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Encyclopedia of Respiratory Medicine, Second Edition, Six Volume Set explores the key processes of lung diseases and their diagnosis and management. The book dissects the molecular and cellular biology, physiology and immunology that underpin normal lung function, along with the aberrations that occur in respiratory diseases, from common disorders such as asthma and COPD to rarer lung diseases such as cystic fibrosis, interstitial lung diseases and pulmonary hypertension. Written in at a time when the globe is in the grip of respiratory pandemic, lung disease has never been so prominent in the public and political conscious. This new edition will provide new researchers in respiratory medicine with a solid foundation in unfamiliar topics and will update more experienced researchers seeking to step outside their core areas of research to put their work into a broader context. - Presents a'one-stop'resource covering the entire scope of modern respiratory medicine - Brings together a truly global collaboration of some of the most authoritative voices in respiratory medicine - Provides chapters that are concise and accessible, with an authoritative introduction for non-specialists, as well as up-to-date, foundational content for those familiar with the field - Includes multimedia-rich content, including hundreds of clear and helpful illustrations that can be used as teaching aids

Paratuberculosis, also referred to as Johne's disease, affects principally cattle, goats, sheep, buffalo, deer and other ruminants. It is common worldwide and responsible for significant economic losses in the ruminant livestock industries. A timely follow up to the first book on Paratuberculosis, this new edition is still the only comprehensive text providing both historical context and the latest developments in the field. Examining the epidemiology of paratuberculosis, the organism that causes the disease, and practical aspects of its diagnosis and control, it also addresses the link between paratuberculosis in the food chain and human health implications, including Crohn's disease. This new edition: · Builds on a strong foundation to update, streamline and better structure existing chapters with important new developments from the last decade, such as whole genome sequencing and phage-based assays; · Includes new chapters on the fast-growing field of whole genome based comparative genomics, and the increasing opportunities for disease control in low- and middle-income countries; · Increases inclusivity by bringing on board new rising star authors from diverse backgrounds to provide international perspectives. A truly comprehensive, critical reference resource, this book is an essential reference for large animal veterinarians, livestock industry personnel and those involved in the dairy and meat industries, as well as microbiologists, researchers and students in these fields.

Food is an essential means for humans and other animals to acquire the necessary elements needed for survival. However, it is also a transport vehicle for foodborne pathogens, which can pose great threats to human health. Use of antibiotics has been enhanced in the human health system; however, selective pressure among bacteria allows the development for antibiotic resistance. Foodborne Pathogens and Antibiotic Resistance bridges technological gaps, focusing on critical aspects of foodborne pathogen detection and mechanisms regulating antibiotic resistance that are relevant to human health and foodborne illnesses This groundbreaking guide:• Introduces the microbial presence on variety of food items for human and animal consumption.• Provides the detection strategies to screen and identify the variety of food pathogens in addition to reviews the literature. • Provides microbial molecular mechanism of food spoilage along with molecular mechanism of microorganisms acquiring antibiotic resistance in food.• Discusses systems biology of food borne pathogens in terms of detection and food spoilage.• Discusses FDA's regulations and Hazard Analysis and Critical Control Point (HACCP) towards challenges and possibilities of developing global food safety. Foodborne Pathogens and Antibiotic Resistance is an immensely useful resource for graduate students and researchers in the food science, food microbiology, microbiology, and industrial biotechnology.

Now in its Fourth Edition, An Introduction to Medical Statistics continues to be a'must-have'textbook for anyone who needs a clear logical guide to the subject. Written in an easy-to-understand style and packed with real life examples, the text clearly explains the statistical principles used in the medical literature. Taking readers through the common statistical methods seen in published research and guidelines, the text focuses on how to interpret and analyse statistics for clinical practice. Using extracts from real studies, the author illustrates how data can be employed correctly and incorrectly in medical research helping readers to evaluate the statistics they encounter and appropriately implement findings in clinical practice. End of chapter exercises, case studies and multiple choice questions help readers to apply their learning and develop their own interpretative skills. This thoroughly revised edition includes new chapters on meta-analysis, missing data, and survival analysis.

Researchers and students of medical microbiology, infectious diseases and global health.

This new edition of Woodrow's Intensive Care Nursing will be warmly welcomed. Especially written for qualified nurses working in intensive care nursing units, this comprehensive text has been developed to be as accessible as possible. Including new chapters on planning for pandemics and transferring patients, it has been revised throughout to ensure the evidence-base is completely up-to-date and the content reflects contemporary best practice. Intensive Care Nursing is structured in user-friendly sections. Each chapter contains'fundamental knowledge'needed to understand the chapter, an introduction,'implications for practice', a chapter summary, completely updated further reading,'time out'sections for revision and a clinical scenario with questions included. Reviewed throughout by experienced practitioners and teachers, it covers: patient-focused issues of bedside nursing the technical knowledge necessary to care safely for ICU patients the more common and specialized disease processes and treatments encountered how nurses can use their knowledge and skills to develop their own and others'practice. Written by a practice development nurse with a strong clinical background in intensive care nursing and experience of teaching nursing, Intensive Care Nursing is essential reading for nurses and health professionals working with high dependency patients, particularly those undertaking further training in the area.

The first book was on'Theory and Practice'of antibiotic stewardship in its broadest sense -the how to do it and the do's and don'ts. The second, on'Controlling resistance'was very much on the relationships between use and resistance and beginning to home in on the hospital as the main generator of resistance, but mainly looking at it from a disease/clinical perspective. The last 3 chapters on MRSA, ended where the 3rd book will take off.'Controlling HAI'will concentrate on specific MDR organisms highlighting their roles in the current pandemic of HAI and emphasizing that the big issue is not so much infection control but antibiotic control, in the same way that antibiotic over-reliance/ over-use has caused the problem in the first place. Up'till now the emphasis for controlling MRSA, C diff and all the other MDROs has very much been on IC, which clearly isn't working. This book will gather all the evidence for the increasingly popular view that much more must be done in the area of antibiotic policies/ stewardship, especially when we are in danger of a'post antibiotic'era, due to a real shortage of new agents in the pipeline.

Recent advances in detection, vaccination and microbial genetics make this a timely book that examines the epidemiology of paratuberculosis, the organism that causes the disease, and practical aspects of its diagnosis and control.