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This volume aims at delivering the state-of-the-art scientific and clinical know-how for the management of patients with Connective Tissue Diseases (CTDs). With contributions from leading specialists from different disciplines, it presents the latest research findings on many aspects of the diseases in a clear, comprehensive way, and describes the most recent trends in treatment, such as the “treat to target” approach. Both basic science and clinical medicine are addressed, with emphasis on the most promising clinical and laboratory-based studies. The coverage is comprehensive in scope, and includes epidemiology, pathogenesis, autoantibodies and biomarkers, disease manifestations, involvement of different organs or systems, the relationships with other disorders, and biological therapy. Readers will find this second volume to be an excellent source of information on the current understanding of CTDs, and clinical approach to CTD, clearly conveying the progress made in recent years. Connective Tissue Disease – A Comprehensive Guide Vol.2 will be an invaluable source of up-to-date information for all practitioners involved in the care of patients with these complex diseases.

This book provides a contemporary panorama of advanced knowledge on the ureter. It covers basic knowledge and recent advances in a range of well-organized topics such as stone diagnosis, treatment, ureteroscopy, laser technology, reconstruction, oncology, trauma, embryology and radiology of the ureter. As shown in the table of contents, the book is written by a group of urology and non-urologic experts in their field and is enriched with many illustrations and summary tables. The 26 chapters are each dedicated to specific topics related to ureteral pathology and abnormality as well as diagnostic steps and treatment. Rare diseases that may affect the ureter are also included. Additionally there are basic educational materials that will be suitable for teaching, tutorials as well as electronic supplementary video clips and powerpoint presentations for demonstrations. The future perspectives of ureteral diseases, endoscopic and laparoscopic handling are covered. Fellows and medical professionals will find this a useful book with up-to-date knowledge of the various diseases and to demonstrate specific recent techniques involving stones, strictures and other pathologies of the ureter. Additional questions via app: Download the Springer Nature Flashcards app for free and use exclusive additional material to test your knowledge.

Asbestos: Risk Assessment, Epidemiology, and Health Effects offers a key text on the evolving information regarding asbestos and human health. Now in its third edition, this bestseller explores the pathological complexities of asbestos-related disease and examines how asbestos induces diseases in biological systems. The book also discusses the types of instruments and methods available for evaluation of the content of asbestiform minerals in products, air, water, surface areas, and tissue. It explains the relevance of each of these applications and gives readers the tools to evaluate data in the future.Edited by leading authorities on the subject and with contributions from a team of international experts, this book takes a cross-disciplinary approach and an authoritative review of the history, pathology, epidemiology, sampling, and analysis of asbestos. Backed up with photos and numerous diagrams, tables, and photographs, it features case studies, methodologies, and sampling/analytical schemes that put learning into context. Fully up-to-date and featuring four brand new chapters covering asbestosis and immunity, asbestos litigation and surgical and non-surgical management of mesothelioma, this book remains the most comprehensive source of information on asbestos and the only guide the reader will ever need to own.This essential text will appeal to any professional at any level who requires the latest expertise in dealing with asbestos. It suits researchers and practitioners alike, as well as those in the fields of law, health, education, hospitality, emergency response, building management and maintenance, construction, safety, insurance, and industrial hygiene.

Neuauflage in 3 Bänden: Standardwerk der Urologie für Klinik und PraxisDas in 3 Bänden gegliederte Standardwerk gilt als das umfassendste Nachschlage-Kompendium zum Fachbereich der Urologie. In Zusammenarbeit mit der Deutschen Gesellschaft für Urologie (DGU) und der Akademie der Deutschen Urologen haben die Experten aus Deutschland, Österreich und der Schweiz ein einzigartiges Buch für alle Urologen geschaffen.Die ganze Urologie in 3 Bändenvon der bildgebenden Diagnostik bis zur medikamentösen und operativen Therapieumfangreiche Ausstattung mit hervorragenden Zeichnungen, Fotos, Grafiken und Tabellen an den neuesten Leitlinien orientiertspezielle Tipps für Praxis und Klinikhervorragend didaktisch strukturiert: ideal zum Lernen für die FacharztprüfungZusammenfassung der wichtigsten Fakten eines Kapitels erleichtert die schnelle Informationsaufnahme, wenn die Zeit knapp istNeu in der 2. Auflagekomplett aktualisiert und erweitertneue Abbildungen und Grafikenneue Sektionen: Individuelle Tumortherapie, Geschlechtsinkongruenz, Prothetik, Laparoskopie, Geschichte der Urologie, Prinzipien der Bildgebung'Die Urologie': Ein Buch, an dem man als Urolog•in nicht vorbeikommt.

Micro-videos, a new form of user-generated contents, have been spreading widely across various social platforms, such as Vine, Kuaishou, and Tik Tok. Different from traditional long videos, micro-videos are usually recorded by smart mobile devices at any place within a few seconds. Due to its brevity and low bandwidth cost, micro-videos are gaining increasing user enthusiasm. The blossoming of micro-videos opens the door to the possibility of many promising applications, ranging from network content caching to online advertising. Thus, it is highly desirable to develop an effective scheme for the high-order micro-video understanding. Micro-video understanding is, however, non-trivial due to the following challenges: (1) how to represent micro-videos that only convey one or few high-level themes or concepts; (2) how to utilize the hierarchical structure of the venue categories to guide the micro-video analysis; (3) how to alleviate the influence of low-quality caused by complex surrounding environments and the camera shake; (4) how to model the multimodal sequential data, {i.e.}, textual, acoustic, visual, and social modalities, to enhance the micro-video understanding; and (5) how to construct large-scale benchmark datasets for the analysis? These challenges have been largely unexplored to date. In this book, we focus on addressing the challenges presented above by proposing some state-of-the-art multimodal learning theories. To demonstrate the effectiveness of these models, we apply them to three practical tasks of micro-video understanding: popularity prediction, venue category estimation, and micro-video routing. Particularly, we first build three large-scale real-world micro-video datasets for these practical tasks. We then present a multimodal transductive learning framework for micro-video popularity prediction. Furthermore, we introduce several multimodal cooperative learning approaches and a multimodal transfer learning scheme for micro-video venue category estimation. Meanwhile, we develop a multimodal sequential learning approach for micro-video recommendation. Finally, we conclude the book and figure out the future research directions in multimodal learning toward micro-video understanding.

This encyclopedia contains 22 volumes and a total of 552 chapters covering up-to-date research in the field of public health.

This new edition provides readers with a practice-based approach to all aspects of clinical nephrology. Extensively updated, it offers invaluable practical advice on how to manage specific illnesses and, uniquely, the importance of establishing systems and processes to improve patient safety, enhance the patient pathway and guidance on how to systematically improve clinical governance. A unique feature of this book are the tips and tricks and, suggestions for avoiding common errors based on the vast experience of the authors. In addition, the Editor has collated a list of links to international registries and guidelines as well as selected disease specific organisations, providing both clinicians and patients with access to helpful and recommended resources. Designed and written in a user-friendly fashion, Primer in Nephrology continues to be the definitive reference for practising nephrologists, trainees and non-nephrologist who encounter renal patients in their daily practice.

For humans, understanding a natural language sentence or discourse is so effortless that we hardly ever think about it. For machines, however, the task of interpreting natural language, especially grasping meaning beyond the literal content, has proven extremely difficult and requires a large amount of background knowledge. This book focuses on the interpretation of natural language with respect to specific domain knowledge captured in ontologies. The main contribution is an approach that puts ontologies at the center of the interpretation process. This means that ontologies not only provide a formalization of domain knowledge necessary for interpretation but also support and guide the construction of meaning representations. We start with an introduction to ontologies and demonstrate how linguistic information can be attached to them by means of the ontology lexicon model lemon. These lexica then serve as basis for the automatic generation of grammars, which we use to compositionally construct meaning representations that conform with the vocabulary of an underlying ontology. As a result, the level of representational granularity is not driven by language but by the semantic distinctions made in the underlying ontology and thus by distinctions that are relevant in the context of a particular domain. We highlight some of the challenges involved in the construction of ontology-based meaning representations, and show how ontologies can be exploited for ambiguity resolution and the interpretation of temporal expressions. Finally, we present a question answering system that combines all tools and techniques introduced throughout the book in a real-world application, and sketch how the presented approach can scale to larger, multi-domain scenarios in the context of the Semantic Web. Table of Contents: List of Figures / Preface / Acknowledgments / Introduction / Ontologies / Linguistic Formalisms / Ontology Lexica / Grammar Generation / Putting Everything Together / Ontological Reasoning for Ambiguity Resolution / Temporal Interpretation / Ontology-Based Interpretation for Question Answering / Conclusion / Bibliography / Authors'Biographies

Quantum Computing: From Alice to Bob provides a distinctive and accessible introduction to the rapidly growing fields of quantum information science and quantum computing. The textbook is designed for undergraduate students and upper-level secondary school students with little or no background in physics, computer science, or mathematics beyond secondary school algebra and a bit of trigonometry. Higher education faculty members and secondary school mathematics, physics, and computer science educators who want to learn about quantum computing and perhaps teach a course accessible to students with wide-ranging backgrounds will also find the book useful and enjoyable. While broadly accessible, the textbook also provides a solid conceptual and formal understanding of quantum states and entanglement - the key ingredients in quantum computing. The authors dish up a hearty meal for the readers, disentangling and explaining many of the classic quantum algorithms that demonstrate how and when QC has an advantage over classical computers. The book is spiced with Try Its, brief exercises that engage the readers in problem solving (both with and without mathematics) and help them digest the many counter-intuitive quantum information science and quantum computing concepts.

In this book, detailed information on the nosology, pathology, pathogenesis, clinical presentation, diagnosis and treatment of large- and medium-sized vessel and single-organ vasculitis is provided and critically discussed by the most expert physicians and researchers in the field. Among the conditions considered are giant cell arteritis, Takayasu arteritis, polyarteritis nodosa, primary central nervous system vasculitis, isolated aortitis, isolated gastrointestinal vasculitis, cutaneous vasculitis and isolated genitourinary vasculitis. The role of histopathology in the diagnosis and prognosis of these vasculitis is evaluated, along with the part played by imaging studies in diagnosing and monitoring these diseases, while indications and limitations of the available imaging modalities are discussed as well. The expanding role of biological agents for the treatment of the large vessel vasculitis is addressed, as well as the current approaches to these diseases. This book will be a valuable companion in decision-making for medical practitioners, internists, specialists, researchers and postgraduate students interested in the intriguing fields of vasculitis and rare diseases.

This book examines various aspects of the aorta, both healthy and diseased states, in 40 chapters of in-depth research by experts in cardiovascular disease. It begins with chapters on the embryology, anatomy, genetics, and physiology of the aorta along with imaging studies used to visualize its structure. The bulk of the book focuses on acute and chronic disorders such as coarctation of the aorta, inflammatory and connective tissue disorders, acute aortic thrombosis, infections, tumors, related ocular diseases, and various aneurysms and fistulas. In addition, it explores aortic disease in pregnancy, fetal aortic disorders, and aortic trauma in children. The book highlights the epidemiology and natural history as well as medical, endovascular, and surgical treatments for each disease. It also discusses valve repair, 3D printing applications, and the role of multidisciplinary aortic centers. Diseases of the Aorta is an indispensable and authoritative resource for cardiologists, cardiovascular surgeons, interventional radiologists, radiologists, and vascular medicine specialists.

Systemic and nervous system vasculitides are a heterogeneous group of related disorders, each characterized by vascular inflammation such that they have the potential to cause serious morbidity and mortality if unrecognized and therefore untreated. Systemic vasculitis affect all populations and every nationality and walk-of-life, from childhood to older age. The first edition of The Vasculitides, published in 2014, met the urgent need for a clear, concise, and reliable textbook regarding the epidemiology, pathogenesis, clinical presentation, laboratory evaluation and management of these disorders, assembling participants of the 16th International Vasculitis and ANCA Workshop in Paris, France. Five years later, two subsequent meetings have taken place in London and Tokyo. Participants of the 19th International Vasculitis and ANCA Workshop will gather in April 2019 at the University of Pennsylvania for an exceptional venue to share translational scientific discoveries, data from clinical trials, and advances in the clinical assessment, pathophysiology, genetic biomarkers, standard-of-care, and novel therapies of vasculitis. The Workshop participants regathered to update the The Vasculitides, producing an even more cutting-edge two-volume set of books. This is the first book in the set, covering general considerations and systemic vasculitis.

為政之道，講求利益本是無可厚非的。但是，美國人在對外關係是不是往往都把「美國利益」包裝成「美國價值」？美國人是不是可以講一套，做一套，而卻又面不改容？美國人是不是對同一性質之事，人家做便是十惡不赦，自己做時卻是天經地義？ 常言道，外交活動的根本目的，是追求國家利益，亦有謂國與國之間只有永恆的利益，沒有永恆的敵人或朋友。但是，自稱與眾不同的美國自詡推動人權外交，宣稱要把民主、自由、人權和法治帶到全世界。正所謂聽其言而觀其行。從美國近百多年來的行為可見，美國外交的目標是要控制世界各地的市場和資源。所以，只要某個國家的政府是親美的，不論其是否獨裁專制，美國都會支持，但如果某個國家的政府是反美的，則就算是民主選舉產生的，美國也會設法把其推翻。 這幾十年來，美國打著民主的旗號來針對反美的國家或地區的政府，透過所謂「非政府組織」（尤其是「國家民主基金會」）扶植及培養當地的反對政治勢力，以民主、自由和人權之名，行搶奪政權之實。

The easiest way to learn Lua programmingKey FeaturesThe easiest way to learn Lua codingUse the Lua standard libraries and debug Lua codeEmbed Lua as a scripting language using the Lua C APIBook DescriptionLua is a small, powerful and extendable scripting/programming language that can be used for learning to program, and writing games and applications, or as an embedded scripting language. There are many popular commercial projects that allow you to modify or extend them through Lua scripting, and this book will get you ready for that. This book is the easiest way to learn Lua. It introduces you to the basics of Lua and helps you to understand the problems it solves. You will work with the basic language features, the libraries Lua provides, and powerful topics such as object-oriented programming. Every aspect of programming in Lua, variables, data types, functions, tables, arrays and objects, is covered in sufficient detail for you to get started. You will also find out about Lua's module system and how to interface with the operating system. After reading this book, you will be ready to use Lua as a programming language to write code that can interface with the operating system, automate tasks, make playable games, and much more. This book is a solid starting point for those who want to learn Lua in order to move onto other technologies such as Love2D or Roblox. A quick start guide is a focused, shorter title that provides a faster paced introduction to a technology. It is designed for people who don't need all the details at this point in their learning curve. This presentation has been streamlined to concentrate on the things you really need to know. What you will learnUnderstand the basics of programming the Lua languageUnderstand how to use tables, the data structure that makes Lua so powerfulUnderstand object-oriented programming in Lua using metatablesUnderstand standard LUA libraries for math, file io, and moreManipulate string data using LuaUnderstand how to debug Lua applications quickly and effcientlyUnderstand how to embed Lua into applications with the Lua C APIWho this book is forThis book is for developers who want to get up and running with Lua. This book is ideal for programmers who want to learn to embed Lua in their own applications, as well as for beginner programmers who have never coded before.

Work with Python and powerful open source tools such as Gensim and spaCy to perform modern text analysis, natural language processing, and computational linguistics algorithms.Key FeaturesDiscover the open source Python text analysis ecosystem, using spaCy, Gensim, scikit-learn, and KerasHands-on text analysis with Python, featuring natural language processing and computational linguistics algorithmsLearn deep learning techniques for text analysisBook DescriptionModern text analysis is now very accessible using Python and open source tools, so discover how you can now perform modern text analysis in this era of textual data. This book shows you how to use natural language processing, and computational linguistics algorithms, to make inferences and gain insights about data you have. These algorithms are based on statistical machine learning and artificial intelligence techniques. The tools to work with these algorithms are available to you right now - with Python, and tools like Gensim and spaCy. You'll start by learning about data cleaning, and then how to perform computational linguistics from first concepts. You're then ready to explore the more sophisticated areas of statistical NLP and deep learning using Python, with realistic language and text samples. You'll learn to tag, parse, and model text using the best tools. You'll gain hands-on knowledge of the best frameworks to use, and you'll know when to choose a tool like Gensim for topic models, and when to work with Keras for deep learning. This book balances theory and practical hands-on examples, so you can learn about and conduct your own natural language processing projects and computational linguistics. You'll discover the rich ecosystem of Python tools you have available to conduct NLP - and enter the interesting world of modern text analysis.What you will learnWhy text analysis is important in our modern ageUnderstand NLP terminology and get to know the Python tools and datasetsLearn how to pre-process and clean textual dataConvert textual data into vector space representationsUsing spaCy to process textTrain your own NLP models for computational linguisticsUse statistical learning and Topic Modeling algorithms for text, using Gensim and scikit-learnEmploy deep learning techniques for text analysis using KerasWho this book is forThis book is for you if you want to dive in, hands-first, into the interesting world of text analysis and NLP, and you're ready to work with the rich Python ecosystem of tools and datasets waiting for you!

Make the most of Kotlin by leveraging design patterns and best practices to build scalable and high performing appsKey Features[•] Understand traditional GOF design patterns to apply generic solutions[•] Shift from OOP to FP; covering reactive and concurrent patterns in a step-by-step manner[•] Choose the best microservices architecture and MVC for your development environmentBook DescriptionDesign patterns enable you as a developer to speed up the development process by providing you with proven development paradigms. Reusing design patterns helps prevent complex issues that can cause major problems, improves your code base, promotes code reuse, and makes an architecture more robust. The mission of this book is to ease the adoption of design patterns in Kotlin and provide good practices for programmers. The book begins by showing you the practical aspects of smarter coding in Kotlin, explaining the basic Kotlin syntax and the impact of design patterns. From there, the book provides an in-depth explanation of the classical design patterns of creational, structural, and behavioral families, before heading into functional programming. It then takes you through reactive and concurrent patterns, teaching you about using streams, threads, and coroutines to write better code along the way By the end of the book, you will be able to efficiently address common problems faced while developing applications and be comfortable working on scalable and maintainable projects of any size. What you will learnGet to grips with Kotlin principles, including its strengths and weaknessesUnderstand classical design patterns in KotlinExplore functional programming using built-in features of KotlinSolve real-world problems using reactive and concurrent design patternsUse threads and coroutines to simplify concurrent code flowUnderstand antipatterns to write clean Kotlin code, avoiding common pitfallsLearn about the design considerations necessary while choosing between architecturesWho this book is forThis book is for developers who would like to master design patterns with Kotlin to build efficient and scalable applications. Basic Java or Kotlin programming knowledge is assumed

Developing expert level application development skills with C++ Key Features - ​Take ​ ​advantage ​ ​of ​ ​the ​ ​myriad ​ ​of ​ ​features ​ ​and ​ ​possibilities ​ ​that ​ ​C++ offers ​ ​to ​ ​build ​ real-world ​ ​applications - Delve into the fundamentals of multithreading and concurrency and find out how to implement them - Learn the latest features of C++ and how to write better code by using the Standard Library Book Description C++ has ​ ​come ​ ​a ​ ​long ​ ​way ​ ​and ​ ​has ​ ​now ​ ​been ​ ​adopted ​ ​in ​ ​several ​ ​contexts. Its ​ ​key ​strengths ​ ​are ​ ​its ​ ​software ​ ​infrastructure ​ ​and ​ ​resource-constrained applications. ​ ​The ​C++ ​ ​17 ​ ​release ​ ​will ​ ​change ​ ​the ​ ​way ​ ​developers ​ ​write code, ​ ​and ​ ​this ​ ​course ​ ​will ​ ​help ​you ​ ​master ​ ​your ​ ​developing ​ ​skills ​ ​with ​ ​C++. With ​ ​real-world, ​ ​practical ​ ​examples ​ ​explaining ​ ​each ​ ​concept, ​ ​the ​ ​course is divided into three modules where ​ ​will begin ​ ​by ​ ​introducing ​ ​you ​ ​to ​ ​the ​ ​latest ​ ​features ​ ​in ​ ​C++ ​ ​17. ​ ​It ​ ​encourages clean ​code ​ ​practices ​ ​in ​ ​C++ ​ ​in ​ ​general ​ ​and ​ ​demonstrates ​ ​the ​ ​GUI app-development ​ ​options ​ ​in ​ ​C++. ​ ​You'll ​ ​get ​ ​tips ​ ​on ​ ​avoiding ​ ​memory ​ ​leaks using ​ ​smart-pointers. ​ In the next module, ​ ​you'll ​ ​see ​ ​how ​ ​multi-threaded ​programming can ​ ​help ​ ​you ​ ​achieve ​ ​concurrency ​ ​in ​ ​your ​ ​applications. We start with a brief introduction to the fundamentals of multithreading and concurrency concepts. We then take an in-depth look at how these concepts work at the hardware-level as well as how both operating systems and frameworks use these low-level functions. You will learn about the native multithreading and concurrency support available in C++ since the 2011 revision, synchronization and communication between threads, debugging concurrent C++ applications, and the best programming practices in C++. Moving ​ ​on, ​ ​you'll ​ ​get ​ ​an ​ ​in-depth ​ ​understanding ​ ​of ​ ​the ​ ​C++ ​ ​Standard Template ​ ​Library. ​Where we show implementation-specific, problem-solution approach that will help you quickly overcome hurdles. You will learn the core STL concepts, such as containers, algorithms, utility classes, lambda expressions, iterators, and more while working on practical real-world recipes. These recipes will help you get the most from the STL and show you how to program in a better way. Jeganathan Swaminathan : Mastering C++ Programming Maya Posch : Mastering C++ Multithreading Jacek Galowicz : C++17 STL Cookbook What you will learn ​Write ​ ​modular ​ ​C++ ​ ​applications ​ ​in ​ ​terms ​ ​of ​ ​the ​ ​existing ​ ​and newly ​ ​introduced ​ ​features ​ ​Identify ​ ​code-smells, ​ ​clean ​ ​up, ​ ​and ​ ​refactor ​ ​legacy ​ ​C++ applications ​ ​Leverage ​ ​the ​ ​possibilities ​ ​provided ​ ​by ​ ​Cucumber ​ ​and ​ ​Google Test/Mock ​ ​to automate ​ ​test ​ ​cases Deep dive into the details of the how various operating systems currently implement multithreading Choose the best multithreading APIs when designing a new application Explore the use of mutexes, spin-locks, and other synchronization concepts and see how to safely pass data between threads Work with strings the STL way instead of handcrafting C-style code Understand standard support classes for concurrency and synchronization, and how to put them to work Use the filesystem library addition available with the C++17 STL Who this book is for This ​course ​is​ ​for​ ​intermediate to advanced level​ ​C++ ​developers who want to get the most out of C++ to build concurrent and scalable application.Jeganathan Swaminathan, Jegan for short, is

Your one-stop guide to using Python, creating your own hacking tools, and making the most out of resources available for this programming languageKey FeaturesComprehensive information on building a web application penetration testing framework using PythonMaster web application penetration testing using the multi-paradigm programming language PythonDetect vulnerabilities in a system or application by writing your own Python scriptsBook DescriptionPython is an easy-to-learn and cross-platform programming language that has unlimited third-party libraries. Plenty of open source hacking tools are written in Python, which can be easily integrated within your script. This book is packed with step-by-step instructions and working examples to make you a skilled penetration tester. It is divided into clear bite-sized chunks, so you can learn at your own pace and focus on the areas of most interest to you. This book will teach you how to code a reverse shell and build an anonymous shell. You will also learn how to hack passwords and perform a privilege escalation on Windows with practical examples. You will set up your own virtual hacking environment in VirtualBox, which will help you run multiple operating systems for your testing environment. By the end of this book, you will have learned how to code your own scripts and mastered ethical hacking from scratch.What you will learnCode your own reverse shell (TCP and HTTP)Create your own anonymous shell by interacting with Twitter, Google Forms, and SourceForgeReplicate Metasploit features and build an advanced shellHack passwords using multiple techniques (API hooking, keyloggers, and clipboard hijacking)Exfiltrate data from your targetAdd encryption (AES, RSA, and XOR) to your shell to learn how cryptography is being abused by malwareDiscover privilege escalation on Windows with practical examplesCountermeasures against most attacksWho this book is forThis book is for ethical hackers; penetration testers; students preparing for OSCP, OSCE, GPEN, GXPN, and CEH; information security professionals; cybersecurity consultants; system and network security administrators; and programmers who are keen on learning all about penetration testing.

React 16 Tooling covers the most important tools, utilities, and libraries that every React developer needs to know — in detail.Key FeaturesEach chapter presents meta-development solutions to help React developersThe tools used are presented in a practical, solution-oriented approach with no fluffThe chapters are arranged in a logical order that mirrors a typical React development workflow, but you are free to tweak the approaches discussed to fit your own unique styleBook DescriptionReact 16 Tooling covers the most important tools, utilities, and libraries that every React developer needs to know — in detail. As React has grown, the amazing toolset around it has also grown, adding features and enhancing the development workflow. Each of these essential tools is presented in a practical manner and in a logical order mirroring the development workflow. These tools will make your development life simpler and happier, enabling you to create better and more performant apps. Adam starts with a hand-picked selection of the best tools for the React 16 ecosystem. For starters, there's the create-react-app utility that's officially supported by the React team. Not only does this tool bootstrap your React project for you, it also provides a consistent and stable framework to build upon. The premise is that when you don't have to think about meta development work, more focus goes into the product itself. Other React tools follow this same approach to automating and improving your development life. Jest makes unit testing quicker. Flow makes catching errors easier. Docker containers make deployment in a stack simpler. Storybook makes developing components straightforward. ESLint makes writing standardized code faster. The React DevTools plugin makes debugging a cinch. React 16 Tooling clears away the barriers so you can focus on developing the good parts. In this book, we'll look at each of these powerful tools in detail, showing you how to build the perfect React ecosystem to develop your apps within. What you will learnBootstrap a React application using create-react-appIsolate React component development using StorybookWrite effective unit tests for your React components using JestEnsure that your component code is to standard using ESLintUse browser extensions and built-in component instrumentation to debug React applicationsEnable type safety in React components with FlowtypeDeploy React applications inside a Docker container as part of a larger application stackWho this book is forThis book is for React developers of any skill level who want to make their lives easier. It helps to have some familiarity with React, but if you are an experienced web developer looking at React, then this book will show you how to build a resilient toolset around you before you begin.

A tutorial leading the aspiring Go developer to full mastery of Golang s distributed features.Key Features[•] This book provides enough concurrency theory to give you a contextual understanding of Go concurrency[•] It gives weight to synchronous and asynchronous data streams in Golang web applications[•] It makes Goroutines and Channels completely familiar and natural to Go developersBook DescriptionDistributed Computing with Go gives developers with a good idea how basic Go development works the tools to fulfill the true potential of Golang development in a world of concurrent web and cloud applications. Nikhil starts out by setting up a professional Go development environment. Then you'll learn the basic concepts and practices of Golang concurrent and parallel development. You'll find out in the new few chapters how to balance resources and data with REST and standard web approaches while keeping concurrency in mind. Most Go applications these days will run in a data center or on the cloud, which is a condition upon which the next chapter depends. There, you'll expand your skills considerably by writing a distributed document indexing system during the next two chapters. This system has to balance a large corpus of documents with considerable analytical demands. Another use case is the way in which a web application written in Go can be consciously redesigned to take distributed features into account. The chapter is rather interesting for Go developers who have to migrate existing Go applications to computationally and memory-intensive environments. The final chapter relates to the rather onerous task of testing parallel and distributed applications, something that is not usually taught in standard computer science curricula.What you will learnGain proficiency with concurrency and parallelism in GoLearn how to test your application using Go s standard libraryLearn industry best practices with technologies such as REST, OpenAPI, Docker, and so onDesign and build a distributed search engineLearn strategies on how to design a system for web scaleWho this book is forThis book is for developers who are familiar with the Golang syntax and have a good idea of how basic Go development works. It would be advantageous if you have been through a web application product cycle, although it's not necessary.

Over-fetching and under-fetching data can negatively impact the performance of your web application. Future-proof your API structure and handle key development requirements by correctly defining types and schemas in GraphQL. Key FeaturesIncludes server-side implementations using GraphQL.js, Apollo, Graphcool, and PrismaUnderstand an example client-side implementation of GraphQL in ReactJS using ApolloImplement over 20 practical activities and exercises across 5 topics that enable you to efficiently use GraphQL in production Book Description Though fairly new, GraphQL is quickly rising in popularity when it comes to API development. This book will teach you everything you need to know to start building efficient APIs with GraphQL. You'll begin by learning to create a simple scaffold application using Node.js and Express. Then, you'll explore core GraphQL concepts and study how GraphQL integrates with other frameworks in real-life business applications. By the end of the book, you will be able to successfully create efficient client-server REST-like applications. What you will learnUnderstand core GraphQL concepts that can be used across different languagesUnderstand the overall structure of GraphQL applicationsUse Apollo GraphQL for both server and client JavaScript applicationsUnderstand the key differences between GraphQL and RESTWho this book is for This book is ideal for developers who want to broaden their understanding of API development. Prior experience to JavaScript is required, with any prior work with React or Node.js being beneficial. Brian Kimokoti is a software developer with Andela. He holds a bachelor's degree in computer science from the Multimedia University of Kenya. For the last 5 years, he has been developing applications in PHP, JavaScript, and Python. Brian is a regular tech blogger on different online platforms and aspires to gain more experience and skills to an engineering and architect level.

Discover how to use the next-generation language Red for full-stack development, from systems coding over user-interfaces to blockchain programmingKey FeaturesExplore the latest features of Red to build scalable, fast, and secure applicationsLearn graphical programming and build highly sophisticated reactive applicationsGet familiar with the specific concepts and techniques of Red development, like working with series, viewing code as data, and using dialects.Book DescriptionA key problem of software development today is software bloat, where huge toolchains and development environments are needed in software coding and deployment. Red significantly reduces this bloat by offering a minimalist but complete toolchain. This is the first introductory book about it, and it will get you up and running with Red as quickly as possible. This book shows you how to write effective functions, reduce code redundancies, and improve code reuse. It will be helpful for new programmers who are starting out with Red to explore its wide and ever-growing package ecosystem and also for experienced developers who want to add Red to their skill set. The book presents the fundamentals of programming in Red and in-depth informative examples using a step-by-step approach. You will be taken through concepts and examples such as doing simple metaprogramming, functions, collections, GUI applications, and more. By the end of the book, you will be fully equipped to start your own projects in Red.What you will learnSet up your Red environment to achieve the highest productivityGet grounded in Red, gaining experience and insight through many examples and exercisesBuild simple, compact, and portable applicationsAnalyze streams of data through ParseCompose GUI applications with View and DrawGet prepared for smart contract blockchain programming in RedWho this book is forThis book is for software developers and architects who want to learn Red because of its conciseness, flexibility, and expressiveness, and more specifically for its possibilities in GUI apps and blockchain / smart contracts programming. Some knowledge of the basic concepts and experience of any programming language is assumed.

Leverage the power of Tensorflow to design deep learning systems for a variety of real-world scenariosKey Features[•]Build efficient deep learning pipelines using the popular Tensorflow framework[•]Train neural networks such as ConvNets, generative models, and LSTMs[•]Includes projects related to Computer Vision, stock prediction, chatbots and moreBook DescriptionTensorFlow is one of the most popular frameworks used for machine learning and, more recently, deep learning. It provides a fast and efficient framework for training different kinds of deep learning models, with very high accuracy. This book is your guide to master deep learning with TensorFlow with the help of 10 real-world projects. TensorFlow Deep Learning Projects starts with setting up the right TensorFlow environment for deep learning. You'll learn how to train different types of deep learning models using TensorFlow, including Convolutional Neural Networks, Recurrent Neural Networks, LSTMs, and Generative Adversarial Networks. While doing this, you will build end-to-end deep learning solutions to tackle different real-world problems in image processing, recommendation systems, stock prediction, and building chatbots, to name a few. You will also develop systems that perform machine translation and use reinforcement learning techniques to play games. By the end of this book, you will have mastered all the concepts of deep learning and their implementation with TensorFlow, and will be able to build and train your own deep learning models with TensorFlow confidently.What you will learnSet up the TensorFlow environment for deep learningConstruct your own ConvNets for effective image processingUse LSTMs for image caption generationForecast stock prediction accurately with an LSTM architectureLearn what semantic matching is by detecting duplicate Quora questionsSet up an AWS instance with TensorFlow to train GANsTrain and set up a chatbot to understand and interpret human inputBuild an AI capable of playing a video game by itself –and win it!Who this book is forThis book is for data scientists, machine learning developers as well as deep learning practitioners, who want to build interesting deep learning projects that leverage the power of Tensorflow. Some understanding of machine learning and deep learning, and familiarity with the TensorFlow framework is all you need to get started with this book.

Excerpt from Saint Bruno Et l'Ordre des Chartreux, Vol. 2 (Classic Reprint)

Key Features[•] Learn and improve the sequential performance characteristics of your software[•] Understand the use of operating system processes in a high-scale concurrent system[•] Learn of the various coordination methods available in the Standard libraryBook DescriptionMost programming languages can really complicate things, especially with regard to unsafe memory access. The burden on you, the programmer, lies across two domains: understanding the modern machine and your language's pain-points. This book will teach you to how to manage program performance on modern machines and build fast, memory-safe, and concurrent software in Rust. It starts with the fundamentals of Rust and discusses machine architecture concepts. You will be taken through ways to measure and improve the performance of Rust code systematically and how to write collections with confidence. You will learn about the Sync and Send traits applied to threads, and coordinate thread execution with locks, atomic primitives, data-parallelism, and more. The book will show you how to efficiently embed Rust in C++ code and explore the functionalities of various crates for multithreaded applications. It explores implementations in depth. You will know how a mutex works and build several yourself. You will master radically different approaches that exist in the ecosystem for structuring and managing high-scale systems. By the end of the book, you will feel comfortable with designing safe, consistent, parallel, and high-performance applications in Rust.What you will learnProbe your programs for performance and accuracy issuesCreate your own threading and multi-processing environment in RustUse coarse locks from Rust's Standard librarySolve common synchronization problems or avoid synchronization using atomic programmingBuild lock-free/wait-free structures in Rust and understand their implementations in the crates ecosystemLeverage Rust's memory model and type system to build safety properties into your parallel programsUnderstand the new features of the Rust programming language to ease the writing of parallel programsWho this book is forThis book is aimed at software engineers with a basic understanding of Rust who want to exploit the parallel and concurrent nature of modern computing environments, safely.

A definitive guide to creating an intelligent web application with the best of machine learning and JavaScriptKey FeaturesSolve complex computational problems in browser with JavaScriptTeach your browser how to learn from rules using the power of machine learningUnderstand discoveries on web interface and API in machine learningBook DescriptionIn over 20 years of existence, JavaScript has been pushing beyond the boundaries of web evolution with proven existence on servers, embedded devices, Smart TVs, IoT, Smart Cars, and more. Today, with the added advantage of machine learning research and support for JS libraries, JavaScript makes your browsers smarter than ever with the ability to learn patterns and reproduce them to become a part of innovative products and applications. Hands-on Machine Learning with JavaScript presents various avenues of machine learning in a practical and objective way, and helps implement them using the JavaScript language. Predicting behaviors, analyzing feelings, grouping data, and building neural models are some of the skills you will build from this book. You will learn how to train your machine learning models and work with different kinds of data. During this journey, you will come across use cases such as face detection, spam filtering, recommendation systems, character recognition, and more. Moreover, you will learn how to work with deep neural networks and guide your applications to gain insights from data. By the end of this book, you'll have gained hands-on knowledge on evaluating and implementing the right model, along with choosing from different JS libraries, such as NaturalNode, brain, harthur, classifier, and many more to design smarter applications. What you will learnGet an overview of state-of-the-art machine learningUnderstand the pre-processing of data handling, cleaning, and preparationLearn Mining and Pattern Extraction with JavaScriptBuild your own model for classification, clustering, and predictionIdentify the most appropriate model for each type of problemApply machine learning techniques to real-world applicationsLearn how JavaScript can be a powerful language for machine learningWho this book is forThis book is for you if you are a JavaScript developer who wants to implement machine learning to make applications smarter, gain insightful information from the data, and enter the field of machine learning without switching to another language. Working knowledge of JavaScript language is expected to get the most out of the book.

Learn how to build high-performing enterprise applications using Java EE powered by Angular at the frontendKey Features[•] Leverage Java EE 8 features to build robust backend for your enterprise applications[•] Use Angular to build a single page frontend and combine it with the Java EE backend[•] A practical guide filled with ample real-world examplesBook DescriptionThe demand for modern and high performing web enterprise applications is growing rapidly. No more is a basic HTML frontend enough to meet customer demands. This book will be your one-stop guide to build outstanding enterprise web applications with Java EE and Angular. It will teach you how to harness the power of Java EE to build sturdy backends while applying Angular on the frontend. Your journey to building modern web enterprise applications starts here! The book starts with a brief introduction to the fundamentals of Java EE and all the new APIs offered in the latest release. Armed with the knowledge of Java EE 8, you will go over what it's like to build an end-to-end application, configure database connection for JPA, and build scalable microservices using RESTful APIs running in Docker containers. Taking advantage of the Payara Micro capabilities, you will build an Issue Management System, which will have various features exposed as services using the Java EE backend. With a detailed coverage of Angular fundamentals, the book will expand the Issue Management System by building a modern single page application frontend. Moving forward, you will learn to fit both the pieces together, that is, the frontend Angular application with the backend Java EE microservices. As each unit in a microservice promotes high cohesion, you will learn different ways in which independent units can be tested efficiently. Finishing off with concepts on securing your enterprise applications, this book is a handson guide for building modern web applications.What you will learn[•] Write CDI-based code in Java EE 8 applications[•] Build an understanding of microservices and what they mean in a Java EE context[•] Employ Docker to build and run microservice applications[•] Use configuration optionsto work effectively with JSON documents[•] Handle asynchronous task and write RESTAPI clients[•] Set the foundation for working on Angular projects with the fundamentals of TypeScript[•] Learn to use Angular CLI to add and manage new features[•] Secure Angular applicationsusing malicious attacks adopting JSON Web tokensWho this book is forThis book is for Java EE developers who would like to build modern enterprise web applications using Angular. No knowledge of Angular is required.

Magnetic resonance imaging (MRI) is a technique used in biomedical imaging and radiology to visualize internal structures of the body. Because MRI provides excellent contrast between different soft tissues, the technique is especially useful for diagnostic imaging of the brain, muscles, and heart.In the past 20 years, MRI technology has improved significantly with the introduction of systems up to 7 Tesla (7 T) and with the development of numerous post-processing algorithms such as diffusion tensor imaging (DTI), functional MRI (fMRI), and spectroscopic imaging. From these developments, the diagnostic potentialities of MRI have improved impressively with an exceptional spatial resolution and the possibility of analyzing the morphology and function of several kinds of pathology.Given these exciting developments, the Magnetic Resonance Imaging Handbook: Imaging of the Cardiovascular System, Thorax, and Abdomen is a timely addition to the growing body of literature in the field. Offering comprehensive coverage of cutting-edge imaging modalities, this book: Discusses MRI of the heart, blood vessels, lungs, breasts, diaphragm, liver, gallbladder, spleen, pancreas, adrenal glands, and gastrointestinal tract Explains how MRI can be used in vascular, posttraumatic, postsurgical, and computer-aided diagnostic (CAD) applications Highlights each organ's anatomy and pathological processes with high-quality images Examines the protocols and potentialities of advanced MRI scanners such as 7 T systems Includes extensive references at the end of each chapter to enhance further study Thus, the Magnetic Resonance Imaging Handbook: Imaging of the Cardiovascular System, Thorax, and Abdomen provides radiologists and imaging specialists with a valuable, state-of-the-art reference on MRI.

About This BookEfficiently use Data Structures, Language Constructs, & Handle AsynchronyMonitor the performance, Code Quality, & Resource OptimizationsBuild & Deploy Strategies for Large Scale TypeScript ProjectsWho This Book Is ForThis book is for people who have basic knowledge of TypeScript. Experience using JavaScript and familiarity with front end development are the prerequisites.What You Will LearnLearn about the critical rendering path, and the performance metrics involved along the sameExplore the detailed inner intricacies of a web browserBuild a large scale front end applications and learn the thought process behind architecting such an effortUnderstand the challenges of scalability and how TypeScript renders itself to the causeLearn efficient usage of TypeScript constructs to deliver high performance and avoid common mistakes and pitfalls that can hamper performanceMonitor performance, resolve and detect performance bottlenecks in production, and learn the tools involvedIn DetailIn a world where a tiny decrease in frames per second impacts customer engagement greatly, writing highly scalable code is more of a necessity than a luxury. Using TypeScript you get type checking during development. This gives you the power to write optimized code quickly. This book is also a solid tool to those who're curious to understand the impact of performance in production, and it is of the greatest aid to the proactive developers who like to be cognizant of and avoid the classic pitfalls while coding.The book will starts with explaining the efficient implementation of basic data Structures, data types, and flow control. You will then learn efficient use of advanced language constructs and asynchronous programming. Further, you'll learn different configurations available with TSLint to improve code quality and performance. Next, we'll introduce you to the concepts of profiling and then we deep dive into profiling JS with several tools such as firebug, chrome, fiddler. Finally, you'll learn techniques to build and deploy real world large scale TypeScript applications.

Leverage the cheapest and smallest computer to build exciting wearable-tech projects.Key Features[•] A practical and imaginative guide that exposes you to amazing wearable-tech projects[•] Create our own heart-rate monitor device and cool projects such as a Tweet-activated LED T-shirt[•] A practical guide packed with real-world, useful wearable-tech projectsBook DescriptionWith Wearable-Tech Projects with the Raspberry Pi Zero, you will begin with learning how to install the required software for your upcoming projects. You will also learn how to control electronic devices with the GPIOZero Python library. Next, you will be creating some stylish wearable-tech projects such as a motion-reactive LED cap and a Tweet-activated LED T-shirt. Toward the end of the book, you will be creating some useful health and fitness wearable-tech projects; these will help you monitor your heart rate, track your movements with GPS, and count your footsteps with your own pedometer. By the end of the book, you will have created a range of wearable-tech projects and learned enough about your Raspberry Pi Zero that you should be able to adapt these projects further or come up with your own creations!What you will learnMake use of your Raspberry Pi Zero to create wearable-tech projectsInterface with electronic devices and use Python to control them; incorporate these into real-world, practical, wearable-tech projectsAdd LED devices to clothing and connect them to your Pi ZeroChange how LEDs react based upon your movement or messages sent through TwitterCreate a pedometer and heart rate monitorCreate your own GPS trackerWho this book is forEveryone. While some prior knowledge of Python programming and use of the terminal on the Raspberry Pi would be advantageous, they are by no means necessary. Each chapter clearly sets the steps to be taken on your wearable-tech adventure. The first chapter assumes no prior knowledge to get your Pi Zero and you, up and running. The complexity of the electronic devices used, progress incrementally as you work through the chapters; there are clear steps to follow and pictures to help you at every turn along the way.

Publisher's Note: This edition from 2017 is outdated and not compatible with TensorFlow 2.x or any of the most recent updates to Python libraries. A new edition completely updated and revised for 2020 with seven additional chapters that cover RNNs, AI and big data, fundamental use cases, chatbots, and more, is now available. Build real-world Artificial Intelligence applications with Python to intelligently interact with the world around you. Key FeaturesStep into the amazing world of intelligent apps using this comprehensive guideEnter the world of Artificial Intelligence, explore it, and create your own applicationsWork through simple yet insightful examples that will get you up and running with Artificial Intelligence in no timeBook DescriptionArtificial Intelligence is becoming increasingly relevant in the modern world. By harnessing the power of algorithms, you can create apps which intelligently interact with the world around you, building intelligent recommender systems, automatic speech recognition systems and more. Starting with AI basics you'll move on to learn how to develop building blocks using data mining techniques. Discover how to make informed decisions about which algorithms to use, and how to apply them to real-world scenarios. This practical book covers a range of topics including predictive analytics and deep learning.What you will learnRealize different classification and regression techniquesUnderstand the concept of clustering and how to use it to automatically segment dataSee how to build an intelligent recommender systemUnderstand logic programming and how to use itBuild automatic speech recognition systemsUnderstand the basics of heuristic search and genetic programmingDevelop games using Artificial IntelligenceWho this book is forThis book is for Python developers who want to build real-world Artificial Intelligence applications. This book is friendly to Python beginners, but being familiar with Python would be useful to play around with the code. It will also be useful for experienced Python programmers who are looking to use Artificial Intelligence techniques in their existing technology stacks.

This book will teach you how to build robust asynchronous and event-driven applications with ease. About This Book Learn about Java 9's Flow API, Reactive programming along with Kafka and Mockito, and how these aspects are utilized by RxJava Build fast and concurrent applications with ease, without the complexity of Java's concurrent API and shared states, with the help of Spring Explore a wide variety of code examples to easily get used to all the features and tools provided by RxJava Who This Book Is For This book targets existing Java developers who want to understand Reactive programming and build responsive and resilient asynchronous applications using Reactive stream implementations. What You Will Learn Understand the Reactive Manifesto Grasp the Reactive Streams types introduced in Java 9 in the form of the Flow API Use RxJava, a Reactive Streams implementation, to build asynchronous applications Build responsiveness and resilience into applications using RxJava operators Demonstrate the usage of Hystrix, a latency and fault tolerance library from Netfl ix that uses RxJava Implement Reactive web applications using Spring Framework 5 and RxJava In Detail Reactive programming is an asynchronous programming model that helps you tackle the essential complexity that comes with writing such applications. Using Reactive programming to start building applications is not immediately intuitive to a developer who has been writing programs in the imperative paradigm. To tackle the essential complexity, Reactive programming uses declarative and functional paradigms to build programs. This book sets out to make the paradigm shift easy. This book begins by explaining what Reactive programming is, the Reactive manifesto, and the Reactive Streams specifi cation. It uses Java 9 to introduce the declarative and functional paradigm, which is necessary to write programs in the Reactive style. It explains Java 9's Flow API, an adoption of the Reactive Streams specifi cation. From this point on, it focuses on RxJava 2.0, covering topics such as creating, transforming,fi ltering, combining, and testing Observables. It discusses how to use Java's popular framework, Spring, to build event-driven, Reactive applications. You will also learn how to implement resiliency patterns using Hystrix. By the end, you will be fully equipped with the tools and techniques needed to implement robust, event-driven, Reactive applications. Style and approach This book is a tutorial about Reactive programming in Java using APIs as well as the RxJava library. Packed with a lot of well-described examples, it explains Reactive programming concepts in plain and readable language.

Over 50 practical and immediately applicable recipes to help you manage services in your enterprise environment efficientlyKey Features[•] Solve problems and challenges encountered while implementing or using ServiceNow in your organization[•] Helps you build core administration, management, and maintenance skills to automate and orchestrate your IT environment[•] Comes with recipes to improve the way you design and create automated workflowsBook DescriptionServiceNow is the ideal platform for you to create enterprise-level applications, giving borh requesters and fulfillers better visibility and access to a process. With this title we'll guide you through the world of ServiceNow, letting you take on the best the platform offers you with the least amount of hassle. Starting with the core configuration and management tasks, this book will help you build data-driven apps and it will also explore development best practices. You will learn to set up email notifications for users and work with the database view for reporting. Next, the book will guide you through creating various tasks from the workflow and show you how to make the most of the workflow utilities available in ServiceNow. Finally, the book will drive you through the auditing and diagnosing aspects of ServiceNow. By the end of this book, you will acquire immediately applicable skills to rectify everyday problems encountered on the ServiceNow platform. What you will learn[•] Grasp the basics, such as entering and navigation, required to implement ServiceNow[•] Perform core configuration and management tasks[•] Use the ServiceNow plugins to manage development[•] Build and publish custom applications for service management[•] Design data-driven apps to connect with outside worlds by getting into Client and server scripting[•] Configure alerts and notifications and understand e-mail troubleshooting and watermarking[•] Build and configure reports to set up your dashboard as per the requirement[•] Create and configure workflow activitiesWho this book is forThis book targets IT professionals and administrators who have some experience of working with ServiceNow already and are looking to solve regular or unique problems that surface when using ServiceNow. It's advisable to have a basic level of administration experience with ServiceNow. Familiarity with JavaScript is assumed.

Explore Implementation of core kernel subsystemsKey Features?Master the design, components, and structures of core kernel subsystems?Explore kernel programming interfaces and related algorithms under the hood?Completely updated material for the 4.12.10 kernelBook DescriptionMastering Linux Kernel Development looks at the Linux kernel, its internal arrangement and design, and various core subsystems, helping you to gain significant understanding of this open source marvel. You will look at how the Linux kernel, which possesses a kind of collective intelligence thanks to its scores of contributors, remains so elegant owing to its great design. This book also looks at all the key kernel code, core data structures, functions, and macros, giving you a comprehensive foundation of the implementation details of the kernel's core services and mechanisms. You will also look at the Linux kernel as well-designed software, which gives us insights into software design in general that are easily scalable yet fundamentally strong and safe. By the end of this book, you will have considerable understanding of and appreciation for the Linux kernel.What you will learnComprehend processes and files—the core abstraction mechanisms of the Linux kernel that promote effective simplification and dynamismDecipher process scheduling and understand effective capacity utilization under general and real-time dispositionsSimplify and learn more about process communication techniques through signals and IPC mechanismsCapture the rudiments of memory by grasping the key concepts and principles of physical and virtual memory managementTake a sharp and precise look at all the key aspects of interrupt management and the clock subsystemUnderstand concurrent execution on SMP platforms through kernel synchronization and locking techniquesWho this book is forIf you are a kernel programmer with a knowledge of kernel APIs and are looking to build a comprehensive understanding, and eager to explore the implementation, of kernel subsystems, this book is for you. It sets out to unravel the underlying details of kernel APIs and data structures, piercing through the complex kernel layers and gives you the edge you need to take your skills to the next level.

Containing papers carefully compiled for both their historical importance and contemporary relevance, Family Medicine: The Classic Papers brings together a team of experts, led by global family medicine leaders Michael Kidd, Iona Heath and Amanda Howe, who explain the importance of each selected paper and how it contributes to international health care, current practice and research. The papers demonstrate the broad scope of primary health care delivered by family doctors around the world, showcasing some of the most important research ever carried out in family medicine and primary care. This unique volume will serve as an inspiration to current family doctors and family medicine researchers and educators, as well as to doctors in training, medical students and emerging researchers in family medicine.

Advanced analytics on your Big Data with the latest Apache Spark 2.xKey Features[•]Master the art of real-time Big Data processing using Apache Spark 2.x[•]Perform machine learning, deep learning and streaming data analytics by extending the most up-to-date functionalities of Apache Spark[•]An advanced guide with a unique combination of tips, instructions and practical examples on using Apache Spark effectivelyBook DescriptionApache Spark is an in-memory, cluster-based Big Data processing system that provides a wide range of functionalities such as graph processing, machine learning, stream processing, and more. This book will take your knowledge of Apache Spark to the next level by teaching you how to expand Spark's functionality and build your data flows and machine/deep learning programs on top of the platform. The book starts with a quick overview of the Apache Spark ecosystem, and introduces you to the new features and capabilities in Apache Spark 2.x. You will then work with the different modules in Apache Spark such as interactive querying with Spark SQL, using DataFrames and DataSets effectively, streaming analytics with Spark Streaming, and performing machine learning and deep learning on Spark using MLlib and external tools such as H20 and Deeplearning4j. The book also contains chapters on efficient graph processing, memory management and using Apache Spark on the cloud. By the end of this book, you will have all the necessary information to master Apache Spark, and use it efficiently for Big Data processing and analytics. What you will learnGet to grips with the newly introduced features in Apache Spark 2.xPerform highly optimised unified batch and real-time data processing usingSparkSQL and Structured StreamingEvaluate large-scale Graph Processing and Analysis using GraphX and GraphFramesPerform advanced machine learning and deep learning with Spark MLlib, SparkML, SystemML, H2O and DeepLearning4JLearn how specific parameter settings affect overall performance of anApache Spark clusterApply Apache Spark in Elastic deployments using Jupyter and Zeppelin Notebooks, Docker, Kubernetes and the IBM CloudWho this book is forIf you are an intermediate-level Spark developer looking to master the advanced capabilities and use-cases of Apache Spark 2.x, this book is for you. Big Data professionals who wish to know how to integrate and use the features of Apache Spark to build a strong Big Data pipeline will also find this book to be a useful resource. A fundamental knowledge of Apache Spark and the Scala programming language is assumed.

A practical approach to conquering the complexities of Microservices using the Python tooling ecosystemKey FeaturesA very useful guide for Python developers who are shifting to the new microservices-based developmentA concise, up-to-date guide to building efficient and lightweight microservices in Python using Flask, Tox, and other toolsLearn to use Docker containers, CoreOS, and Amazon Web Services to deploy your servicesBook DescriptionWe often deploy our web applications into the cloud, and our code needs to interact with many third-party services. An efficient way to build applications to do this is through microservices architecture. But, in practice, it's hard to get this right due to the complexity of all the pieces interacting with each other. This book will teach you how to overcome these issues and craft applications that are built as small standard units, using all the proven best practices and avoiding the usual traps. It's a practical book: you'll build everything using Python 3 and its amazing tooling ecosystem. You will understand the principles of TDD and apply them. You will use Flask, Tox, and other tools to build your services using best practices. You will learn how to secure connections between services, and how to script Nginx using Lua to build web application firewall features such as rate limiting. You will also familiarize yourself with Docker's role in microservices, and use Docker containers, CoreOS, and Amazon Web Services to deploy your services. This book will take you on a journey, ending with the creation of a complete Python application based on microservices. By the end of the book, you will be well versed with the fundamentals of building, designing, testing, and deploying your Python microservices.What you will learnExplore what microservices are and how to design themUse Python 3, Flask, Tox, and other tools to build your services using best practicesLearn how to use a TDD approachDiscover how to document your microservicesConfigure and package your code in the best wayInteract with other servicesSecure, monitor, and scale your servicesDeploy your services in Docker containers, CoreOS, and Amazon Web ServicesWho this book is forThis book is for developers who have basic knowledge of Python, the command line, and HTTP-based application principles, and those who want to learn how to build, test, scale, and manage Python 3 microservices. No prior experience of writing microservices in Python is assumed.

Develop a simple, yet fully-functional modern web application using ASP.NET Core MVC, Entity Framework and Angular 5. Key Features[•] Based on the best-selling book ASP.NET Core and Angular 2[•] Easily build a complete single page application with two of the most impressive frameworks in modern development, ASP.NET Core and Angular[•] Bring together the capabilities and features of both Angular 5 and ASP.NET Core 2 for full stack development[•] Discover a comprehensive approach to building your next web project-From managing data, to application design, through to SEO optimization and securityBook DescriptionBecome fluent in both frontend and backend web development by combining the impressive capabilities of ASP.NET Core 2 and Angular 5 from project setup right through the deployment phase. Full-stack web development means being able to work on both the frontend and backend portions of an application. The frontend is the part that users will see or interact with, while the backend is the underlying engine, that handles the logical flow: server configuration, data storage and retrieval, database interactions, user authentication, and more. Use the ASP.NET Core MVC framework to implement the backend with API calls and server-side routing. Learn how to put the frontend together using top-notch Angular 5 features such as two-way binding, Observables, and Dependency Injection, build the Data Model with Entity Framework Core, style the frontend with CSS/LESS for a responsive and mobile-friendly UI, handle user input with Forms and Validators, explore different authentication techniques, including the support for third-party OAuth2 providers such as Facebook, and deploy the application using Windows Server, SQL Server, and the IIS/Kestrel reverse proxy.What you will learnUse ASP.NET Core to its full extent to create a versatile backend layer based on RESTful APIsConsume backend APIs with the brand new Angular 5 HttpClient and use RxJS Observers to feed the frontend UI asynchronouslyImplement an authentication and authorization layer using ASP.NET Identity to support user login with integrated and third-party OAuth 2 providersConfigure a web application in order to accept user-defined data and persist it into the database using server-side APIsSecure your application against threats and vulnerabilities in a time efficient wayConnect different aspects of the ASP. NET Core framework ecosystem and make them interact with each other for a Full-Stack web development experienceWho this book is forThis book is for seasoned ASP.NET developers who already know about ASP.NET Core and Angular in general, but want to know more about them and/or understand how to blend them together to craft a production-ready SPA.

Function literals, Monads, Lazy evaluation, Currying, and moreKey Features[•] Write concise and maintainable code with streams and high-order functions[•] Understand the benefits of currying your Golang functions[•] Learn the most effective design patterns for functional programming and learn when to apply each of them[•] Build distributed MapReduce solutions using GoBook DescriptionLex Sheehan begins slowly, using easy-to-understand illustrations and working Go code to teach core functional programming (FP) principles such as referential transparency, laziness, recursion, currying, and chaining continuations. This book is a tutorial for programmers looking to learn FP and apply it to write better code. Lex guides readers from basic techniques to advanced topics in a logical, concise, and clear progression. The book is divided into four modules. The first module explains the functional style of programming: pure functional programming, manipulating collections, and using higher-order functions. In the second module, you will learn design patterns that you can use to build FP-style applications. In the next module, you will learn FP techniques that you can use to improve your API signatures, increase performance, and build better cloud-native applications. The last module covers Category Theory, Functors, Monoids, Monads, Type classes and Generics. By the end of the book, you will be adept at building applications the FP way.What you will learn[•] Learn how to compose reliable applications using high-order functions[•] Explore techniques to eliminate side-effects using FP techniques such as currying[•] Use first-class functions to implement pure functions[•] Understand how to implement a lambda expression in Go[•] Compose a working application using the decorator pattern[•] Create faster programs using lazy evaluation[•] Use Go concurrency constructs to compose a functionality pipeline[•] Understand category theory and what it has to do with FPWho this book is forThis book is for Golang developers comfortable with OOP and interested in learning how to apply the functional paradigm to create robust and testable apps. Prior programming experience with Go would be helpful, but not mandatory.

Efficiently integrate OAuth 2.0 to protect your mobile, desktop, Cloud applications and APIs using Spring Security technologies.Key FeaturesInteract with public OAuth 2.0 protected APIs such as Facebook, LinkedIn and Google.Use Spring Security and Spring Security OAuth2 to implement your own OAuth 2.0 providerLearn how to implement OAuth 2.0 native mobile clients for Android applicationsBook DescriptionOAuth 2.0 is a standard protocol for authorization and focuses on client development simplicity while providing specific authorization flows for web applications, desktop applications, mobile phones, and so on. This book also provides useful recipes for solving real-life problems using Spring Security and creating Android applications. The book starts by presenting you how to interact with some public OAuth 2.0 protected APIs such as Facebook, LinkedIn and Google. You will also be able to implement your own OAuth 2.0 provider with Spring Security OAuth2. Next, the book will cover practical scenarios regarding some important OAuth 2.0 profiles such as Dynamic Client Registration, Token Introspection and how to revoke issued access tokens. You will then be introduced to the usage of JWT, OpenID Connect, and how to safely implement native mobile OAuth 2.0 Clients. By the end of this book, you will be able to ensure that both the server and client are protected against common vulnerabilities. What you will learnUse Redis and relational databases to store issued access tokens and refresh tokensAccess resources protected by the OAuth2 Provider using Spring SecurityImplement a web application that dynamically registers itself to the Authorization ServerImprove the safety of your mobile client using dynamic client registrationProtect your Android client with Proof Key for Code ExchangeProtect the Authorization Server from invalid redirectionWho this book is forThis book targets software engineers and security experts who are looking to develop their skills in API security and OAuth 2.0. Prior programming knowledge and a basic understanding of developing web applications are necessary. As this book's recipes mostly use Spring Security and Spring Security OAuth2, some prior experience with Spring Framework will be helpful.

This book provides detailed information on the nosology, pathology, pathogenesis, clinical presentation, diagnosis and treatment of fibro-inflammatory disorders, rare diseases that often display systemic organ involvement. Among the conditions considered are IgG4-related disease, sclerosing cholangitis, Hashimoto's and Riedel's thyroiditis, retroperitoneal fibrosis/chronic periaortitis, mediastinal fibrosis, Erdheim-Chester disease, gadolinium-induced fibrosis, and sclerosing mesenteritis. This group of entities is still poorly defined and is characterized by the common denominator of chronic inflammatory infiltrate admixed with abundant fibrosis. IgG4-related disease is the prototypical example. Systemic Fibroinflammatory Disorders is the first book to draw together information on these conditions. As these diseases often require an interdisciplinary approach, the book is addressed to specialists of different disciplines, especially internists, rheumatologists, nephrologists, clinical immunologists, and hematologists.

This fourth edition of the Oxford Textbook of Clinical Nephrology builds on the success and international reputation of the publication as an important resource for the practising clinician in the field. It provides practical, scholarly, and evidence-based coverage of the full spectrum of clinical nephrology, written by a global faculty of experts. The most relevant and important reference to clinical nephrology, this is an authoritative and comprehensive textbook combining the clinical aspects of renal disease essential to daily clinical practice with extensive information about the underlying basic science and current evidence available. Each section of the textbook has been critically and comprehensively edited under the auspices of a leading expert in the field. This new edition has been significantly expanded and reapportioned to reflect developments and new approaches to topics, and includes treatment algorithms to aid and enhance patient care where possible. The fourth edition offers increased focus on the medical aspects of transplantation, HIV-associated renal disease, and infection and renal disease, alongside entirely new sections on genetic topics and clinical and physiological aspects of fluid/electrolyte and tubular disorders. The emphasis throughout is on marrying advances in scientific research with clinical management. Richly illustrated throughout in full colour, this is a truly modern and attractive edition which reinforces the Oxford Textbook of Clinical Nephrology's position as an indispensable reference work of consistent quality and reliability. Enriched and refined by careful revision, this new edition continues the tradition of excellence. This print edition of The Oxford Textbook of Clinical Nephrology comes with a year's access to the online version on Oxford Medicine Online. By activating your unique access code, you can read and annotate the full text online, follow links from the references to primary research materials, and view, enlarge and download all the figures and tables. Oxford Medicine Online is mobile optimized for access when and where you need it.

This title takes a comprehensive approach, exploring the physical, social, psychological, and spiritual dimensions of death, dying, and bereavement.Through personal stories from real people, Death, Dying, and Bereavement provides readers with a context for understanding their changing encounters with such difficult concepts.

This is the eBook of the printed book and may not include any media, website access codes, or print supplements that may come packaged with the bound book. For courses in experimental foods, food science, and related topics Preparing aspiring professionals with clearly written, in-depth scientific coverage of food and its safe preparation. Never before has food received so much attention. Today's news shines a spotlight on food, food science, and nutrition — beckoning today's readers to an exciting career in this essential industry. Foods: Experimental Perspectives, Eighth Edition blends the underlying science with discussion of GMOs, sustainability, healthy and trendy food choices, and other current consumer issues. Its clear presentation of the science guides readers through complex concepts that influence practices in food preparation and product development. The study of foods begins with an in-depth presentation of carbohydrates and food sources, followed by a careful look at lipids, and ultimately proteins and their principal sources. Aspects of the food supply, including safety, preservation, and additives are then examined. Discussion of the research process and evaluation techniques used in food research and product development close the text. Professional vocabulary is developed through margin definitions and a substantial glossary, while other learning aids — chapter objectives, summaries, study questions,'Food for Thought'boxes, and photos — support the reader's journey through the exciting look at food, food science, and food safety.

Since the first edition of Principles of Behavior, the authors have sought to address the unique needs of students. This title has been written so that students of all levels will benefit from a solid introduction to the principles of behavior. The authors have laid the groundwork for behavior analysis through an exploration of experimental, applied, and theoretical concepts. Case studies and everyday examples help readers apply principles of behavior to real life.About the Book:This book also is integrated with the Behavior Analyst Certification Board task list and serves as an excellent introduction to many of the BACB tasks.

The health-related effects of asbestos have long been mired in controversy, with industry and plaintiff attorneys playing a significant role. This comprehensive book provides a balanced and extensive evidence-based critical analysis of the literature concerning asbestos-related diseases, from a scientific and historical perspective. The book presen

By using the example of Germany and Poland this multi-level policy dependency analysis by Marco Wedel researches constraints and dependencies of the European Integration of the promotion of renewable energy source electricity (RES-E). To gain insightful results, the author does not only take a look at the implementation effectiveness of the relevant Directive 2009/28/EC, but much more generally analyses the potentially conflicting polity implications of the entities involved, as well as their respective policy preferences and processes in light of RES-(E). Combined, these give rise to multi-level constraints and dependencies for the European Integration of RES-(E) promotion.

Urologie für Klinik und Praxis zum Nachschlagen und Lernen!Das in 2 Bände gegliederte Standardwerk füllt eine lange unbesetzte Lücke in der Urologie. In Zusammenarbeit mit der Deutschen Gesellschaft für Urologie und der Akademie der Deutschen Urologen haben die Experten aus Deutschland, Österreich und der Schweiz ein einzigartiges Buch für alle Urologen geschaffen.· Die ganze Urologie in 2 Bänden: von der bildgebenden Diagnostik bis zur medikamentösen und operativen Therapie· Umfangreiche Ausstattung mit hunderten hervorragenden Zeichnungen, Fotografien, Grafiken und Tabellen · An den neuesten Leitlinien orientiert· Spezielle Tipps für Praxis und Klinik· Hervorragend didaktisch strukturiert: ideal zum detaillierten Lernen für die Facharztprüfung·Zusammenfassung der wichtigsten Fakten eines Kapitels erleichtert die schnelle Informationsaufnahme, wenn die Zeit knapp ist'Die Urologie': Ein Buch, an dem man als Urologe nicht vorbeikommt!

Sixième édition, entièrement réécrite et augmentée de l'ouvrage de référence en Médecine interne depuis plus de trente ans.Ce traité est aujourd'hui édité pour la première fois intégralement en couleur.L'équipe d'une centaine d'auteurs, tous référents dans leur spécialité, a révisé et actualisé l'ensemble des chapitres.Sont développées de façon complète et précise : l'inflammation, l'immunité, la génétique et l'anatomopathologie ; les maladies auto-immunes ; les vascularites ; les manifestations et affections systémiques ; les maladies systémiques en pédiatrie ; les autres affections systémiques (GVH, DIP, etc.) ; les thérapeutiques (depuis les immunosuppresseurs jusqu'aux biothérapies).La richesse de l'iconographie en couleur, les tableaux, les bibliographies et l'index détaillé ajoutent à la qualité et à l'exhaustivité de ce traité, devenu un classique.

The book “Textbook of Advanced Nursing Practice” covers almost all the aspects of advanced nursing practice. As per the syllabi, the book is divided into 10 units; Unit I deals with nursing history, profession, role of regulatory bodies, legal and ethical issues in nursing, role of research, education and management in nursing. Unit II describes in detail all the methods of healthcare delivery system in India followed by Unit III that covers all matters related to genetics including genetic testing, counseling and its practical applications in nursing. Unit IV explains all aspects of Epidemiology while Unit V covers the topics biopsychosocial pathology that includes common homeostatic problems, infection prevention and innovations in nursing. Philosophies and theories of nursing are discussed in detail in Unit VI. The entire nursing process is discussed in Unit VII. Unit VIII includes topics such as life processes, personality development and disorders, stress and management, principles and techniques of counseling. Unit IX covers various nursing practices and the final unit (Unit X) includes the basics to computers, importance of computers in nursing education and hospital management information system.