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The Teddy Bear Book is the only reference of its kind that focuses on the unique issues that healthcare professionals face when using injectable medications in children, such as limited fluid volumes, maximum concentrations, and rates of administration. The 12th Edition features more than 270 updated monographs (including over 40 monographs new to this edition) that cover the following areas: Safety issues Infusion-related cautions Dosages and conditions requiring dosage adjustments Contraindications and warnings Adverse drug effects Preparation and compatibility Bolus, intermittent, and continuous IV administration Monitoring

You've got this! Good enough is a cookbook, but it's as much about the healing process of cooking as it is about delicious recipes. It's about acknowledging the fears and anxieties many of us have when we get in the kitchen, then learning to let them go in the sensory experience of working with food. It's about slowing down, honoring the beautiful act of feeding yourself and your loved ones, and releasing the worries about whether what you've made is good enough. It is. A generous mix of essays, stories, and nearly 100 dazzling recipes, Good Enough is a deeply personal cookbook. It's subject is more than Smoky Honey Shrimp Tacos with Spicy Fennel Slaw or Sticky Toffee Cookies; ultimately it's about learning to love and accept yourself, in and out of the kitchen.

To promote effectiveness and minimize possible toxicity, the dosage of certain medications must be adjusted in persons with compromised kidney function. Failure to enjoin appropriate dosage adjustments in patients with abnormal or rapidly changing kidney function continues to lead to reports of drug toxicity involving a broad array of renally eliminated medications.This updated edition captures nearly 200 new drugs that have been approved by the FDA since the initial publication of Renal Pharmacotherapy. It also covers new evidence that has emerged regarding the need to adjust dosage of certain older medications that are eliminated by the kidneys. Additionally, it presents new data that are being continuously derived in the areas of patient-specific dose individualization for drugs of all types.Comprehensive, convenient, and evidence-based, this reference closes several identified knowledge gaps and will continue to be the leading collection of dosage recommendations for patients with compromised kidney function.

Textbook of Small Animal Emergency Medicine offers an in-depth understanding of emergency disease processes and the underlying rationale for the diagnosis, treatment, monitoring, and prognosis for these conditions in small animals. A comprehensive reference on a major topic in veterinary medicine The only book in this discipline to cover the pathophysiology of disease in depth Edited by four respected experts in veterinary emergency medicine A core text for those studying for specialty examinations Includes access to a website with video clips, additional figures, and the figures from the book in PowerPoint Textbook of Small Animal Emergency Medicine offers an in-depth understanding of emergency disease processes and the underlying rationale for the diagnosis, treatment, monitoring, and prognosis for these conditions in small animals.

Pediatric Injectable Drugs, also known as “The Teddy Bear Book,” is one of the ASHP's most recognized and trusted resources dedicated to helping pharmacists treat pediatric patients with injectable drugs. For more than 20 years, pharmacists and hospital pediatric teams have looked to Pediatric Injectable Drugs (The Teddy Bear Book) for the most comprehensive research-based information on pediatric intravenous infusions. Now for the first time since 2013, a new edition of this trusted resource is available! The “Teddy Bear Book”, is the only reference of its kind that focuses on the unique issues that pediatric practitioners face when dealing with pediatric injectable drugs, such as limited fluid amounts, limited intravenous sites, and maximum doses. The updated edition of this comprehensive resource by respected editors Stephanie J. Phelps, PharmD, BCPS, Kelley R. Lee, PharmD, Amanda Jill Thompson, PharmD, and Tracy M. Hagemann, PharmD, FCCP, includes 15 new monographs and updates based on the latest evidence-backed literature.

CONGENITAL AND PERINATAL INFECTIONS provides a concise and clinically-oriented primer on the congenital and perinatal infections likely to present in clinical practice. Written with the busy clinician in mind, it combines easy accessibility with state-of-the-art information on the epidemiology, pathogenesis, clinical manifestations, diagnosis, treatment, and prevention of congenital and perinatal infections. Eschewing the notion that congenital and perinatal infections only encompass agents from the TORCH group of pathogens, this volume offers comprehensive information on the spectrum of viral, bacterial, and parasitic infections that can manifest in mother or child. Combined with its brevity and emphasis on clinical management, CONGENITAL AND PERINATAL INFECTIONS is a definitive new guide to understanding this challenging group of infections.

This book provides unique insights into the issues that drive modified dosing regimens for antibiotics in the critically ill. Leading international authors provide their commentary alongside a summary of existing evidence on how to effectively dose antibiotics. Severe infection frequently necessitates admission to the intensive care unit (ICU). Equally, nosocomial sepsis often complicates the clinical course in ICU. Early, appropriate application of antibiotic therapy remains a cornerstone of effective management. However, this is challenging in the critical care environment, given the significant changes in patient physiology and organ function frequently encountered. Being cognisant of these factors, prescribers need to consider modified dosing regimens, not only to ensure adequate drug exposure, and therefore the greatest chance of clinical cure, but also to avoid encouraging drug resistance.

The book is an English translation of an award winning German book. The history of social and religious encounter in 18th century South India is narrated through fascinating biographies and day to day lives of Indian workers in the Tranquebar Mission (1706-1845). The book challenges the notion that Christianity in colonial India was basically imposed from the outside. Liebau maintains that significant contributions were made by the local converts and mission co-workers who played an important role in the Tranquebar Mission.

This text outlines the importance of biopsychosocial factors in improving medical care, and illustrates evidence-based, state-of-the-art interventions for patients with a variety of medical conditions. Each chapter is focused on a particular health concern or illness, which is described both in terms of prevalence and frequent psychological and psychiatric comorbidities that may present to clinicians working with these populations. Consistent with evidence-based care, information on the efficacy of the treatments being described is presented to support their continued use. To accommodate the needs of clinicians, we describe population specific approaches to treatment, including goal settings, modules and skills as well as strategies to assess and monitor progress. To facilitate learning, each chapter contains one or more case examples that explicate the skills described to convey change within a behavioral medicine protocol. Each chapter also includes resources in the form ofbooks and websites to gain additional knowledge and detail as needed. Authors are experts in the field of each chapter, ensuring that information presented is recent and of high quality.

Dr. O'Malley is a well-known nurse researcer in the area of Hemaotology, and she has assembled top experts to write about the most important hemtaologic issues in critical care. The issue has articles devoted to the following topics: Cord blood banking; Leukemia and Lymphomas; Sickle Cell; Anticoagulants; Aplastic anemia & MDS; Hereditary Hemochromatosis and Pernicious Anemia; Hemophilia; Blood book: cells, products, transfusion; Anemia; Multiple Myeloma; DIC; and The lived experience of anemia without a cause. Nurses will come away with the clinical information they need to improve patient outcomes in the critical care setting.

As the number of patients undergoing hematotopoietic or solid organ transplantation increases, a deep understanding of the field of transplant infectious diseases grows increasingly vital. With its extensively revised and updated review of surgical infections, treatment, prevention, and practice, this book is the ultimate guide to advances in the field of transplant infections that are rapidly implemented into practice both in diagnostic technologies, new therapies, new transplant practices, and challenges such as the threat of multiresistant bacteria and the increasing use of transplantation in the developing parts of the world. Written by experts in their fields, this book is the only comprehensive source of cutting-edge information on transplant infections and has been a trusted guide to medical professionals worldwide for nearly two decades.Transplant Infections is of paramount value to infectious disease specialists, transplant physicians, medical students, fellows, residents, and all medical professionals working with surgical patients.

The classic reference work that provides annually updated information on the countries of the world.

Meyler's Side Effects of Drugs: The International Encyclopedia of Adverse Drug Reactions and Interactions, Sixteenth Edition, Seven Volume Set builds on the success of the 15 previous editions, providing an extensively reorganized and expanded resource that now comprises more than 1,500 individual drug articles with the most complete coverage of adverse reactions and interactions found anywhere. Each article contains detailed and authoritative information about the adverse effects of each drug, with comprehensive references to the primary literature, making this a must–have reference work for any academic or medical library, pharmacologist, regulatory organization, hospital dispensary, or pharmaceutical company. The online version of the book provides an unparalleled depth of coverage and functionality by offering convenient desktop access and enhanced features such as increased searchability, extensive internal cross-linking, and fully downloadable and printable full-text, HTML or PDF articles. - Enhanced encyclopedic format with drug monographs now organized alphabetically - Completely expanded coverage of each drug, with more than 1,500 drug articles and information on adverse reactions and interactions - Clearer, systematic organization of information for easier reading, including case histories to provide perspective on each listing - Extensive bibliography with over 40,000 references - A must–have reference work for any academic or medical library, pharmacologist, regulatory organization, hospital dispensary, or pharmaceutical company

The world population has increased dramatically in the past century, generating a concern for progressive and sustainable food production. It is expected to further increase by 1.3 billion in 2030 and by 2.5 billion in 2050, reaching 9.7 billion. To provide food security to this growing population, the world food production may need to increase by 60-110%. Biotic and abiotic stresses are major threat to plant growth and halt them from reaching their full genetic potential and ultimately limiting their productivity. High yield varieties are confronted by various stresses which lead to huge loss in production and productivity. Understanding the mechanisms involved in the response of plants to adverse environmental conditions is the first step in the generation of crops with higher tolerance to these stresses. This book provides a broad overview of biotic and abiotic stresses, their mechanisms and different strategies to improve stress tolerance in crop plants. The book provides discussion on following topics:? Reactive oxygen species: generation, scavenging, and their role in cell signalling in plants.? Calcium mediated pathogen defence system? Transcription factors in abiotic stress tolerance? MAPK signalling modules in stress? Plant hormones and stress? Plant stress regulation? Salinity stress in plants? Recent advances in Populus euphratica in relation to salinity stress? Chilling stress tolerance in plants: physiology and mechanisms? Heat stress response in plants? Drought tolerance in crops? Aluminium stress in crop plants? An insight into plant growth and metabolism in relation to hexavalent chromium? Waterlogging stress: an overview? Anthropogenic induced stress and its impact on plants? Breeding for abiotic stress tolerance in crop plants? Breeding for resistance to biotic stresses in plants? Transgenic approaches for abiotic stress tolerance in plants? Transgenic approaches for biotic stress tolerance in plants? Advances in biotechnology for development of submergence tolerance in crops? Proteomic perspectives on understanding plant stress response? Role of molecular markers for improvement of stress tolerance in crops

A fonte mais respeitada e abrangente de trauma Descreve o passo a passo do diagnóstico e tratamento dos traumas bucomaxilofaciais e lesões associadas. A quarta edição de Trauma Bucomaxilofacial, além de apresentar o tratamento cirúrgico do trauma de cabeça e pescoço, abrangerá, em especial, a conduta completa nas injúrias traumáticas, a avaliação sistemática do paciente traumatizado e considerações especiais associadas ao manejo do paciente com trauma maxilofacial. A novidade desta edição são as mais de 700 ilustrações coloridas que mostram os detalhes dos traumas e seus tratamentos. Editada pelo especialista em trauma de cabeça e pescoço Dr. Raymond J. Fonseca, com a parceria de mais de 80 colaboradores renomados, essa referência fornece toda a informação necessária para oferecer o melhor tratamento possível para o paciente com trauma maxilofacial. Novidades desta edição • Conteúdo que re ete as tendências atuais e as técnicas mais recentes no tratamento do paciente traumatizado. • Novo design e mais de 700 ilustrações coloridas que ressaltam as áreas clínicas e mostram os detalhes das lesões e seus tratamentos. • Novo formato simpli- cado em um só volume, que é fácil de carregar, permitindo acesso mais fácil à informação. • Novo capítulo sobre Cirurgia Minimamente Invasiva no Trauma Bucomaxilofacial (Capítulo 34). • Capítulos especiais e fáceis de serem compreendidos, embasados na literatura atual, que incluem tópicos sobre avanços na cirurgia do trauma maxilofacial, trauma não penetrante de tórax, resposta metabólica ao trauma, prótese maxilofacial e impacto social do trauma maxilofacial. • Abordagem de temas emergentes, como trauma por arma de fogo, lesão neurológica (a principal causa de morte decorrente do trauma), cicatrização tecidual, manejo das vias aéreas, choque e fraturas nasais, reforçando a importância do trabalho em equipe com neurologistas, anestesiologistas, ortopedistas e outras especialidades.

Small Animal Distal Limb Injuries provide the small and mixed animal practitioner with a definitive but practical, step-by-step guide to the management of soft tissue, orthopedic and athletic injuries of the distal limbs in dogs and cats.Includes specific coverage of injuries that occur from the carpal/tarsal areas to the digits of dogs and cats. A

This is the first comprehensive selection from the correspondence of the iconic and beloved Langston Hughes. It offers a life in letters that showcases his many struggles as well as his memorable achievements. Arranged by decade and linked by expert commentary, the volume guides us through Hughes's journey in all its aspects: personal, political, practical, and—above all—literary. His letters range from those written to family members, notably his father (who opposed Langston's literary ambitions), and to friends, fellow artists, critics, and readers who sought him out by mail. These figures include personalities such as Carl Van Vechten, Blanche Knopf, Zora Neale Hurston, Arna Bontemps, Vachel Lindsay, Ezra Pound, Richard Wright, Kurt Weill, Carl Sandburg, Gwendolyn Brooks, James Baldwin, Martin Luther King, Jr., Alice Walker, Amiri Baraka, and Muhammad Ali. The letters tell the story of a determined poet precociously finding his mature voice; struggling to realize his literary goals in an environment generally hostile to blacks; reaching out bravely to the young and challenging them to aspire beyond the bonds of segregation; using his artistic prestige to serve the disenfranchised and the cause of social justice; irrepressibly laughing at the world despite its quirks and humiliations. Venturing bravely on what he called the “big sea” of life, Hughes made his way forward always aware that his only hope of self-fulfillment and a sense of personal integrity lay in diligently pursuing his literary vocation. Hughes's voice in these pages, enhanced by photographs and quotations from his poetry, allows us to know him intimately and gives us an unusually rich picture of this generous, visionary, gratifyingly good man who was also a genius of modern American letters.

Trauma is the leading cause of death among people under the age of 40 and it ranks third for all age groups. Still, relatively few clinicians specialize in trauma and training is often obtained through experience. The number of trauma patients is expected to continue to grow as pre-hospital care continues to advance. As well, hospitals increasingly see trauma treatment, which requires no pre-approval, as a good source of revenue. Given these developments, the number of opportunities for specialists trained in trauma, including anesthesiologists and critical care physicians, will expand in the years ahead. This book addresses the need for an up-to-date, comprehensive and clinically focused volume for practitioners and trainees in trauma anesthesia and critical care. It is organized by organ system. The editor is an attending physician at a major urban hospital center recognized worldwide for its outstanding emergency medical services including trauma care and is recruiting leading trauma anesthesiologists to contribute. Anesthesiologists, pain medicine physicians, critical care physicians and trainees are the target audience.

Completely revised and updated, Human Herpesviruses HHV-6A, HHV-6B & HHV-7, Third Edition, delivers a contemporary and thorough review of HHV-6, beginning with foundational explorations of classification, molecular biology, and chromosomal integration of the virus, through to clinical details, including pathologic features of infection, and clinical effects on various organ systems. The work now includes coverage of HHV-7, a virus that remains underestimated in transplant reactivation, seizures, and encephalitis. The book examines the role of HHV-6 in myriad diseases, including cognitive disorders following bone marrow transplant, mesial temporal lobe epilepsy, multiple sclerosis, autoimmune disease, encephalitis, Hodgkin's disease lymphoma (HHV-6B), and glioma (HHV-6A). Descriptions of current and novel molecular and serological diagnostic assays, along with detailed protocols, are included to aid researchers and clinicians in discriminating potential false positives originating from chromosomally integrated HHV-6, and in differentiating between active and latent infection. Human Herpesviruses HHV-6A, HHV-6B & HHV-7, Third Edition is a valuable reference for both clinical and basic scientists, including epidemiologists, virologists, practicing clinicians, infectious disease specialists, pathologists, and all scientists entering the field of herpes virus research. The work is a practical and thorough resource for a foundational understanding of HHV-6 and HHV-7, while providing a cutting-edge translational and clinical reference to those looking to understand and diagnose associated viral diseases. - Delivers the latest molecular diagnostic tests, the present-day gold standard for monitoring HHV-6 - Provides expert analysis of T-cell immune response against HHV-6 - Presents tools for differential diagnosis in HHV-6 viral infections - Includes new information on the previously-largely-unknown biological consequences of ciHHV-6 - Offers coverage of new discoveries relating to HHV-7

Against the backdrop of the environmental setting of the subequatorial NE Pacific abyssal plain, the book will characterise the meiobenthos as an ecological category in the deep sea and introduce research lines meiobenthic studies are applied to, including environmental assessments of human-induced disturbance of the deep seafloor. It will proceed to present an overview of the current knowledge on the meiobenthos of the area of concern and will discuss general considerations regarding the use of meiobenthos as indicator of seafloor disturbance. It will address the question of deep-sea mineral resources development versus benthic communities and will present an overview of field studies ('experiments') aimed at assessing the magnitude of potential impact associated with seafloor resources development (polymetallic nodule mining in particular) in the Pacific.

Rely on Rosen's Emergency Medicine for the latest answers on every facet of emergency medicine practice. For decades, this medical reference book has set the standard in emergency medicine, offering unparalleled comprehensiveness, clarity, and authority - to help you put the latest and best knowledge to work for your patients in the ER.Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Compatible with Kindle®, nook®, and other popular devices.Practice confidently with easily actionable, dependable guidance on the entire breadth of emergency medicine topics.Get expert guidance on how to approach specific clinical presentations in the ER. The'Cardinal Presentations Section'provides quick and easy reference to differential diagnosis and directed testing for fever in the adult patient; dizziness and vertigo; chest pain; and over 20 other frequently seen presentations in the emergency department. Effectively apply the newest emergency medicine techniques and approaches, including evidence-based therapies for shock; high-cost imaging; evaluation and resuscitation of the trauma patient; cardiovascular emergencies; evaluation and risk stratification for transient ischemic attack (TIA) patients; and much more. Locate the answers you need quickly thanks to a user-friendly, full-color design, complete with more illustrations than ever before.Access the complete contents on the go from your laptop or mobile device at Expert Consult, fully searchable, with links to PubMed.

This book presents a detailed overview of the development of new viral vector-based vaccines before discussing two major applications: preventive vaccines for infectious diseases and therapeutic cancer vaccines. Viral vector-based vaccines hold a great potential for development into successful pharmaceutical products and several examples at the advanced pre-clinical or clinical stage are presented. Nevertheless, the most efforts were focused on novel and very innovative technologies for new generation of vector-based vaccines. Furthermore, specific topics such as delivery and adjuvant and protection strategies for cell-mediated-based vaccines are presented. Given its scope, the book is a “must read” for all those involved in vaccine development, both in academia and industrial vaccine development.

Die Antinozizeption im Arbeitsrahmen des physiologischen Ablaufs von Nozitransduktion bis Noziperzeption wird hier erstmalig in Buchform dargestellt. Dieser Rahmen erlaubt die logische Darstellung einer möglichen pharmakologischen Beeinflussung der Antinozizeption. Das gut durchstrukturierte Buch erläutert die Wirkungsweise der zentralwirksamen und antipyretischen Analgetika. Sämtliche in der Klinik einsetzbaren Wirkstoffe werden standardisiert in Bezug auf Dynamik, Kinetik und Klinik dargestellt. Ein ausführliches Verzeichnis der relevanten Fachliteratur und ein lexikonartiges Glossar runden das Werk ab.

This book is the first to approach the field of congestive heart failure as a true subspecialty of cardiology and cardiovascular surgery. The text discusses the entire field of congestive heart failure: the basic pathophysiologic mechanisms; the underlying diseases; the effects of heart failure on the remainder of circulation; the mechanisms and results of pharmacologic therapy; the multiple surgical and multidisciplinary approaches to end-stage heart disease; and the ultimate prognosis of congestive heart failure in all of the areas of heart failure management. Thus, this text uniquely puts into perspective all of the features of congestive heart failure and its management for the cardiologist, cardiovascular surgeon, and general internist.

Now completely up to date to meet the needs of today's pediatric nurses, Mary Fran Hazinski's Nursing Care of the Critically Ill Child, 3rd Edition, remains the foundational text of pediatric critical care nursing. Known for its outstanding organization and clear descriptions, this comprehensive reference details the unique care required for critically ill children with thorough discussions of physiology, pathophysiology, pharmacology, collaborative management, and nursing management. Ten new chapters, new advanced practice content, and new nurse contributors and reviewers ensure that this classic text continues to be the essential resource for the care of critically ill children. - Details differences in caring for critically ill children as compared with caring for adults: how to modify assessment procedures, consider aspects of psychosocial development, and examine developmental aspects of various body systems. - Provides comprehensive coverage of physiology, pathophysiology, pharmacology, and nursing management related to care of the critically ill child. - Includes detailed Nursing Care Plans for select disorders. - Contains helpful appendices such as pediatric drug dosages, central venous catheter care, and pediatric fluid requirements. - Features Evolve online resources with additional content for further study of related topics, including tables for ease of recollection of material and additional references. - Contains 10 all-new chapters, including Pharmacokinetics and Pharmacodynamics; Shock, Cardiac Arrest, and Resuscitation; Mechanical Support of Cardiopulmonary Function; Fluid, Electrolyte, and Endocrine Problems; Immunology and Infectious Disorders; Transplantation and Organ Donation; Toxicology/Poisonings; Fundamentals of Quality Improvement and Patient Safety; Clinical Informatics; and Ethical Issues in Pediatric Critical Care - Features nurse contributors and reviewers for every chapter, making this edition a truly collaborative text. - Provides information vital to the advanced practice nurse, such as assessment tools and severity of illness management. - Includes numerous Pearls that highlight practical wisdom from experts in pediatric critical care nursing.

••Selected for Doody's Core Titles® 2024 in Trauma Surgery•• Describing the diagnosis and management of maxillofacial and associated traumatic injuries step by step, Oral and Maxillofacial Trauma, 4th Edition takes you beyond the surgical management of head and neck trauma to cover the general management of traumatic injuries, systemic evaluation of the trauma patient, and special considerations associated with maxillofacial trauma patient care. New to this edition are over 700 full-color illustrations showing details of traumatic injuries and their treatment. Edited by head and neck trauma expert Dr. Raymond J. Fonseca, along with over 80 highly respected contributors, this comprehensive reference provides all of the information you need to offer the best care possible to maxillofacial trauma patients. - One-of-a-kind, comprehensive chapters cover current research literature with topics including advances in maxillofacial trauma surgery, nonpenetrating chest trauma, metabolic response to trauma, maxillofacial prosthetics, and the societal impact of maxillofacial trauma. - Coverage of emerging topics includes firearm injuries, neurologic injuries (the leading cause of death from trauma), wound healing, airway management, shock, and nasal fractures, so you can work confidently with team members from other disciplines such as neurologists, anesthesiologists, and orthopedists. - Over 80 expert contributors represent the specialties of oral and maxillofacial surgery, anesthesiology, and otolaryngology. - UPDATED content reflects current thinking and the latest techniques in the management of traumatic injuries. - NEW full-color illustrations and design highlight clinical areas and show details of injuries and their treatment. - NEW! Streamlined, single-volume format makes information easier to access and the book easier to carry.

As the population of patients with acute or chronic kidney disease grows, healthcare professionals need a resource that optimizes drug effectiveness while minimizing potential toxicity. Renal Pharmacotherapy is a comprehensive listing of dosage recommendations for patients with compromised renal function. This up-to-date and evidence-based reference closes several identified knowledge gaps concerning medications eliminated by the kidneys. Conveniently listed alphabetically by generic drug name, each drug has its own face page featuring typical dosing ranges, alternative dosing adjustments by strata of renal function, specific dosing for dialysis and other dosing schemes. This work will satisfy the dosing information needs of busy physicians involved in pharmacotherapy for patients with kidney disease, as well as pharmacists, nurses and students.

If you work with children, you must have this book.For more than two decades, Pediatric Injectable Drugs (The Teddy Bear Book), has served an important and continuing need for reliable evidence-based information specific to pediatric injectable drugs.The tenth edition of this invaluable reference has grown to cover 238 drugs commonly used in the treatment of infants and children, including 20 new to this edition. The Teddy Bear Book covers neonates through adolescents, with age-specific dosing and administration guidelines throughout. With three new editors, who collectively bring 75 years of pediatric pharmacy practice experience to the book, the tenth edition is the most thorough and comprehensive reference yet.As with previous editions, the structure of each of the drug monographs covers the following areas: Brand Names Medication Error Potential Contraindications and Warnings Infusion-Related Cautions Dosage (age specific) Dosage Adjustment in Organ Dysfunction Maximum Dosage Additives Suitable Diluents Maximum Concentrations Preparation and Delivery IV Push Intermittent Infusion Continuous Infusion Other Routes of Administration

Clinical Physiology of the Venous System is a comprehensive overview of vein physiology. - Presents data in the fields of venous physiology, pharmacology and venous diseases as well as the field of phlebology, which has seen rapid and important progress in the last decade. - Recent developments in venous disorders are covered with regard to pathophysiology; most modern diagnostic methods and therapies. - Venous tone regulation data is presented with a focus on neural; hormonal; local and myogenic control of venous smooth muscle. Special attention was paid to endothelium-derived vasoactive factors involved in the regulation of venous tone. - Take home messages at the beginning of each chapter for quick review. - List of key abbreviations used in the book. - Well illustrated with teaching tables. - Useful for any physician, researcher or student interested in vein physiology.

Pruning Plant By Plant is a pruning visual guide in a handy format that covers all of the most popular plants. There is clear text and an artwork for every plant that explains the reasons for pruning and the correct timing, and shows exactly where and how to cut. Formative, remedial, and regular pruning advice tells you how to look after your plants from their first year through to maturity. Detailed artwork and clear photographs show you exactly where to cut, giving gardeners of all abilities the confidence to prune with precision.

The foundational reference in dermal toxicology, this classic text has been completely revised to bring it up to date in the new Eighth Edition, with almost a third of its chapters being newly added. The structure of the text has also been reorganized to enable easier location of a topic of interest. With contributions from leading international ex

Pediatric Anesthesia: Basic Principles—State of the Art—Future contains the contributions of 220 international experts from all five continents. This is the only textbook of its kind that has such a strong international representation of the very best authorities in the field.

Stockley's Drug Interactions, edited by Karen Baxter, remains the world's most comprehensive and authoritative reference book on drug interactions.: Contains detailed yet concise monographs; Covers interactions between therapeutic drugs, proprietary medicines, herbal medicines, foods, drinks, pesticides and drugs of abuse; Based on published sources and fully referenced; Global coverage - inclusion of drugs used worldwide; Provides comprehensive details of the clinical evidence for the interactions under discussion, an assessment of their clinical importance and gives clear guidance on how to.

Addressing the increased use of protein and peptide candidates as treatments for previously untreatable diseases, this comprehensive and progressive source provides the reader with a roadmap to an increased understanding of issues critical for successfully developing a protein or peptide therapeutic candidate. Proteins and Peptides is

Drs Eduardo D. Bruera and Russell K. Portenoy have completely revised and updated the widely respected Cancer Pain: Assessment and Management for the second edition of this unanimously praised book. This is a comprehensive, clinically oriented review of all aspects of the complex and multidimensional problem of cancer pain. The unique characteristics of cancer pain, including pathophysiology, clinical assessment, diagnosis, and pharmacological and nonpharmacological management are all discussed here in detail. Internationally recognized leaders in cancer pain research have contributed to many new chapters, including neuraxial analgesia, hospice and institution-based palliative care programs, bone pain, and cancer pain and palliative care in the developing world. Cancer Pain continues to be a scholarly but accessible text that is an essential resource for physicians, nurses, and medical students who treat suffering from cancer pain.

Now in its 7th edition, this popular, must-have text remains the only encyclopedic resource for veterinary internal medical problems. The internationally acclaimed'gold standard'offers unparalleled coverage of pathophysiology, diagnosis, and treatment of diseases affecting dogs and cats, as well as the latest information on the genome, clinical genomics, euthanasia, innocent heart murmurs, hyperbaric medicine, home prepared and raw diets, obesity, botulism, artificial pacing of the heart, cancer vaccines, and more. The 7th edition combines the convenience of a two-volume printed textbook with the enhanced functionality of an Expert Consult website that enables you to electronically search your entire book and study more efficiently. With instant access to the most reliable information available, you'll always be at the forefront of veterinary care! Fully searchable online text provides fast, easy access to the most reliable information in the field. More than 150 clinical algorithms throughout the text aid in disease-identification and decision-making. Expanded online chapter content enhances your understanding through additional text, illustrations, tables, and boxes. Hyperlinked client information sheets streamline reference of specific conditions and enhance communication with clients. Extensive online reference list directs you to full-text PubMed abstracts for additional research. Thoroughly updated and expanded content, including 90 new chapters, addresses the latest developments across the full spectrum of small animal care. Companion Expert Consult website enhances your learning experience with the ability to search the entire electronic text instantly for easy reference. Expert Consult also gives you instant access to: More than 150 procedural videos that guide you step-by-step through essential procedures. Audio files that help you identify heart abnormalities by their sound.

Previous ed.: 2007.

Treatment is the heart of medicine. For patients, the main aim of visiting a physician is to get the best therapy. Therapy has a long history. Advanced biotechnology helps improve medical treatment. Apart from the classical treatments, there are many new emerging means of medical treatment. In this book, the concept of new therapeutic channels, cell, gene and molecular concepts is developed. Interesting details on concepts for these modern therapies can be found in this book and this book.

This collection focuses on recent advances in laboratory and field testing of unsaturated soils. Leading researchers from fourteen countries to represent global research in the area of experimental unsaturated soil mechanics have been invited to contribute to this book. Twelve reports are presented dealing with measurement and control of suction and water content, mechanical, hydraulic, and geo-environmental testing, microstructure investigation, and applications of unsaturated soil monitoring to engineering behaviour of geo-structures. The main motivation behind this book is the rapid growth of experimental unsaturated soil mechanics over the last couple of decades. Several innovative laboratory and field techniques have been introduced in mechanical, hydraulic, and geo-environmental testing. However, this information is widely dispersed in journals and conference proceedings and researchers and engineers beginning to work in the field of unsaturated soil mechanics may find it difficult to identify suitable equipment and instrumentation for research or professional purposes. Audience: This volume aims at providing scientists and practitioners with a comprehensive overview of experimental unsaturated soil mechanics.

Photosynthesis is a metabolic pathway that converts light energy into chemical energy. Its initial substrates are carbon dioxide and water; the energy source is sunlight (electromagnetic radiation); and the end-products are oxygen and (energy-containing) carbohydrates, such as sucrose, glucose or starch. This process is one of the most important biochemical pathways, since nearly all life on Earth either directly or indirectly depends on it as a source of energy. It is a complex process occurring in plants, algae, as well as bacteria such as cyanobacteria. This new book presents the latest research in the field with special emphasis on energy, biotechnology and nanotechnology.

Opioids have become invaluable in modern medicine but it is essential that they are prescribed with an understanding of the complex pharmacology behind their effectiveness; without this, they will frequently fail to achieve their enormous potential of pain relief, minimal side effects, and improved function. In addition, opioids come with problems, including side effects such as constipation, respiratory depression, and sedation, as well as the potential for substance abuse. Clinicians handling the complex pain problems of cancer patients must incorporate the insight of basic scientists and pharmacologists, and this new edition of this comprehensive text brings together a wealth of experience from those involved in all aspects of opioids, with a view to improving both clinician understanding and patient care. The text includes comprehensive coverage of the principles of opioid pharmacodynamics, pharmacokinetics, and pharmacogenetics. A chapter is dedicated to each of the main opioids, with topics such as structure, routes of administration, toxicity, drug interactions, and effects on organ function included within each one. The book concludes with several chapters dedicated to discussion of the major issues relevant to opioid use, including substance abuse, dosing strategies for acute and chronic pain, patient controlled analgesia, equianalgesia, spinal opioids, pain that doesn't respond to opioids, and the terminal phase. This text is the most complete and extensive work available on the use of opioids for cancer pain, and is an important reference for those clinicians treating individuals with cancer.

Nowhere in medicine is there a greater imperative to act than in the recognition and management of a patient's pain. This practical and evidence-based resource for emergency medicine and acute care providers will guide physicians in the selection of an effective therapy, define appropriate dosages to use and, equally important, when a treatment doesn't work, explain why, and what to do next. Starting with chapters on the assessment of pain, the safe and effective provision of analgesia in special populations, and featuring a reference table of drug names and interactions; the bulk of the coverage moves on to describe the provision of analgesia in the wide range of conditions likely to be encountered in the emergency department. The fundamental strengths of this approach are the comprehensive coverage, focus on practicality, basis in sound evidence, and authorship by specialists with extensive experience based on years of clinical practice.

Sepsis is an important public health problem around the world. Severe sepsis carries significant morbidity, mortality and high costs. The incidence of sepsis is increasing because of the aging population, the growing number of immunocompromised hosts, the increasing use of invasive procedures, and, to a lesser extent, antibiotic resistance among pathogens. Despite recent advances in the pathogenesis, diagnosis, and therapeutic approaches the mortality rate associated with this condition remains high. Therefore, the goal of Sepsis: New Strategies is to review novel targets to be considered in patients with severe sepsis and to assess new developments for patients with sepsis originating in the respiratory tract.

Textbook of Palliative Medicine provides an alternative, truly international approach to this rapidly growing specialty. This textbook fills a niche with its evidence-based, multi-professional approach and global perspective ensured by the international team of editors and contributing authors. In the absence of an international curriculum for the study of palliative medicine, this textbook provides essential guidance for those both embarking upon a career in palliative medicine or already established in the field, and the structure and content have been constructed very much with this in mind. With an emphasis on providing a service anywhere in the world, including the important issue of palliative care in the developing nations, Textbook of Palliative Medicine offers a genuine alternative to the narrative approach of its competitors, and is an ideal complement to them. It is essential reading for all palliative care physicians in training and in practice, as well as palliative care nurses and other health professionals in the palliative care team

Many recent discoveries in both laboratory and clinical settings have greatly increased our understanding of sleep medicine and the relevant psychopharmacology. This timely book serves to present updated information about the neuropsychopharmacology of sleep as this field enters mainstream psychiatry, neurology and medicine This volume has assembled articles that summarize and review carefully, a chosen selection of the latest discoveries concerning sleep medicine, sleep physiology and sleep pharmacology. Outstanding contributions have been sought from acknowledged experts in their respective fields. The goal of the volume is to present the more recent developments and advances in the fields of sleep and neuropsychopharmacology, as well as to provide a context for considering them both in depth and from multidisciplinary perspectives. This volume brings together the collective expertise of clinicians and basic researchers who represent a range of interests in neuroscience, neuropharmacology, sleep physiology, and biological rhythms. Presenting a thoughtful balance of basic experimental and clinical facts and viewpoints, this book will serve as a foundation for understanding, and ultimately treating, sleep disorders.

- Not only written by experts but the content of each of the chapters has also been peer-reviewed. - Presents a step-by-step approach to the treatment of chronic wounds. - For dermatologists, but also many other medical disciplines such as general practitioners and family physicians who also treat chronic wounds.

An in-depth review by leading authorities of the latest therapies and techniques for rescuing persons in cardiac arrest. The authors explore the physiology behind current state-of-the-art clinical resuscitation and translate it into practical bedside recommendations, clinical tips, and expert techniques. Topics of interest include the epidemiology of sudden death, management of ventilation, chest compression technique training, public access defibrillation, drug delivery during CPR, the latest drug therapies, and cardiac arrest in disease, pregnancy, drowning, lightning strike, and trauma. The authors also review the major ongoing research in resuscitation science that will likely affect the next set of international resuscitation guidelines.

Title from ebook title screen (viewed April 7, 2005).

This thoroughly revised second edition addresses the full spectrum of cereal grain science, employing agronomic, chemical, and technological perspectives and providing new and expanded treatment of food enrichment techniques, nutritional standards, and product quality evaluation. Written by over 40 internationally respected authorities, the