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Calipered kinematic alignment was proposed by Dr. Stephen M. Howell to enable the accurate and individualized placement of total knee components coincident within ± 0.5 mm of the patient's pre-arthritic alignment. The aim was to restore the patient's native joint kinematics and thereby address the well documented 20% dissatisfaction when total knee replacement is performed using traditional, or mechanical alignment techniques. With Dr. Stefano A. Bini and Dr. G. Daxton Steele as co-editors, Dr. Howell has curated an international team of expert surgeons and engineers to discuss various aspects of the calipered knee alignment technique in short, concise, and well-illustrated chapters. Each author provides clear, practical guidance　for adopting and implementing calipered kinematic alignment covering manual, patient-specific, navigated, and robotic techniques.　Chapters on component design tailored explicitly for kinematic alignment and showing the close relationship between knee biomechanics and the kinematically aligned TKA help the surgeon manage complex challenges associated with deformity and post-operative complications. Following the introduction of the calipered kinematic alignment technique for total knee arthroplasty, many international studies have shown consistently better patient satisfaction than the traditional mechanical alignment technique. Better function and high long-term implant survival have catalyzed a paradigm shift in total knee replacement philosophy that is being embraced by orthopedic surgeons and innovative implant companies around the world with excellent results. Calipered Kinematically Aligned Knee Arthroplasty is the definitive textbook on the subject and features: - Thorough explanations of how the calipered kinematic alignment technique for total knee arthroplasty accurately sets total knee components coincident with　the patient's pre-arthritic alignment and coaligned with the three rotational axes of the native knee. - A personalized approach to total knee surgery designed to reconstitute the patient's native biomechanics in contrast　with mechanical alignment that place all patients in the same standard alignment regardless of their constitutional anatomy. - Detailed and　well-illustrated descriptions　of manual, navigated, robotic and patient-specific guide techniques that confirm kinematic alignment with a caliper. - Clinical photos, radiographs, and line art throughout the book as well as helpful online technique videos. - Key focus topics　such as managing complex deformities, the expected post-operative recovery, and future trends in kinematic alignment. - The shared experience and knowledge of international pioneers in the field. - An emphasis on a personalized surgical philosophy which enables same-day discharge, reduces pain and opioid use, and promotes quicker recovery, better function, and a more natural feeling knee.

Total knee arthroplasty (TKA) is commonly considered to be a reliable procedure, with high implant survival rates at 10 to 15 years of follow-up. The goal of total knee replacement surgery is to relieve pain and obtain better knee function. This is achieved by ensuring correct patient selection, pre-operative deformity, implant design and accurate surgical techniques. This book covers a range of techniques for the realisation of functional joint motion and stability. The first part of the book will describe fundamentals in total knee arthroplasty and alternative procedures. The second half will look at surgical techniques and considerations whilst the final chapters will address future trends and challenges in the field of knee surgery. This book will be an essential reference for academics, orthopaedic surgeons, and those training in medicine, physiatry and rheumatology.

An increasing percentage of the population has at least one prosthetic joint. Imaging is required for both initial assessment and routine follow-up of the implant, and this book is intended as an informative and up-to-date guide to the subject. After an introductory section covering a range of background topics, the level of information offered by different imaging techniques in presurgical planning and postimplantation assessment is analyzed. The application of imaging to different joints is then carefully explored in chapters devoted to the foot and ankle, hip, knee, shoulder, and elbow, wrist and hand. In addition, two innovative chapters focus on periprosthetic DXA as the gold standard in monitoring implant survival and on the role of drug therapy in helping to ensure the durability of the prosthesis. A central feature of the book is its combination of the clinical and radiological perspectives; it will be of value to radiologists and orthopedic specialists, as well as residents inthese disciplines.

Fully updated reference to clinical knowledge and strategies for effective oral healthcare in frail older adults Taking an evidence-based approach, with theoretical and clinical knowledge underpinned by the literature, Oral Healthcare and the Frail Elder provides a comprehensive reference to management strategies for dental diseases as noncommunicable diseases in older populations. The book presents a global perspective with current guidance for clinicians, addressing the particular challenges of providing dental care for people who are confronting frailty in old age. Reflecting the numerous developments in the discipline since the previous edition was published, this Second Edition has been thoroughly updated throughout with 15 new chapters. The first section covers background information, including demographics, social considerations, and factors affecting oral health in this population. The second half of the book is devoted to clinical management strategies. Some of the new topics discussed in this edition of Oral Healthcare and the Frail Elder include: Theories and significance of oral health in frailty and oral health-related quality of life, and the influence of the life-course on oral healthHow sugar, tobacco, and alcohol initiate and sustain oral diseases, as with other noncommunicable diseases, into old ageMitigation of dental caries, periodontitis, gingivitis, mucositis, and other non-communicable diseases of the mouthInfection control, communications and tele-dentistry, mobile dental services, and strategies to appraise the usefulness of community-based oral healthcare programs With an emphasis on population and public health in the context of non-communicable disease, the Second Edition of Oral Healthcare and the Frail Elder is an important resource for clinicians dealing with the geriatric population, including dentists, dental hygienists, dental therapists, denturists and dental technicians, nurses, and geriatricians.

Compared with primary total hip arthroplasty, revision total hip arthroplasty is challenging due to more complicated pre-operative planning, longer operating time, more blood loss, more uncertainties during operation, and uncertainties in clinical outcome. This book presents up-to-date information on revision total hip arthroplasty covering different failures for primary total hip arthroplasty. Each chapter starts with the principles of diagnosis and treatment of specific THA failure mechanism, and then several typical cases. Each case includes history report, physical examination, laboratory test, radiology, failure mechanism, reconstruction strategy, operation record, post-operative follow-up, tips & tricks, and pitfalls. Written by experts with wealthy of clinical experience, it will be useful reference for arthroplasty surgeons, attending orthopedic surgeons, residents, attendants, and researchers and engineers from orthopedic industry.

This handy and practical book is intended to guide the reader through a correct pre-operative planning in common elective orthopedic procedures. To this aim, it covers arthroplasties and osteotomies of all primary anatomical districts: shoulder, elbow, hip, knee, and ankle. The core idea of the book is that drastic improvements in surgery's outcomes could be obtained following few correct rules. Moreover, correct pre-operative planning helps minimize errors and optimize the time spent in the operating room. Dedicated chapters also explain the importance of patient positioning. Both young practicing orthopedics and residents will find this book an excellent practical guide to the subject.

Understand the core materials that create biomedical innovation Some of the greatest medical advances in recent decades have come in the form of biomedical implants. Whether in the form of traditional orthopedic implants, medical devices for the cardiovascular system, or polymer-based ocular implants, biomedical implants can be lifesaving or life-transforming interventions. The biomaterials which comprise these implants are a vital area of ongoing research, but no prior volume has ever taken comprehensive stock of this subject and its growing applications. An Overview of Biomedical Implants fills this gap with a thorough overview of all major biomaterials and their role in biomedical implants. Composed for an interdisciplinary audience, the book addresses all scales and areas of application. The result is an essential resource in this critical ongoing area of biomedical research. An Overview of Biomedical Implants readers will also find: Description of the relationship between every specific biomaterial and its role in each major implant categoryDetailed discussion of nanoscale to molecular-scale to industrial-scale biomaterialsConcrete examples in every chapter, along with a list of pertinent references An Overview of Biomedical Implants is ideal for physicians, scientists, and engineers—those working in the area of biomaterials, medical, biological and chemical and applied physics, pharmaceutical science and as a reference for professors and students in these areas.

Ectodermal Dysplasias (ED) are a diverse group of genetic disorders characterized by congenital defects of two or more ectodermal structures (e.g., sweat gland, tooth, nail, hair), that count about 100 different manifestations. Therefore, the multidisciplinary aspect is a novel but crucial approach to correctly diagnose and treat this kind of diseases and eventually direct patients to specialized centers. A new classification has been proposed as well as new therapeutic options, such as the first prenatal protein replacement therapy for a genetic disease, X-linked hypohidrotic ectodermal dysplasia. The chapters of this book address all relevant topics, starting with epidemiology and embryology, disease classification, molecular biology, EDA1-associated ED, WNT10A-related ED, and p63-related ED. A chapter on ED caused by defects of structural proteins is included and one specifically devoted to differential diagnoses. Specific chapters describe diagnostic assessments and treatment: odontostomatological signs and therapy, ophthalmological or otorhinolaringoiatric signs, other organ involvement, neurological and neuropsychological issues. The final part is dedicated to the most recent developments in molecular therapy and the extremely important role of parents'and patients'associations. Written by internationally renowned experts, this handy resource will be of valuable help for a variety of specialists who deal with ectodermal dysplasias in their daily clinical work, e.g., pediatricians, dermatologists, ENT-specialists, dentists.

Osteonecrosis is a disease caused by reduced blood flow to bones in the joints, including the hip, knee, shoulder, and ankle. The disease, which is usually progressive and leads to joint failure, occurs in young adults aged from their twenties to their fifties. The pathogenesis of osteonecrosis is still unclear, and treatment remains controversial. This book provides up-to-date and comprehensive information on the pathophysiology, etiology, diagnosis, classification, and treatment of osteonecrosis. The role of various imaging modalities is considered, and both non-surgical and surgical treatment approaches are clearly explained. The contributions, all from experts in the field, are based on presentations at leading international meetings during the past 10 years and on peer-reviewed papers. The book will be of interest not only to clinical practitioners but also to those engaged in basic research.

The knowledge base required of the modern-day head and neck surgeon, as a key member of a comprehensive and wide-ranging multidisciplinary team, is significant. The sixth edition of Stell & Maran's Head and Neck Surgery and Oncology continues to be the leading reference book in the specialty.This accessible and authoritative text is fully revised and updated to reflect international practice across the multidisciplinary team. A global community of expert authors have provided chapters entailing the expertise required by today's head and neck surgeon. The book encompasses fundamentals of head and neck oncologic practice including pathology, imaging, staging, prehabilitation, surgical approaches and reconstruction, radiation therapy, chemotherapy, biological therapies and many more. Key sections discuss the broad range of tumours by anatomical site and rare cancers. Future perspectives are reviewed with topics on how to become a clinical trialist, delivering surgical innovation and personalised approaches to head and neck cancer therapy with insights for the future.With contributions from the full spectrum of the multidisciplinary team, this book will be a major up-to-date resource for both trainees and established practitioners in otolaryngology, maxillofacial surgery, plastic surgery, endocrine surgery, clinical oncology, oncology nursing and those professions allied to medicine, such as speech and language therapy and dietetics.

This book provides comprehensive and up-to-date general information and evaluation of the diagnostic and therapeutic options available to individuals suffering from neurotologic diseases. Neurotology is a fast-developing area of science. Even fundamental terminology, such as the meaning of vestibular symptoms, has only recently been established due to the rapid development of vestibular research. This volume discusses the fundamental sciences, and the clinical application of treatments in neurotology, as well as the most recent research. It is aimed at assisting physicians in making the most effective judgments regarding the management of care for their patients. Diagnosing patients with vestibular symptoms such as vertigo, dizziness, unsteadiness, and oscillopsia requires consideration of symptoms and indicators of neurotologic illnesses. The majority of diagnoses may be made right at the patient's side. A grasp of important diagnostic concepts is vital for all practicing neurologists, who regularly assess whether such patients merit immediate diagnostic testing or hospital admission. This book emphasizes understanding how to take a focused medical history and perform a thorough physical examination on a patient experiencing vestibular symptoms or suspected of having a neurotologic condition. This up-to-date reference should be part of the collections of all otolaryngologists, head and neck surgeons, audiologists, neurologists, neurosurgeons, and residents interested in providing the best possible care for patients.

O uso da tomografia computadorizada Cone Beam (TCCB) na Odontologia é bastante abrangente e vem se tornando cada dia mais difundido. A indicação deste exame para avaliação de implantes e dos tecidos peri-implantares ainda não é um consenso em função dos possíveis riscos inerentes à radiação. Apesar disso, sabe-se que o nível de informação que se obtém é superior aos exames bidimensionais, como radiografia panorâmica e periapical. Independente da indicação, a TCCB é uma ferramenta muito usada e com a qual o radiologista tem contato no seu dia a dia. Sendo assim, mesmo quando a finalidade do exame não é a avaliação de implantes, é comum deparar-se com a presença de implantes nos ossos maxilares. Pensando nisso, esse material foi desenvolvido catalogando as possíveis alterações observadas na implantodontia e exemplificando por meio de imagens.

This book outlines a comprehensive interdisciplinary practice philosophy designed for developing the foundation of optimal diagnosis and treatment planning in implant dentistry. Each chapter will have a comprehensive literature review followed by diagnosis, treatment planning and comprehensive patient case presentations. The goal of modern implant dentistry is no longer represented solely by successful osseointegration. In order to claim success, the definitive restorations must be surrounded by a soft and hard tissue environment in harmony with the existing dentition. This book focuses on analogue and digital workflows from single tooth to full mouth. It discusses the approach of interdisciplinary therapy which involves the combination of knowledge, skills, and experience of all the disciplines of dentistry. Information on the rationale for dental implants and surgical guidelines is provided as well as on the biomechanics of occlusion and the medical evaluation of the implant patient. Subsequent chapters cover treatment planning in the aesthetic zone, impression techniques and scanning, the role of orthodontics in implant dentistry, and screw and cemented restorations. Implant maintenance and failures and complications are discussed in the final part of this book, which is a valuable resource for a wide range of practitioners.

This book is an essential reference guide for the use of artificial intelligence in orthopaedic surgery. It covers all related topics, from machine and deep learning, through practical applications in all orthopaedic sub-disciplines, to ethical issues and potential risks. International renowned experts equip the reader with solid scientific foundations and practical tips combining accurate literature reviews with high-quality original images. Addressing a hot topic for the present and next generation of medical specialists, this book is a must read for orthopaedic surgeons, radiologists and health informatic specialists alike.

SBAs for the Oral and Maxillofacial Surgery FRCS is a question and answer style revision guide designed to help candidates prepare for the Oral and Maxillofacial Surgery (FRCS) Section 1 written exam, and the Tri-Collegiate Membership in Oral Surgery (MOral Surg) exam. Reflecting the format of the exam, the book contains 300 single-best-answer (SBA) questions with detailed explanatory answers. Questions are mapped to the latest curriculum, with key topics weighted according to their relevance in the most recent examinations. An introductory chapter explains the marking methodology used and advises on how candidates can best approach the exam. A revision guide section suggests study topics and recommended reading. Providing a thorough assessment of the key topics and expert guidance, this is an essential resource for higher surgical trainees in Oral and Maxillofacial Surgery looking to maximise their exam success.

This clinical guide, now in an extensively revised second edition, describes the latest developments in planning, materials, and techniques for successful fabrication of removable partial dentures (RPDs). The fabrication of conventional and digital RPDs are demonstrated in a simple and easy-to-understand format, with the aid of numerous color figures and video clips with scientific support on each page. Care has been taken to provide reliable guidance on all aspects of clinical practice relating to RPDs. Readers will find information on decision-making regarding treatment options, clasp-retained RPDs and esthetic solutions, attachments and double crown systems in RPDs, implant-assisted RPDs, maintenance and post-insertion problems for all types of RPDs, the role of RPDs in the management of temporomandibular disorders and the treatment of maxillofacial defects, the re-establishment of occlusal vertical dimension and maximal intercuspation, the rules for disinfection in prosthodontic practice.

MECHANICAL ENGINEERING IN BIOMEDICAL APPLICATIONS The book explores the latest research and developments related to the interdisciplinary field of biomedical and mechanical engineering offering insights and perspectives on the research, key technologies, and mechanical engineering techniques used in biomedical applications. The book is divided into several sections that cover different aspects of mechanical engineering in biomedical research. The first section focuses on the role of additive manufacturing technologies, rehabilitation in healthcare applications, and artificial recreation of human organs. The section also covers the advances, risks, and challenges of bio 3D printing. The second section presents insight into biomaterials, including their properties, applications, and fabrication techniques. The section also covers the use of powder metallurgy methodology and techniques of biopolymer and bio-ceramic coatings on prosthetic implants. The third section covers biofluid mechanics, including the mechanics of fluid flow within our body, the mechanical aspects of human synovial fluids, and the design of medical devices for fluid flow applications. The section also covers the use of computational modeling to study the blockage of carotid arteries. The final section elaborates on soft robotic manipulation for use in medical sciences. Audience The book provides practical insights and applications for mechanical engineers, biomedical engineers, medical professionals, and researchers working on the design and development of biomedical devices and implants.

Comprehensive Materials Processing, Second Edition, 13-vol set, consolidates and enhances the most up-to-date literature of the materials processing and manufacturing universe. It provides authoritative analysis of all processes, technologies, and techniques for converting industrial materials from a raw state into finished parts or products. Coverage encompasses solidification, powder, deposition, and deformation processing. Additional discussion includes plant and tool design, analysis and characterization of processing techniques, high-temperatures studies, and the influence of process scale on component characteristics and behavior. Building and expanding on the previous edition, it includes recent developments and advances in the field, such as updated processing technologies, costs and characterizations. This new edition will also explore sustainability and environmental impact of materials processing in greater detail. Comprehensive Materials Processing, Second Edition will serve as a valuable, one-stop resource to students, academics, and researchers in the fields of engineering and materials science, as well as those in adjacent fields. Industry professionals will also benefit from this comprehensive resource. - Updated to include recent developments in the field, such as updated processing technologies and costs - Explores sustainability and the environmental impact of materials - Includes practical tools such as integrated case studies, user-defined process schemata, and multimedia modeling and functionality - Maximizes research efficiency by collating the most important and established information into one concise resource with consistently formatted chapters

Textbook of Transplantation and Mechanical Support for End-Stage Heart and Lung Disease Comprehensive textbook covering all aspects of the care of patients with advanced heart or lung disease Transplantation and Mechanical Support for End-Stage Heart and Lung Disease is the most comprehensive and contemporary textbook available that addresses the medical and surgical treatment options for patients with end-stage heart and lung disease. All facets of these complex and resource-intensive therapies are covered by leading experts — including the basics of transplant immunology, databases, regulatory and ethical aspects of transplantation and conventional and new modalities of donor organ harvest. Transplantation and Mechanical Support for End-Stage Heart and Lung Disease includes further information on topics such as: Historical developments that facilitated heart and lung transplantation; engineering advances in continuous flow technologies Transplant organizations, oversight, structure, process, databases and registries in the thoracic transplants and MCS field Current strategies in immune modulation, desensitization protocols and mechanisms of allograft rejection and tolerance/immunosenescence Detailed descriptions of donor and recipient surgical procedures as well as comprehensive implantation techniques for all available short- and long-term mechanical circulatory support devices, including ECMO Organ allocation and prioritization, donor evaluation, high risk donors, marginal donors, and risk assessment Richly enhanced with summary tables and color illustrations to provide an engaging and supportive learning experience, the book will serve as a highly valuable source of contemporary knowledge for medical students, residents, nurses, perfusionists, physicians and surgeons involved in the care of these desperately ill group of patients. “This comprehensive book covers all aspects of advanced heart and lung failure treatment, including shock, short-term and durable mechanical assistance, as well as transplantation. The in-depth information will be welcome by newcomers in the field as well as seasoned veterans.” —Andreas Zuckermann, M.D Vice-Chair, Department of Cardiac Surgery, Director of Cardiac Transplantation Program, Medical University of Vienna, Vienna General Hospital “This comprehensive tour-de-force compendium covers practical issues of clinical administration, program development, care pathways, ongoing challenges and opportunities in each treatment area as a must go-to reference for guidance in the rapidly evolving fields of mechanical circulatory support and transplantation.” —Mandeep R. Mehra, MBBS, MSc, FRCP Executive Director, Center for Advanced Heart Disease, Brigham and Women's Hospital, Harvard Medical School “This unique textbook authored by key opinion leaders is a refreshing'wind of change'in our field, one that will well serve all professionals involved in the care of end-stage heart and lung patients for many years to come.” —Marcelo Cypel MD, MSc, FACS, FRCSC Surgical Director Ajmera Transplant Centre at UHN, University of Toronto

Penile Prosthetic Surgery: Practical Guide to Prosthetic Implant describes the different types of penile prostheses and provides step-by-step surgical procedures in diverse patients experiencing erectile dysfunction. Additionally, access to supplemental videos provide enhanced learning through the opportunity to see procedures carried out. Content covers common tips and tricks for successful surgery and presents possible complications with accompanying solutions. Coverage includes full acknowledgement and examinational of the basic research and underling pathological mechanisms that are present in the erectile dysfunction resistant to medical therapy as well as the counseling that patients may need from both the urological and psychological point of view. This book gives a full comprehension of penile prosthesis surgery from multiple viewpoints, making it the perfect reference for urologists, andrologists and psychologists. - Provides step-by-step surgical procedures related to penile prosthesis. - Reviews the complications and possible solutions of this penile prosthetic surgery. - Delivers supplemental videos of the surgical procedures covered in the book help to enhance learning

This well-illustrated book is primarily designed as a practical guide to dental implantology for general dental practitioners who do not routinely place or restore dental implants but also for those who do. It explains the importance of appropriate case selection and treatment planning, examines the risks and benefits of implant care, and discusses immediate placement, immediate loading and delayed placement protocols. Basic surgical and restorative (fixed and removable) options including digital and CADCAM workstreams are outlined. Issues around implant maintenance implant superstructure repair and remakes and implant removal are also covered. This book, written by recognised experts on the subject, will enable dentists with limited implant knowledge to discuss implant procedures with patients and to carry out routine surveillance and repair of dental implants. It will also be of value as a learning aid for under- and postgraduate students.

This second edition text will provide updated information to professionals and students in fields relevant to cochlear implantation. The main objective of this book is to provide the latest information about pediatric candidacy evaluation, medical and vestibular evaluation, surgery, language and literacy outcomes, habilitation, spatial hearing, influence of family dynamics and educational needs. This text also expands upon newer indications including unilateral and asymmetric hearing loss, management of children with residual hearing, and management of children from families whose primary language is Spanish. Additional important new topics discussed include the role of interprofessional training to better serve children, the Australian hearing health care model to achieve early implantation and addressing global barriers to pediatric implantation. Pediatric Cochlear Implantation is ideal for both trainees and practicing otolaryngologists, otologists/neurotologists, audiologists, speech language pathologists, psychologists and educators who work with deaf and head of hearing children.

The aim of our book is to describe the latest developments on aging research methodology, building upon previous editions, and updating the contents. Current topics are to be approached from the research perspective and the underpinnings of those studies aimed at unveiling the fine pathway of aging. The chapters reflect the state-of-the-art methods and their different variations that will clarify problematic issues faced when investigating the impact of time on the biology of live beings (mainly humans). In addition, this work aims to stimulate new questions and innovative approaches from the readers. Finally, content will interest professionals from different disciplines and different levels of expertise.

The book is an assimilation of clinical and practical work done at Tata Memorial Hospital, a prestigious tertiary care cancer hospital in our country. It reflects the evolution of Dental Oncology and Maxillofacial Prosthodontics and more than 33 years of exclusive maxillofacial prosthodontic experience of Dr. Kanchan Dholam. This book covers the clinical guidelines for treatment, based on sound scientific principles and published literature. It also provides a step-by-step approach in the fabrication of commonly-indicated maxillofacial prostheses. It makes an excellent refresher book in Maxillofacial Prosthodontics for all practicing dental post-graduates who want to know more about the subject. The book also contains valuable contributions in Dental Oncology from senior faculty members of the Division of Head and Neck Oncology at Tata Memorial Hospital.This book will be the first Indian/Southeast Asian publication on Dental Oncology and Maxillofacial Prosthodontics. None of the available books have presented a real-world situation of Dental Oncology and Maxillofacial Prosthodontics. This assumes importance in our country wherein the disease presentation is different, cancer treatment is more extensive, and thus the prosthodontic care required, is more challenging and demanding. Apart from the vast socioeconomic difference between patients, the availability of certain materials and techniques is different, which is covered in this book.

This richly illustrated book presents different implant supported overdenture application strategies to help clinicians face a widening range of possibilities in edentulous patients. Edentulism is generally correlated with a functional and esthetic challenge for the patient and brings psychological problems, possibly affecting routine activities. Throughout the book, much attention is devoted to preventive prosthodontics emphasizing the importance of any procedure that can delay or eliminate future prosthodontic problems. Overdenture is an important part of the preventive treatment modality. The introductory chapter of this book explains the theoretical and technical background as well as clinical considerations for overdenture. Different attachment systems for overdentures are then described in detail covering stud attachments, bar attachments, magnetic and telescopic attachments. The final part of the volume focuses on the clinical evaluation parameters of an overdenture treatment, supporting tooth preparation and post treatment protocol. This book is a must have for all clinicians who treat complete denture patients. Two companion volumes covering treatment options before and after edentulism, including tooth supported overdentures and implant supported fixed restorations, are available separately.

While the landscape of implant dentistry is always evolving, one constant is the need for sufficient bone volume at the site of implant placement. The management of bone deficiencies is a clinical challenge with an array of possible solutions, and bone augmentation is not one size fits all. This book simplifies things by presenting the assessment criteria and biologic principles required to make clinical decisions as well as the techniques and materials needed to successfully perform horizontal and vertical bone augmentation. The first several chapters provide the reader with fundamental knowledge of the science of bone augmentation and details the diagnosis and planning phases for bone augmentation surgery. The centerpiece of the text is the Michigan Classification for horizontal and vertical bone augmentation, developed by Drs Hom-Lay Wang and Craig Misch, which offers clinicians an evidence-based decision tree for managing different clinical situations based on the type of defect. Finally, the remaining chapters describe the various techniques for horizontal and vertical bone augmentation, including novel technologies like virtual patient planning for prosthetic guided bone augmentation, customized scaffolds for bone regeneration, and recombinant growth factors to improve regenerative capacity. Written by the most knowledgeable clinicians and researchers in their fields, this book prepares the reader to achieve predictability and success in implant dentistry, no matter the presenting situation.

Skeletally related events make up approximately 20% of the cancer care economy. Advances in understanding the pathobiology and better biotargeted therapy and improved surgical technology are occurring continuously. Hundreds of thousands of patients are living longer with ever-increasing tumor burden, but patients can remain siloed in their care as they navigate across subspecialty treatments. This comprehensive text ties it all together around the patient, integrating all aspects of care.Providing an integrated approach to the diagnosis and management of patients with metastatic bone disease (MBD), this revised and expanded text combines discussion of the pathobiology of the disease with the latest oncological and orthopedic treatment modalities. After opening with an examination of the epidemiology and impact of MBD, the biology of bone metastases are discussed, along with considerations of the tissue of origin, evaluation, biopsy andmedical therapy, including metabolic agents and biotargeting. The heart of the book presents oncological approaches (supportive, radiation and interventional) and principles of orthopedic surgical oncology, with subsequent chapters covering specific anatomy, from the pelvis to the lower extremity and the spine. Chapters on emerging surgical technology and future directions conclude the text. New to this edition are considerations around patient-reported outcomes. Utilizing the latest clinical evidence and treatment techniques, Metastatic Bone Disease, Second Edition is standalone resource reflecting a comprehensive, patient-centric resource for all types of providers.

Dental implant placement often requires bone grafting to ensure sufficient bony support for the implants being placed. Depending on the biologic conditions of the patient, including the level of bone atrophy and the status of the remaining teeth in the mouth, more adjunctive procedures like bone harvesting or sinus grafting may be required. This book covers it all, from the biology of bone and how dental implants work within that framework to the many procedures for harvesting bone and using it to augment sites for implant placement. The different types of bone grafts and membranes are discussed as well as procedures to preserve the alveolar ridge following tooth extraction. Dr Garg was a pioneer in dental bone grafting, and this new edition keeps him at the forefront of the field.

50 Studies Every Orthopaedic Surgeon Should Know is a compilation of landmark studies from all subspecialties within emergency and elective Trauma and Orthopaedic practice. It is written in an accessible way, appropriate for an array of practicing experts, allied healthcare professionals and students with the goal of disseminating findings from high-quality studies that have led to standardized clinical guidelines for front-line clinicians and real-world gains for patients. Chapters focus on key findings, implications for practice, study funding sources, conflicts of interest, criticisms and limitations, and results from associated studies. Each chapter also concludes with a case study, offering readers the opportunity to conceptualize the key findings in practice. Like other books in the 50 Studies series, an objective selection criterion was conducted by an international consensus to identify the most influential landmark publications, taking into account the citations per year, high levels of evidence, clinical studies and trials as well as available references and guidelines. This book will simplify, consolidate and reinforce the current literature of the most important research published into in a digestible, manageable, and reader-friendly content for Trauma and Orthopaedic Surgeons, practicing clinicians, trainees, students and those led by data-driven evidence-based clinical care.

Tribological Aspects of Additive Manufacturing provides a technical discussion on the roles of the 3D printing process in processing polymeric-, metallic-, and ceramics-based additive manufactured products in order to improve the tribological properties. It explores design flexibility, waste minimization, and cost reduction.Emphasizing the various types of additive manufacturing technologies, this book demonstrates how these can effectively influence the tribological properties of additively manufactured components. It examines 3D printing process parameters, carbon fiber reinforcement, natural fiber reinforcement, and surface structure on tribological properties of 3D-printed parts. This book also covers wear and friction resistance of additively manufactured parts prepared with natural fiber and carbon fiber.This book will be a useful reference for undergraduate and graduate students and academic researchers in the fields of materials science, tribology, additive manufacturing, maintenance engineering, and 3D printing.

This book presents cutting-edge research and developments in the broad field of medical, biological engineering and computing. It gathers the second volume of the joint proceedings of the Mediterranean Conference on Medical and Biological Engineering and Computing (MEDICON) and the International Conference on Medical and Biological Engineering (CMBEBIH), which were held together on September 14-16, 2023, in Sarajevo, Bosnia and Herzegovina. Contributions report on innovative research and practices in molecular biology, tissue engineering and biotechnologies, covering not only medical but also industrial applications. Further, they describe advances in health technologies and medical devices, telemedicine, and robotic applications in clinical medicine and rehabilitation.

For over 40 years, Yen & Jaffe's Reproductive Endocrinology has been the gold standard text of both basic science and clinical practice of the full range of female and male reproductive disorders. The fully revised 9th Edition continues this tradition of excellence with complete coverage, including up-to-date information on impaired fertility, infertility, recurrent pregnancy loss, problems of sexual development, menstrual disturbances, fibroids, endometriosis, female and male reproductive aging, fertility preservation, assisted reproduction technologies including ovarian stimulation and ovulation induction, transgender hormonal treatment, contraception, and more. An outstanding editorial board and other global experts in the field share their knowledge and expertise to keep you abreast of current science and practice in endocrinology. - Includes new chapters on Meiosis, Fertilization and Embryo Development; Recurrent Pregnancy Loss; Uterus Transplantation; Mitochondrial Transplantation and Gene Editing; and Germs Cells Developed In Vitro. - Provides extensively revised information on contemporary practices in assisted reproduction, fertility preservation, and ovulation induction. - Provides an online video library that highlights surgical procedures, diagnostic imaging, and functional ultrasound imaging. - Adds three new members to the exceptional editorial team: Drs. Anuja Dokras, Carmen J. Williams, and Zev Williams. - Features full-color, high-quality illustrations that clearly depict basic anatomic structures, endocrine processes, and cell function and dysfunction. - Includes bulleted lists under major headings in each chapter for quick, at-a-glance summaries of every section. - Lists Top References at the end of each chapter that distill the most important references for research underpinnings, to complement the complete online reference list. - An eBook version is included with purchase. The eBook allows you to access all of the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud.

In this comprehensive review guide, all areas of oral and maxillofacial surgery are covered in the form of over 1,700 multiple-choice questions. Detailed answers follow that help to explain and contextualize the question and its clinical relevance, with accompanying illustrations where necessary to aid understanding. The book is separated by topic and specialty, beginning with anatomy and working through anesthesia/pharmacology, cleft lip and palate, cosmetic procedures, craniofacial surgery, dental implants and dentoalveolar surgery, infection and pathology, medicine, orthognathics, reconstructive surgery, TMJ, and trauma, so readers can study it in its entirety or focus on one area at a time. Written by the head of a regional exam committee for OMFS boards, this book can help to prepare readers for board examination as well as serve as a refresher for practicing oral surgeons to review their craft.

This book provides comprehensive, evidence-based surgical principles and techniques for total hip arthroplasty (THA), covering all aspects of this procedure, including the history, biomaterials, biomechanics, surgical techniques and other important issues. Beginning with an overview of the hip joint and its anatomy, the authors detail the biomechanics of the hip joint in its various states and further discuss the properties of biomaterials in arthroplasty. The book describes the principles of surgical technique, preoperative planning, surgical procedures, rehabilitation, and management of complications, and thoroughly illustrates surgical procedures to enhance the reader's understanding. The book also introduces the technical aspects of the procedure, including how to deal with difficult cases such as severely deformed cases and how to increase the safe range of motion. Advances in Total Hip Arthroplasty is written by a pioneering team of authors in cooperation with the Japanese Society for Replacement Arthroplasty (JSRA). The book is informative and provides practical tips for THA and academic insights for orthopedic surgeons and residents specializing in arthroplasty. The translation was done with the help of an artificial intelligence machine translation tool. A subsequent human revision was done primarily in terms of content.

This book brings together a comprehensive set of chapters that cover the basic principles of fast track surgery, clinical enhancements, but also important aspects of project management and change management in Hip and Knee Arthroplasty. Although the value of care pathways and fast track surgery are probably well known by almost everyone, there are still too many differences in arthroplasty care not only around the world, but also within countries. How can it be that the fast track principles are implemented so poorly? Probably because it looks so simple, yet it's so complex that many doctors don't know where to start. This handy book, published in collaboration with ESSKA, provides an easy-to-consult guide that summarize the most important notions in a concise, accessible way.

This comprehensive resource explains the FDA's classification of devices and provides expert guidance on differentiating between significant risk and non-significant risk medical device studies. The book is divided into two parts: Significant Risk Medical Devices and Non-Significant Risk Medical Devices. Each chapter includes a general introduction and overview of the device, along with guidance on its working principles, beneficial and toxicological effects, and potential risks to the health and safety of a patient/subject. The coverage also includes reports of prior investigations on the basics of risk determination and the nature of potential harm associated with using individual devices.Significant and Non-Significant Risk Medical Devices is designed to assist practicing engineers, academic researchers, and clinical investigators in navigating the complex regulatory environment associated with medical device research and development.

This book covers advancements in the field of bone repair and regeneration. It introduces bone development, repair, and regeneration and details different biomaterials and technologies involved in the fabrication and characterization of bone-related scaffolds and implants. The book explores nanotechnological intervention and folklore phytomedicines and their prospects in regenerating bone including major bone related disease conditions, infection, and their tackling via tissue engineering strategies.FEATURES: Covers polymer materials and technologies for bone repair and regeneration based on tissue engineering Defines the interdisciplinary mechanism of bone tissue repair ranging from the fields of material science, nanotechnology, and phytomedicine includes basic sciences, scaffolds, and bone infection Examines fabrication and characterization methods for the bone repair materials Reviews fundamentals of interlinked mechanisms of bone development, repair, and regeneration. This book is aimed at graduate students and researchers in biomedical and tissue engineering and biomaterial sciences.

A Practical Guide to Planning, Writing, and Reviewing Medical Device Clinical Evaluation Reports guides readers through clinical data evaluation of medical devices, in compliance with the EU MDR requirements and other similar regulatory requirements throughout the world. This book brings together knowledge learned as the author constructed hundreds of CERs and taught thousands of learners on how to conduct clinical data evaluations. This book will support training for clinical engineers, clinical evaluation scientists, and experts reviewing medical device CERs, and will help individual writers, teams and companies to develop stronger, more robust CERs.Identifies and explains data analysis for clinical evaluation of medical devicesTeaches readers how to understand and evaluate medical device performance and safety in the context of new regulationsProvides analysis of new clinical evaluation criteria in the context of medical device design as well as in-hospital deployment and servicing

Essentials in Total Knee Arthroplasty is a succinct, yet comprehensive book that provides a unique look into the world of total knee arthroplasty (TKA), beginning with an in-depth history of this common procedure, and then progressing to strategies that will manage, treat, and prevent complications.Inside the pages of Essentials in Total Knee Arthroplasty, Dr. Javad Parvizi and Dr. Brian Klatt, along with more than 40 contributors, cover a wide-range of topics, including: Knee biomechanics and biomaterials Surgical approaches to TKA Postoperative Analgesia Options for the Total Knee Arthroplasty Patient Controversies in TKA Mechanisms of failure in TKA Complex primary total TKA TKA revision TKA rehabilitation With over 100 color images, clear & descriptive text, and a forward thinking approach to clinical and basic research in the reconstruction of the knee, Essentials in Total Knee Arthroplasty will become the'go-to'book for orthopedic residents, fellows, junior attendings, medical students, and physical therapists involved with all matters related to total knee arthroplasty.

This new edition elucidates the radiation therapy protocols and procedures for the management of adult patients presenting with primary benign and malignant central nervous system tumors. With the development of new treatment strategies and rapid advancement of radiation technology, it is crucial for radiation oncologists to maintain and refine their knowledge and skills. Dedicated exclusively to adult CNS radiation oncology, this textbook explores CNS tumors ranging from the common to the esoteric as well as secondary cancers of metastatic origin. The first half of the book is organized anatomically: tumors of the brain, spinal cord, leptomeninges, optic pathway, ocular choroid, and skull base. The second half covers primary CNS lymphoma, rare CNS tumors, metastatic brain disease, vascular conditions of the CNS, radiation-associated complications, and radiation modalities. This new edition is updated throughout and includes several new chapters, including: palliative radiation therapy for leptomeningeal disease, preoperative treatment for brain metastases, advanced neuroimaging for brain tumors, and MR-LINAC for brain tumors. Each chapter provides guidance on treatment field design, target delineation, and normal critical structure tolerance constraints in the context of the disease being treated. Learning objectives, case studies, and Maintenance of Certification Self-Assessment Continuing Medical Education-style questions and answers are incorporated throughout the book. This is an ideal guide for radiation oncologists, residents, and fellows, but medical students may also find value in the text.

This book provides short chapters with key learning points from experts within the area, about musculoskeletal conditions in patients with obesity. Each chapter will be structured in two parts: (a) the increasing musculoskeletal conditions caused by the obesity and (b) the difficulty of treating the musculoskeletal conditions in the presence of obesity. It is aimed at a multidisciplinary readership including clinicians, physiotherapists, rehabilitation specialists, general practitioners and sports physicians, and other allied health professionals involved in the treatment of musculoskeletal disorders.

Over the past 20 years, dental implants have become one of the most common surgical procedures in the treatment of oral cavities, for example for replacing lost teeth. This book outlines aspects of dental implantation in both the surgical and prosthetic stages of treatment. The book covers materials that are used in implantology, bone guided regeneration, structure and surface implants, classification of implants, osseointegration, surgical stages of dental implantation, classification of quality and quality of bone, bone graft therapy before dental implantation, and complications in dental implants. The reader is guided through the process of using digital tools at every stage of treatment, from developing the treatment plan to surgical execution, and information is provided on choosing patients, evaluating host sites, selecting implant types, instituting remedial techniques, performing a wide variety of restorative modalities, and maintaining and following up with patients during the postoperative period. The reader is guided through the process of using digital tools at every stage of treatment, from developing the treatment plan to surgical execution, and information is provided on choosing patients, evaluating host sites, selecting implant types, instituting remedial techniques, performing a wide variety of restorative modalities, and maintaining and following up with patients during the postoperative period.

This book provides an easy-going, high-quality and updated work focused on the most common diagnoses of Traumatology and Orthopaedics. It's structured with several sub-headings, including bullet-point tips for basic concepts.Each chapter is focused on a specific pathology and includes the following sub-headings: short introduction, applied anatomy and physiology, prevalence, classification, diagnosis (including anamnesis, physical examination and complementary imaging, from plain x-ray to cross-sectional imaging), treatment (conservative-surgical options), controversies, complications, future directions and author's preference for treatment apart from references. Orthopaedics and Trauma - Current Concepts will be an inspiration to the young orthopaedic resident, fellow or even general orthopaedic surgeon and senior medical student. It will definitely help with their careers and also be a useful tool to prepare for the board certified orthopaedic examination.

This atlas aims to provide the reader with comprehensive and structured knowledge of contemporary head and neck surgical procedures in patients with both benign and malignant diseases. The bulk of the atlas is devoted to the surgical management of malignant tumors of the upper aerodigestive tract, with a separate chapter focusing on each major anatomic subsite. All aspects of endoscopy are covered, as is surgery of the upper airway, including tracheostomy, laryngotracheal reconstruction and surgery for vocal cord paralysis. Thorough consideration is also given to procedures for the treatment of carotid body tumors, branchial arch anomalies, deep neck space infections, pharyngeal pouches, and benign disease of the thyroid, parathyroid, and salivary glands. A final chapter addresses in detail the reconstruction of surgical defects in the head and neck. Each chapter includes bespoke drawings and diagrams to illustrate specific technical points and surgical steps. The authors are leading head and neck surgeons from Europe, North America, India, Africa, and Australia. Readers seeking a better understanding of how to carry out surgical procedures in this anatomic region will find the atlas to be an invaluable aid.

Comprehensive, multidisciplinary approach to all aspects of dental implant maintenance, based on treatment outcomes Saving Dental Implants offers a complete reference to all factors in long-term success in dental implants. Taking an interdisciplinary approach, each chapter is written by leading experts in the field. The book examines treatment outcomes, provides advice on how to manage implants for long-term success, and supports clinicians in avoiding and managing peri-implant complications. The text presents global treatment approaches and concepts—established philosophies in practice for the last 20 years—and also looks to possible future management strategies. Designed to help clinicians apply the concepts in practice, the text also covers the pros and cons of implant therapy and the specifics of pre-implant diagnostics, treatment methodology, prosthetic concepts, and further maintenance visits. Featuring hundreds of high-quality color photographs to support the text, Saving Dental Implants covers topics such as: The anatomic features of peri-implant tissues, including clinical and histological information, and an evaluation of the studies using different implant systems and prosthetic concepts Diagnostic tools and procedures to make the proper diagnosis of peri-implant conditions, and microbiota of the peri-implant tissues and diagnostic opportunities for bacterial diagnosis Nanoparticles found in the peri-implant tissues from the implant placement, their loading, and their impact on peri-implant diseases The significance, applications, and limitations of bone grafting techniques to optimize the shape of the alveolar ridge New technologies for better treatment of peri-implant complicationsExamining the most current information and research on diagnosing, preventing, and managing peri-implant complications, Saving Dental Implants is a must-have practical reference for dental practitioners, specialists, and students who wish to help patients reach the best functional and esthetic outcomes.

The text covers fundamentals and technological advancements in processing, post-processing, and surface engineering of bioimplant materials. It further discusses important topics such as the additive manufacturing of bioimplants, the tribological performance of bioimplants, and the hybrid and non-traditional manufacturing of bioimplants materials. The text also presents the latest advancements in intelligent bioimplant manufacturing using artificial intelligence and machine learning.This book: Offers an in-depth understanding of the fundamentals, types, materials and applications of bioimplants Highlights the effect of processing on microstructure, biocompatibility, and mechanical behavior of bioimplants Investigates the surface modification methods and tribological performance of bioimplants Discusses additive manufacturing and non-traditional manufacturing techniques such as electrical discharge machining and electrochemical machining of bioimplants materials Covers smart technologies such as artificial intelligence and machine learning-based intelligent implant manufacturing for Industry 4.0 It is primarily written for senior undergraduate and graduate students and academic researchers in the fields of mechanical engineering, biomedical engineering, production engineering, industrial engineering, aerospace engineering, and manufacturing engineering.

Comprehensive Hematology and Stem Cell Research is the first major reference to cover both stem cell research and therapy as well as the range of hematological disorders they are currently used to treat and may potentially be able to treat in the future. This five volume set includes fundamentals, such as the underlying mechanisms of the blood and immune system, highlighting blood disorders and cancers of the blood, including lymphoma, leukemia, and myeloma. Other sections cover stem cell research and therapy, from harvesting stem cells to their utilization in cancer treatments.Finally, the work looks to the future and explores newer stem cell research that may lead to future treatments. This book is an excellent resource for students at the graduate and post-graduate levels, academics, and researchers in the fields hematology, immunology and oncology. - Compiles foundational knowledge and breakthrough research into one concise, comprehensive reference - Takes a translational, bench-to-bedside approach to hematological disorders and stem cell therapies - Covers clinical applications of stem cells, advances in the field, and promising new research

Joint Replacement in the Human Body provides a comprehensive exploration of artificial joint designs. The book's primary focus is to introduce readers to the diverse landscape of artificial joint technologies while offering insights into their historical development. This book is divided into three sections, each addressing specific aspects of joint replacements. The first section delves into artificial joints of the lower limb, including the hip, knee, and ankle. In the subsequent section, the book explores upper limb replacements, covering joints such as the shoulder, elbow, wrist, finger, and thumb.The third section tackles broader themes like biotribology, regulatory aspects of joint replacements, examines noteworthy case studies like metal-on-metal hips, and addresses joint replacements not easily categorized in the previous sections, such as spinal total disc replacements. This book offers a critical assessment of the diverse and evolving design concepts currently in use, ranging from established metal-on-polymer joints to innovative biomimetic solutions. This book is designed to swiftly equip readers with a deep understanding of contemporary joint replacements and the immediate and long-term challenges they present. - Covers all the joints that are replaced in the human body, including the hip all the way to the toes - Provides a thorough examination of vastly diverse implanted design concepts, ranging from the established metal-on-polymer approach to innovative biomimetic designs - Describes joint biomechanics and their corresponding replacements, followed by a description of future challenges appropriate to each joint and current debates

With its comprehensive, global coverage of all aspects of diagnosis, screening, and treatment in both adults and children, Firestein & Kelley's Textbook of Rheumatology remains your reference of choice in this evolving field. The fully revised 12th Edition retains the user-friendly, full color format, providing in-depth guidance in rheumatology with an ideal balance of basic science and clinical application. New editors, new chapters, and new illustrations keep you fully up to date on recent advances in genetics and the microbiome, current therapies, and other rapid changes in the field. - Covers everything from basic science, immunology, anatomy, and physiology to diagnostic tests, procedures, physical examination, and disease pathogenesis, manifestations and treatment?including key data on outcomes to better inform clinical decision making. - Includes new or significantly revised chapters on Pre-Clinical Autoimmunity; The Microbiome in Health and Disease; Physical Therapy and Rehabilitation; Nutrition and Rheumatic Disease; Classification and Epidemiology of Spondyloarthritis; Etiology and Pathogenesis of Osteoarthritis; COVID and Rheumatic Disease; Vaccination in Rheumatic Disease; Autoimmune Complications of Immune Checkpoint Inhibitors for Cancer; and many more. - Features 1,200 high-quality illustrations, including superb line art, quick-reference tables, and full-color clinical photographs; many new illustrations highlight diseases among racially diverse patients. - Shares the knowledge and expertise of internationally renowned scientists and clinicians, including new editors Drs. Ted Mikuls and Tuhina Neogi. - Demonstrates the complete musculoskeletal exam in online videos, including abnormal findings and the arthroscopic presentation of diseased joints.

This clinical atlas is a comprehensive reference work on bone and joint disorders that can be characterized and assessed with hybrid bone SPECT/CT. It is structured according to the major joints and regions of the skeletal system, including spine, shoulder and elbow, hand and wrist, pelvis and hip, knee, and foot and ankle. For each region, the annotated normal X-ray and cross-sectional anatomy is presented, followed by a general introduction to the most common pathologies and frequent surgical procedures. Optimal bone SPECT/CT acquisition parameters are summarized and pre- and postoperative conditions are then discussed with the aid of informative clinical case vignettes featuring not only bone SPECT/CT images but also correlative findings on other imaging modalities. For every case, teaching points highlighting need-to-know findings and common pitfalls are presented. The book concludes with two dedicated chapters covering bone SPECT/CT imaging in sports injuries and oncology. Featuring many high-quality illustrations, Clinical Atlas of Bone SPECT/CT will be an invaluable resource for all nuclear medicine physicians. It is published as part of the SpringerReference program, which delivers access to living editions constantly updated through a dynamic peer-review publishing process.