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Functional Foods and Chronic Disease: Role of Sensory, Chemistry and Nutrition explores the range of functional foods that are effective against a wide range of chronic diseases and addresses the impact of functional food bioactive compounds on organoleptic properties. Beginning with an introduction that details the key sensory and advanced instrumental methods essential for addressing the common problems associated with designing functional foods, the book also addresses the impact of aging and chronic diseases on sensory acuity as well as the effectiveness of functional foods in treating a wide range of chronic diseases. Sections highlight the need for acceptable functional foods for individuals suffering from a wide range of chronic diseases and contain practical recommendations for their development. Food scientists, nutritionists, dietitians, food product developers, food supplement producers, food ingredient developers, natural product scientists, herbalists, and pharmacists, as well as students studying related areas, will benefit from this important resource. - Highlights the need for acceptable functional foods for individuals suffering from a wide range of chronic diseases - Includes case studies, applications, literature reviews, and a summary of recent developments in the field - Provides suggestions for improving the organoleptic properties of functional foods

Development of Gluten-Free Pasta summarizes current progress in the development of gluten-free (GF) products, focusing particularly on pasta products. Presented in 11 chapters, the book focuses on the role of prebiotic fiber, hydrocolloids, fruit and vegetable by-product pomace and the physical, microstructural, sensory, and nutritional properties of the gluten-free pasta. The science of gluten intolerance is explained as well, with all relevant literature gathered and summarized in one place. Hence, this book lays a very solid foundation for the development of GF pasta which can be exploited as an essential therapeutic tool in the prevention of celiac disease. This comprehensive reference, written by world renowned scientists who elaborate on the study of different selected additives of plant origin, provides immense assistance in the field of research as many areas are still unexplored in the field of cereal science & technology. - Provides a comprehensive application of pseudocereals, hydrocolloids, and prebiotic dietary fiber in the development of gluten-free pasta - Brings holistic and integrated coverage of the role of plant derived ingredients in the development of gluten-free pasta - Covers the utilization of pseudo cereals for food, nutritional, and economical security

Encyclopedia of Food Allergy, organized in 10 sections, with ~200 chapters, and written by world-renowned clinician-scientist authors, is the most comprehensive resource for food allergy ever compiled. With online and physical presence, intuitive and easily accessible organization of information, the reader can quickly access overview and general topics as well as detailed information to inform solutions to clinical or research questions. Research topics provide the necessary background for the novice as well as the details required for those in the field. Clinical topics provide comprehensive and practical information, with generous use of tables, figures, and key points/clinical pearls, to inform clinical decision-making, and promote evidence-based management decisions. Food allergy may affect up to 10% of the population in developed countries and appears to be increasing in prevalence worldwide, with many food allergies proving life-long, severe and potentially fatal. The last decade has witnessed a sea change response to the impact of food allergy through basic science research on the immunology, food science research on the triggers, clinical approaches to daily management, treatment and prevention, and an increasing understanding of the psychosocial and societal implications and how to address them. With the expanding breadth and depth of the field, there is no existing comprehensive resource available for those professionals interested in learning about or contributing to food allergy research and clinical care. This is a complete resource covering broad and detailed aspects of food allergy and adverse food reactions for clinicians, researchers, regulators, food industry, students and other stakeholders who need and will benefit from a rich resource with in-depth and practical information. - Presents in-depth, comprehensive coverage from an outstanding international author base of domain experts - Ideal for new researchers and clinicians who will have a single resource that includes general topics to get them started - Includes access to detailed information in their areas of work AND for many related topics that will help improve their research or clinical care

The term nutraceuticals is applied to the products isolated from the herbal sources, nutrients or dietary supplements, processed foods, (cereals, soup and beverages) and specific diets, that may also used as medicine other than nutrition. It usually refers to the foods derived products which may sell in medicinal form, possessing physiological benefits to the host while promoting health and wellness and provide protection against chronic disorders. They may also increase the life expectancy, delay the aging and/or support the structure and function of the body organs. Demand for nutraceuticals with potential to prevent and treat chronic disorders has been interestingly increasing over the past few years. Based on food sources, nutraceuticals are classified into dietary fibers, probiotics, prebiotics, polyunsaturated fatty acids (PUFAs), vitamins, polyphenols and spices. A dietary supplement is generally considered as product containing vitamins, minerals, amino acids, and medicinal plants that are indented to be used to supplement the diet or a concentrate, metabolite, constituent, extract, or combinations of these ingredients. Broadly, nutraceuticals are any of these ingredients or supplements using for health purposes other than nutrition. This book on the fundamentals of Nutraceuticals is organized in two parts i.e., the introductory aspects of macro- and micro-nutrients, gut microbiota regulation, nutraceuticals and drug interactions, while the second part is focusing on the biological benefits of nutraceuticals in different disease states. Besides, this book is also addressing the safety aspects of nutraceuticals and phytotherapeutic support in pregnancy. Including contributions from the experts in the field, target audience (pharmacists, nutritionists, other healthcare providers, and researchers in food and nutrition sector) will be benefited with the updated literature on nutraceuticals and dietary supplements.

Core Topics in General & Emergency Surgery provides a short, up-to-date and practical reference guide for surgical trainees and established consultants needing a refresher. The seventh edition has been edited and fully revised by respected experts in their fields, and provides a full list of current references and relevant resources. It covers a range of topics relevant to all areas of surgical practice – beyond surgical knowledge – that are essential for enhanced patient outcomes. These include quality improvement in emergency surgery, evaluation of new technology, evaluation of surgical literature, and human factors. This volume is part of the Companion to Specialist Surgical Practice series, the pre-eminent reference for trainees in general surgery and those preparing for the FRCS examinations. Each volume summarises key issues within each surgical sub-specialty and provides evidence-based recommendations to support practice. - Covers relevant topics not found in other surgical textbooks – essential to improve surgical outcomes - Concise and easy to follow – ideal for exam revision or as a refresher aid - Fully updated with latest evidence on recent developments, management issues and operative procedures - International authorship offers a world view - Evidence-based recommendations to support practice - Key references to support content, plus a comprehensive list of references in the accompanying eBook - Links to recommended online videos for further learning - New chapters on surgical technology, quality improvement in emergency surgery - All chapters revised and updated

Colorectal Surgery provides a short, up-to-date and practical reference guide for surgical trainees and established consultants needing a refresher. The seventh edition has been edited and fully revised by respected experts in their fields, and provides a full list of current references and relevant resources. It includes recent developments in colorectal surgery, including changes to colorectal cancer screening, multimodal therapy for rectal cancer and changes to the terminology and management of anal neoplasia. Several new authors and co-authors have joined the expert team. This volume is part of the Companion to Specialist Surgical Practice series, the pre-eminent reference for trainees in general surgery and those preparing for the FRCS examinations. Each volume summarises key issues within each surgical sub-specialty and provides evidence-based recommendations to support practice. - Concise and easy to follow – ideal for exam revision or as a refresher aid - Fully updated with latest evidence on recent developments, management issues and operative procedures - Details of relevant investigations and evidence-based recommendations to support practice - Key references to support content, plus a comprehensive list of references in the accompanying eBook - Links to recommended online videos for further learning - Several new expert authors - New chapters on colon cancer, rectal cancer, anal neoplasia, Crohn's disease and anal fistula, - Changes in colorectal cancer screening and the use of faecal immunohistochemical testing - Changes and terminology and management of anal neoplasia

Sustainable Food Science: A Comprehensive Approach provides a timely resource on new materials and ingredients currently available in the food industry, along with cutting-edge research on how to develop and secure sustainable food for a growing world population. With contributions from international experts and an outstanding editing team, the book covers sustainable sources of ingredients for the food industry, i.e., pulses, soybeans, peanuts, along with prospective and emerging sources such as industrial hemp, insects, algae, etc. In addition, other sections cover sustainable processes for new food sources and new food design, such as microbiological and biotechnological processes and dairy and meat substitutes. Users will value the clear-cut, in-depth and expert assessment of each topic and appreciate its sensible and logical hierarchical structure. This reference work will provide expert guidance for food scientists of all levels – both in academia or industry. - Updates on the latest sustainable sources of ingredients for the food industry, i.e., pulses, soybeans, peanuts, and more - Covers prospective and emerging sources such as industrial hemp, insects, algae, etc. - Provides content on sustainable processes for new food sources and new food design, such as microbiological and biotechnological processes alongside processes for obtaining dairy and meat substitutes

Encyclopedia of Food Safety, Second Edition, Four Volume Set provides an authoritative one-stop reference work covering all aspects of the field. Specific focus lies in the book's coverage of key industry developments over the last ten years, including: (i) detailed understanding of infectious agents and toxins and their route into the food chain; (ii) sophisticated detection and identification methods; (iii) effective control mechanisms, like heat treatment, refrigeration and sanitizers; (iv) education of food processors, handlers and consumers about safe food handling practices; (v) sanctioned food production, processing, storage and transport control protocols, like HACCP; and (vi) a strong policy and regulatory environment. With approximately 270 outstandingly written chapters from the world's leading experts in food science, the book covers all aspects of food safety along the entire food chain and in one complete work, thus providing the ideal reference tool for professionals working across the multiple scientific disciplines and technologies that constitute modern food safety. - Provides an up-to-date,'one-stop'resource that will bridge the gap in current knowledge - Intuitively organized into 9 sections over 4 volumes – providing an excellent overview of the field - Contains approximately 270 chapters written by a global team of experts in food science and safety - Ensures relevance to scientists across a variety of fields, such as food science, agriculture, health and climate change

The Gut-Brain Axis: Dietary, Probiotic, and Prebiotic Interventions on the Microbiota, Second Edition presents the most advances on how the gut microbiome influences central nervous system and brain function introduced in the first edition. The book also describes how environmental influences which affect the microbiota, including, diet, exercise, and early-life, impact on the gut-brain axis. The second edition contains new chapters on metabolomics and the gut-brain-axis; dietary factors in the maintenance of a healthy brain ; the role of gut microbes in neurodegenerative disorders; the link between exercise and the gut-brain-axis; and infant Nutrition, the microbiome and neurodevelopment. In addition, the second edition presents coverage of mechanisms underlying neurological disease; approaches to investigate the role of the microbiome in brain and behavior, and'next generation'probiotics and prebiotics. The Gut-Brain Axis: Dietary, Probiotic, and Prebiotic Interventions on the Microbiota, Second Edition continues to be the'go-to resource for further exploration of the microbiota. - Includes five new chapters focused on metabolomics and the gut-brain axis; dietary polyphenols to maintain healthier brain measures and cognitive function; the role of gut microbes in neurodegenerative disorders, exploration of exercise and the gut-brain axis, and coverage of infant nutrition, the microbiome, and neurodevelopment - Addresses the role of the microbiota in several significant disorders characterized by disruption of the gut-brain axis - Focuses on specific ways by which the microbiota can be manipulated to influence gut-brain communication - Examines common mechanisms and pathways by which the microbiota may influence brain and behavior and how environmental factors influence the microbiome - Discusses strategies to explore the contribution of the microbiome to the gut-brain axis; methods to enhance therapeutic strategies targeted toward the microbiota; and regulatory consideration

Ever since the beginnings of agriculture, cereals have provided unlimited health benefits to mankind as a staple food in our diet. Cereals are rich in complex carbohydrates that provide us ample energy, and help to prevent many diseases such as constipation, colon disorders, and high blood sugar levels. They enrich our overall health with abundant proteins, fats, lipids, minerals, vitamins, and enzymes. In every part of the world cereals are consumed for breakfast, lunch or dinner. Cereal Grains: Composition, Nutritional Attributes, and Potential Applications provides an overview of cereals including their properties, chemical composition, applications, postharvest losses, storage, and quality.Various well-versed researchers across the globe share their knowledge and experience covering cereal's role in food security, allergens in grains, phytochemical profile, industrial applications, health benefits, global standard of cereals, and recent advances in cereal processing.Key Features: Contains comprehensive information on general composition and properties of cereals. Discusses the recent advances in cereal technology Provides knowledge on bioactive characterization of cereal grains Contain information on future aspect of grain quality and allergens in cereal grains This handbook is a valuable resource for students, researchers, and industrial practitioners who wish to enhance their knowledge and insights on cereal science. Researchers, scientists, and other professionals working in various cereal processing industries and other horticultural departments will also find the comprehensive information relevant to their work.

••Selected for Doody's Core Titles® 2024 in Nutrition•• Encyclopedia of Human Nutrition, Fourth Edition, a Four Volume Set, provides updated information on the foundations of nutrition science, along with the biology and functions of vitamins and other essential nutrients present in the human diet. The book's content offers a modern understanding of the links between diet and health effects, including diseases of recognized nutritional etiology. This overview of the genetic and molecular aspects of nutrient-health interrelationships includes important content on topics like nutrigenomics, metabolomics and the microbiome. In addition, the book provides global context, particularly on the issue of food production, sustainability and climate change. The new edition carries on the legacy of a reference work that comprehensively offers a one-source, integrated bank of information on all three areas – food, nutrition science and clinical nutrition. - Provides an excellent overview of the field of human nutrition - Includes interdisciplinary chapters written by experts from around the world – chapters written by academics and practitioners from various fields and regions ensure the knowledge within is easily understood by, and applicable to, a large audience - Ideal for scientists in the fields of food science, biology, physiology, agriculture and climate change

Comprehensive Pharmacology, Seven Volume Set is organized into twelve sections that explore therapeutic areas, with a total of 320 comprehensive articles and 6,800 pages of important findings. Sections contain highly detailed coverage of information that has been overseen by an editorial board made up of well-respected, field leading experts. The content in this book offers readers an in-depth and easily accessible reference work on every aspect of pharmacological research surrounding the pharmacology of all therapeutic applications of drugs, their mechanism of action and their therapeutic values. These elements are essential as drugs are almost never tested and developed in the actual therapeutic system, but rather in test systems from which parameters must be determined to predict activity in systems of varying ambient physiology. As different technologies rapidly evolve, there is an ever-increasing level of knowledge about the pharmacology of known drugs, along with increasing capability to utilize pharmacological systems to predict new drug activity, all of which must be communicated to professionals in varying fields. - Contains chapters that follow a consistent and templated approach, resulting in well-structured content that enhances user experience and appeal - Offers a comprehensive review on a wealth of information on pharmacology and how it utilizes concepts and techniques from a broad array of sciences, ranging from chemistry to physiology to medicine - Includes a wider use of color and multimedia content, with interactive features, links, computational modeling and animations to illustrate the effects of toxic substances in various contexts

Comprehensive Gut Microbiota, Three Volume Set provides new insights into gut microbiota as a critical mediator of human health and well-being. Comprehensive chapters, split across three volumes, present trusted and authoritative sources of information for novel human gut microbiome and health research. The book focuses on the fascinating intestinal microbiome and its interaction with food, food bioactive components, nutrition and human health. Chapters address the core science in the microbiota field and draw links between the microbiome, food, nutrition and health interaction. The text reflects the current state of evidence available in the field of microbiota, its regulation at the individual and population level, and the importance of the microbiome to human health. Each section includes introductory chapters that present key concepts about the section objective. Later sections focus on the novel findings of the gut microbiome, food and nutrition science. Human studies and systematic literature reviews are also discussed throughout the work. - Provides a comprehensive introduction to gut microbiota research and its role and relation to human health - Consolidates new research on how gut microbiota affects nutrition and vice versa, offering increased understanding of methodologies and the complexity of microbiome-health science - Written by leading experts from various fields and regions, ensuring that the knowledge within is easily understood by, and applicable to, a large audience

Value Addition in Food Products and Processing using Enzyme Technology offers an updated review regarding the potential impact of new enzymes and enzyme technology on the food sector. The book brings together novel sources and technologies regarding enzymes in value added food development, food production, food processing, food preservation, food engineering and food biotechnology. It will be extremely useful for different types of readers, including food scientists, academic and food biotechnologists, but will also be ideal for students studying food-related courses. This book includes concise and up-to-date research information from multiple independent scientific papers from around the world. This is a essential, multidisciplinary text for research and development professionals, research scientists, and academics in food, biotechnology, and agriculture industries. It addresses safety issues and includes the sources, screening, immobilization and application of food-grade enzymes in food. - Presents research data from experts - Includes emerging industry topics such as baby food and food safety - Offers methodologies of enzymes in diagnostics for food testing and analysis - Emphasizes enzyme technology through a microbial biotechnological lens - Includes bakery and confectionery products, meat and poultry products, vegetables, food ingredients, functional foods, flavors and food additives and seafood

This 5th edition of this essential textbook continues to meet the growing demand of practitioners, researchers, educators, and students for a comprehensive introduction to key topics in biomedical informatics and the underlying scientific issues that sit at the intersection of biomedical science, patient care, public health and information technology (IT). Emphasizing the conceptual basis of the field rather than technical details, it provides the tools for study required for readers to comprehend, assess, and utilize biomedical informatics and health IT. It focuses on practical examples, a guide to additional literature, chapter summaries and a comprehensive glossary with concise definitions of recurring terms for self-study or classroom use.Biomedical Informatics: Computer Applications in Health Care and Biomedicine reflects the remarkable changes in both computing and health care that continue to occur and the exploding interest in the role that IT must play in carecoordination and the melding of genomics with innovations in clinical practice and treatment. New and heavily revised chapters have been introduced on human-computer interaction, mHealth, personal health informatics and precision medicine, while the structure of the other chapters has undergone extensive revisions to reflect the developments in the area. The organization and philosophy remain unchanged, focusing on the science of information and knowledge management, and the role of computers and communications in modern biomedical research, health and health care.

This new edition of the popular Pharmacology case studies for nurse prescribers has been thoroughly revised in the light of the latest research and guidance from NICE, the British National Formulary (BNF), the Royal Pharmaceutical Society, the Nursing and Midwifery Council and the Royal College of Nursing. While the first edition was aimed at students undertaking the non-medical prescribing modules, this updated text has broadened its scope and is relevant to all trainee and qualified nurse prescribers. There are new and additional chapters on pregnancy and breastfeeding, sexual health and contraception, and prescribing for frailty syndrome in the elderly. The latest developments in pharmacology (such as the emergence of biosimilar drugs) are included in the text; and all the chapters from the first edition have been revised and updated by expert healthcare practitioners. Meanwhile, the practical approach and helpful features that made the first edition so popular remain unchanged. The authors offer a basic introduction to pharmacological concepts, embedded in specific conditions, through case studies and self-assessment questions. By utilising a case study approach, they enable the reader to link pharmacological concepts with clinical practice. Reading this book, and carrying out the numerous self-assessment activities, will give the reader an appreciation of the value of having a sound pharmacological knowledge base in order to deliver safe practice, effective prescribing and improved patient care.

These volumes make new contributions to the history of psychiatry and society in three ways: First, they propose a theory of values and ideology influencing the evolution of psychiatry and society in recurring cycles, and survey the history of psychiatry in recent centuries in light of this theory. Second, they review the waxing, prominence, and waning of Community Mental Health as an example of a segment of this cyclical history of psychiatry. Third, they provide the first biography of Erich Lindemann, one of the founders of social and community psychiatry, and explore the interaction of the prominent contributor with the historical environment and the influence this has on both. We return to the issue of values and ideologies as influences on psychiatry, whether or not it is accepted as professionally proper. This is intended to stimulate self-reflection and the acceptance of the values sources of ideology, their effect on professional practice, and the effect of values-based ideology on the community in which psychiatry practices. The books will be of interest to psychiatric teachers and practitioners, health planners, and socially responsible citizens.

Explore the latest research in biopharmaceutics from leading contributors in the field In Biopharmaceutics - From Fundamentals to Industrial Practice, distinguished Scientists from the UK's Academy of Pharmaceutical Sciences Biopharmaceutica Focus Group deliver a comprehensive examination of the tools used within the field of biopharmaceutics and their applications to drug development. This edited volume is an indispensable tool for anyone seeking to better understand the field of biopharmaceutics as it rapidly develops and evolves. Beginning with an expansive introduction to the basics of biopharmaceutics and the context that underpins the field, the included resources go on to discuss how biopharmaceutics are integrated into product development within the pharmaceutical industry. Explorations of how the regulatory aspects of biopharmaceutics function, as well as the impact of physiology and anatomy on the rate and extent of drug absorption, follow. Readers will find insightful discussions of physiologically based modeling as a valuable asset in the biopharmaceutics toolkit and how to apply the principles of the field to special populations. The book goes on to discuss: Thorough introductions to biopharmaceutics, basic pharmacokinetics, and biopharmaceutics measures Comprehensive explorations of solubility, permeability, and dissolution Practical discussions of the use of biopharmaceutics to inform candidate drug selection and optimization, as well as biopharmaceutics tools for rational formulation design In-depth examinations of biopharmaceutics classification systems and regulatory biopharmaceutics, as well as regulatory biopharmaceutics and the impact of anatomy and physiology Perfect for professionals working in the pharmaceutical and biopharmaceutical industries, Biopharmaceutics - From Fundamentals to Industrial Practice is an incisive and up-to-date resource on the practical, pharmaceutical applications of the field.

This book is concerned with people who are approaching the end of their lives, as well as with the personal and professional caregivers who accompany them during this last stage. It describes attitudes and coping techniques among seriously or terminally ill people, as well as the care, support and environmental conditions that can help them shape the end of life in the best way possible in accordance with their own ideas. The author=s aim in the book is to provide support for people in developing an accepting attitude towards the finiteness of life and in clearly articulating to their caregivers what their ideas of a good life are.?This is a major work that places all end-of-life issues in a kinder, more serious, and more confident light. Well worth reading for everyone in relation to their own life, and for doctors, nurses, pastoral caregivers, counselors and all those voluntarily involved in providing humane care for seriously ill, very elderly and dying people. A book that is a wonderful read.= Dr. Matthias Mettner, Director of Studies for?Palliative Care and Organizational Ethics & Interdisciplinary Continuing Education Switzerland=, and Program Director of the Health and Medicine Forum, Zurich.

Rapid advances along all the frontiers of biological sciences necessitate frequent review of the state of our knowledge not only to keep our self up to date but also to ponder over the various strategies ought to be adopted for further resolution of the science in all its aspects. Advances in biological sciences go beyond molecular base science therefore interest continues to grow still higher and more. The combination of multidisciplinary research in plants, animals, microorganisms and their interaction has taken the life to the greatest extent for the wide horizons of life. This book “Emerging Trends and Challenges in Biosciences” provides an excellent, up-to-date discussion of the state of knowledge and fills an important information gap. This book emphasized the significance of modern biological tools and innovations for the development of eco-friendly and sustainable bioprocesses and products. This book will be useful to a wide array of scientists including biologists, academicians and other industrialists to encourage integration of life sciences for better understanding of the complexity and diversity of life processes.

Offering a state-of-the-art, authoritative summary of the most relevant scientific and clinical advances in the field, Principles and Practice of Movement Disorders provides the expert guidance you need to diagnose and manage the full range of these challenging conditions. Superb summary tables, a large video library, and a new, easy-to-navigate format help you find information quickly and apply it in your practice. Based on the authors'popular Aspen Course of Movement Disorders in conjunction with the International Parkinson and Movement Disorder Society, this 3rd Edition is an indispensable resource for movement disorder specialists, general neurologists, and neurology residents. - Explores all facets of movement disorders, including the latest rating scales for clinical research, neurochemistry, clinical pharmacology, genetics, clinical trials, and experimental therapeutics. - Provides the essential information you need for a clinical approach to diagnosis and management, with minimal emphasis on basic science. - Reflects recent advances in areas such as the genetics of Parkinsonian and other movement disorders, diagnostic brain imaging, new surgical approaches to patients with movement disorders, and new treatment guidelines for conditions such as restless legs syndrome. - Features a reader-friendly, full-color format, with plentiful diagrams, photographs, and tables. - Includes access to several hundred updated, professional-quality video clips that illustrate the manifestations of all the movement disorders in the book along with their differential diagnoses.

Immunopathology of Celiac Disease, Volume 359 presents the latest release in this ongoing series on novel and widely studied aspects of celiac disease pathogenesis. Topics covered in this new volume include Omics of Celiac Disease, Implication of HLA genes in Celiac Disease, Macrophages & Dendritic Cells in Celiac Disease, Tight junction disruption in the development of celiac disease, Implication of epithelial cell dysfunction in CeD, Involvement of p31-p43 gluten peptide in the celiac disease related immune/inflammatory response, The biology of refractory celiac disease, Involvement of lncRNAs in Celiac disease pathogenesis, and more. - Provides up-to-date and extensive reviews of different aspects of celiac disease pathogenesis - Includes original figures that help readers understand the complex pathways involved in the disease - Covers research on different aspects of the disease which involves the introduction of a wide range of technologies

Multidisciplinary Interventions for People with Diverse Needs is a book written from an interdisciplinary perspective with the objective of helping readers to understand the problems faced by people with special needs. Key Features: - provides an updated theoretical and contextual foundation of medical issues - provides information about the meaning, evaluation and intervention of the problems related to a variety of debilitating diseases and disability conditions (dementia, language disorders, diabetes, alterations of consciousness, celiac disease and disability in general) - contains an accessible, well written, didactic text which is useful to both students and working professionals The book equips the reader with information about different approaches to medical and social issues that arise when dealing with persons who are experiencing some degree of disability. For teachers and working professionals, the handbook serves as a guide for teaching, for the development of the structure of training courses, for the design of evaluation models and intervention of the topics addressed in the book. The combination of information about the professional and human aspects of special needs education makes this book a useful reference for pedagogues, psychologists, students, teachers and professionals involved in social science, healthcare, and sports medicine, among other fields.

The immunologist and bestselling author Attilio Speciani dispels the clichés about so-called ‘food intolerances'and guides the reader to a healthy and better relationship with food. Colitis, migraines, hormonal changes, arthritis, autoimmune diseases, imbalances of metabolism and many other disorders, from the most common to the most severe, are often related to diet. There is a close relationship between food and health, and when the natural and physiological relationship with food changes, due to food excesses or the repeated introduction of food, the organism generates measurable inflammatory signals that induce and maintain many conditions or diseases.

This edited research monograph brings together contributions from computer scientists, biologists, and engineers who are engaged with the study of evolution and how it may be applied to solve real-world problems. It also serves as a Festschrift dedicated to Erik D. Goodman, the founding director of the BEACON Center for the Study of Evolution in Action, a pioneering NSF Science and Technology Center headquartered at Michigan State University. The contributing authors are leading experts associated with the center, and they serve in top research and industrial establishments across the US and worldwide. Part I summarizes the history of the BEACON Center, with refreshingly personal chapters that describe Erik's working and leadership style, and others that discuss the development and successes of the center in the context of research funding, projects, and careers. The chapters in Part II deal with the evolution of genomes and evolvability. The contributionsin Part III discuss the evolution of behavior and intelligence. Those in Part IV concentrate on the evolution of communities and collective dynamics. The chapters in Part V discuss selected evolutionary computing applications in domains such as arts and science, automated program repair, cybersecurity, mechatronics, and genomic prediction. Part VI deals with evolution in the classroom, using creativity in research, and responsible conduct in research training. The book concludes with a special chapter from Erik Goodman, a short biography that concentrates on his personal positive influences and experiences throughout his long career in academia and industry.

The Autoimmune Diseases, Sixth Edition, emphasizes the'3 P's'of 21st Century medicine: precision, prediction and prevention. Topics cover the modern systems approach to biology that involves large amounts of personalized, ongoing physiologic data ('omics') coupled with advanced methods of analysis, new tests of genetic engineering, such as CRISPR, auto inflammatory diseases, autoimmune responses to tumor immunotherapy, and information on normal immune response and disorders. Each of the major autoimmune disorders is discussed by researchers and clinical investigators experienced in dealing with patients. Chapters emphasize the immunologic basis of the disease as well as the use of immunologic diagnostic methods and treatments. The book also covers several cross-cutting issues related to the recognition and treatment of autoimmune diseases, including chapters on the measurement of autoantibodies and T cells, the use of biomarkers as early predictors of disease, and new methods of treatment. - Gives a thorough and important overview on the entire field, framing individual disease chapters with information that compares and contrasts each disorder and its therapy - Provides thorough, up-to-date information on specific diseases, along with clinical applications in an easily found reference for clinicians and researchers interested in certain diseases - Keeps readers abreast of current trends and emerging areas in the field - Ensures that content is not only up-to-date, but applicable and relevant - Includes new, updated chapters that emphasize hot topics in the field, e.g., research on auto inflammatory diseases and autoimmune responses following cancer immunotherapy

'A gripping and sobering reminder of how much we are all governed by our genetic inheritance. So much for free will.'The Mail on SundayStress, obesity, poor mental health, drug addiction, bowel diseases, violence and fake news; a stark checklist of modern world problems and every one of them is an echo of our evolutionary past.In Unfit for Purpose, biologist and broadcaster Adam Hart explores the mismatch between our fundamental biology and the modern world we have created. In each chapter Adam reveals the many ways in which biological adaptations that evolved to help us survive and thrive now work against us. For example, in the modern world stress is a killer but how did'fight or flight'instincts turn from life-savers to life-takers? Obesity is a disease now but is it also just a side-effect of our evolutionary past? Whether it's the derailing of microbes in our gut, the rise of gluten and lactose intolerance, problems of social media or drug addiction, we always seem to have one foot in the modern world and the other firmly in our evolutionary past. Adam explores science, archaeology, medicine, genetics, sociology and more, to show how, in a modern world of our own making, we find ourselves'unfit for purpose'. But all is not lost! In unpicking the causes of our current woes, he unearths some secrets of evolutionarily informed treatments that will change the way we think about ourselves and our future.

Trends in Wheat and Bread Making provides a comprehensive look at the state-of-the-art in bread making from ingredient to shelf-life, with a focus on the impact of processing on the nutritional value and consumer acceptability of this global staple. The book also includes chapters on new breads and bakery products fortified with plant-processing-by-products and/or natural antioxidants, and explores efforts to improve biotechnological processes and fermentation for bread making. It is an excellent resource for researchers, industry professionals and enterprises hoping to produce enhanced bread products through processing-related nutritional and quality improvements. - Addresses gluten free products, organic farming and production techniques, enzymatic and biotechnological techniques, fortification of breads with plant by-products, and phenol-rich substrates - Fills the gap in current resources, focusing on the application of new technologies for processing practices - Provides a guide to industrial and commercialized applications of innovative breadmaking

A Practical Approach to Neurology for the Small Animal Practitioner provides veterinary practitioners and students with a comprehensive guide to diagnosing and treating neurological cases in small animal practice. Covering the most important considerations for the general practitioner, the book includes chapters on clinical history taking, a ‘stress-free'approach to the neurological examination, the most common neurological presentations in general practice, neurological emergencies, and more. It is easy to read, packed with practical hints and tips, and the information is presented using tables and bulleted lists, with accompanying images and videos to illustrate the concepts. A Practical Approach to Neurology for the Small Animal Practitioner is ideal for newly qualified vets, veterinary students, and experienced vets seeking a refresher.

Quinoa (Chenopodium quinoa Willd) is a pseudocereal of Andean origin that is becoming more and more popular in Europe, Asia and the United States of America because it is a good source of different nutrients, rich in antioxidant compounds and it offers an alternative to classical cereals in celiac diet because its seeds are gluten-free. Concerning its employment in food application, quinoa-derived products have been successfully employed in the preparation of different foods as fat/cream substitutes and to enhance the quality of baked foods. This book aims to review recent advances in the quinoa plant cultivation as well as the nutritional properties and effects on human health of quinoa-derived products. Chapter One focuses on the morphophenological evaluation of different quinoa accessions collected all over the world and their agronomical performances tested both in the experimental field and open field trials. In Chapter Two, the authors provide a description of the phenology, made on three different growing seasons, of a wide group of quinoa varieties, collected in different environments, in field conditions at the Peruvian central coast. Chapter Three evaluates the antioxidative capacity and phenolic compounds content in the aerial part of the quinoa plant during its growth cycle in six progressive morphological stages from the early vegetative to the grain fill stage. In Chapter Four, the authors determined the nutritional value and content of some bioactive compounds in different quinoa (Chenopodium quinoa Willd.), kañiwa (Chenopodium pallidicaule Aellen) and kiwicha (Amaranthus caudatus L.) ecotypes collected in Peru. Chapter Five describes the potential use of quinoa seed and plant in animal nutrition. The authors of Chapter Six described the employment of the fermentation process to improve technological, nutritional and sensory quality of quinoa in order to obtain the fortification of conventional or novel foods. The aim of chapter seven is to review the available studies on the use of quinoa as a bread making ingredient. In Chapter Eight, the authors examined the quality characteristics of cereal-based foods enriched with quinoa flour and inulin with a different degree of polymerization in order to obtain new fortified breads and pasta with lowering glicemic index effect. Chapter Nine evaluates studies carried out to develop healthier gluten-free products, considering sensory and technological aspects of quality to help promoting the quality of life for people who need to follow a gluten-free diet. Chapter Ten critically reviews studies on the use of quinoa as a milk substitute on dairy products since it presents a good source of protein with a low glycemic index. In Chapter Eleven authors proposed a novel icing system based on the use of an aqueous/ethanolic saponin-free quinoa extract to obtain improvement in the quality of both lean and fatty fish species during commercialization under chilled conditions. Finally, nutritional implications of quinoa intake have been revised in Chapter Twelve.

The Handbook of Social Policy and Development makes a groundbreaking, coherent case for enhancing collaboration between social policy and development. With wide ranging chapters, it discusses a myriad of ways in which this can be done, exploring both academic and practical activities. As the conventional distinction between'developed'and'developing'countries becomes increasingly blurred, this Handbook explores how collaboration between social policy and development is needed to meet global social needs.With contributions from leading experts in both social policy and development studies, this Handbook analyses the complexities of integrating social policy and development studies. Examining a diverse and comprehensive range of countries and case studies that highlight ways to improve this integration, contributors deal with critical debates, covering a wide range of services, programmes, providers and policy sectors.The Handbook of Social Policy and Development is an invaluable introduction to the subject for students of social policy and development studies. Its comprehensive approach also makes it a valuable reference for researchers and specialists in the field. Contributors include: L. Alfers, A. Barrientos, J. Beall, A. Datta, H. Dean, K. Falkenberg, R. Jolkonnen, D. Kiwan, H.-j. Kwon, J. Lee, A. Lombard, F. Lund, P. Mader, J. Midgley, L. Patel, M. Pawar, M. Rogan, R. Surender, M. Terano, M. Urbina-Ferretjans, A. Virk, N. Yeates

The revised fourth edition of Evidence-Based Gastroenterology and Hepatology continues to provide the most current, evidence-based information for determining the appropriate medical and surgical options for screening for, diagnosing, and treating gastrointestinal conditions. With contributions from an international team of leading experts in the field, the 4th edition includes practical recommendations for the care of individual patients based on the latest scientific evidence.

Thorough Overview Identifies and Addresses Critical Gaps in the Treatment of Several Chronic Diseases With increasing numbers of patients suffering from Immune-Mediated Inflammatory Diseases (IMIDs), and with the increasing reliance on biopharmaceuticals to treat them, it is imperative that researchers and medical practitioners have a thorough understanding of the absorption, distribution, metabolism and excretion (ADME) of therapeutic proteins as well as translational pharmacokinetic/pharmacodynamic (PK/PD) modeling for them. This comprehensive volume answers that need to be addressed. Featuring eighteen chapters from world-renowned experts and opinion leaders in pharmacology, translational medicine and immunology, editors Honghui Zhou and Diane Mould have curated a much-needed collection of research on the advanced applications of pharmacometrics and systems pharmacology to the development of biotherapeutics and individualized treatment strategies for the treatment of IMIDs. Authors discuss the pathophysiology of autoimmune diseases in addition to both theoretical and practical aspects of quantitative pharmacology for therapeutic proteins, current translational medicine research methodologies and novel thinking in treatment paradigm strategies for IMIDs. Other notable features include: • Contributions from well-known authors representing leading academic research centers, specialized contract research organizations and pharmaceutical industries whose pipelines include therapeutic proteins • Chapters on a wide range of topics (e.g., pathophysiology of autoimmune diseases, biomarkers in ulcerative colitis, model-based meta-analysis use in the development of therapeutic proteins) • Case studies of applying quantitative pharmacology approaches to guiding therapeutic protein drug development in IMIDs such as psoriasis, inflammatory bowel disease, multiple sclerosis and lupus Zhou and Mould's timely contribution to the critical study of biopharmaceuticals is a valuable resource for any academic and industry researcher working in pharmacokinetics, pharmacology, biochemistry, or biotechnology as well as the many clinicians seeking the safest and most effective treatments for patients dealing with chronic immune disorders.

Encyclopedia of Biomedical Gerontology, Three Volume Set presents a wide range of topics, ranging from what happens in the body during aging, the reasons and mechanisms relating to those age-related changes, and their clinical, psychological and social modulators and determinants. The book covers the biological and medical aspects of gerontology within the general framework of the biological basis of assessing age, biological mechanisms of aging, age-related changes in biological systems, human age-related diseases, the biomedical practicality and impracticality of interventions, and finally, the ethics of intervention. - Provides a'one-stop'resource to information written by world-leading scholars in the field of biomedical gerontology - Fills a critical gap of information in a field that has seen significant progress in the last 10 years

Advances in Clinical Chemistry, Volume 91, the latest release in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians and research scientists. The serial discusses the latest and most up-to-date technologies related to the field of clinical chemistry, providing the benchmark for novel analytical approaches in the clinical laboratory. - Provides the most up-to-date technologies in clinical chemistry and clinical laboratory science - Authored by world renowned clinical laboratory scientists, physicians and research scientists - Presents the international benchmark for novel analytical approaches in the clinical laboratory

The Role of Alternative and Innovative Food Ingredients and Products in Consumer Wellness provides a guide for innovative food ingredients and food products. The book covers consumer wellness as it relates to food ingredients and functional foods, alternative ingredients, food products fortified with extracts derived from food processing by-products, food products based on Omega-3 polyunsaturated fatty acids and their health effects, selected superfoods and related super diets, edible insects, microalgae as health ingredients for functional foods and spirulina related products, fruit-based functional foods, pro- and pre-biotics, gluten-free products, and bioaromas. Food scientists, food technologists and nutrition researchers working on food applications and food processing will find this book extremely useful. In addition, those interested in the development of innovative products and functional foods will also benefit from this reference, as will students who study food chemistry, food science, technology, and food processing in postgraduate programs. - Connects integrally new and reconsidered food ingredients with innovative food products - Addresses consumer wellness as it relates to food ingredients and functional foods - Analyzes food products and processes with the highest market potential

With a foreword written by Professor Ludwig Narziss—one of the world's most notable brewing scientists—the Handbook of Brewing, Third Edition, as it has for two previous editions, provides the essential information for those who are involved or interested in the brewing industry.The book simultaneously introduces the basics—such as the biochemistry and microbiology of brewing processes—and also deals with the necessities associated with a brewery, which are steadily increasing due to legislation, energy priorities, environmental issues, and the pressures to reduce costs. Written by an international team of experts recognized for their contributions to brewing science and technology, it also explains how massive improvements in computer power and automation have modernized the brewhouse, while developments in biotechnology have steadily improved brewing efficiency, beer quality, and shelf life.

Differential diagnosis is at its most accurate and efficient when clinical presentation and histopathological features are considered in correlation with one another. With this being so, the expert team behind this atlas has integrated both perspectives to create an innovative and essential resource for all those involved with the diagnosis of tumors, cysts, and nevi. Almost 1,400 full-color images clearly illustrate common patterns and variants of tumorous lesions of the skin and are helpfully contextualized by concise, straightforward descriptions of key features and diagnostic clues. Whether they are aspiring or experienced practitioners, dermatologists and pathologists of all levels will find this an insightful and practically applicable addition to their bookshelf. Its far-reaching and easy-to-navigate coverage of relevant diseases of the skin provides trainees with an excellent grounding in the area, while practicing specialists may benefit from its use as a tool for the differential diagnoses of borderline cases. Atlas of Dermatopathology: Tumors, Nevi, and Cysts offers a uniquely balanced, clear, and comprehensive guide to what can be a difficult process, and will be of tremendous assistance tostudents, dermatologists, dermatopathologists, and pathologists everywhere.

This book brings together world experts in the field of Functional Gastrointestinal Disorders (FGIDs) who practice an integrated and holistic approach in their care for patients to provide an up-to-date and comprehensive evaluation of a range of issues associated with the biopsychosocial treatment of FGIDs. Examining topics such as neurological and biological aspects of FGIDs, common concerns faced in relation to diagnosis, and ongoing medical decisions and interventions, each chapter provides crucial practical recommendations, as well as future directions of psychosocial work in multi-team environments.Functional Gastrointestinal Disorders considers individual conditions in detail, including the current Rome IV diagnostic criteria for FGIDs required to make a positive diagnosis, the role of psychological and other biopsychosocial and biofeedback aspects of treatment, and general recommendations with regard to diet and medications. Each chapter also provides an up-to-date consolidation and evaluation of the current literature as well as practical recommendations, which can then be applied by the reader in their own interaction with FGID patients. Topics covered include: the common concerns and issues faced by individuals with FGIDs in relation to pre-and post-diagnosis, ongoing medical decisions and interventions review of current evidence-based biopsychosocial treatment practices for each FGID condition the differences and challenges associated with FGIDs across individual life stages special topics such as the relationship with eating disorders and the role of psychotropic medications modern patient centred initiatives such as patient empowerment, distance and e-therapies the future challenges facing FGID treatment. Throughout the entire book, common themes and practical recommendations are described. Functional Gastrointestinal Disorders, has broad applicability across multiple spheres, including treatment, research and teaching and is accessible to those working in gastroenterology and primary care alike.

A unique question-and-answer book for surgical residents and trainees that covers all surgical aspects of critical care and acute or emergency medicine This is a comprehensive, one-of-a-kind question-and-answer text for medical professionals and apprentices concentrating on the growing subspecialty of surgery in critical care and emergency surgery. Covering all surgical aspects of critical care and acute or emergency surgery, it is an ideal learning and review text for surgical residents and trainees who care for these patients and those taking the Surgical Critical Care Board Examination. Edited by highly experienced professionals, and written in an engaging style, Surgical Critical Care and Emergency Surgery: Clinical Questions and Answers focuses exclusively on the unique problems and complexity of illnesses of the critically ill and injured surgical patient, and covers the specialist daily care such patients require. It reflects the latest advances in medical knowledge and technology, and includes fully revised and updated questions throughout, with additional topics addressed in a new companion website. Unique question-and-answer book on the growing specialty of critical care and acute surgery Ideal for US boards candidates Covers trauma and burns as well as critical care 8 page full-color insert showing high quality surgical photos to aid study Supplementary website including additional questions Surgical Critical Care and Emergency Surgery, Second Edition is an excellent resource for medical students, residents, fellows, and surgeons, as well as those in non-surgical specialties.

International Review of Cell and Molecular Biology. Volume 336 reviews and details current advances in cell and molecular biology. The IRCMB series has a worldwide readership, maintaining a high standard by publishing invited articles on important and timely topics that are authored by prominent cell and molecular biologists. This updated volume includes specific chapters on Membrane trafficking in autophagy, Targeting the metabolism of leukemic cells, Autophagic flux in Alzheimer's disease, Transcriptional alterations associated with celiac disease, and the Regulation of antitumor immunity by IDO1, amongst other timely topics. The articles published in IRCMB have a high impact and an average cited half-life of 9 years. This great resource ranks high amongst scientific journals dealing with cell biology. - Publishes only invited review articles on selected topics - Authored by established and active cell and molecular biologists, drawn from international sources - Offers a wide range of perspectives on specific subjects

Proteins in Food Processing, Second Edition, reviews how proteins may be used to enhance the nutritional, textural and other qualities of food products. After two introductory chapters, the book discusses sources of proteins, examining the caseins, whey, muscle and soy proteins, and proteins from oil-producing plants, cereals and seaweed. Part Two illustrates the analysis and modification of proteins, with chapters on testing protein functionality, modeling protein behavior, extracting and purifying proteins and reducing their allergenicity. A final group of chapters delves into the functional value of proteins and how they are used as additives in foods. - Completely revised and updated with new developments on all food protein analysis and applications, such as alternative proteins sources, proteins as emulsifiers, proteins in nanotechnology and egg proteins - Reviews the wide range of protein sources available - Examines ways of modifying protein sources - Discusses the use of proteins to enhance the nutritional, textural and other qualities of food products

The full text downloaded to your computer With eBooks you can: search for key concepts, words and phrases make highlights and notes as you study share your notes with friends eBooks are downloaded to your computer and accessible either offline through the Bookshelf (available as a free download), available online and also via the iPad and Android apps. Upon purchase, you'll gain instant access to this eBook. Time limit The eBooks products do not have an expiry date. You will continue to access your digital ebook products whilst you have your Bookshelf installed. Principles of Pathophysiology is the first ground-up Australian text in pathophysiology. Moving away from the traditional approach, the text focuses on the balance of pathophysiology and clinical adaptation, which is often combined with pharmacology. This text helps learners to understand complex pathophysiological concepts through its accessible format and strong integration of science with clinical practice. Samples Download the detailed table of contents to Principles of Pathophysiology Preview a sample chapter from Principles of Pathophysiology