage organs, which can be seen as scientifically neglected even though they have a high economic relevance as food and pharmaceutical sources. Divided into 6 parts, this book discusses how bioactive chemicals found in plant storage organs are synthesized and how their bioactive principles are specifically expressed in underground stems, roots, rhizomes, corms, and tubers. Additionally, each chapter includes background information on the plant, its parts, its nutritional makeup, chemical components, and biological functions. Given its breadth, the book appeals to a wide readership, from scholars through graduate and post-graduate students to professionals in the industry.

This book focuses on the subject area of Network Systems and Control Theory, providing a comprehensive examination of the dynamic behavior of networked systems operating under communication constraints. It introduces innovative iterative learning control strategies that aim to ensure stability, consistency, and security of networked systems. The field of networked systems has garnered significant interest from scientists and engineers across various disciplines, including information, electrical, transportation, life, social, and management sciences. This book consistently addresses a wide range of issues related to networked systems, emphasizing the critical impact of communication constraints on stability and security. It highlights the effectiveness and importance of iterative learning methods in tackling these challenges.Suitable for both undergraduate and graduate students interested in networked systems and iterative learning control, this book alsoserves as a valuable resource for university faculty and engineers engaged in complex systems, control theory research, and real-world applications. Its broad appeal extends to professionals working in related fields, seeking a deeper understanding of networked systems and their control mechanisms.

This book delves into the various aspects of the renin-angiotensin-aldosterone system (RAAS) and its role in cardiovascular disorders. It explores the use of anti-hypertensive agents, with a focus on (ACE) angiotensin-converting enzyme inhibitors and angiotensin receptor blockers (ARBs). The chapters cover topics such as the preferred use of ACE inhibitors over ARBs in high-risk patients, the impact of these agents on insulin resistance, their role in acute heart failure and peripheral artery disease, and their immunomodulatory activity in hypertensive patients. Additionally, the book examines the role of ACE inhibitors and ARBs in COVID-19 patients and provides insights into recent trends in managing hypertension through RAAS inhibition. It serves as a valuable resource for researchers, clinicians, and healthcare professionals involved in the field of cardiovascular medicine.

As global warming and climate change prevail, glaciers on our planet's highest peaks and polar, peri-polar, and sub-polar permafrost are melting. As this process unfolds, noxious greenhouse gases - such as methane and carbon dioxide - are released, as well as novel and ancient pathogens, from viruses to bacteria and other parasites. Our immune system is increasingly called to mount efficient defenses against these biological threats, and to attain new states of homeostatic balance by stressing certain immune cell populations, function, and cytokine profiles while depressing others. The physiological adaptation of the immune system to the demands of permafrost pathogens is discussed in this book as'permafrost immunity.'The point is made that permafrost immunity will concern every aspect of the immune system, from innate to adaptive immunity, from cellular to humoral immunity, and at the cellular level from T cell to B cell immunity. It is also argued in this book that because many of the most gravely threatening pathogens (e.g., influenza virus, corona virus, E. coli bacteria) penetrate the organism through the oral cavity, it is in the mouth that permafrost immunity may first become evident. In brief, this book on the topic of permafrost immunity, is written for professionals, clinicians and academicians, graduate students, and trainees in the health sciences, as well as the interested public. Its principal goal is to define and characterize the general scientific question of how prepared/unprepared our immune system is to counter the plethora of ancient and novel pathogens released by the melting permafrost.

This edited book support Sustainable Development Goal 2 (SDG 2): Zero Hunger. This book summarizes the contribution of genetic engineering for sustainable crop improvement toward global food and health security, climate resilience and economic growth. The book acts as a compendium of research reports on recent developments in the arena of cisgenics or transgenics or genome editing of crop plants for tolerance to biotic or abiotic stresses, introgression of value-added traits, molecular pharming etc. Sustainable crop productivity, yield and nutrition are the major constrain for food and nutritional security for the human population especially, in developing countries where arable land per capita is shrinking while the human population is steadily increasing. Zero hunger and achieving food security is the top priority of the United Nations development goals. This book explains various methods of genetic transformation such as transgenic, cisgenic, and genome editing for crop improvement. It also encompasses the advantages of genetic engineering in plants and their scope for sustainable crop improvement. The importance, limitations, challenges, GM biosafety regulations, recent advancements and future prospects of GM crops are covered in various chapters. This book is of interest to teachers, researchers, plant tissue culturists, GM crop experts, research scholars, academicians, plant breeders, policymakers etc. Also, the book serves as additional reading material for undergraduate and graduate students of agriculture, forestry, ecology, soil science, and environmental sciences. National and international agricultural scientists and policymakers will also find this to be a useful read.

Seismic Geology and Basin Analysis: Case Studies on Sedimentary Basins in China introduces the principles, approaches and techniques needed to solve problems using seismic data calibrated with well log, cores and outcrop profiles. The book emphasizes the adoption of seismic techniques into basin analysis and broadens the usage of seismic data in geological research which may be referred to as'seismic geology. The principle of the book is mainly summarized from a series of case studies in different basins in China. In addition, through this book readers can understand the primary characteristics and basin fill evolution of major petroleum basins around the world. When starting research on a basin, researchers and professionals are confronted with how to reveal the general architecture of basin fills and depict three-dimensional geometry, and the internal architecture of subsurface depositional bodies and their arrangement, hence this book is a great tome on necessary areas of exploration. - Examines the adoption of seismic techniques into basin analysis and broadens the usage of seismic data in geological research - Includes seismic, well log, core and outcrop data, as well as high resolution 3D seismic profiles and slices - Features case studies to further illustrate principles and approaches described in the book, which can be applied to similar basins around the world

This book explains various methods needed to overcome the challenges faced during environmental remediation with a focus on nanotechnology. The book comprises ten edited chapters that aim to inform and educate readers about recent technologies that are beneficial for pollution control.Starting with an introduction to environmental remediation, the book covers innovative nanomaterials including spinel nanoferrites, carbonaceous quantum dots, carbon nanotubes and nanobioadsorbents. In addition to highlighting the environmental benefits of these materials, the book includes chapters on the potential of nanotechnology for harnessing the environment to generate energy through nanogenerators and piezoelectric energy harvesting devices.Key features of the book include notes on fundamental issues and challenges regarding environmental remediation, easy to read content with pictorial illustrations and scholarly references for each chapter. The book is an informative resource for students and academicians in science, technology and environmental science discipline.

Environmental conditions and processes are one of the major pillars on which the human well-being rests. It is the core responsibility of the society to preserve and enhance better conditions for the human well-being. Indeed, there are several evolving unmet needs in public health. Emerging and re-emerging infectious diseases and a surge in the incidence of non-communicable diseases, including cardiovascular diseases (CAD), chronic respiratory diseases, and metabolic diseases have been impediments to sustainable well-being. Many factors are critical in the global surge in the rate and incidence of cardiovascular diseases. These include the shift from acute to chronic conditions, the shift from single risk factor vs. multiple influences, aging population, global health disparities, exposure to lower harmful influences over a longer period, etc. However, the epigenetic factors due to unhealthy environment play a most significant role in the underlying pathogenesis of cardiovascular diseases. Unfortunately, this has been ignored for a long time and realized lately to expand and disseminate knowledge to general population, expand research activities to investigate the cellular and molecular mechanisms, and develop better preventive and treatment strategies. The most significant environmental impoverishment in the pathogenesis of cardiovascular diseases include different genetical, chemical, physical, and biological influences, but not limited to, socio-economic status and lack of nutrients, nutritional aspects including habits, diets and additives, inhaled and ingested pollutants, exhaust gas and gasoline products, tobacco smoke, water pollution, alcohol consumption, soil and mineral pollution, solvents, pesticides, microplastics, non-critical usage of drugs, climate change, extreme atmospheric conditions, extremes in noise and temperature, electromagnetic influences, microwaves and radiation, outdoor light pollution, mental stressors, lack of or over exercise, microbiota and microbiological agents like SARS CoV-2 virus, etc.

Written and edited by world-renowned experts in the field, including Dr. Shoei K. Stephen Huang, a pioneer of radiofrequency catheter ablation procedures, Huang's Catheter Ablation of Cardiac Arrhythmias, 5th Edition, provides authoritative, comprehensive information on these increasingly used electrophysiology procedures. This outstanding resource is packed with cutting-edge content in every area of this fast-changing field, including anatomy, diagnostic criteria, differential diagnosis, mapping, and ablation. Ideal for practitioners who need a definitive, user-friendly ablation text for the electrophysiology lab or office setting, it offers quick access to practical content, using detailed tables and high-quality images to help you apply what you learn in your practice.Reflects all the latest technology, including the new pulse field ablation (PFA) procedure, new balloon technologies (RF, laser, and PFA) for pulmonary vein isolation, and high-resolution 3D mapping systems.Offers expert guidance on atrial tachycardia and flutter, atrial fibrillation, atrioventricular nodal reentrant tachycardia, tachycardias related to accessory atrioventricular connections, ventricular tachycardia, transseptal catheterization techniques, ablation for pediatric patients, and patient safety and complications.Contains new chapters covering Biophysics and Clinical Applications of Laser Ablation, Biophysics and Clinical Applications of Pulse Field Ablation, Multiple Strategic Approach to Ablate Atrial Fibrillation, Ablation of Challenging/Difficult Accessory Pathways, Ablation of Ventricular Tachycardia in Arrhythmogenic Ventricular Cardiomyopathy, and more.Contains 450 figures, including ECGs, intracardiac recordings, 3D mapping, ultrasound, fluoroscope, and ablation images.Includes numerous tables and boxes that provide quick access to key points, arrhythmia mechanisms, diagnostic criteria, target sites for ablation, use of special equipment, complications, and troubleshooting problems and their solutions.Provides access to 20 video clips, including transseptal access to the left atrium, intracardiac ultrasound, and techniques of pericardial access.Any additional digital ancillary content may publish up to 6 weeks following the publication date.

Treatise on Geochemistry, Third Edition, 8 volume set is an invaluable resource for geoscientists and others seeking to understand the origin, evolution, and functioning of our inhabited world, in service of a sustainable future.Our need to understand our planet is being reshaped by two ongoing scientific revolutions: the discovery of thousands of exoplanets and the advent of the Anthropocene. These seemingly disparate revolutions challenge us to deepen our understanding of Earth, as our best path to understanding how inhabited planets work. Geochemical knowledge and discovery are at the heart of this challenge, the crossroads where all geoscience subdisciplines meet – much as chemistry is often said to be the'central science', geochemistry is the'central geoscience'. Treatise on Geochemistry fills the gap between mature and established geochemical knowledge, including analytical developments and the rapidly evolving frontiers of the field. - Provides complete and comprehensive coverage of all aspects of the multi-disciplinary field of geochemistry - Restructured to streamline and consolidate topics and draw explicit connections to the twin revolutions of Astrobiology and the Anthropocene in each volume's introductory chapter - Updates to the new edition include new and expanded coverage of emerging topics like cosmochemistry, planetary geochemistry, and exoplanets - Follows a common template, making the work consistent and easier to navigate

This collection presents papers from the 153rd Annual Meeting & Exhibition of The Minerals, Metals & Materials Society.

This open access book about the sustainability of marine and terrestrial ecosystems in southern Africa provides a synthesis of the research program Science Partnerships for the Adaptation to Complex Earth System Processes (SPACES II, 2018-2022). It addresses the scientific, social, and economic issues related to climate change, its potential impacts on the various ecosystems, adaptations, and management interventions for enhancing systems resilience in Southern Africa. It is written by numerous scientists from African states and Germany and summarizes the latest research findings, which are of great relevance for a better understanding of climate change impacts, adaptations, and vulnerabilities as well as for developing management options and policy options to reduce the associated risks. This is crucial considering that the projected African population increase is exceptional. Furthermore, climate change is assumed to hit southern Africa extremely hard with a significant increase in extreme events and the frequency of severe droughts, heat waves, and flooding. Southern Africa hosts a high variety of ecosystems, which belongs to important biodiversity hotspots for unique flora and fauna. The surrounding oceans form, in turn, a bottle neck within the ocean's global thermohaline circulation, act as a still poorly understood carbon sink and source and play an important role for fisheries as they are highly productive. Considering these important aspects, the book is an important interdisciplinary contribution to the scientific literature and will find a wide readership.The book is aimed at students, teachers, and scientists in the fields of terrestrial and marine ecology, environmental, nature and landscape planning, agriculture, environmental and resource management, biodiversity, and nature conservation, as well as scientists and representatives in specialised authorities and associations, nature conservationists, and policy makers of related disciplines.

Intelligence-Based Cardiology and Cardiac Surgery: Artificial Intelligence and Human Cognition in Cardiovascular Medicine provides a comprehensive survey of artificial intelligence concepts and methodologies with real-life applications in cardiovascular medicine. Authored by a senior physician-data scientist, the book presents an intellectual and academic interface between the medical and data science domains. The book's content consists of basic concepts of artificial intelligence and human cognition applications in cardiology and cardiac surgery. This portfolio ranges from big data, machine and deep learning, cognitive computing and natural language processing in cardiac disease states such as heart failure, hypertension and pediatric heart care. The book narrows the knowledge and expertise chasm between the data scientists, cardiologists and cardiac surgeons, inspiring clinicians to embrace artificial intelligence methodologies, educate data scientists about the medical ecosystem, and create a transformational paradigm for healthcare and medicine. - Covers a wide range of relevant topics from real-world data, large language models, and supervised machine learning to deep reinforcement and federated learning - Presents artificial intelligence concepts and their applications in many areas in an easy-to-understand format accessible to clinicians and data scientists - Discusses using artificial intelligence and related technologies with cardiology and cardiac surgery in a myriad of venues and situations - Delineates the necessary elements for successfully implementing artificial intelligence in cardiovascular medicine for improved patient outcomes - Presents the regulatory, ethical, legal, and financial issues embedded in artificial intelligence applications in cardiology

This Volume 2 of a two-volume work provides an up-to-date overview of the latest advances in live biotherapeutics research, engineered and genome-edited probiotics. It focuses on key areas within probiotics and microbiome studies in human medicine, including their translation into commercial applications. The book is divided into three sections, comprising (I) biomedical and nutritional benefits of probiotics for human health, (II) post-genomic technologies in probiotics sciences and genome engineering, and (III) biosafety aspects and prospects of biotherapeutics. The broad spectrum of industry-relevant contributions makes this work a valuable resource for industry professionals as well as researchers in functional food and feed biotechnology, applied microbiology and gastroenterology. Presenting novel and evidence-based research, this volume will drive the commercial enterprise and meets the great demand for good probiotic products in the human medical sector.

This book is a compendium of the worldwide ocular stem cell, gene therapy, and other studies treating Optic Nerve Disease that are registered with Clinicaltrials.gov. The study and the Clinical Trial number is provided in order to make it easier for the reader to obtain further information. The book contains an introduction to Optic Nerve Disease as well as a summary of common optic nerve conditions. Clinical Trials in Optic Nerve Disease Treatment is a valuable resource for ophthalmologists, optometrists, other physicians, and researchers.

This book offers a comprehensive overview of atomically precise electrocatalysts, including single-atom, dual-atom, and multi-atom catalysts, which are considered to be superior electrode materials for fuel cells and water electrolyzers. By presenting a systematic examination of these materials in ascending order of metal atom number, the book provides a deep understanding of their synthesis processes, energy applications, and potential for improving their performance. Unlike any contemporary book on the topic, this book explores the reaction mechanisms and structure-performance relationships in catalytic processes at atomic level. Essentially, by driving the development of fuel cells and water electrocatalyzers, this book helps meet the world's growing energy demands. With its cutting-edge insights, this book is an indispensable resource for researchers, engineers, and students working in the field of renewable energy.

This book is built around ion channel research and, more specifically, ion channels as important therapeutic drug targets. Under the editorial leadership of Gary Stephens in academic research and Edward Stevens from industry, the aim is to bring these strands together to provide a cutting-edge translational reference on ion channel drug discovery. Exploiting our knowledge of ion channel structure and function has clear current and future potential to intervene and correct the pathophysiology associated with debilitating conditions, including cardiovascular disease, diabetes, cystic fibrosis, pain, epilepsy, and neurodegenerative disorders. Individual chapters have a disease focus, also providing a “case study story” that will also appeal to a clinical audience, while background information on a given ion channel is presented to provide a solid reference for undergraduate and postgraduate teaching.

Aerogels are ultralight porous materials showing great promise in environmental remediation and energy storage. Aerogels successfully remove pollutants and can improve the properties of batteries, supercapacitors and even flexible electronics. The book covers the fundamentals of hybrid aerogels synthesis and their applications. It includes computational approaches such as Molecular Dynamics, lattice Boltzmann method and Navier-Stokes solver.

This open access book focuses on cutting-edge research in high-performance concrete. Concrete has been a main construction material all over the world in the past century. As the demand for construction rises, the need for concrete with stronger performance grows as well. Existing studies on high-performance concrete are mainly on fiber admixtures and reactive mineral powder admixtures, with a focus on concrete proportioning and rheological properties. Through in-depth analysis of real-world engineering cases and demonstration of the latest research achievements, this book aims to provide a systematic review of research on high-performance concrete for civil engineers and scholars in related research fields. The topics of this book include but are not limited to the following: 1. Fiber Reinforced Concrete and Admixture Factors; 2. Effect of Mineral Reactive Powders on Concrete; 3. High Performance Concrete Packing Density and Rheological Properties; 4. High Performance Concrete Proportioning and Theoretical Research; 5. Research on Mechanical Properties of High Performance Concrete.

This proceedings book focuses on advances in theory, experiments and numerical simulations of fluid-structure-sound interactions related to turbulence, flow-induced vibration, noise and their control. This includes important practical areas of interaction such as vehicle aerodynamics, marine and civil engineering, nuclear reactors and biomedicine. One of the special features of this book is that it integrates new emerging fields with the study of fluid-structure-sound interactions, which is not common practice but scientifically very helpful in understanding, simulating and controlling fluid-structure-sound interaction systems. This provides a broader view of the discipline from which readers will benefit greatly.

This revised and expanded second edition provides a comprehensive and up-to-date overview of topics relating to head and neck and endocrine surgery, including: maxillofacial injuries, surgery of the scalp, surgery of the salivary glands, jaw tumors, surgery of the oral cavity (lips, tongue, floor of the mouth, and palate), swellings and ulcers of the face, inflammation in the neck, cervical lymphadenopathy, midline and lateral neck swellings, tumors of the pharynx, and endocrine surgery (thyroid gland, parathyroid glands, suprarenal glands, and neuroendocrine tumors). This second edition also includes additional and detailed chapters on thyroidectomy procedures, thyroid and parathyroid endocrine emergencies, thyroid and parathyroid disease during pregnancy, and thyroid and parathyroid transplantation. The coverage extends beyond surgical indications and procedures to encompass aspects such as anatomy, clinical presentation, and imaging diagnosis. With its clear structure, the book facilitates quick reference and will serve as a valuable tool for practitioners, as well as for upper-level graduate students.

Now in four convenient volumes, Field's Virology remains the most authoritative reference in this fast-changing field, providing definitive coverage of virology, including virus biology as well as replication and medical aspects of specific virus families.

This book comprehensively analyzes and summarizes the types, characteristics and prevention of deep-sea geological disasters in the South China Sea based on the research progress of global background. It also brings attention to the general public and stakeholders the risks of deep-sea geological disasters.

The 2nd International Conference of Mechanical System Dynamics (ICMSD2023) is devoted to “Technology Innovations by Understanding Mechanical Dynamics”, with 18 sessions to promote research in dynamic theories on complex structures, multidisciplinary integration, and advanced technologies for applications. It is held on September 1–5 in Peking University, Beijing, China. The conference is expected to provide a platform for academic researchers and engineers in the field of mechanical system dynamics to exchange scientific and technical ideas.

This book summarizes the recent advancements for biomaterials in the field of cardiovascular disease, including drug delivery system (gene, protein, drug), implant interventional instrument (heart valve, heart blocker, stent, artificial blood vessel, patch, artificial heart, cardiac pacemaker, etc.) have been innovated and applied to the clinical uses to treatment of cardiovascular disease. Through the summary of this book, readers will have comprehensive and advanced understanding of the application of biomaterials in the field of cardiovascular disease.

This book collects the selected papers of the XIV Congress of the International Association for Engineering Geology and the Environment held in Chengdu, Sichuan, China from September 21st - 27th, 2023, with the theme of Engineering Geology for a Habitable Earth. The meeting proceedings analyses the dynamic role of engineering geology in our changing world. The congress is expected to enhance the inter-disciplinary research development of international engineering geology and the environment, and contribute to the advancement of major projects, ecological progress, and habitable earth with in-depth discussion in the area of engineering geology and global climate change, geological hazard assessment and prevention, geotechnical properties of rock and soil mass, engineering geology and the environmental issues concerning marine, transportation, urban and ecological environment protection, engineering geology and resilience engineering construction, intelligent engineering geology, and new theories, methods, and techniques in engineering geology.

This book provides an excellent review and analysis of the latest information on rechargeable Li-S battery research. With a clear and concise writing style and in-depth technical material, this book will appeal to undergraduates and graduates, researchers, chemists, material scientists, and physicists working in the field of energy storage, especially those with an interest in Li-S battery technology. IEEE Electrical Insulation Magazine shows lithium-sulfur (Li-S) batteries give us an alternative to the more prevalent lithium-ion (Li-ion) versions and are known for their observed high-energy densities. Systems using Li-S batteries are in the early stages of development, and commercialization however could potentially provide higher, safer levels of energy at significantly lower cost. In this book, the history, scientific background, challenges, and future perspectives of the lithium-sulfur system are presented by experts in the field. Focus is on past and recent advances of each cell compartment responsible for the performance of the Li-S battery and includes analysis of characterization tools, new designs, and computational modeling. As a comprehensive review of the current state of play, it is ideal for undergraduates, graduate students, researchers, physicists, chemists, and materials scientists interested in energy storage, material science, and electrochemistry.

This book is about the'Mechanism and Genetic susceptibility of Neurological disorders. It is a comprehensive exploration, penned by esteemed authors, and offers a profound understanding of these enigmatic ailments, their progression, and the strategic approaches employed to mitigate their impact. In this book, readers will uncover a wealth of knowledge surrounding the mechanistic intricacies that underlie various neurological disorders. Through meticulous research and insightful analysis, the authors elucidate the inner workings of these conditions, shedding light on the mechanisms responsible for their onset and progression. The central themes of this book are the recognition of the genetic landscape governing neurological disorders. It emphasizes the role played by a diverse array of genes in the development and progression of these conditions, highlighting the multifaceted genetic susceptibility that underlies their manifestation. ​

This book provides diversified and comprehensive sedimentary, stratigraphic, and paleontological information services in China both for scientific research and educational purposes. Although China has the largest number of 11 “golden nails” profiles in the world, few of them has internationally renowned profiles with only traditional sedimentary methods and means for outcrops, logging, and seismic analysis. It combines multiple disciplines such as sedimentology, stratigraphy, paleontology, geophysics, geochemistry, and methods such as big data and artificial intelligence to build open-source online digital platform of geological profiles. Based on the preparation and construction of a number of well-known classic sections of sedimentary geology at home and abroad, it has become an important platform for training of sedimentology talents.

This book provides an overview of the drug discovery process from natural sources such as plants and microbes. While technological advances have streamlined the drug discovery process, enhancing the throughput and success rates, the structural features of natural products remain the primary reference for small-molecule drug discovery. Focusing on the drug targets blocked/altered by natural/nature-inspired molecules, it covers how potential drug leads are screened and identified using appropriate assay systems, and the current status of drugs identified using such approaches. State-of-the-art approaches in target identification, assay development, and lead identification have also been discussed in detail. Other topics included are targets and leads in inflammation, cancer, reproductive medicine, cardiovascular and neuromuscular ailments, and infectious diseases as well as the challenges in translating drug leads into clinically viable drugs. This volume serves as a handbook for researchers in phytochemistry and drug discovery, and as a reference for researchers and students of applied biology.

Cellular, Molecular and Environmental Contribution in Cardiac Remodeling: From Lab Bench to Clinical Perspective consolidates the most recent research advances on cellular, molecular, biochemical, and heterogeneous factors contributing to the physiological and pathological cardiac remodeling, elucidating their mechanisms of action and the clinical outcomes of cardiac remodeling. It extensively covers the factors determining cardiac remodeling, including cardiomyocyte regeneration, cardiac stem cells and their therapeutic potential, cardiac resident pericytes, the role of natural bioactive compounds in cardiac remodeling, chronic cardiac adaptations to exercise and more. This book provides basic science researchers and clinical investigators in cardiology with a current and comprehensive resource on molecular mechanisms and contributing factors to cardiac remodeling, and its effects and impacts on heart health. New research areas for the future, aimed at preventing, limiting, and reversing bad remodeling, are also discussed. - Provides a concise summary of recent developments in cardiac remodeling research, combining novel information and the latest data published in this field - Discusses not only cellular and molecular factors impacting cardiac remodeling, but also environmental contributions such as lifestyle and exercise - Identifies areas for future research and potential novel strategies for translating basic research knowledge to applications in patients

This book provides an overview of the new plant natural product skeletons discovered from 1999 to 2021. It categorizes these natural products by providing their names, source distributions, structural types, structure characteristics, and bioactivities. A total of 1373 plant products in 99 families are presented, which cover 36 different structure types within the Hypericaceae family of which the majority are alkaloid structures. In addition, it presents the biological profiling in the last 23 years by summarizing the biological activities and potential disadvantages. The new natural products skeleton presented are unprecedented structural scaffolds and could bring new opportunities for biological/pharmaceutical areas and provide new structure templates for synthetic chemists. This book helps readers gain in-depth insight into the past and recent trends of natural products; it also assists those interested in assessing the potential biological function of the natural products.

Extracorporeal membrane oxygenation (ECMO) is very quickly becoming a mainstream therapy for patients experiencing acute, severe, and often medically refractory cardiopulmonary failure. Over the years, the technology has improved and the guidelines, protocols, and indications for therapy have been refined. Similar to other'resource-intensive” technologies in which success or failure is often seen and experienced in the setting of a brief hospitalization, there is often much interest and intrigue when a patient is supported on ECMO. Success requires a team effort and a tremendous amount of hard work and effective communication. The hope is that this text will serve as a cornerstone for program growth and development as well as an inspiration for those intrigued by the potential benefits of ECMO.