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High-Performance Materials from Bio-based Feedstocks The latest advancements in the production, properties, and performance of bio-based feedstock materials In High-Performance Materials from Bio-based Feedstocks, an accomplished team of researchers delivers a comprehensive exploration of recent developments in the research, manufacture, and application of advanced materials from bio-based feedstocks. With coverage of bio-based polymers, the inorganic components of biomass, and the conversion of biomass to advanced materials, the book illustrates the research and commercial potential of new technologies in the area. Real-life applications in areas as diverse as medicine, construction, synthesis, energy storage, agriculture, packaging, and food are discussed in the context of the structural properties of the materials used. The authors offer deep insights into materials production, properties, and performance. Perfect for chemists, environmental scientists, engineers, and materials scientists, High-Performance Materials from Bio-based Feedstocks will also earn a place in the libraries of academics, industrial researchers, and graduate students with an interest in biomass conversion, green chemistry, and sustainability. A thorough introduction to the latest developments in advanced bio-based feedstock materials research Comprehensive explorations of a vast range of real-world applications, from tissue scaffolds and drug delivery to batteries, sorbents, and controlled release fertilizers Practical discussions of the organic and inorganic components of biomass and the conversion of biomass to advanced materials In-depth examinations of the structural properties of commercially and academically significant biomass materials For more information on the Wiley Series in Renewable Resources, visit www.wiley.com/go/rrs

Evidence-Based Sexual and Reproductive Health Care: Policies, Clinical Procedures, and Related Research embraces the concept of a multi-professional approach to clinical care excellence in sexual and reproductive health care. A comprehensive resource, it explores the complex nature of sexual health related issues, contemporary management interventions, and the underpinning theories and concepts. With contributions from leading experts from around the globe, the text features perspectives from a wide variety of fields, such as education, medicine, nursing, and the health professions. User-friendly and practical in approach, it explores current and future developments, ongoing research, new treatment procedures, and emerging technological advancements. Important Notice: The digital edition of this book is missing some of the images or content found in the physical edition.

Nanotechnology seeks to exploit distinct technological advances controlling the structure of nanoscale biomaterials at a nanodimensional scale approaching individual molecules and their aggregates or supramolecular structures. The term'nanomedicine'is used to describe those technologies under the umbrella of nanotechnology that have therapeutic applications in human health. This book presents recent trends and research achievements in the field of pharmaceutical nanotechnology and advanced drug delivery nanosystems, especially for theranostic purposes. The applications of drug delivery nanosystems considered carriers of active pharmaceutical ingredients (APIs) (e.g., proteins, peptides, and nucleic acids) are analyzed on the basis of technology, preparation protocols, and biomedical applications. The book also extensively reports on the principles, design protocols, and applications of nanosystems in drug delivery, imaging, and targeting of active molecules of pharmaceutical interest.

This book addresses a range of synthesis and characterization techniques that are critical for tailoring and broadening the various aspects of polymer gels, as well as the numerous advantages that polymer gel-based materials offer. It presents a comprehensive collection of chapters on the recent advances and developments in the science and fundamentals of both synthetic and natural polymer-based gels. Topics covered include: synthesis and structure of physically/chemically cross-linked polymer-gels/polymeric nanogels; gel formation through non-covalent cross-linking; molecular design and characterization; polysaccharide-based polymer gels: synthesis, characterization, and properties; modified polysaccharide gels: silica-based polymeric gels as platforms for the delivery of pharmaceuticals; gel-based approaches in genomic and proteomic sciences; emulgels in drug delivery; and organogels. The book provides a cutting-edge resource for researchers and scientists working in various fields involving polymers, biomaterials, bio-nanotechnology and functional materials.

The aim of this book is to better understand the phenomenon of HIV in a country that has faced the fullest might of the disease and yet, after first faltering, has made more progress than any other country in the world in its response to HIV. It aims to reflect the complexity of this narrative and the range of widely differing insights by featuring what is likely the largest number of contributors in a single publication on the subject in South Africa, as well as a full spectrum of specialised areas, ranging from high-end science to personal reflections.

One of the most promising new approaches for the prevention of HIV transmission, particularly for developing countries, involves topical, self-administered products known as microbicides. The development of microbicides is a long and complicated process, and this volume provides an overview of all the critical areas, from the selection of appropriate candidate molecules and their formulation, preclinical and clinical testing for safety and efficacy, strategies for product registration and finally, issues associated with product launch, distribution and access. The book will prove valuable to both those working in the field and all others who are interested in learning more about this product class, which has the potential to significantly impact the future of this devastating epidemic.

The concept of focal controlled drug delivery has been applied for treating illnesses that are localized to a certain tissue or organ. These delivery systems are applied directly to the diseased site and deliver a desired dose for an extended time period while minimizing systemic distribution of toxic drug. Controlled drug delivery systems have been focused on oral extended release formulations and on systemic delivery of small drugs and peptides. Despite the upsurge of interest in focal targeted drug delivery, there is currently no single reference text on the subject. By comparison, there are numerous authored and edited books on oral, systemic and transdermal drug delivery or books on biodegradable polymers as drug carriers. Thus, the aim of Focal Drug Delivery is to bring together leading experts and researchers in the field to provide an authoritative account of the essential pharmaceutical, technological, physiological and biological sciences underpinning the topic. In addition, the book will review advances in treatment options for diseases localized at a certain tissue or organ.

The worldwide impact of HIV/AIDS is well recognized. This book provides for the first time a thorough and critical overview of current aspects, recent developments, and trends in the formulation and drug delivery concerning anti-HIV microbicides by leading scientists in the field. Additionally, pertinent regulatory aspects and socioeconomical issue

In Memoriam of Alfred S. Evans This third edition of Bacterial Infections of Humans is dedicated to Alfred Spring Evans, who died on January 21, 1996, 2Yz years after a diagnosis of cancer. Al was the senior editor of this textbook, which he founded with Harry Feldman in 1982. Al was a clinician, epidemiologist, educator, catalyst for biomedical research, historian, author, speaker, seeker of the truth, sincere friend of students, sports enthusiast, traveler, and truly a man of all seasons. He was a devoted husband to Brigette Klug Evans, father of three children, and grandfather of four. Al was born in Buffalo, New York, on August 21,1917, to Ellen Spring and John H. Evans, M.D., one ofthe United States's first anesthesiologists and an early researcher in the field of oxygen therapy. He received his undergraduate training at the University of Michigan; was awarded an M.D. degree in 1943 from the University of Buffalo; interned in Pittsburgh, Pennsylvania; and performed his medical residency at the Goldwater Hospital in New York City. He was in the United States Army from 1944 to 1946, assigned as a public health officer to a base in Okinawa, Japan. It was there that he met Drs.

The last decade has seen a huge amount of change in the area of sexually transmitted infection control and prevention, including the development of high-profile vaccines for preventing the spread of cervical cancer-causing human papillomavirus (HPV), novel control methods for HIV and AIDS, and even the discussion of more widespread use of controversial abstinence-only sex education programs. Fully revised and updated to reflect the changes of the past ten years, Sexually Transmitted Diseases: Vaccines, Control and Prevention, Second Edition brings researchers, clinical investigators, clinicians, and students the most up-to-date research, findings and thought on sexual infection prevention, control and therapy available and serves as an essential reference for anyone working in the field. - Provides comprehensive coverage of epidemiology, physiology and immunology, featuring general preventive strategies such as behavioural modification, barrier methods and topical microbicides - Presents individual chapters on Herpes Simplex Virus, Papillomavirus, Hepatitis B, Chlamydia, Gonorrhea, Syphilis, and Bacterial Vaginosis - Includes pathogenesis, microbiology and clinical manifestations of each STD, along with current advances in vaccine development

By focusing on general molecular mechanisms of antiviral drugs rather than therapies for individual viruses, this ready reference provides the critical knowledge needed to develop entirely novel therapeutics and to target new viruses. It begins with a general discussion of antiviral strategies, followed by a broad survey of known viral targets, such as reverse transcriptases, proteases, neuraminidases, RNA polymerases, helicases and primases, as well as their known inhibitors. The final section contains several cases studies of recent successful antiviral drug development. Edited by Erik de Clercq, the world authority on small molecule antiviral drugs, who has developed more new antivirals than anyone else.

HIV/AIDS continues to be the pandemic of our times and there has not been a comprehensive medically based AIDS prevention book published in the last 5 years. It is estimated that 36 to 45 million people including 2-3 million children already are infected worldwide and an additional 4-7 million more are infected each year. There are about 6,000 new infections daily and about 12 million AIDS orphans. People receiving AIDS treatments feel well and have no detectable viral load, but still can infect others. And even when a vaccine is found, it will take many years before it can be administered across the developing world. - Discusses all aspects of AIDS prevention, from epidemiology, molecular immunology and virology to the principles of broad-based public health prevention interventions - Special focus on the array of interventions that have been proven effective through rigorous study - Identifies new trends in HIV/AID epidemiology and their impact on creating and implementing prevention interventions - Incorporates virology, biology, infectious diseases, vaccinology, microbicides and research methodologies into AIDS prevention

In Memoriam of Alfred S. Evans The third edition of Bacterial Infections of Humans is dedicated to Alfred Spring Evans, who died on January 21, 1996, 2 ½ years after a diagnosis of cancer. Al was the senior editor of this textbook, which he founded with Harry Feldman in 1982. Al was a clinician, epidemiologist, educator, ca- lyst for biomedical research, historian, author, speaker, seeker of the truth, sincere friend of students, sports enthusiast, traveler, and truly a man of all seasons. He was a devoted husband to Brigette Klug Evans, father of three children, and grandfather of four. Al was born in Buffalo, New York, on August 21, 1917, to Ellen Spring and John H. Evans, M. D., one of the United States's?rst anesthesiologists and an early researcher in the?eld of oxygen therapy. He received his undergraduate training at the University of Michigan; was awarded an M. D. degree in 1943 from the University of Buffalo; interned in Pittsburgh, Pe- sylvania; and performed his medical residency at the Goldwater Hospital in New York City. He was in the United States Army from 1944 to 1946, assigned as a public health of?cer to a base in Okinawa, Japan. It was there that he met Drs. Albert Sabin and John R. Paul, who came to Okinawa to test a new Japanese encepha- tis vaccine. Al was invited by Dr. Paul to come to Yale Alfred S.

HIV/AIDS management poses many different challenges around the world, and the therapies available in the West are often not economically feasible in developing countries. This new book is the first to address the myriad of clinical difficulties faced by health practitioners worldwide in managing HIV/AIDS. Edited by the same authorities responsible for the highly respected reference'The Medical Management of AIDS,'with Associate Editors that include the President of the International AIDS Society and a preeminent opinion leader in the fight against AIDS in Africa, and authored by a'who's who'of current global experts on HIV and AIDS medicine, this visionary text presents all the practical, indispensable information that clinicians everywhere need to offer their patients the best possible care.Access reliable, up-to-the-minute guidance that addresses the realities of HIV/AIDS management in your geographical region, thanks to contributions from a global cast of renowned expert clinicians and researchers.Locate the clinically actionable information you need quickly with an organization that mirrors the current state of the AIDS epidemic and the different needs of Western vs. developing-world patients and clinicians.Diagnose AIDS manifestations confidently by comparing them to full-color clinical images.Review essential data quickly through numerous at-a-glance tables.

Some books break myths. Others break silences. A few break new ground. The Health of Sexual Minorities achieves all three aims. The first book of its kind, this resource offers a multidimensional picture of lesbian, gay, bisexual and transgender (LGBT) health across clinical and social disciplines to give readers a full and nuanced understanding of these diverse populations. Here are real-world matters of definition and self-definition (including sexual identity, gender identity, and anti-identity), meticulous analyses of stressor and health outcomes, a extensive coverage of research methodology concerns, and critical insights into the sociopolitical context of LGBT individuals'health and lives. - Developmental issues across the lifecourse - Human rights and ethical issues - Global perspectives of LGBT health - Physical and mental health issues - Issues and concerns of racial/ethnic minority groups - Health concerns of lesbian and bisexual women - Prejudice and homophobia as social stressors - A comprehensive review of quantitative and qualitative research methodology - Tobacco, alcohol, and substance use issues - The current state of LGBT health care and strategies for improvement - The impact of the HIV/AIDS epidemic on LGBT communities The Health of Sexual Minorities is an advanced-level text whose scope and accessibility makes it useful to a broad audience. Over 50 contributors have made this a work of crucial importance to public health and health care professionals and biomedical and social science researchers. The Health of Sexual Minorities encourages clear thinking, informed practice, and effective, progressive policy for improved health and well-being of LGBT individuals and communities.'The Health of Sexual Minorities is a welcome and much needed comprehensive text focused on lesbian, gay, bisexual, and transgender(LGBT) populations, chiefly in the U.S. but also globally. Of use to researchers, practitioners, and advocates alike, the text covers key conceptual, methodological, and substantive issues. Its critical analysis of how unjust sexual hierarchies harm health exemplifies why LBGT health and health care issues must be analyzed and addressed in context: in relation to gender, class, racism, and the ways in which sociopolitical conditions shape LGBT identity and health.'--Nancy Krieger, Ph.D. Professor, Department of Society, Human Development and Health, Harvard School of Public Health

The AIDS Pandemic explores the ways in which HIV/AIDS has, and continues to transform the wide range of related disciplines it touches. Novel perspectives are provided by a unique panel of internationally recognised experts who cover the unprecedented impact onf AIDS on culture, demographics and politics around the world, including how it affected the worlds'economy, health sciences, epidemiology and public health. This important far- reaching analysis uses the lessons learned from a wide array of disciplines to help us understand the current status and evolution of the pandemic, as it continues to evolve.• Unique and timely presentation of new theories and perspectives• Concentrates on the changes that have taken place in a broad array of related disciplines• Provides key contextual information, for those new to the field or at interface areas between disciplines• Includes an international focus on evolving African and Asian experiences• Focuses on the current strategies for developing vaccines and microbicides• Outlines harm reduction and prevention programs• Explores issues related to delivery of life-saving AIDS medications in resource-constrained environments