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This book takes up theoretical and practical discussions of children and young people's participation in public decision-making by taking into account existing literature from throughout childhood studies, sociology of childhood, children's human rights studies, decolonization studies, and intersectionality studies. Through case studies conducted in Brazil, Bangladesh, Sierra Leone, and Ghana, Cuevas-Parra provides extensive empirical data from beyond the Global North and confronts dominant views of power, inequalities, and agency. The understanding that children and young people are immersed in intersectional social structures, where they are never'simply children'but individuals with multiple specific identities, cuts across the book.

The World Stroke Organization reports that “stroke has already reached epidemic proportions. Globally1 in 4 adults over the age of 25 will have a stroke in their lifetime. 12.2 million people worldwide will have their first stroke this year, and 6.5 million will die as a result.” Ischemic strokes are the most common type of stroke, with about 87% of all strokes being ischemic strokes.This new volume addresses this epidemic by presenting detailed studies on ischemic injury, with emphasis on the molecular-level mechanisms and the role of signaling pathways in the body, their structure, and their mechanism of action. The book focuses on molecular pharmacology plans and explains the new areas of research on the discovery of therapeutic molecules that can be used for combating this life-threatening disease. The authors discuss stroke occurrence at different stages of life as well as sex-based differences in its treatment. They cover aspects of the clinical treatment and diagnosis of patients with cardiovascular events, including in-depth information on the prevention, evaluation, therapy selection, result projection, and long-term course of the disease in affected patients. They also detail the involvement of platelets, neurotransmitters, renin-angiotensin-aldosterone system, and vitamin D in ischemic injury.

Sur le sentier de la recherche, des pierres attirent l'attention. Ce peut être un document inédit qu'on découvre, telle la Déclaration d'indépendance du Bas-Canada de 1838 dont on a beaucoup parlé sans en connaître le fin mot.Ce peut être l'angle un moment mort d'un sujet familier, la croyance de Papineau, ses positions sur la religion, le libre examen et la tolérance.Ce peut être un sujet tabou, par exemple les causes de l'inachèvement du projet d'émancipation coloniale de 1837 et de 1838. Ou oser poser la question de savoir où logeait vraiment l'abbé Lionel Groulx en matière de nationalisme, d'autonomie et d'indépendance.Puis, il y a des trames qui n'apparaissent qu'avec la décantation du temps et qui traversent l'histoire sans qu'on veuille les regarder en face. Un exemple : le fait que depuis 1840 on se soit rabattu sur un nationalisme culturel, faute de mener à terme un nationalisme politique et indépendantiste.Écrits au cours de la dernière décennie, les dix-neuf textes qui composent ce recueil se présentent comme une invitation à retourner des pierres, comme le dit l'auteur.Cet appel à l'exploration du connu et de l'inédit est l'occasion pour le grand spécialiste de l'histoire des idées au Québec de revenir sur des sujets et des figures dont il a déjà traité au cours de sa carrière et de sortir de l'oubli d'autres méconnus.

This handbook presents a comprehensive overview of insect conservation and provides practical solutions to counteract insect declines, at a time where insects are facing serious threats across the world from habitat destruction to invasive species and climate change.The Routledge Handbook of Insect Conservation consist of six sections, covering all aspects of insect conservation, containing contributions from academics, researchers and practitioners from across the globe. Section I addresses the fundamentals of insect conservation and outlines the reason why insects are important and discusses the greatest drivers of insect decline. The chapters in Section II examine the approaches that can be used for insect conservation globally, such as protected areas and agroecology, while highlighting the importance of insects in the composition and function of ecosystems. The chapters in Section III focus on insect populations in the major biomes around the world, from temperate and tropical forests to savannas and grasslands, with the chapters in Section IV focusing on natural and manmade ecosystems of the world, including mountain, soil, urban, island and agricultural habitats. They discuss the unique pressures and challenges for each biome and ecosystem and offer practical solutions for conserving their insect populations. Section V focuses on the assessment and monitoring of insects for conservation, discussing how we can implement practical monitoring protocols and what options are available. A wide variety of methods and tools are examined, including citizen science, bioindication, the role of taxonomy, drones and eDNA. The book concludes by examining policy and education strategies for insect conservation in Section VI. The chapters discuss key issues around social and policy strategies and conservation legislation for ensuring the long-term protection of insects.This book is essential reading for students and scholars of biodiversity conservation and entomology as well as professionals and policymakers involved in conservation looking for real-world solutions to the threats facing insects across the globe.

This handbook provides a comprehensive and critical overview of the gamut of contemporary issues around health and healthcare from a political economy perspective. Its contributions present a unique challenge to prevailing economic accounts of health and healthcare, which narrowly focus on individual behaviour and market processes. Instead, the capacity of the human body to reach its full potential and the ability of society to prevent disease and cure illness are demonstrated to be shaped by a broader array of political economic processes. The material conditions in which societies produce, distribute, exchange, consume, and reproduce – and the operation of power relations therein – influence all elements of human health: from food consumption and workplace safety, to inequality, healthcare and housing, and even the biophysical conditions in which humans live.This volume explores these concerns across five sections. First, it introduces and critically engages with a variety of established and cutting-edge theoretical perspectives in political economy to conceptualise health and healthcare – from neoclassical and behavioural economics, to Marxist and feminist approaches. The next two sections extend these insights to evaluate the neoliberalisation of health and healthcare over the past 40 years, highlighting their individualisation and commodification by the capitalist state and powerful corporations. The fourth section examines the diverse manifestation of these dynamics across a range of geographical contexts. The volume concludes with a section devoted to outlining more progressive health and healthcare arrangements, which transcend the limitations of both neoliberalism and capitalism.This volume will be an indispensable reference work for students and scholars of political economy, health policy and politics, health economics, health geography, the sociology of health, and other health-related disciplines.Chapters 1 & 8 of this book is freely available as a downloadable Open Access PDF at http://www.taylorfrancis.com under a Creative Commons [CC BY NC ND] 4.0 license.

This book is a machine-generated literature overview that explores the impact of the World Trade Organization (WTO) on international trade and its development. It looks at international trade before and after 1995 when WTO was established. It highlights the journey of the reciprocity-based reforms under WTO that were expected to help the developing and less developed countries (LDCs) more vis-à-vis their developed counterparts, given the existence of systemic and structural bottlenecks in the latter territories. The enabling steps were further expected to promote exports from developing countries and LDCs in line with their comparative advantage patterns, enhance the wage level and in turn, facilitate development of local population. The book showcases how during the first decade after WTO inception, a considerable progress was made for facilitating exports from the lower and lower-middle income countries through crucial provisions like less than full reciprocity (LTFR), Generalized System of Preferences (GSP), support measures under Aid for Trade, zero duty preferences under Special and Differential Treatment (SDT) and so on. However, the pace of WTO reforms has slowed down in the aftermath of the sub-prime crisis in 2008-09 and subsequent focus on formation of regional trade agreements (RTAs). In particular, in the aftermath of Covid-19, a trend towards de-globalization has been noticed, with considerable ramifications for the development of lower-income countries. In this background, there is a need to analyze how the deepening of trade flows and the subsequent de-globalization waves in the global canvas have traversed different paths in different continents and draw the appropriate lessons for the understanding the trade-development interlinkage therein. With insightful observations from the human editors, this machine-generated overview would be of interest to academicians, policy research community, advisory research community, and students ofinternational trade globally.^

The first text to take a systems engineering approach to artificial intelligence (AI), from architecture principles to the development and deployment of AI capabilities.Most books on artificial intelligence (AI) focus on a single functional building block, such as machine learning or human-machine teaming. Artificial Intelligence takes a more holistic approach, addressing AI from the view of systems engineering. The book centers on the people-process-technology triad that is critical to successful development of AI products and services. Development starts with an AI design, based on the AI system architecture, and culminates with successful deployment of the AI capabilities. Directed toward AI developers and operational users, this accessibly written volume of the MIT Lincoln Laboratory Series can also serve as a text for undergraduate seniors and graduate-level students and as a reference book. Key features:In-depth look at modern computing technologies Systems engineering description and means to successfully undertake an AI product or service development through deploymentExisting methods for applying machine learning operations (MLOps)AI system architecture including a description of each of the AI pipeline building blocksChallenges and approaches to attend to responsible AI in practice Tools to develop a strategic roadmap and techniques to foster an innovative team environment Multiple use cases that stem from the authors'MIT classes, as well as from AI practitioners, AI project managers, early-career AI team leaders, technical executives, and entrepreneurs Exercises and Jupyter notebook examples

This handbook presents the key topics in the area of computer architecture covering from the basic to the most advanced topics, including software and hardware design methodologies. It will provide readers with the most comprehensive updated reference information covering applications in single core processors, multicore processors, application-specific processors, reconfigurable architectures, emerging computing architectures, processor design and programming flows, test and verification. This information benefits the readers as a full and quick technical reference with a high-level review of computer architecture technology, detailed technical descriptions and the latest practical applications.

The multi-volume set of LNCS books with volume numbers 15059 up to 15147 constitutes the refereed proceedings of the 18th European Conference on Computer Vision, ECCV 2024, held in Milan, Italy, during September 29–October 4, 2024. The 2387 papers presented in these proceedings were carefully reviewed and selected from a total of 8585 submissions. They deal with topics such as computer vision; machine learning; deep neural networks; reinforcement learning; object recognition; image classification; image processing; object detection; semantic segmentation; human pose estimation; 3d reconstruction; stereo vision; computational photography; neural networks; image coding; image reconstruction; motion estimation.

This book is an essential guide for doctors, rheumatologists, orthopedic specialists, and medical researchers. This comprehensive resource demystifies the use of corticosteroid therapy for knee osteoarthritis, providing clear explanations and insights into the latest research. The book explores the effectiveness of corticosteroid treatment, examines the heterogeneity of knee osteoarthritis, and identifies factors that predict treatment response. Utilizing literature reviews, case studies, and statistical analyses, it offers a thorough understanding of this therapeutic approach. Key findings include the mechanisms of corticosteroid action, clinical management strategies, and ethical considerations, supplemented by real-world case studies and patient experiences. This book is a valuable tool for healthcare professionals aiming to improve patient care and advance their understanding of knee osteoarthritis treatment. Enhance your treatment methods and ensure your patients'wellbeing with this indispensable guide.

Wird eine Forderung abgetreten, entsteht eine Vielzahl von rechtlichen Beziehungen zwischen den betroffenen Personen. Was ohnehin schon kompliziert anmutet, wird auf kollisionsrechtlicher Ebene noch komplexer. Die derzeit drängendste Frage ist: Welches Recht wird angewandt, wenn ein Dritter auf eine Forderung zugreifen möchte, die abgetreten wurde? Wie bestimmen wir, ob diese Abtretung ihm gegenüber wirksam ist oder nicht? Hinter diesen Fragen steht ein spannendes Zusammenspiel aus Regelungslücken, EuGH-Rechtsprechung und dem Versuch der Europäischen Kommission, ein Problem zu lösen, bei dem sich die Geister der Mitgliedstaaten scheiden. Theresa Frech zeigt die aktuell bestehende Problematik unter rechtsvergleichenden Gesichtspunkten auf, stellt die diskutierten Lösungsansätze vor und erarbeitet einen eigenen Regelungsvorschlag, welcher den Interessen sämtlicher Beteiligter gerecht wird.

Get to grips with the full stack of edge computing technologies from silicon and cloud to AI, and discover real-world business use cases and applications of edge computing Key FeaturesBenefit from clear, non-technical explanations suitable for entry-level learnersUnderstand the costs, tradeoffs, and technical challenges of building a full-stack edge systemExplore a plethora of different real-world use cases analyzed in detail from a system and business perspectivePurchase of the print or Kindle book includes a free PDF eBookBook DescriptionThe migration of computing to the edge is the logical progression of where computing is performed on a global scale. Edge computing is not a new paradigm but a necessary technology to address issues such as latency, service charges, reliability, connectivity, and privacy. This book walks you through the definition and architecture of edge computing systems and why they are critical in today's ecosystem of IoT devices and an “everything connected” world. You will start your journey with an introduction to different edge computing hardware platforms, which vary by use case. From there, you'll explore operating systems and middleware packages that manage edge devices such as Azure IoT. Then, you will explore communication systems such as near-range Bluetooth and RFID as well as long-range systems such as 5G. Networking protocols will be covered, which are the heart of edge systems. Technologies such as MQTT, which make up the backbone of edge to cloud communication, are examined. Then, you will move on to edge applications such as edge predictive AI and federated computing. We wrap up by investigating the security and vulnerability envelope of edge systems. This book is intended to quickly familiarize you with edge systems technologies and use cases, without burdening you with complicated jargon and low-level details.What you will learnLearn about edge systems'architecture from simple use cases to complex content deliveryLearn the elements of edge hardware and differences in far edge equipmentDevelop a solid understanding of edge communication systems and networkingDevelop an understanding of edge system software and partitioningUnderstand edge services and applications such as AI and federated learningLearn how security comes into play on edge systemsWho this book is forEdge Computing Simplified is for mid-to-senior level technology leaders and managers exploring the realm of IoT and edge computing. Beginners keen to start their journey with IoT and edge computing without diving into technical details will also find this book useful. Some familiarity with IT concepts like networking or cloud computing may help you understand the topics in this book more easily, but the book is written in a way to gently walk you through the complexities of edge technologies.

Psychological Science: The Curious Mind, by award-winning authors and professors Catherine A. Sanderson and Karen Huffman, introduces 21st-century, digital-native students to the fascinating field of psychology. This new program emphasizes the importance of developing scientific literacy and an understanding of research and research methods. The program uses an inviting why-focused framework that taps into students'natural curiosity, incorporating active learning and real-life application to engage students. Psychological Science: The Curious Mind embraces the guidelines released by the American Psychological Association (APA)'s Introductory Psychology Initiative (IPI) in 2021. It provides an excellent framework for instructors who want to implement those guidelines in their Introductory Psychology courses, and it provides students with the content and motivation to achieve the course's ultimate outcome: an enduring, foundational understanding of psychological science.

The first edition of The Struggle for Health was published in 1985 and was widely acclaimed by those seeking a broader and deeper political understanding of ill health, beyond the medical model of care. It was a revolutionary book, charting new ways of understanding and tackling the causes of ill health, and suggesting strategies to enable health for all. This second edition includes health problems that have emerged since the 1980s, notably HIV/AIDs, COVID-19, and other epidemics, and the increase in non-communicable diseases, such as cardiovascular disease and diabetes. It examines some of the health impacts of globalization, specifically on the food and pharmaceutical value chains, and considers the consequences of climate change on the health of populations. However, this edition does not depart from the core message of the original book: Health for All can only be achieved through a more equitable distribution of wealth, resources, and power. The Struggle for Health, Second Edition, utilises the same approach as the first, with a narrative that begins with diseases, then describes historical trends and the limitation of the medical (and commercial) model of care. At each juncture, it asks the question'WHY'- why do people, especially children, still die in large numbers throughout the world, from wholly preventable diseases? Why is it that appropriate provision for health care is not available to every individual in the world? What changes can be made to improve this situation? Most importantly, this edition presents a strengthened call to action, building upon the original work and advocating for systemic changes to ensure justice and equity in health for all.

Social institutions emerge from social practices which coordinate activities by the explicit statement of rules, goals, and values. When artificial social actors are introduced into the physical and symbolic space of institutions, will this affect or transform institutional structures and practices, and how can social robotics as an interdisciplinary endeavor contribute to the ability of our institutions to perform their functions in society? This book presents the proceedings of Robophilosophy 2022, the 5th in the biennial Robophilosophy conference series, held in Helsinki, Finland, from 16 to 19 August 2022. The theme of this edition of the conference was Social Robots in Social Institutions, and it featured international multidisciplinary research from the humanities and social sciences concerning social robotics. The 63 papers, 41 workshop papers and 5 posters included in this book are divided into 4 sections: plenaries, sessions, workshops and posters, with the 41 papers in the ‘Sessions'section grouped into 13 subdivisions including elderly care, healthcare, law, education and art, as well as ethics and religion. These papers explore the anticipated conceptual and practical changes which will come about from the introduction of social robotics into public and private institutions, such as public services, legal systems, social and healthcare services or educational institutions. Offering an exploration of the societal significance of social robots for the future of social institutions, the book will be of interest to both researchers in robotics and to those working in social institutions and enterprises.

Hospitalization, Diagnosis, Treatment, and Surgery: The Lifecycle of Medical Sciences in Iran provides a complete understanding of the lifecycle of medicine in the underserved area of Iran. Coverage will elucidate the importance of communication between scientists in different countries for the further development of research to advance hospitalization infrastructure, diagnosis and treatment of diseases, and surgery techniques and availability. Using a systematic timeline approach, coverage includes early medical sciences to present day of Iran. Each chapter highlights important research, techniques, and procedures throughout the lifecycle of medical sciences and includes topics from bloodletting and setting bones, to anesthesia and vaccines. The content in each chapter emphasizes standard protocols based on international recognition to help developing countries adopt newer technologies. - Covers the lifecycle of medical sciences in Iran for a comprehensive introduction to the developments in hospitalization, diagnosis and treatment of diseases, and surgery - Shows ways that modern technology can be utilized in underserved areas of the world - Provides the unique perspective and insight into the diagnosis and treatment of infectious diseases like M. tuberculosis from a country that has seen the progression of the disease and its available treatments over many years

In this book, Austrian political scientist Arno Tausch, born in 1951, looks back on five decades of political science. Was the current global crisis preventable? Tausch, who has had a long career in academia and administration and is now Visiting Professor of Political Studies and Governance at the University of the Free State, Bloemfontein, South Africa, tries to show in his scholarly memoirs that the unequal relations between centres and peripheries that he has analysed over five decades, as well as the long conflict-ridden cycles of the world economy and world politics, could have been avoided, and Putinism and nationalism and the end of peace and social justice in the West are also linked to the neoliberal model of society in the West, which he learned to reject as a student of Nobel laureate Friedrich August Hayek in Salzburg from 1969 to 1971. He is one of the few political scientists in the world who, since 1991, has persistently warned against the hardening of Russia's course, including in leading Russian academic journals. In 1991 he wrote his book'Russia's Treadmill', the predictions of which have come true in an almost eerie way. But neo-liberal economic policy also corresponds 1:1 with the foreign policy vision of the'neocons', whose policy of NATO expansion first fuelled those destructive forces in Russia like an accelerant, leading to today's world crisis over Ukraine, which could end in a global nuclear catastrophe. The world must leave behind neo-liberalism, and return to political and economic concepts such as those of Michal Kalecki, Kazimierz Laski, Kurt Rothschild and Josef Steindl, whose basic structures he became acquainted with in the 1970s and which are still valid today: demand as the engine of growth, a stable or rising wage share, the growth of the public sector, fiscal coordination, international cooperation, coexistence and the rule of law within the framework of the 1975 Helsinki Accords.

Caroline Sophie Rapatz untersucht die Folgen der Europäisierung des Internationalen Privatrechts (IPR) für das nationale und das staatsvertragliche Kollisionsrecht und für das internationalprivatrechtliche Gesamtsystem. Die Wirkungen der IPR-Verordnungen der EU sind nicht auf ihren Anwendungsbereich begrenzt. Das mitgliedstaatliche Kollisionsrecht wird teils massiv zurückgedrängt, muss aber gleichzeitig zahlreiche Lücken schließen. Der Druck zur Anpassung an europäische Vorstellungen wird durch primärrechtliche Vorgaben noch verstärkt. Die Kollisionsregeln bi- und multilateraler Staatsverträge bleiben von der Europäisierung zwar formell unberührt. Ihr Zusammenspiel mit dem EU-IPR sowie der stetig wachsende Einfluss der EU auf die Interpretation und Weiterentwicklung völkerrechtlicher Rechtsakte lassen jedoch faktische Angleichungszwänge entstehen. Der bisherige Ansatz einer kollisionsrechtlichen Europäisierung durch Einzelrechtsakte ist auf lange Sicht nicht tragfähig und sollte durch ein anderes Modell ersetzt werden.

This book constitutes revised selected papers from the workshops that were affiliated with the 26th International Conference on Financial Cryptography and Data Security, FC 2022, which was held in Grenada during May 2022. FC 2022 presents the following four workshops:CoDecFin 2022: 3rd Workshop on Coordination of Decentralized FinanceDeFi 2022: 2nd Workshop on Decentralized FinanceVoting 2022: 7th Workshop on Advances in Secure Electronic VotingWTSC 2022: 6th Workshop on Trusted Smart Contracts

This book presents the proceedings of the NeuroIS Retreat 2022, June 14-16, Vienna, Austria, reporting on topics at the intersection of information systems (IS) research, neurophysiology and the brain sciences. Readers will discover the latest findings from top scholars in the field of NeuroIS, which offer detailed insights on the neurobiology underlying IS behavior, essential methods and tools and their applications for IS, as well as the application of neuroscience and neurophysiological theories to advance IS theory.

Managing Treatment-Resistant Depression: Road to Novel Therapeutics defines TRD for readers, discussing the clinical and epidemiological predictors, economic burden and neurobiological factors. In addition, staging methods for treatment resistance are fully covered in this book, including serotonin specific reuptake inhibitors, serotonin norepinephrine reuptake inhibitors, other classes of antidepressants, including tricyclic antidepressants and monoamine oxidase inhibitors, augmentation strategies, and newer antidepressant treatments like ketamine and esketamine. In addition, evidence supporting the use of psychotherapies and neuromodulation strategies are also reviewed. Written by top experts in the field, this book is the first of its kind to review all methods of treatment for TRD. - Defines Treatment-Resistant Depression and Staging Treatment Intensity - Includes Treatment-Resistant Depression options for children, adolescents, geriatrics, during pregnancy, and during post-partum and menopause transitions - Discusses the use of Ketamine and Esketamine for treatment-resistant depression

Since the 1970's, microprocessor-based digital platforms have been riding Moore's law, allowing for doubling of density for the same area roughly every two years. However, whereas microprocessor fabrication has focused on increasing instruction execution rate, memory fabrication technologies have focused primarily on an increase in capacity with negligible increase in speed. This divergent trend in performance between the processors and memory has led to a phenomenon referred to as the “Memory Wall.” To overcome the memory wall, designers have resorted to a hierarchy of cache memory levels, which rely on the principal of memory access locality to reduce the observed memory access time and the performance gap between processors and memory. Unfortunately, important workload classes exhibit adverse memory access patterns that baffle the simple policies built into modern cache hierarchies to move instructions and data across cache levels. As such, processors often spend much time idling upon a demand fetch of memory blocks that miss in higher cache levels. Prefetching—predicting future memory accesses and issuing requests for the corresponding memory blocks in advance of explicit accesses—is an effective approach to hide memory access latency. There have been a myriad of proposed prefetching techniques, and nearly every modern processor includes some hardware prefetching mechanisms targeting simple and regular memory access patterns. This primer offers an overview of the various classes of hardware prefetchers for instructions and data proposed in the research literature, and presents examples of techniques incorporated into modern microprocessors.

The knee meniscus was once thought to be a vestigial tissue, but is now known to be instrumental in imparting stability, shock absorption, load transmission, and stress distribution within the knee joint. Unfortunately, most damage to the meniscus cannot be effectively healed by the body. Meniscus tissue engineering offers a possible solution to this problem by striving to create replacement tissue that may be implanted into a defect site. With a strong focus on structure-function relationships, this book details the essential anatomical, biochemical, and mechanical aspects of this versatile tissue and reviews current meniscus tissue engineering strategies and repair techniques. We have written this text such that undergraduate students, graduate students, and researchers will find it useful as a first foray into tissue engineering, a cohesive study of the meniscus, or a reference for meniscus engineering specifications. Table of Contents: Structure-Function Relationships of the Knee Meniscus / Pathophysiology and the Need for Tissue Engineering / Tissue Engineering of the Knee Meniscus / Current Therapies and Future Directions

Há anos recebemos noticiários dos elevados índices de suicídio na cidade de Marília e região. Para elucidar tal fenômeno, foi necessário a implementação de aprofundada pesquisa epidemiológica. São surpreendentes os achados! De fato, a questão suicida faz parte do interesse de todo cidadão, desde o professor do ensino primário, ao juiz, prefeito, governador, médicos, pais etc. Todos precisamos saber o que acontece na mente suicida. Os resultados deste estudo foram descritos de maneira bastante técnica, entretanto sua linguagem é acessível a qualquer leitor que se mantenha atento ao repertório introdutório e o siga na teorização e discussão. Se bem aproveitadas, as informações de Marília podem servir de esclarecimento para qualquer outra cidade, pois são sempre seres humanos aqueles que sofrem o mal suicida. Prepare-se para conhecer Morbosus excludens, o agente patogênico do suicídio, e saber como evitá-lo. Leitura fundamental para qualquer cidadão deste mundo.

Substance misuse and addictions are a public health issue. They affect the well-being of each community and nation as a whole. It is, therefore, necessary to identify, educate, and treat individuals who are addicted to substances. Policies and procedures go hand-in-hand with public health education and safety. The science behind the public health issues of one drug may be applicable to other drugs as well. However, marshalling all of the aforementioned information into a single source is somewhat difficult due to the wide array of material. The Editors address this by compiling the research in this single reference work that serves as a'one-stop-shopping'approach to everything readers need to know about the scientific basis of public health and addictions and agents of misuse.Apart from active agents that have a plant or chemical basis, there is a need to consider that there are other forms of addiction which may havecommon modes of causality or prevention. These include food addiction, gaming, gambling, and other non-drug addictions. These types of addiction may be related to the addiction of drugs.The Handbook of Substance Misuse and Addictions: From Biology to Public Health offers a holistic understanding of the relationship between public health and substance misuse. The text provides a common platform upon which other forms of addiction or substance misuse can be understood and treated. Addiction processes involve understanding the biological processes as well as behavior, psychology, sociology, and public health, all of which are interlinked. This Handbook is a useful reference for lecturers, students, researchers, practitioners, and other professionals in public health, addiction science, epidemiology, health education, health promotion, and health sciences.

Nanoscience and nanotechnology, the application of the research-based nanoscale science, have changed significantly over the last three and a half decades. The “bucky” ball, 60 carbon atoms arranged like a soccer ball, and an often-used symbol of nanotechnology, was discovered in 1985 and 4 years later scientists at IBM were able to manipulate xenon atoms on a surface. In the intervening years, nanotechnology has evolved from a singly focused research topic to an understanding that infiltrates every aspect of science and engineering disciplines. In addition, nanotechnology, and both naturally occurring and engineered nanomaterials, have become the focus of legal, environmental, and application and regulation disciplines. The first portion of this text serves as an introduction to nanotechnology: the history, mathematical concepts, and instruments required to study and manipulate the world at the atomic scale. The later portion of the text discusses the connectivity of nanotechnology to the more traditional scientific disciplines as well as emerging technologies. This text can serve as an introduction to the nanoscale for science, computer science, and engineering disciplines. It can also provide a valuable foundation for disciplines such as industrial hygiene, architecture, sociology, ethics, and the humanities. There does not exist an educational discipline, market segment, or career avenue which will not be impacted by nanotechnology.

Colorectal cancer (CRC) is a major global health challenge as the third leading cause for cancer related mortalities worldwide. Despite advances in therapeutic strategies, the five-year survival rate for CRC patients has remained the same over time due to the fact that patients are often diagnosed in advanced metastatic stages. Drug resistance is another common reason for poor prognosis. Researchers are now developing advanced therapeutic strategies such as immunotherapy, targeted therapy, and combination nanotechnology for drug delivery. In addition, the identification of new biomarkers will potentiate early stage diagnosis.This book is the third of three volumes on recent developments in colorectal diagnosis and therapy. Each volume can be read on its own, or together. Each volume focuses on different novel therapeutic advances, biomarkers, and identifies therapeutic targets for treatment. Written by leading international experts in the field, coverage addresses the role of diet habits and lifestyle in reducing gastrointestinal disorders and incidence of CRC. Chapters discuss current and future diagnostic and therapeutic options for colorectal cancer patients, focusing on immunotherapeutics, nanomedicine, biomarkers, and dietary factors for the effective management of colon cancer.

The book covers a range of topics dealing with emerging computing technologies which are being developed in response to challenges faced due to scaling CMOS technologies. It provides a sneak peek into the capabilities unleashed by these technologies across the complete system stack, with contributions by experts discussing device technology, circuit, architecture and design automation flows. Presenting a gradual progression of the individual sub-domains and the open research and adoption challenges, this book will be of interest to industry and academic researchers, technocrats and policymakers.Chapters'Innovative Memory Architectures Using Functionality Enhanced Devices'and'Intelligent Edge Biomedical Sensors in the Internet of Things (IoT) Era'are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

Oxidative Eustress in Exercise Physiology unravels key physiological responses and adaptations to different redox-regulated exercise paradigms at the cell, tissue, and whole-body level in model systems and humans in health and disease. While the mechanistic details are still unclear, key intracellular redox indices seem to be dysregulated with age. Consequently, beneficial molecular responses to acute endurance exercise decline in older individuals. Recent research suggests that manipulating mitochondrial redox homeostasis by supplementing with the mitochondria-targeted coenzyme Q10 for six weeks markedly improves physical function in older adults; i.e. it may be possible to maximise the benefits of exercise by manipulating the redox environment. The research described in this book suggests that significant translational potential exists with respect to cardiovascular disease, neurodegeneration and cancer. An international team of researchers documents the importance of redox biology in health and disease, especially when exercise is a clinically useful tool for the treatment of many diseases and conditions.Features Defines essential redox biology reactions and concepts in exercise physiology Assesses key redox parameters in an in vivo human exercise context Identifies the challenges, opportunities and boundaries of current knowledge Includes a critique of the underlying mechanisms Summarises examples of translationally important research relating to disease states Related TitlesDraper, N. & H. Marshall. Exercise Physiology for Health and Sports Performance (ISBN 978-0-2737-7872-1)Wackerhage, H., ed. Molecular Exercise Physiology: An Introduction (ISBN 978-0-4156-0788-9)

Comprehensive Clinical Psychology, Second Edition, 11 Volume Set brings together important information in the field, making this reference a current state-of-the-art of contemporary research and discussion. The book covers foundational history, professional and training issues, clinical research considerations and methods, assessments and treatments for clinical conditions experienced across the lifespan, clinical considerations for diverse populations, and emerging trends and future directions. In addition, this new release focuses on key areas, such as the emergence of new professional and training issues, new research and statistical approaches to clinical psychology, changes to the manner in which various mental health conditions are conceptualized, and more. Readers will find this to be an ideal, one-stop, comprehensive resource in clinical psychology that is thoroughly modernized to include all recent advances in the field. - Provides an update to this much-loved classic reference work with all the scientific advances of the past 20 years - Presents comprehensive and authoritative articles on all aspects of clinical psychology - Offers readers a'one-stop'resource for access to a wealth of information that will fully support their research and activities - Written by leading experts in psychology across the globe, thus ensuring the knowledge within is easily understood by, and applicable to, a large audience

Es ist wichtig die „Corona-Pandemie“ aus der Perspektive verschiedener Disziplinen zu betrachten. Denn eine „Lösung“ kann letztlich nur gesellschaftlich verantwortet und nicht aus der Logik einer Disziplin, z. B. der Medizin, begründet werden. Was entstanden ist aus den „Corona-Impulsen“ während des ersten Lockdowns in Deutschland im März 2020, hat sich zu einem Zeitzeugnis „nach dem ersten Hype“ entwickelt: Aus multiperspektivischer Sicht (philosophischer, soziologischer, ethnologischer, theologischer und pflegewissenschaftlicher) wird ein Blick auf die Corona-Pandemie und auf ihre langfristigen Folgen und die sich daraus ergebenden Bedarfe geworfen. „Wir haben die Pflegefachkräfte in der Corona-Krise zweimal im Stich gelassen: In der ersten Welle haben sich viele im Dienst am Menschen infiziert, weil Masken, Schutzkleidung und Konzepte fehlten. Viele von ihnen leiden bis heute unter Long Covid, was nicht als Berufskrankheit anerkannt ist. Wenn wir weiter so ignorant mit der größten und wichtigsten Gruppe im Gesundheitswesen umgehen, dürfen wir uns nicht wundern, wenn sie uns jetzt und erst recht in Zukunft überall fehlt. Mit meiner Stiftung Humor Hilft Heilen machen wir seit Jahren Workshops für die Pflege, um die seelische Gesundheit für Pflegekräfte zu stärken. Dieses Buch ist wichtig, weil es auf dieses Dilemma aus verschiedenen Perspektiven hinweist und Lösungen aufzeigt.“ Dr. Eckart von Hirschhausen, Gründer der Stiftung Humor Hilft Heilen, die sich seit 2008 für mehr Menschlichkeit in der Medizin einsetzt und „Begegnungen auf Augenhöhe – mit Augenzwinkern“ ermöglicht.

Qui étaient les « allumettières » de l'usine de pâte et papier E. B. Eddy de Hull? De jeunes femmes exploitées ou des militantes syndicales engagées? Entre 1854 et 1928, ces ouvrières chargées de fabriquer 90% des allumettes du pays ont exercé un métier éreintant et extrêmement dangereux en raison des risques d'incendie et des produits chimiques toxiques qu'elles manipulaient. Les conséquences furent désastreuses pour elles, et il n'est guère surprenant que ces femmes aient déclenché le tout premier conflit syndical féminin au Québec.Dans cette première étude complète sur les allumettières de Hull, l'historienne Kathleen Durocher raconte la fascinante histoire de cette main-d'œuvre anonyme. Pour ce faire, elle met à contribution les recensements canadiens, les archives gouvernementales, privées et paroissiales, ainsi que de nombreux articles de revues scientifiques et de journaux à grand tirage.Durocher dresse ainsi un profil démographique des allumettières et propose des sections dédiées à la vie quotidienne de ces femmes ; leur rôle au sein de la classe ouvrière ; leurs fonctions dans la manufacture ; leurs conditions de travail, les dangers de l'emploi (notamment ceux associés au phosphore blanc) ; et leurs activités syndicales, de 1918 à 1928 – lorsque l'usine a quitté Hull.Tragique et inspirante, l'histoire des allumettières marque l'histoire de la région et du pays depuis plus d'un siècle, mais demeure trop peu connue. Avec ce livre, elle est enfin tirée des oubliettes.

Behavioral Neuroscience is a relatively recent discipline which unifies different fields encompassing Cognitive Psychology, Cognitive Science, Clinical Neurology, Neuroanatomy, and Neurophysiology. Encyclopedia of Behavioral Neuroscience, Three Volume Set is a comprehensive, multidisciplinary work written by the best experts in the field, addressing the relationship between the neurological and biological basis of behavior and models of cognition, spanning from perception to memory and covering phenomena that occur in human and other animals. Published in 2010, it comprised 212 articles and was a unique and essential resource for students and professionals in several fields including neuroscience, psychology, neurology, psychiatry, and cognitive science. It was by far the most comprehensive reference work available addressing the advances in all the field of behavioral neuroscience. It does however, now need revising with the latest science. The new edition will again cover the relationship between brain and behavior, both in humans and other animals, as well as mental and brain disorders. This new edition spans accross three volumes, 250 chapters and approximately 2000 pages. It will build on the foundations of the first edition by thoroughly updating all current articles with the latest research that has developed in the last decade. In addition, 40 brand new articles on the hottest topics within behavioral neuroscience will be added, covering areas such as advances in behavioral genetics and epigenetics, cognitive ageing, neuroepidemiology, social neuroscience, as well as the upsurge of new technologies like diffusion tensor imaging or transcranial direct current stimulation. The result will be an all-encompassing one-stop interdisciplinary major reference work on how the brain and its disorders influence behavior, perfect for neuroscience students, clinicians and scientists interested in knowing more about behavior from a biological perspective. - Much-loved classic reference work fully revised with all the scientific advances of the last decade - Comprehensive and authoritative articles on all aspects of behavioural neuroscience - Offers readers a'one-stop'resource for access to a wealth of information to fully support their research and activities in this area - Chapters written by leading experts in neuroscience across the globe, thus ensuring the knowledge within is easily understood by and applicable to a large audience - Articles intuitively and meticulously organized into 10 coherent sections on key topics, making it easier for the reader to access relevant information quickly - Lists of key references and further reading for each article means that related content will be easier to find, and latest/key research in the field will be highlighted

Epigenetics in Psychiatry, Second Edition covers all major areas of psychiatry in which extensive epigenetic research has been performed, fully encompassing a diverse and maturing field, including drug addiction, bipolar disorder, epidemiology, cognitive disorders, and the uses of putative epigenetic-based psychotropic drugs. Uniquely, each chapter correlates epigenetics with relevant advances across genomics, transcriptomics, and proteomics. The book acts as a catalyst for further research in this growing area of psychiatry. This new edition has been fully revised to address recent advances in epigenetic understanding of psychiatric disorders, evoking data consortia (e.g., CommonMind, ATAC-seq), single cell analysis, and epigenome-wide association studies to empower new research. The book also examines epigenetic effects of the microbiome on psychiatric disorders, and the use of neuroimaging in studying the role of epigenetic mechanisms of gene expression. Ongoing advances in epigenetic therapy are explored in-depth. - Fully revised to discuss new areas of research across neuronal stem cells, cognitive disorders, and transgenerational epigenetics in psychiatric disease - Relates broad advances in psychiatric epigenetics to a modern understanding of the genome, transcriptome, and proteins - Catalyzes knowledge discovery in both basic epigenetic biology and epigenetic targets for drug discovery - Provides guidance in research methods and protocols, as well how to employ data from consortia, single cell analysis, and epigenome-wide association studies (EWAS) - Features chapter contributions from international leaders in the field

From traditional brick and mortar to new start-ups, businesses are harnessing the power of digital enterprise as a cost-effective model to deliver goods and services online. Digital enterprise strategy is adopted for transforming business, streamlining processes, and making the best use of online technologies to enhance interaction with customers and employees and deliver excellent customer experience in real time. Digital enterprises increasingly need digital workers to establish greater digital skills to bear on every activity and to drive management, strategy, and innovation, which are key for digital enterprise transformation. The Handbook of Research on Management and Strategies for Digital Enterprise Transformation is a crucial reference source that discusses leveraging technology for the customers', employees', and suppliers'benefit, as well as integrating complex processes to management, marketing, production, manufacturing, and financial systems. Combining management, strategy, technology, and digital enterprise topics into one book provides the reader with a holistic understanding of the new developments in these emerging fields. This study will also include key topics of interest on how to address structural changes underway in the local and global business environment for digital enterprise transformation. Featuring research on topics such as e-commerce, organizational learning, and agile management, this book is ideally designed for business professionals, policymakers, researchers, students, and managers.

From its early beginnings in the 1960s, the academic field of biochemistry of exercise has expanded beyond examining and describing metabolic responses to exercise and adaptations to training to include a wide understanding of molecular biology, cell signalling, interorgan communication, stem cell physiology, and a host of other cellular and biochemical mechanisms regulating acute responses and chronic adaptations related to exercise performance, human health/disease, nutrition, and cellular functioning.The Routledge Handbook on Biochemistry of Exercise is the first book to pull together the full depth and breadth of this subject and to update a rapidly expanding field of study with current issues and controversies and a look forward to future research directions. Bringing together many experts and leading scientists, the book emphasizes the current understanding of the underlying metabolic, cellular, genetic, and cell signalling mechanisms associated with physical activity, exercise, training, and athletic performance as they relate to, interact with, and regulate cellular and muscular adaptations and consequent effects on human health/disease, nutrition and weight control, and human performance.With more emphasis than ever on the need to be physically active and the role that being active plays in our overall health from a whole-body level down to the cell, this book makes an important contribution for scholars, medical practitioners, nutritionists, and coaches/trainers working in research and with a wide range of clients. This text is important reading for all students, scholars, and others with an interest in health, nutrition, and exercise/training in general.

Global health is a rapidly emerging discipline with a transformative potential for public policy and international development. Emphasizing transnational health issues, global health aims to improve health and achieve health equity for all people worldwide. Its multidisciplinary scope includes contributions from many disciplines within and beyond the health sciences, including clinical medicine, public health, social and behavioral sciences, environmental sciences, economics, public policy, law and ethics. This large reference offers up-to-date information and expertise across all aspects of global health and helps readers to achieve a truly multidisciplinary understanding of the topics, trends as well as the clinical, socioeconomic and environmental drivers impacting global health. As a fully comprehensive, state-of-the-art and continuously updated, living reference, the Handbook of Global Health is an important, dynamic resource to provide context for global health clinical care, organizational decision-making, and overall public policy on many levels. Health workers, physicians, economists, environmental and social scientists, trainees and medical students as well as professionals and practitioners will find this handbook of great value.

In dem Sammelband werden verschiedene Schreiblehrkonzepte vorgestellt, um Studierende in das fachspezifische wissenschaftliche Schreiben einzuführen. Die Methoden, Übungen und Zugänge wurden im Qualitätspakt Lehre entwickelt und erprobt. Der Schwerpunkt liegt auf den Herausforderungen des fachspezifischen wissenschaftlichen Schreibens. Die Autorinnen und Autoren präsentieren Lehransätze und evaluieren Maßnahmen im Hinblick auf ihre Wirksamkeit. Außerdem wird diskutiert, wie Lehrende für die Vermittlung fachspezifischen Schreibens vom Scholarship of Teaching and Learning (SoTL) profitieren können. Die Beiträge entstanden im Rahmen der Abschlusstagung des Projekts'richtig einsteigen mit literalen Kompetenzen (LitKom)'.

Bachelorarbeit aus dem Jahr 2021 im Fachbereich Gesundheit - Sportwissenschaft, Note: 1,7, Gottfried Wilhelm Leibniz Universität Hannover, Sprache: Deutsch, Abstract: Das Ziel dieses Reviews ist es, einen systematischen Überblick über den Einfluss einer Vitamin-E-Supplementierung auf die Genesung in verschiedenen Populationen zu geben. Die Datenbanken PubMed und BISp-Surf wurden systematisch nach englisch- oder deutschsprachigen Studien durchsucht. Der erste Schritt wurden Duplikate zu entfernen und hinsichtlich der Erfüllung bestimmter Ein- und Ausschlusskriterien zu bewerten. Es blieben zehn Studien übrig, die die Kriterien vollständig erfüllten. Die meisten Studien zeigten keine Auswirkungen auf die Wiederherstellung der Leistungsfähigkeit der Probanden. Dennoch gab es Einschränkungen, die den Vergleich der Studien sehr erschwerten. Die eingenommenen Mengen variierten stark, ebenso wie Alter, Aktivitätsstatus und Trainingsprogramm. In den letzten Jahren hat der Konsum von Nahrungsergänzungsmitteln wie Antioxidantien zugenommen. Die REGman-Broschüre zeigt bereits den Einfluss verschiedener Maßnahmen. Die aktuellsten Übersichtsarbeiten zur Wirkung von Vitamin E wurden vor 2010 veröffentlicht. Aus diesem Grund muss sie aufgrund des erhöhten Konsums bei verschiedenen Bevölkerungsgruppen aktualisiert werden.

Depression, a highly common clinical disorder, is an important and clinically relevant topic for both clinical researchers and practitioners to address, because of its prevalence, impact on the individual and society, association with other mental and physical health problems and the social contexts in which it develops. Depression ranks in Germany and central Europe as the third among the leading mental disorders and world-wide is a leading cause of disability. It is estimated that 8.3% of the German population is depressed within a year (11.2% women, 5.5% men). These statistics mean that 4 million people per year are depressed in Germany alone (one year prevalence). According to the WHO, over 300 million people world-wide experience depression and in the USA the financial burden of this disorder, due to disability and work absenteeism, reaches Depression is also becoming more frequent over time and has a high risk of recidivism –particularly since its most common form, Major Depressive Disorder (DSM-5; ICD10) tends to occur in episodes. For example, 20% to 40% of people become depressed again within two years after their first depressive episode, meaning that a major aim of any therapeutic intervention should be to prevent future relapses. Depression also shows very high comorbidities with other mental and physical health conditions. Its overlap with anxiety pathology is so high that clinicians are concerned with whether the two disorder categories are indeed distinct or if they show substantial etiological overlap. Depression is also associated with heart disease and even cancer, making it a risk factor for mortality and morbidity that needs to be identified early and addressed effectively. In addition to Major Depressive Disorder, the often severe Bipolar Disorder, and the chronic form of Depression referred to as dysthymia are additional mood disorders that among them require careful differential diagnosis. They also lead to questions regarding their common or distinct etiological mechanisms. In order to gain a better understanding of Depression as a clinical disorder, one needs to look at it as a multifaceted phenomenon. Depression is a neurobehavioral condition, and one has to be up to date and have solid understanding of its biological substrate, at a genetic, neuronal, hormonal and pharmacological level. Depression is also a socio-demographic phenomenon, and one needs to examine its epidemiology, that might contain significant cues towards its clearer understanding. It is more prevalent, for example, in certain regions, climates, age groups and genders (much more prevalent in women, with age of appearance in young adulthood but also presents as a significant problem for youth and the elderly), is associated with stereotypes and stigma and can be the aftermath of crises, trauma and loss. The etiology of Depression remains under scrutiny, though recently much more knowledge is emerging from contemporaryneuroimaging, genotyping and data science methods. Different neural and behavioral systems may be involved contributing to the significant heterogeneity within the disorder. Social roles, stressors, attachment patterns, family support and social networks, and individual (e.g. gender linked) vulnerabilities may contribute significantly towards increasing risk for developing depression. Different therapeutic approaches, like those stemming from the psychoanalytic/psychodynamic perspectives and those stemming from the cognitive/behavioral (2nd and 3rd wave) tradition focus on the components of etiology considered most dominant. As science progresses with clearer evidence regarding the important etiological factors and their interactions, these different perspectives, each with its own contribution, may need to take new developments into consideration, adapt and even begin to converge. These different aspects of the topic of Depression, which ar

With the end of Moore's law and the emergence of new application needs such as those of the Internet of Things (IoT) or artificial intelligence (AI), neuro-inspired, or neuromorphic, information processing is attracting more and more attention from the scientific community. Its principle is to emulate in a simplified way the formidable machine to process information which is the brain, with neurons and artificial synapses organized in network. These networks can be software – and therefore implemented in the form of a computer program – but also hardware and produced by nanoelectronic circuits. The �material� path allows very low energy consumption, and the possibility of faithfully reproducing the shape and dynamics of the action potentials of living neurons (biomimetic approach) or even being up to a thousand times faster (high frequency approach). This path is promising and welcomed by the major manufacturers of nanoelectronics, as circuits can now today integrate several million neurons and artificial synapses.

This book presents the proceedings of the virtual conference NeuroIS Retreat 2020, June 2–4, hosted in Austria, reporting on topics at the intersection of information systems (IS) research, neurophysiology and the brain sciences. Readers will discover the latest findings from top scholars in the field of NeuroIS, which offer detailed insights on the neurobiology underlying IS behavior, essential methods and tools and their applications for IS, as well as the application of neuroscience and neurophysiological theories to advance IS theory.

Lassen sich Dritte an eine Schiedsvereinbarung binden? Die subjektive Reichweite von Schiedsvereinbarungen bildet nicht erst seit der Dow-Chemical-Entscheidung den Gegenstand vertiefter Diskussionen. Ungeachtet der praktischen Dimension dieser Frage, fehlt es neben sachrechtlichen Regelungen insbesondere an maßgeblichen Kollisionsnormen zur Bestimmung des hierfür anwendbaren Rechts. Im Kern der Untersuchung steht die Frage, nach welchen Rechtsregeln die Bindung Dritter an eine Schiedsvereinbarung zu bemessen ist und welche Kollisionsnormen in grenzüberschreitenden Fallkonstellationen diesbezüglich zur Anwendung zu bringen sind. Dabei hat sich gezeigt, dass sich die prozessuale Drittbindung auf Rechtsinstitute des materiellen Rechts stützen lässt und sich die kollisionsrechtlichen Interessen ausschließlich im Wege verschiedener Sonderanknüpfungen verwirklichen lassen. Diese Erkenntnisse ließen sich schließlich in ein praktisch handzuhabendes Prüfungsschema übersetzen.

The need for policy coherence between trade and health has never been greater, yet few public health workers are equipped to navigate this complex field. This book aims to fill this gap, providing a focused and readable introduction to the topic. It introduces the principles underpinning trade treaties and examines the implications of trade rules for health services and access to medicines, unhealthy commodities, labour rights and the environment. It explores the trade policy making process, methods for trade and health research, and recommendations for strengthening policy coherence.

With the launch of the Quantum Technology Flagship Programme by the European Commission, developments in the realization of new technologies based on quantum physics have been recognized as a priority. These are important for cryptographic techniques for telecommunications security, new computing hardware that can solve problems so far inaccessible even to the latest generation of supercomputers, and precision standards and sensors with important applications ranging from materials science to medical diagnostics. This book presents a collection of lectures from the International School of Physics Enrico Fermi on Nanoscale Quantum Optics, held in Varenna, Italy, from 23 – 28 July 2018. The course was attended by 60 students, researchers and lecturers, and provided an opportunity to train a new generation of scientists on topics that promise great innovations in science and technology. Included here are 9 lectures and seminars and 3 poster contributions from the school. Subjects covered include: basic concepts for quantum optics and quantum technologies; materials for quantum nanophotonics; quantum optics and non-classical light generation; creating quantum correlations between quantum-dot spins; platforms for telecom-entangled photon sources; nanoscale sensing and quantum coherence; and nano-optomechanics, among others. The book offers a valuable overview of the state-of-the-art and current trends in nanoscale quantum optics. It will be invaluable for all those with an interest in this subject.

There is no question that our environment has changed dramatically over the past few decades. The influx of thousands of toxic chemicals that seep into every aspect of our lives wreaking havoc on our bodies can seem daunting, but research now shows that by making simple changes, we can dramatically reduce exposures to many harmful chemicals that we eat, breathe, and lather on our skin. Non-Toxic is a practical guide to living healthier in our modern environment. It teaches how to reduce chemical and radiation exposures by recognizing potential threats and paying attention to what you eat, breathe, and put onto your skin. Written in clear, easy-to-understand language and based on scientific evidence, this book is filled with resources, tools, tear-off sheets, recipes, and practical, cost-effective tips designed to help you: · Understand and decode product and food labels · Create delicious recipes to help detoxify your body · Choose and prepare food and drinks safely and healthfully · Furnish and clean your home for a healthy indoor environment · Safely disinfect surfaces from COVID-19 · Create do-it-yourself cleaning product recipes · Choose safer personal care products and cosmetics · Reduce exposure to pesticides in and around your home · Ensure safe drinking water for you, your family and pets · Reduce exposure to EMF radiation from cell phones, laptops and other tech toys · Make informed decisions about toys, baby products, and other environmental issues affecting your children Written by a board-certified Rheumatologist and Integrative Medicine Physician, and a renowned PhD professor of neuro- and reproductive biology, Non-Toxic is designed to be referred to again and again for its relevant, cost-effective, and practical ways to reduce exposure and thereby lower risk for developing a variety of environmentally associated illnesses. ABOUT THE SERIES: From series editor, Andrew Weil, one of the most iconic and trusted names in healthcare today, the Dr. Weil's Healthy Living Guides series discusses caring for common medical conditions and optimizing health from an integrative medical approach. Integrative medicine is defined as an evidence-based healing-oriented medicine that takes account of the whole person (body, mind, and spirit), including all aspects of lifestyle. It emphasizes the therapeutic relationship and makes use of all appropriate therapies, conventional, alternative, and complementary.

The COVID-19 pandemic has increased the focus on health informatics and healthcare technology for policy makers and healthcare professionals worldwide. This book contains the 110 papers (from 160 submissions) accepted for the 18th annual International Conference on Informatics, Management, and Technology in Healthcare (ICIMTH 2020), held virtually in Athens, Greece, from 3 – 5 July 2020. The conference attracts scientists working in the field of Biomedical and Health Informatics from all continents, and this year it was held as a Virtual Conference, by means of teleconferencing, due to the COVID-19 pandemic and the consequent lockdown in many countries around the world. The call for papers for the conference started in December 2019, when signs of the new virus infection were not yet evident, so early submissions were on the usual topics as announced. But papers submitted after mid-March were mostly focused on the first results of the pandemic analysis with respect to informatics in different countries and with different perspectives of the spread of the virus and its influence on public health across the world. This book therefore includes papers on the topic of the COVID-19 pandemic in relation to informatics reporting from hospitals and institutions from around the world, including South Korea, Europe, and the USA. The book encompasses the field of biomedical and health informatics in a very broad framework, and the timely inclusion of papers on the current pandemic will make it of particular interest to all those involved in the provision of healthcare everywhere.

How should we invest precious health resources? At a time when chronic illness is increasing, inequality persists and climate change is starting to impact our health, how can health promotion improve health outcomes across the whole population?Health Promotion in the 21st Century offers a systematic introduction to the principles of health promotion today, and effective planning, implementation and evaluation. The authors review the global, regional and local issues that affect health in Australia, and show how social, economic, political and educational elements in society contribute to population health and wellbeing.Throughout, the authors emphasise that health promotion needs multiple solutions, and that health professionals should seek out strategic opportunities and partnerships. They consider the issues facing vulnerable groups - such as Aboriginal and Torres Strait Islander people, those with mental health issues, and the aged - and suggest a variety of innovative tools for working with particular populations. They also focus on strategies to ensure programs remain vibrant and sustainable in the longer term.With case studies and activities in each chapter, Health Promotion in the 21st Century is an essential resource for anyone seeking to build a career in health promotion.

Developing countries are persistently looking for efficient and cost-effective methods for transforming their communities into smart cities. Unfortunately, energy crises have increased in these regions due to a lack of awareness and proper utilization of technological methods. These communities must explore and implement innovative solutions in order to enhance citizen enrollment, quality of government, and city intelligence. IoT Architectures, Models, and Platforms for Smart City Applications provides emerging research exploring the theoretical and practical aspects of transforming cities into intelligent systems using IoT-based design models and sustainable development projects. This publication looks at how cities can be built as smart cities within limited resources and existing advanced technologies. Featuring coverage on a broad range of topics such as cloud computing, human machine interface, and ad hoc networks, this book is ideally designed for urban planners, engineers, IT specialists, computer engineering students, research scientists, academicians, technology developers, policymakers, researchers, and designers seeking current research on smart applications within urban development.

Major depressive disorder (MDD) is a serious, debilitating, life-shortening illness that affects many persons of all ages and backgrounds. The lifetime risk for MDD is 7-12% for men and 20-25% for women (Kessler et al., 2003). MDD is a disabling disorder that costs the U.S. over $200 billion per year in direct and indirect costs (Greenberg et al., 2015), and is the leading cause of disability worldwide (WHO, 2018). Depression also has detrimental effects on all aspects of social functioning (e.g., self-care, social role, and family life, including household, marital, kinship, and parental roles). While there have been several treatments that are efficacious, many individuals suffering from depression experience life-long challenges due to the chronic and episodic nature of the disease. Identifying strategies to find the right treatments for the right patients is critical. Ongoing research has explored the importance of examining physiologic biomarkers, as well as clinical characteristics to gain a better understanding of subtypes of depression, which will lead to improved treatments and better outcomes. This book provides an introduction to the etiology and pathophysiology of depression, common comorbidities and differential diagnoses, pharmacotherapy strategies, psychotherapeutic and neuromodulation interventions, novel and non-traditional treatment strategies, and considerations in special populations.