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This book will examine the relevant biological subjects involved in biomimetic microengineering as well as the design and implementation methods of such engineered microdevices. Physiological topics covered include regeneration of complex responses of our body on a cellular, tissue, organ, and inter-organ level. Technological concepts in cell and tissue engineering, stem cell biology, microbiology, biomechanics, materials science, micro- and nanotechnology, and synthetic biology are highlighted to increase understanding of the transdisciplinary methods used to create the more complex, robust biomimetic engineered models. The effectiveness of the new bioinspired microphysiological systems as replacements for existing in vitro or in vivo models is explained through sections that include the protocols to reconstitute three-dimensional (3D) structures, recapitulate physiological functions, and emulate the pathophysiology of human diseases. This book will also discuss how researchers can discover bridge technologies for disease modeling and personalized precision medicine.Features Focuses on cutting edge technologies that enable manipulation of living systems in a spatiotemporal manner. Incorporates research on reverse engineering of comples microenvironmental factors in human diseases. Highlights technologies related to patient-specific personalized medicine and their potential uses. Written by chapter authors who are highly respected researchers in science and engineering. Includes extensive references at the end of each chapter to enhance further study. Hyun Jung Kim is an Assistant Professor in the Department of Biomedical Engineering at The University of Texas at Austin. After receiving hois Ph.D. degree at Yonsei University in the Republic of Korea, he did extensive postdctoral research at both the University of Chicago and the Wyss Institute at Harvard University. These efforts resulted in cutting-edge breakthroughs in synthetic microbial community research and organomimetic human Gut-on-a-Chip microsystem. His research on Gut-on-a-Chip technology leads to the creation of a microfluidic device that mimics the physiology and pathology of the living human intestine. Since 2015, he has explored novel human host-microbiome ecosystems to discover the disease mechanism and new therapeutics in inflammatory bowel disease and colorectal cancers at UT Austin. In collaboration with clinicians, his lab is currently developing disease-oriented, patient-specific models for the advancement in pharmaceutical and clinical fields.

Pulitzer Prize FinalistSilver Gavel Award Finalist“A sobering history of how American communities and institutions have relied on torture in various forms since before the United States was founded.”—Los Angeles Times“That Americans as a people and a nation-state are violent is indisputable. That we are also torturers, domestically and internationally, is not so well established. The myth that we are not torturers will persist, but Civilizing Torture will remain a powerful antidote in confronting it.”—Lawrence Wilkerson, former Chief of Staff to Secretary of State Colin Powell“Remarkable…A searing analysis of America's past that helps make sense of its bewildering present.”—David Garland, author of Peculiar InstitutionMost Americans believe that a civilized state does not torture, but that belief has repeatedly been challenged in moments of crisis at home and abroad. From the Indian wars to Vietnam, from police interrogation to the War on Terror, US institutions have proven far more amenable to torture than the nation's commitment to liberty would suggest.Civilizing Torture traces the history of debates about the efficacy of torture and reveals a recurring struggle to decide what limits to impose on the power of the state. At a time of escalating rhetoric aimed at cleansing the nation of the undeserving and an erosion of limits on military power, the debate over torture remains critical and unresolved.

Contributions by W. Fitzhugh Brundage, Jordan Burke, Rebecca Bennett Clark, James C. Cobb, Anna Creadick, Colin Dayan, Wai Chee Dimock, Sarah E. Gardner, Hannah Godwin, Brooks E. Hefner, Andrew B. Leiter, Sean McCann, Conor Picken, Natalie J. Ring, Calvin Schermerhorn, and Jay Watson William Faulkner remains a historian's writer. A distinguished roster of historians are drawn to him as a fellow historian, a shaper of narrative reflections on the meaning of the past; as a historiographer, a theorist and dramatist of the fraught enterprise of doing history; and as a historical figure himself, especially following his mid-century emergence as a public intellectual after winning the Nobel Prize for Literature. This volume brings together historians and literary scholars to explore the many facets of Faulkner's relationship to history: the historical contexts of his novels and stories; his explorations of the historiographic imagination; his engagement with historical figures from both the regional and national past; his influence on professional historians; his pursuit of alternate modes of temporal awareness; and the histories of print culture that shaped the production, reception, and criticism of Faulkner's work. Contributors draw on the history of development in the Mississippi Valley, the construction of Confederate memory, the history and curriculum of Harvard University, twentieth-century debates over police brutality and temperance reform, the history of modern childhood, and the literary histories of antislavery writing and pulp fiction to illuminate Faulkner's work. Others in the collection explore the meaning of Faulkner's fiction for such professional historians as C. Vann Woodward and Albert Bushnell Hart. In these ways and more, Faulkner and History offers fresh insights into one of the most persistent and long-recognized elements of the Mississippian's artistic vision.

The 1641 rebellion is one of the seminal events in early modern Irish and British history. Its divisive legacy, based primarily on the sharply contested allegation that the rebellion began with a general massacre of Protestant settlers, is still evident in Ireland today. Indeed, the 1641 ‘massacres', like the battles at the Boyne (1690) and Somme (1916), played a key role in creating and sustaining a collective Protestant/ British identity in Ulster, in much the same way that the subsequent Cromwellian conquest in the 1650s helped forge a new Irish Catholic national identity. Following a successful hardback edition, Ó Siochrú and OIhlmeyer's popular title is now available in paperback. The original and wide-ranging themes chosen by leading international scholars for this volume will ensure that this edited collection becomes required reading for all those interested in the history of early modern Europe. It will also appeal to those engaged in early colonial studies in the Atlantic world and beyond, as the volume adopts a genuinely comparative approach throughout, examining developments in a broad global context.

“I want Paula or her body—I don't care which.”This was the command of her wealthy, ruthless father. But Abel Cain, who undertook the search, found that he had been presented with only one side of the ugly truth. There were others looking for the hidden heiress too, and among them were the forces of jealousy, greed, and murderous vengeance.When and island orgy held by Paula's friends backfired and the two-faced revelers uncovered a surprise coffin, Cain found the key to his puzzle, one that pointed to something terribly simple and utterly evil.This new novel, an ACE Original, presents some saucy humor, stalking females, and a bevy of up-to-no-good sophisticates thrown against background of fast action and awesome terror. It will keep you guessing and breathless all the way.

Here's help in selecting current, nonfiction books that will get boys excited about reading.Enticing boys to read is still a hot topic. With chapters like'Disasters and Mysteries,''Gross and Disgusting,''Machines and the Military,'and'Prehistoric Creatures,'Gotcha Again for Guys!: More Nonfiction Books to Get Boys Excited about Reading is a treasure trove of recent nonfiction books that will interest boys in grades 3-8.This sixth entry in Baxter and Kochel's Gotcha series covers books published between 2007 and 2009, with a few oldies-but-goodies also included. The book is organized into 12 thematic chapters, each of which offers booktalks for a select number of titles, followed by a list of other high-interest, well-reviewed titles that correspond with the chapter's topic. Features new to this volume include numerous booklists to be copied and saved, as well as profiles of new and innovative nonfiction authors writing for this age group. In addition, the book features interviews with seven male authors of nonfiction books for boys.

Obscene, libidinous, loathsome, lascivious. Those were just some of the ways critics described the nineteenth-century weeklies that covered and publicized New York City's extensive sexual underworld. Publications like the Flash and the Whip—distinguished by a captivating brew of lowbrow humor and titillating gossip about prostitutes, theater denizens, and sporting events—were not the sort generally bound in leather for future reference, and despite their popularity with an enthusiastic readership, they quickly receded into almost complete obscurity. Recently, though, two sizable collections of these papers have resurfaced, and in The Flash Press three renowned scholars provide a landmark study of their significance as well as a wide selection of their ribald articles and illustrations. Including short tales of urban life, editorials on prostitution, and moralizing rants against homosexuality, these selections epitomize a distinct form of urban journalism. Here, in addition to providing a thorough overview of this colorful reportage, its editors, and its audience, the authors examine nineteenth-century ideas of sexuality and freedom that mixed Tom Paine's republicanism with elements of the Marquis de Sade's sexual ideology. They also trace the evolution of censorship and obscenity law, showing how a string of legal battles ultimately led to the demise of the flash papers: editors were hauled into court, sentenced to jail for criminal obscenity and libel, and eventually pushed out of business. But not before they forever changed the debate over public sexuality and freedom of expression in America's most important city.

African-American writer Richard Wright (1908-1960) was celebrated during the early 1940s for his searing autobiography (Black Boy) and fiction (Native Son). By 1947 he felt so unwelcome in his homeland that he exiled himself and his family in Paris. But his writings changed American culture forever, and today they are mainstays of literature and composition classes. He and his works are also the subjects of numerous critical essays and commentaries by contemporary writers. This volume presents a comprehensive annotated bibliography of those essays, books, and articles from 1983 through 2003. Arranged alphabetically by author within years are some 8,320 entries ranging from unpublished dissertations to book-length studies of African American literature and literary criticism. Also included as an appendix are addenda to the author's earlier bibliography covering the years from 1934 through 1982. This is the exhaustive reference for serious students of Richard Wright and his critics.

“I want Paula or her body—I don't care which.” This was the command of her wealthy, ruthless father. But Abel Cain, who undertook the search, found that he had been presented with only one side of the ugly truth. There were others looking for the hidden heiress too, and among them were the forces of jealousy, greed, and murderous vengeance. When and island orgy held by Paula's friends backfired and the two-faced revelers uncovered a surprise coffin, Cain found the key to his puzzle, one that pointed to something terribly simple and utterly evil. This new novel, an ACE Original, presents some saucy humor, stalking females, and a bevy of up-to-no-good sophisticates thrown against background of fast action and awesome terror. It will keep you guessing and breathless all the way.