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A New Era in Alzheimer's Research: Pathogenesis, Prevention, and Treatment is focused on the research and perspectives in Alzheimer's disease (AD), offering an update on the challenging aspects of neurodegenerative disorders. Each chapter of this book contains unique and valuable scientific information on the latest progress of research in neurodevelopmental diseases. Even after years of research, Alzheimer's disease is still far from being cured; this book addresses the most current issues within the many dimensions relevant to the pathogenesis, diagnosis, and prevention under one cover, making it useful for researchers, students, and clinicians, as well as those in pharmaceuticals. - Contains basic knowledge about Alzheimer's disease and its causes and related pathology for a better understating of AD - Provides the multidisciplinary research on Alzheimer's disease in one source - Uniquely describes the details of the pathological, diagnostic, and preventive information for the potential development of novel anti-AD drugs - Includes hot topics, such as cerebrovascular pathology and lifestyle medicine, for the prevention of AD

Handbook of Sourdough Microbiota and Fermentation: Food Safety, Health Benefits, and Product Development links the cereal and sourdough-based microorganisms, fermentations and microbial metabolites with food hygiene and safety, functional and health promoting properties, and their potential interest to be employed in the agro-food sector and beyond. Structured in a way that provides the latest findings and most recent approaches and trends on sourdough this book also emphasizes the biotechnological aspects, such as fermentation, food processing and the use of beneficial microorganisms and their metabolites in different ways and in different industries. Written by experts from a multidisciplinary perspective, this book is a remarkable reference to a wide range of audiences with different backgrounds, from academics and researchers in food science to industrial food engineers and technicians, food plant managers, and new product and processing developers/managers in food packaging and preservation. - Covers how cereal-based and sourdough microorganisms and microbial metabolites can be used to extend the shelf-life of bread and other agro-food products - Presents microbial safety, fermentations, ropiness of baking-based products, bacterial and mold food spoilage, and the health promotion of sourdough and cereal-based products - Describes how cereal and sourdough-based products can contribute to convenient, nutritious, stable, natural, low-processed and healthy food

In the age of digital transformation, the tourism industry faces a pressing challenge: balancing the growing demand for travel with the imperative to protect the environment and preserve local cultures. The rise of digital platforms has revolutionized how people plan, book, and experience travel, but it has also intensified concerns about overtourism, cultural commodification, and environmental degradation. Without thoughtful intervention, these trends threaten to undermine the destinations travelers seek to explore. Promoting Responsible Tourism With Digital Platforms offers a comprehensive solution by exploring how digital platforms can be leveraged to promote responsible travel practices. By examining case studies, theoretical frameworks, and the latest technological advancements, the book provides actionable insights for policymakers, industry professionals, and travelers alike. It serves as a roadmap for integrating responsible tourism principles into the digital landscape, ensuring that tourism remains sustainable and beneficial for all stakeholders. The book explores sustainable destination management, community engagement through social media, and blockchain technology for ethical tourism practices. It equips readers with the knowledge and tools needed to navigate the complex intersection of responsible tourism and digital platforms. Promoting a deeper understanding of these issues, Promoting Responsible Tourism With Digital Platforms aims to foster a more conscientious and sustainable approach to travel, ensuring that future generations can continue exploring the world's wonders without compromising the integrity of local communities and ecosystems.

Persistent and non-degradable, heavy metals stand as pollutants with the potential for severe ecological repercussions when released into the environment. Municipal and industrial wastewater face a high risk of contamination by these hazardous substances, posing a formidable challenge to water treatment technologies. The imperative is clear: effective and affordable methods for effluent treatment and metal recovery are essential for meeting regulatory standards and unlocking the latent value of valuable metals within the waste. However, new methods of accomplishing this challenge are necessary for increasing the effectiveness in both cost and application Biosorption Processes for Heavy Metal Removal comprehensively explores the imperative to remove heavy metals from waste streams. It provides an insightful overview of biosorbents and biosorption technology, focusing on their underlying biosorption features. Biosorption, an intrinsic property of living and deceased biomass, is a crucial mechanism for the swift binding and concentration of organic and inorganic compounds from dilute aqueous solutions. In wastewater treatment, biosorption involves utilizing biosorbents derived from non-living biomass to extract target substances from polluted water selectively. Harnessing microorganisms such as bacteria, algae, yeasts, and fungi as biosorbents for heavy metal removal has gained traction due to their advantageous characteristics, including a high surface-to-volume ratio, widespread availability, rapid kinetics of adsorption and desorption, and low cost. The compilation within this book comprises of a series of review articles delving into the current understanding of biosorption mechanisms and biochemistry, the efficacy of bacterial, fungal, and algal biomass, and practical considerations for biosorbent preparation and engineering. The physicochemical evaluations of biosorbents, process optimization, and factors influencing biosorption efficiency are also covered. Furthermore, the book explores biosorption applications for removing nutrients, organic pollutants, and metals in wastewater treatment across diverse contexts. Geared towards administrators, policymakers, consultants, industry professionals, academicians, scientists, researchers, and graduate and post-graduate students in environmental sciences and related fields, this book serves as their comprehensive reference. It caters to a broad spectrum of fields, including environmental safety engineering, and research and development programs focused on advancing biosorption research and developing industrial applications for heavy metal separation technologies. Wastewater treatment plant operators, those involved in sludge treatment and disposal, and researchers and students in environmental engineering will also find this book to be of significant interest.

Ist die globale Nahrungsmittelproduktion ausreichend, um die Ernährungssicherung für alle Menschen zu gewährleisten? Und kann sie es auch in Zukunft sein? Welcher Zusammenhang besteht zwischen Landwirtschaft und Klimawandel? Wo liegen die Ursachen für Fehlernährung und in welchen Ländern herrschen Mangel oder sogar Überfluss? Ausgehend von der erwarteten Zunahme der Weltbevölkerung beschreibt dieses Fachbuch die derzeitige Ernährungslage, die Ernährungserfordernisse (Kalorien- und Proteinbedarf) und listet unterschiedliche Methoden auf, die den Grad der Unterversorgung bestimmen, wie z. B. den Welthungerindex. Daran anschließend wird der Selbstversorgungsgrad verschiedener Länder vorgestellt und die Gefahren und Chancen von Landgrabbing erörtert.Ein besonderer Fokus liegt auf den Produktionsmitteln der Nahrungsmittelerzeugung und deren zukünftige Entwicklung: Boden, Klima, Wasser, Düngung, Pflanzenschutz, Mechanisierung der Landwirtschaft. Zudem werden wichtige pflanzliche und tierische Nahrungsmittel nach globalen Produktionsmengen vorgestellt sowie unterschiedliche landwirtschaftliche Produktionsmethoden beschrieben. Fachkräfte im Bereich der Entwicklungszusammenarbeit, in NGOs, internationalen Organisationen und ernährungspolitischen Verbänden bietet dieses Fachbuch eine detaillierte Zusammenstellung an Zahlen, Daten und Fakten zur globalen Ernährungslage. Studierende der Agrar- und Ernährungswissenschaften erhalten Einsicht in die komplexen Zusammenhänge zwischen wirtschaftlicher und demografischer Entwicklung, Agrarsystemen und internationaler Ernährungssicherheit.

This book presents modern trends that regard the utilization of advanced functional materials for the development of innovative pharmaceuticals. Such materials include classes of lipids, polymers, proteins, and peptides, as well as inorganic materials, which find application in nanomedicinal products, drug delivery systems, medical devices, biotechnological products, and several other technologies. These products are promising for the therapy and diagnosis of diseases. Special attention is given to the available analytical techniques utilized for the evaluation of materials, their interactions, and their properties as well as the functionality of the final pharmaceutical forms. In addition, scale-up opportunities and limitations of nanomaterials and the current and emerging challenges in their clinical translation, with reference to relative regulatory aspects, are discussed. The book covers the latest advances in functional materials for biomedical applications and will serve as a guide for the industry and aid future research. It will be useful for upper undergraduate students and graduate students, young researchers (in the fields of pharmaceutics and materials sciences), scientists who want to enrich their knowledge on advanced drug delivery nanocarriers and their applications, researchers in the Big Pharma and readers who want to learn more about the role of nanoscience in the design and development of nanomedicines.

Density Functional Theory (DFT) first established it's theoretical footing in the 1960s from the framework of Hohenberg-Kohn theorems. DFT has since seen much development in evaluation techniques as well as application in solving problems in Physics, Mathematics and Chemistry.This review volume, part of the IMS Lecture Notes Series, is a collection of contributions from the September 2019 Workshop on the topic, held in the Institute for Mathematical Sciences, National University of Singapore.With contributions from prominent Mathematicians, Physicists, and Chemists, the volume is a blend of comprehensive review articles on the Mathematical and the Physicochemical aspects of DFT and shorter contributions on particular themes, including numerical implementations.The book will be a useful reference for advanced undergraduate and postgraduate students as well as researchers.

This handbook is a comprehensive, systematic source of modern nuclear physics. It aims to summarize experimental and theoretical discoveries and an understanding of unstable nuclei and their exotic structures, which were opened up by the development of radioactive ion (RI) beam in the late 1980s. The handbook comprises three major parts. In the first part, the experiments and measured facts are well organized and reviewed. The second part summarizes recognized theories to explain the experimental facts introduced in the first part. Reflecting recent synergistic progress involving both experiment and theory, the chapters both parts are mutually related. The last part focuses on cosmo-nuclear physics—one of the mainstream subjects in modern nuclear physics. Those comprehensive topics are presented concisely. Supported by introductory reviews, all chapters are designed to present their topics in a manner accessible to readers at the graduate level. The book therefore serves as a valuable source for beginners as well, helping them to learn modern nuclear physics.

Progress in Heterocyclic Chemistry: Volume 34, the latest in this annual review series commissioned by the International Society of Heterocyclic Chemistry (ISHC), contains both highlights of the previous year's literature on heterocyclic chemistry and articles on new developing topics of particular interest to heterocyclic chemists. Highlight chapters in Volume 34 are all written by leading researchers in their field, thus constituting a systematic survey of the important original material reported in the literature of heterocyclic chemistry in 2021. As with previous volumes in the series, Volume 34 will enable academic and industrial chemists and advanced students to keep abreast of developments in heterocyclic chemistry in a convenient way. - Recognized as the premiere review of heterocyclic chemistry - Includes contributions from leading researchers in the field - Provides a systematic survey of the important 2021 heterocyclic chemistry literature - Presents articles on new and developing topics of interest to heterocyclic chemist

The brain is crucial for the regulation of whole-body metabolism and behavior. The pancreas-derived hormone insulin modulates brain function and affects energy metabolism as well as cognition. This is partially achieved by modulating several types of brain cell populations including those relevant to satiety and reward. Importantly, brains of Alzheimer´s disease patients exhibit a signature of brain insulin resistance with perturbed brain metabolism. This book will cover the basics of insulin signaling in the brain and will describe concepts of insulin resistance, a feature of type 2 diabetes. Moreover insulin´s effect on cognitive function will be pointed out and the association between brain insulin resistance and neurodegenerative diseases discussed. Additionally, potential behavioral and pharmacological concepts which can affect brain insulin signaling will be summarized.Key Features: Summarizes insulin and the closely related IGF-1 receptor signaling Depicts concepts of insulin resistance Highlights the importance of conserved brain insulin signaling for brain function, metabolism, and behavior Describes potential behavioral and pharmacological approaches to support brain insulin signaling

Boron has long occupied a privileged role in chemistry (as a catalyst component) and human health (as a micronutrient). In 1951, boron science took a momentous leap forward with its application in clinical cancer research. The seventy or so years since have witnessed exciting developments in the technology now known as Boron Nuclear Capture Therapy (BNCT), a binary form of radiotherapy that lethally combines two separately non-lethal constituents: a boron-based radiosensitizer and non-ionizing neutron radiation. Frontiers in Boron-based Medicinal Chemistry is a one-stop resource on the current state of BNCT and promising works in the pipeline. It begins with an introduction to general boron chemistry, with extensive discussion on important boron compounds including boranes, boronic acids, carboranes, and FDA-approved boron drugs. Chapter 2 looks at BNCT in clinical trials, while Chapter 3 describes emerging next-generation agents such as boron-based nanoparticles and dendrimers. The penultimate chapter summarizes the currently used and emerging imaging techniques in BNCT, namely, PET, CT, MRI and fluorescence microscopy. The book concludes with a technically heavy chapter on neutron sources and dosimetry. The cutting-edge information contained in this authoritative volume will be a valuable resource for all those involved in mankind's endless struggle against cancer.

This textbook presents the principles and methods for the measurement of radioactivity in the environment. In this regard, specific low-level radiation counting and spectrometry or mass spectrometry techniques are discussed, including sources, distribution, levels and dynamics of radioactivity in nature. The author gives an accurate description of the fundamental concepts and laws of radioactivity as well as the different types of detectors and mass spectrometers needed for detection. Special attention is paid to scintillators, semiconductor detectors, and gas ionization detectors. In order to explain radiochemistry, some concepts about chemical separations are introduced as well. The book is meant for graduate and advanced undergraduate students in physics, chemistry or engineering oriented to environmental sciences, and to other disciplines where monitoring of the environment and its management is of great interest.

This book presents an authoritative review of analytical methods used for diagnostics, medical therapy and for forensic purposes. Divided into 4 parts, the book discusses new challenges in bioanalytics, covers bioanalysis as a source of clinical, pharmaceutical and forensic information, explores natural resources as a source of biologically active compounds, and offers new analytical strategies and equipment solutions. Written by interdisciplinary expert academics, this work will appeal to a wide readership of students, researchers and professionals interested in the fields of medicine, chemistry, pharmaceutical, life and health sciences, engineering and environmental protection. Clinicians and employees of forensic laboratories will also find this work instructive and informative.

This book is a practical guide for advocates interested in the representation of victims before the International Criminal Court (ICC). It has been developed by experts responsible for the advocacy training of the International Criminal Court's List of Counsel members. Written in a readily accessible style, this guide provides a firm grounding in relevant legal doctrine, essential advocacy techniques and valuable multidisciplinary perspectives. Drawing upon global expertise from legal practitioners, specialist advocacy trainers and multi-disciplinary writers, this book addresses both practical considerations and key challenges faced by ICC victim advocates. These include issues such as gender, child victims, victims of sexual violence, special need victims and victims who are themselves implicated in international crimes. Through its practical focus on advocacy techniques, hypothetical case studies, checklists, interviews from the field and lists of furtherresources, this manual equips readers with the knowledge and skills necessary to engage in sophisticated ICC victim advocacy. This book will also appeal to those interested in the workings of International Criminal Law and in victim advocacy and victimology more broadly.

Emerging Applications of Carbon Nanotubes in Drug and Gene Delivery brings together principles behind the formation, characterization and development of carbon nanotubes (CNTs) with recent advances in drug and gene delivery applications. The book begins with an introduction to the unique properties of CNTs, as well as the various synthesis, purification and functionalization methods available. Later chapters cover drug and gene delivery using CNTs for therapeutic applications, comparing advantages and disadvantages of each. The book then goes on to discuss toxicity and safety challenges in using CNTs in biomedicine, with a forward-look at regulatory requirements and clinical translations. This book offers a detailed reference for materials scientists, biomedical engineers, pharmaceutical scientists and geneticists interested in CNTs and nanomedicine. - Provides focused coverage of nanotubes for use in drug and gene delivery applications, offering much-needed detail amongst broader nanomedicine texts - Details the properties, characterization, synthesis, functionalization and applications of CNTs in drug and gene delivery - Discusses toxicity, safety and regulatory aspects of CNTs, with a look towards the clinical translation of CNTs

Professor Kok Khoo Phua is the Founding Director and Emeritus Professor of the Institute of Advanced Studies (IAS) at Nanyang Technological University (NTU) and Adjunct Professor of Department of Physics both at Nanyang Technological University (NTU) and National University of Singapore (NUS). He is the Chairman and Editor-in-Chief of World Scientific Publishing Co Pte Ltd.When he was elected a Fellow of the American Physical Society (APS) in 2009, the citation read:'For tireless efforts to strengthen scientific research throughout Asia and promote international physics education and scholarly exchanges, and for enriching science and education through the World Scientific Publishing Company he founded.'This unique volume on the occasion of his 80th birthday is a compilation of tributes from his friends who have known him for decades along with scientific articles that celebrate his visionary approach to promote science worldwide.

Stimuli-Responsive Nanocarriers: Recent Advances in Tailor-Made Therapeutics compiles dispersed knowledge into a complete and comprehensive source to help researchers understand and progress stimuli-responsive nanocarriers. The book contains recent advancements made in the field of stimuli-responsive nanocarriers with their application in controlled drug delivery against various diseases. It focuses on the design, mechanism, construction, therapeutic application and future challenges of stimuli-responsive nanocarriers which will help new researchers in designing next generation tailor-made advanced therapeutics. Finally, the book covers future aspects and challenges present in the route of development of stimuli responsive nanocarriers for disease therapeutics. Various recent advances and biomedical applications assembled in this book will guide scientists on how to design and develop novel controlled drug release systems. - Provides comprehensive knowledge of basic design, mechanism and construction of nanocarrier based stimuli-responsive drug releases - Explores various nanocarriers characteristically used in the development of stimuli-responsive drug release systems - Envisages future opportunities, challenges and implementation of nanocarrier based stimuli-responsive drug release systems in disease therapeutics

This book describes many novel approaches of microbial bioremediation including conventional and modern approaches, metagenomics, biosurfactants and nano-based bioremediation. Also presents up-to-date knowledge about biodegradation of solid and liquid contaminants in the rhizospheric zone by plant (rhizo)-microbiome interface. It also illustrates communication pathways based on evolving methodologies, bioinformatic tools which provides insights into the functional dynamics of bioremediation process by the host-microbiome interface. The different chapters explain the mechanism and outcomes during the process of bioremediation. The book broadly depicts the following: Advances in bioremediation through nanoremediation, rhizo-remediation, bioremediation of different ecosystems like polluted waters, industrial effluents, bioremediation of metal and organic pollutants, toxic dyes etc. The book is very useful for researchers and students in the fields of applied and environmental microbiology. It is also meant for industry experts and professionals working in the field of bioremediation and waste management.

Nuclear and Radiochemistry The leading resource for anyone looking for an accessible and authoritative introduction to nuclear and radiochemistry In the newly revised Fourth Edition of Nuclear and Radiochemistry: Fundamentals and Applications, distinguished chemist Jens-Volker Kratz delivers a two-volume handbook that has become the gold standard in teaching and learning nuclear and radiochemistry. The books cover the theory and fundamentals of the subject before moving on the technical side of nuclear chemistry, with coverage of nuclear energy, nuclear reactors, and radionuclides in the life sciences. This latest edition discusses the details and impact of the Chernobyl and Fukushima nuclear disasters, as well as new research facilities, including FAIR and HIM. It also incorporates new methods for target preparation and new processes for nuclear fuel recycling, like EURO-GANEX. Finally, the volumes extensively cover environmental technological advances and the effects of radioactivity on the environment. Readers will also find: An accessible and thorough introduction to the fundamental concepts of nuclear physics and chemistry, including atomic processes, classical mechanics, relativistic mechanics, and the Heisenberg Uncertainty Principle Comprehensive explorations of radioactivity in nature, radioelements, radioisotopes and their atomic masses, and other physical properties of nuclei Practical discussions of the nuclear force, nuclear structure, decay modes, radioactive decay kinetics, and nuclear radiation In-depth examinations of the statistical considerations relevant to radioactivity measurements Written for practicing nuclear chemists and atomic physicists, Nuclear and Radiochemistry: Fundamentals and Applications is also an indispensable resource for nuclear physicians, power engineers, and professionals working in the nuclear industry.

This book covers various aspects of thermal energy storage. It looks at storage methods for thermal energy and reviews the various materials that store thermal energy and goes on to propose advanced materials that store energy better than conventional materials. The book also presents various thermophysical properties of advanced materials and the role of thermal energy storage in different applications such as buildings, solar energy, seawater desalination and cooling devices. The advanced energy storage materials have massive impact on heat transfer as compared to conventional energy storage materials. A concise discussion regarding current status, leading groups, journals and the countries working on advanced energy storage materials has also been provided. This book is useful to researchers, professionals and policymakers alike.

The growing need for a concise and comprehensive overview of the world of interest groups, lobbying, and public affairs called for a compendium of existing research, key theories, concepts, and case studies. This project is the first transnational encyclopedia to offer such an interdisciplinary and wide overview of these topics, including perspectives on public relations, crisis management, communication studies, as well as political science, political marketing, and policy studies. It is an interdisciplinary work, which involved an extraordinary pool of contributors made up of leading scholars and practitioners from all around the globe; it is a live and evolving project focused on drawing together grounded international knowledge for our diverse and developing world. The 200+ entries of the Palgrave Encyclopedia of Interest Groups, Lobbying and Public Affairs (to be found as a live reference work online here, and in two print volumes in 2022) address these research avenues, tackling a growing demand for a comprehensive international reference work regarding key global sectors and policymaking structures, looking beyond the traditional markets of Europe and North America to incorporate practice and research from Asia, Africa, Oceania, and Latin America. This encyclopedia acts as a synthesis of existing research, and aims to aid academics, students, and practitioners navigate their relevant fields around the globe.

Statistics is a key characteristic that assists a wide variety of professions including business, government, and factual sciences. Companies need data calculation to make informed decisions that help maintain their relevance. Design of experiments (DOE) is a set of active techniques that provides a more efficient approach for industries to test their processes and form effective conclusions. Experimental design can be implemented into multiple professions, and it is a necessity to promote applicable research on this up-and-coming method. Design of Experiments for Chemical, Pharmaceutical, Food, and Industrial Applications is a pivotal reference source that seeks to increase the use of design of experiments to optimize and improve analytical methods and productive processes in order to use less resources and time. While highlighting topics such as multivariate methods, factorial experiments, and pharmaceutical research, this publication is ideally designed for industrial designers, research scientists, chemical engineers, managers, academicians, and students seeking current research on advanced and multivariate statistics.

This intriguing and accessible book examines the experiments on neutrino oscillations. It argues that this history gives us good reason to believe in the existence of neutrinos, a particle that interacts so weakly with matter that its interaction length is measured in light years of lead. Yet, the scientific process has provided evidence of the elusive neutrino. Written in a style accessible to any reader with a college education in physics, Are There Really Neutrinos? is of interest to students and researchers alike. This second edition contains a new epilogue highlighting the new developments in neutrino physics over the past 20 years.

This book reviews the recent achievements in neutrino physics over the last two decades, ranging from the first experiments on nuclear beta-decay, that have brought to its discovery, up to the newest terrestrial experiments and cosmological measurements. In particular, it provides a summary of the properties of neutrinos in and beyond the Standard Model, it treats of the neutrinos masses, of the double beta-decay, and neutrino oscillations, and at last, it focuses on the study of extraterrestrial neutrinos of different origins: atmospheric, solar, and cosmogenic.

As technology advances, the emergence of 5G has become an essential discussion moving forward as its applications and benefits are expected to enhance many areas of life. The introduction of 5G technology to society will improve communication speed, the efficiency of information transfer, and end-user experience to name only a few of many future improvements. These new opportunities offered by 5G networks will spread across industry, government, business, and personal user experiences leading to widespread innovation and technological advancement. What stands at the very core of 5G becoming an integral part of society is the very fact that it is expected to enrich society in a multifaceted way, enhancing connectivity and efficiency in just about every sector including healthcare, agriculture, business, and more. Therefore, it has been a critical topic of research to explore the implications of this technology, how it functions, what industries it will impact, and the challenges and solutions of its implementation into modern society. Research Anthology on Developing and Optimizing 5G Networks and the Impact on Society is a critical reference source that analyzes the use of 5G technology from the standpoint of its design and technological development to its applications in a multitude of industries. This overall view of the aspects of 5G networks creates a comprehensive book for all stages of the implementation of 5G, from early conception to application in various sectors. Topics highlighted include smart cities, wireless and mobile networks, radio access technology, internet of things, and more. This all-encompassing book is ideal for network experts, IT specialists, technologists, academicians, researchers, and students.

Private Interessenorganisationen sind auf staatliche Veranlassung hin bisweilen so eng mit den Staatsfunktionen der Gesetzgebung, Vollziehung und Rechtsprechung verflochten, daß die privat organisierten Interessen bzw. deren Vertreter die Ausübung dieser staatlichen Funktionen (mit-)steuern. Hans-Georg Dederer untersucht u.a. das zentrale Problem, das sich dabei stellt: die demokratische Legitimation dieser'korporativen Staatsgewalt'. Als das normativ effektivste Legitimations- und Steuerungsinstrument vermag das Parlamentsgesetz neben funktioneller, organisatorischer, prozeduraler und inhaltlicher Legitimation insbesondere auch personelle Legitimation zu vermitteln. Um ein hinreichendes Legitimationsniveau zu erreichen, bedürfen konkrete Formen korporativer Staatsgewalt regelmäßig parlamentsgesetzlicher Steuerung dessen, was im Lichte des Demokratie- und des Rechtsstaatsprinzips in Bezug auf die jeweilige konkrete Form korporativer Staatsgewalt'wesentlich'ist. Wesentlich sind beispielsweise die Sicherung hinreichender Interessenpluralität, die tendenziell vollständige Auswahl der zu repräsentierenden Interessen und der für diese Interessen repräsentativen privaten Interessenorganisationen oder die Merkmale für Eignung und Befähigung der Interessenvertreter.

Alles, was für die Therapie psychischer Erkrankungen wichtig ist! Durch die jährliche Aktualisierung ist gewährleistet, dass auch neueste Forschungsergebnisse enthalten sind. Sie erhalten die aktuellen evidenzbasierten Therapieempfehlungen zu den häufigsten psychischen Erkrankungen, basierend auf den erfolgreichen STATE OF THE ART-Symposien des Kongresses der Deutschen Gesellschaft für Psychiatrie und Psychotherapie, Psychosomatik und Nervenheilkunde (DGPPN), der 2020 als digitaler Kongress stattfindet. Alle Inhalte orientieren sich an den nationalen und internationalen Leitlinien. Neu in der 16. Auflage: Alle Abbildungen und Kästen jetzt farbig Neue Kapitel „Psychische Erkrankungen und Schwangerschaft'und „Notfälle in der Psychiatrie'Aufnahme der „Leitlinien unter Federführung der DGPPN'

The abundance of organic pollutants found in wastewater affect urban surface waters. Traditional wastewater management technologies focus on the removal of suspended solids, nutrients and bacteria, however, new pollutants such as synthetic or naturally occurring chemicals are often not monitored in the environment despite having the potential to enter the environment and cause adverse ecological and human health effects. Collectively referred to as'emerging contaminants,'they are mostly derived from domestic activities and occur in trace concentrations ranging from pico to micrograms per liter. Environmental contaminants are resistant to conventional wastewater treatment processes and most of them remain unaffected, causing contamination of receiving water. This in turn leads to the need for advanced wastewater treatment processes capable of removing environmental contaminants to ensure safe fresh water sources. This book provides an up-to-date overview of the current bioremediation strategies, including their limitations, challenges and their potential application to remove environmental pollutants. It also introduces the latest trends and advances in environmental bioremediation, and presents the state-of-the-art in biological and chemical wastewater treatment processes. As such, it will appeal to researchers and policy-makers, as well as undergraduate and graduate environmental sciences students.

This book illustrates the currently available strategies for managing phytonematodes. It discusses the latest findings on plant-pathogen-microbiome interactions and their impacts on ecosystems, and provides extensive information on the application of microorganisms in the sustainable management of phytonematodes. This is followed by an in-depth discussion of the application of potential strains of biocontrol fungi, endophytes and actinomycetes to enhance plants'ability to fend off phytonematode attacks, leading to improved plant health. In conclusion, the book addresses new aspects like the biofabrication of nanoparticles and their application in plant disease management, and presents an extensive list for further reading.

Zu den Erstaunlichkeiten der DDR gehörte der Umstand, dass es neben dem'einheitlichen sozialistischen Bildungssystem'ein vielfältiges konfessionell bzw. kirchlich gebundenes Bildungswesen gab. Dieses reichte von Kindergärten, Schulen und Konvikten über Vorseminare, Berufsausbildungen, Fort- und Weiterbildungen oder kirchliche Hochschulen bis zu Bildungshäusern, Evangelischen Akademien, Filmdiensten, Kunstdiensten und einem ausdifferenzierten Mediensystem. Es bestand überwiegend aus Einrichtungen in Trägerschaft von Kirchen oder Religionsgemeinschaften, im Einzelfall, etwa den Theologie-Sektionen an den Universitäten, aber auch aus staatlich getragenen Institutionen. Die Anzahl der beteiligten Institutionen und Bildungsformen summiert sich auf rund 1.000. Mit dem hier vorliegenden Handbuch wird eine Lücke in der Dokumentation der DDR-Bildungsgeschichte geschlossen. [Parallel World. Compendium of the Confessional Bound Education System of the GDR] Astonishingly, the GDR had, in addition to the'unified socialist education system', a diverse confessional or ecclesiastically bound education system. This ranged from kindergartens, schools and halls of residence to pre-seminars, vocational training, postgraduate training and further education or theological seminary to educational institutions, Evangelical academies, film services, art services and a differentiated media system. It consisted mainly of institutions sponsored by churches or religious communities, though in individual cases, such as the theology sections at the universities, also of government-supported institutions. The number of participating institutions and forms of education adds up to around 1,000.

Advanced Lightweight Multifunctional Materials presents the current state-of-the-art on multifunctional materials research, focusing on different morphologies and their preparation and applications. The book emphasizes recent advances on these types of materials as well as their application. Chapters cover porous multifunctional materials, thermochromic and thermoelectric materials, shape memory materials, piezoelectric multifunctional materials, electrochromic and electrorheological, soft materials, magnetic and photochromic materials, and more. The book will be a valuable reference resource for academic researchers and industrial engineers working in the design and manufacture of multifunctional materials, composites and nanocomposites. - Provides detailed information on design, modeling and structural applications - Focuses on characteristics, processing, design and applications - Discusses the main types of lightweight multifunctional materials and processing techniques, as well as the physico-chemical insights that can lead to improved performance

Recent Advancement in ProdrugsDrugs used as medicines have many limitations like low chemical stability, aqueous solubility, or oral absorption/bioavailability, rapid presystemic metabolism, toxicity, inadequate site specificity, or poor patient acceptance/compliance (unwanted adverse effects, unacceptable taste or odor, irritation or pain). Prodrugs design is an approach to overcome these limitations.Key features Covers recent advancements in development of prodrugs Presents balanced synthesis and applications of prodrug chemistry Discusses broad spectrum of prodrug categories and outlines industrial applications Reviews prodrugs in cancer nanomedicine, its therapy and treatment Elucidates mathematical models to study the kinetics of prodrugs This book covers recent advances in the design of prodrugs. It contains all the significant recent examples of prodrug chemistry developments and will aid academics and researchers seeking to generate new projects in the field.

London dispersion interactions are responsible for numerous phenomena in physics, chemistry and biology. Recent years have seen the development of new, physically well-founded models, and dispersion-corrected density functional theory (DFT) is now a hot topic of research. This book is an overview of current understanding of the physical origin and modelling of London dispersion forces manifested at an atomic level. It covers a wide range of system, from small intermolecular complexes, to organic molecules and crystalline solids, through to biological macromolecules and nanostructures. In presenting a broad overview of the of the physical foundations of dispersion forces, the book provides theoretical, physical and synthetic chemists, as well as solid-state physicists, with a systematic understanding of the origins and consequences of these ubiquitous interactions. The presentation is designed to be accessible to anyone with intermediate undergraduate mathematics, physics and chemistry.

This book constitutes the proceedings of the Second International Conference on Information and Communication Technology for Development for Africa, ICT4DA 2019, held in Bahir Dar, Ethiopia, in May 2019.The 29 revised full papers presented were carefully reviewed and selected from 69 submissions. The papers address the impact of ICT in fostering economic development in Africa. In detail they cover the following topics: artificial intelligence and data science; wireless and mobile computing; and Natural Language Processing.

The Nature of Nordic Music explores two distinctive yet complementary understandings of the term ‘nature': the inherent features, characters and qualities of contemporary Nordic music, and how the elemental forces of nature, the phenomena of the physical world (landscape, climate, environment), inspire and condition creativity here.Within a broader debate about the meaning of ‘Nordicness', 12 case studies challenge our assumptions about a ‘Nordic tone'to reveal a creative energy that is diverse and cosmopolitan in outlook. Each of the three parts of the book – ‘Identities', ‘Images'and ‘Environments'– accommodates an eclectic array of musical genres (classical, popular, jazz, folk, electronic).This book will appeal to anyone interested in Nordic music and culture, especially students and researchers.

Legal skills are an important and increasing part of undergraduate law degrees as well as postgraduate vocational law courses. This fully updated fourth edition continues to bring together the theory and practice of these skills in an accessible and practical context. The authors draw on their experience of teaching and of law in practice to develop the core skills taught on both undergraduate and postgraduate courses. Skills covered include: • written communication; • mediation; • opinion writing; • drafting; • advocacy; • interviewing; • negotiation; • legal research. The text also considers the professional and ethical context of legal practice, provides an insight into the legal services landscape as well as offering valuable careers advice. Diagrams and flow charts help to explain and develop each skill and each chapter ends with suggestions for further reading. A Practical Guide to Lawyering Skills is essential reading for all undergraduate and vocational law students seeking to develop the necessary skills to work successfully with law in the twenty-first century.

The proliferation of wireless communications has led to mobile computing, a new era in data communication and processing allowing people to access information anywhere and anytime using lightweight computer devices. Aligned with this phenomenon, a vast number of mobile solutions, systems, and applications have been continuously developed. However, despite the opportunities, there exist constraints, challenges, and complexities in realizing the full potential of mobile computing, requiring research and experimentation. Algorithms, Methods, and Applications in Mobile Computing and Communications is a critical scholarly publication that examines the various aspects of mobile computing and communications from engineering, business, and organizational perspectives. The book details current research involving mobility challenges that hinder service applicability, mobile money transfer services and anomaly detection, and mobile fog environments. As a resource rich in information about mobile devices, wireless broadcast databases, and machine communications, it is an ideal source for computer scientists, IT specialists, service providers, information technology professionals, academicians, and researchers interested in the field of mobile computing.

This book describes the principles and practice of critical care toxicology. Critical care toxicology is a field of medicine dedicated to the evaluation and treatment of poisoned and envenomated patients. This book will highlight the nuances of clinical toxicology with in-depth and most recent management of poisoning. This book comprised of 10 sections, which include general management of poisoning or overdose, drugs of abuse, CNS toxins, pulmonary toxins, cardiac toxins, gastrointestinal and liver toxins, hematological toxins, renal toxins and extracorporeal therapies, pesticides and rodenticides, and miscellaneous toxicities, which are further divided into 44 chapters. The book includes poisoning management ranging from common household poisons to drug overdose, industrial, agricultural, chemical warfare and nerve agent poisonings, from ABC of poisoning to extracorporeal and emerging treatment modalities (LET). The material is presented in a format, which is easy to read and digest. This book will be a useful resource for clinicians, leading to improved outcomes of critically-ill poisoned patients.

This book considers how largely accepted ‘legal truths'about drugs and addiction are made and sustained through practices of lawyering.Lawyers play a vital and largely underappreciated role in constituting legal certainties about substances and ‘addiction', including links between alcohol and other drugs, and phenomena such as family violence. Such practices exacerbate, sustain and stabilise ‘addicted'realities, with a range of implications – many of them seemingly unjust – for people who use alcohol and other drugs. This book explores these issues, drawing upon data collected for a major international study on alcohol and other drugs in the law, including interviews with lawyers, magistrates and judges; analyses of case law; and legislation. Focussing on an array of legal practices, including processes of law-making, human rights deliberations, advocacy and negotiation strategies, and the sentencing of offenders, and buttressed by overarching analyses of the ethics and politics of such practices, the book looks at how alcohol and other drug ‘addiction'emerges and is concretised through the everyday work lawyers and decision makers do. Foregrounding ‘practices', the book also shows that law is more fragile than we might assume. It concludes by presenting a blueprint for how lawyers can rethink their advocacy practices in light of this fragility and the opportunities it presents for remaking law and the subjects and objects shaped by it.This ground-breaking book will be of interest not only to those studying and working within the field of alcohol and drug addiction but also to lawyers and judges practising in this area and to scholars in a range of disciplines, including law, science and technology studies, sociology, gender studies and cultural studies

Rice Chemistry and Technology, Fourth Edition, is a new, fully revised update on the very popular previous edition published by the AACC International Press. The book covers rice growth, development, breeding, grain structure, phylogenetics, rice starch, proteins and lipids. Additional sections cover rice as a food product, health aspects, and quality analysis from a cooking and sensory science perspective. Final chapters discuss advances in the technology of rice, with extensive coverage of post-harvest technology, biotechnology and genomic research for rice grain quality. With a new, internationally recognized editor, this new edition will be of interest to academics researching all aspects of rice, from breeding, to usage. The book is essential reading for those tasked with the development of new products. - Identifies the nutrition and health benefits of rice - Covers the growing and harvesting of rice crops - Includes the use of rice and byproducts beyond food staple - Explains rice chemistries, including sections on starch, protein and lipids - Contains contributions from a world leading editorial team who bring together experts from across the field - Contains six new chapters focusing on rice quality

Stimuli Responsive Polymeric Nanocarriers for Drug Delivery Applications: Volume Two: Advanced Nanocarriers for Therapeutics discusses, in detail, the recent trends in designing dual and multi-responsive polymers and nanoparticles for safe drug delivery. Chapters cover dual-responsive polymeric nanocarriers for drug delivery and their different stimuli, multi-responsive polymeric nanocarriers, and the therapeutic applications of stimuli-responsive polymers. With an emphasis on advanced medical applications and synergistic operational and technological methodologies for the improvement of polymers systems for the production of stimuli-responsive polymers, this book is essential reading for materials scientists and researchers working in the drug delivery and pharmaceutical industries. As innovation and development in the area of stimuli responsive polymer-based nanomaterials for drug delivery is moving fast and there is an increased global demand for biodegradable and biocompatible responsive polymers and nanoparticles for safe drug delivery, users will find this to be a timely resource. - Focusses on the most advanced technologies, recent evaluation methods, technical aspects, and advanced synthesis techniques stimuli-responsive polymers - Examines advanced medical applications of stimuli responsive polymers - Analyzes synergistic operational and technological methodologies for the improvement of polymer systems for the production of stimuli-responsive polymers in drug delivery

Fibrinolysis in Disease reviews the state of the art of basic and clinical aspects of the fibrinolytic enzyme system. The text, authored by outstanding and internationally known investigators, is presented in two books.The Malignant Process, Interventions in Thrombogenic Mechanisms, and Novel Treatment Modalities discusses the molecular biology of the system's key components and their fundamental roles in a variety of thrombotic and metabolic disorders. Molecular and Hemovascular Aspects of Fybrinolysis presents the latest findings and concepts of the association between plasminogen activator (u-PA) overexpression and abnormal growth regulation in a variety of solid tumors and in leukemia. One chapter deals with various successful interventions in thrombogenic mechanisms, ranging from exercise and diet to anticoagulants and direct and indirect thrombolytic agents. It concludes with a projection of exciting, novel treatment modalities in thrombotic and malignant diseases.

يعد الأداء الاستراتيجي دالة الأنشطة للشركة وانه المرآة التي تعكس وضعها من الجوانب المختلفة فضلا'عن انه عبارة عن نتائج المخرجات التي يتم الحصول عليها من المدخلات والعمليات ويعبر عن قدرة الشركة على تحقيق أهدافها في الأمد الطويل. اذ قد يتأثر بالعديد من المتغيرات ومنها: التزامات الشراء وفقا'لـSeven Rights)) والتي تتضمن الشراء بالجودة الصحيحة, الشراء بالكمية الصحيحة, الشراء بالوقت الصحيح, الشراء بالسعر الصحيح, الشراء بالمكان الصحيح, الشراء بالمعلومات الصحيحة, الشراء من المورد الصحيح.

First published in 1994, Role of Procoagulant Activity in Health and Disease discusses different aspects of the pathobiology and consequences of the induction of cellular procoagulants. The first part of the book addresses the molecular and cellular biology of procoagulant activity induction (PCA). This includes the recent data on cellular pathways of induction of PCA and the molecular nature of the different procoagulants identified to date. The book addresses interactions between macrophages and endothelial cells, focusing on those aspects most relevant to induction of procoagulant activities, including the role of adhesion molecules. The second portion of the book describes the relevance of PCA to a number of human and experimental diseases, including infectious diseases, gastrointestinal diseases, liver disease, renal disease, neoplastic diseases, allograft rejection, and pulmonary disease. This book will not only be of value to the basic scientist, but also to pathologists and clinicians, and to others wishing to understand the role of immunologically mediated induction of cellular coagulants and their relevance to disease.

The only combined organic photochemistry and photobiology handbookAs spectroscopic, synthetic and biological tools become more and more sophisticated, photochemistry and photobiology are merging-making interdisciplinary research essential. Following in the footsteps of its bestselling predecessors, the CRC Handbook of Organic Photochemistry and Pho

Lactobacillus is a highly phylogenetically and metabolically diverse genus comprising more than 200 species. As food-grade microorganisms, lactobacilli have long been exploited in the feed, food and beverage industries, with applications ranging from extending the shelf-life of food products to their use as probiotics with health-promoting properties. In addition lactobacilli are also important producers of industrial chemicals such as lactic acid and gamma-aminobutyric acid. The considerable commercial importance has stimulated a plethora of research projects studying the genomics, molecular biology and metabolic engineering of these bacteria and prompted the need for this concise book which provides a timely overview of the field. Topics covered include: the genomic perspective on niche adaptability; catabolic pathways of complex carbohydrates metabolism; the production of lactate; genetics, biology of the cell envelope and applications of the S-layer proteins; lactobacilli bacteriophage; DNA transfer into Lactobacillus species; recombinant gene expression and genomics of antibiotic resistance in Lactobacillus. This book is an invaluable source of information and essential reading for everyone working with lactobacilli, lactic acid bacteria and probiotics, from the PhD student to the experienced scientist, in academia, the pharmaceutical or biotechnology industries and those working in clinical environments.

The book presents the proceedings of the 2nd International Conference on 5G for Ubiquitous Connectivity (5GU 2018), which took place on December 4-5, 2018 in Nanjing, People's Republic of China. The aim of this conference is to bring together researchers and developers as well as regulators and policy makers to present their latest views on 5G, including new networking, new wireless communications, resource control & management, future access techniques, new emerging applications, and latest findings in key research activities on 5G. The book is applicable to researchers, academics, students, and professionals.Features practical, tested applications in 5G for ubiquitous connectivity;Includes discussion of 5G for ubiquitous connectivity in relation to wireless communications, resource control & management, and future access techniques;Applicable to researchers, academics, students, and professionals.

Tunneling reactions in chemistry are characterized by the low-temperature limit when the classical contribution is negligible. Many practical applications benefit from the lack of heat and have a deep physical basis. Interesting advantages of chemical synthesis at low temperatures have also been demonstrated. This book covers fundamental and practical aspects of the processes and experimental and theoretical methods used in the field. The chapters are written by leading scientists who have very strong experience in the selected topics, and many practical recommendations can be found in this book.