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The first of its kind, this comprehensive resource integrates cellular mechanobiology with micro-nano techniques to provide unrivalled in-depth coverage of the field, including state-of-the-art methods, recent advances, and biological discoveries. Structured in two parts, the first part offers detailed analysis of innovative micro-nano techniques including FRET imaging, electron cryo-microscopy, micropost arrays, nanotopography devices, laser ablation, and computational image analysis. The second part of the book provides valuable insights into the most recent technological advances and discoveries in areas such as stem cell, heart, bone, brain, tumor, and fibroblast mechanobiology. Written by a team of leading experts and well-recognised researchers, this is an essential resource for students and researchers in biomedical engineering.

Global warming, pollution, food and water shortage, cyberspace insecurity, over-population, land erosion, and an overburdened health care system are major issues facing the human race and our planet. These challenges have presented a mandate to develop “natural” or “green” technologies using nature and the living system as a guide to rationally design processes, devices, and systems. This approach has given rise to a new paradigm, one in which innovation goes hand-in-hand with less waste, less pollution, and less invasiveness to life on earth. Bioinspiration has also led to the development of technologies that mimic the hierarchical complexity of biological systems, leading to novel highly efficient, more reliable multifunctional materials, devices, and systems that can perform multiple tasks at one time. This multi-volume handbook focuses on the application of biomimetics and bioinspiration in medicine and engineering to produce miniaturized multi-functional materials, devices, and systems to perform complex tasks. Our understanding of complex biological systems at different length scales has increased dramatically as our ability to observe nature has expanded from macro to molecular scale, leading to the rational biologically-driven design to find solution to technological problems in medicine and engineering.The following three-volume set covers the fields of bioinspired materials, electromechanical systems developed from concepts inspired by nature, and tissue models respectively.The first volume focuses on the rational design of nano- and micro-structured hierarchical materials inspired by the relevant characteristics in living systems, such as the self-cleaning ability of lotus leaves and cicadas'wings; the superior walking ability of water striders; the anti-fogging function of mosquitoes'eyes; the water-collecting ability of Namib Desert Beetles and spider silk; the high adhesivity of geckos'feet and rose petals; the high adhesivity of mussels in wet aquatic environments; the anisotropic wetting of butterflies'wings; the anti-reflection capabilities of cicadas'wings; the self-cleaning functionality of fish scales; shape anisotropy of intracellular particles; the dielectric properties of muscles; the light spectral characteristics of plant leaves; the regeneration and self-healing ability of earthworms; the self-repairing ability of lotus leaves; the broadband reflectivity of moths'eyes; the multivalent binding, self-assembly and responsiveness of cellular systems; the biomineral formation in bacteria, plants, invertebrates, and vertebrates; the multi-layer structure of skin; the organization of tissue fibers; DNA structures with metal-mediated artificial base pairs; and the anisotropic microstructure of jellyfish mesogloea. In this volume, sensor and microfluidic technologies combined with surface patterning are explored for the diagnosis and monitoring of diseases. The high throughput combinatorial testing of biomaterials in regenerative medicine is also covered.The second volume presents nature-oriented studies and developments in the field of electromechanical devices and systems. These include actuators and robots based on the movement of muscles, algal antenna and photoreception; the non-imaging light sensing system of sea stars; the optical system of insect ocellus; smart nanochannels and pumps in cell membranes; neuromuscular and sensory devices that mimic the architecture of peripheral nervous system; olfaction-based odor sensing; cilia-mimetic microfluidic systems; the infrared sensory system of pyrophilous insects; ecologically inspired multizone temperature control systems; cochlea and surface acoustic wave resonators; crickets'cercal system and flow sensing abilities; locusts'wings and flapping micro air vehicles; the visual motion sensing of flying insects; hearing aid devices based on the human cochlea; the geometric perception of tortoises and pigeons; the organic matter sensing capability of ca

Nanomaterials have become a key component for energy-related applications. Their design principle, synthesis and applications are well discussed in various scientific and engineering books, but a gap remains in discussions regarding the application of cutting-edge X-ray techniques to these materials. This volume provides insights from the latest development of X-ray techniques to investigate nanomaterials in specific energy fields, bridging the gap between X-ray analytical scientists and material researchers.We aim to provide researchers with a tool to choose suitable X-ray techniques, carry them out with the right procedure, and analyze the data to give the best reliable results. The approach is microscopic and specific. Among the applications emphasized by the chapters in this book are x-ray techniques in heterogeneous catalysis, electrocatalysis for fuel cells, photocatalysis for water splitting and carbon dioxide reduction, organic photovoltaics, and other energy-related applications.

This book is about the hope of the Church in the secular age uninterested in Christianity. In this setting, the theology and practice of missional church is a critical topic. We introduce urban churches in South Korea conducting maeul ministry, Korea's context-specific practice of the missional church in local communities. The cases are followed by theological reflections to connect the practice with the theology of missional church. These stories of maeul ministry present various examples of church involvement and leadership in social issues of the environment, healthcare, education, and community-building, offering new hope and challenge for the world church. We hope this book will provide new insight and wisdom to church communities and pastors who pursue and practice the missional essence of the church in these changing times.

Smart drug delivery refers to a targeted drug delivery or precision drug delivery system that allows drugs to be administered to a specific location in the body or at a specific time with enhanced precision and control. This approach has several advantages, including maximizing the therapeutic effects of a drug while minimizing side effects.This book presents various stimuli-responsive micro- and nanomaterials for pharmaceutical industries. This volume: Covers the global market perspective of micro- and nano-smart materials in pharmaceutical industries. Details various processing routes. Discusses mechanisms for target release. Addresses applications in oral drug delivery, anticancer agents, anti-tumor drug delivery, and drugs for management of infection. This reference work is written to support researchers in the fields of materials engineering and biotechnology with the goal of improving the diagnosis and treatment of disease and patient quality of life.

In this open access book, Mikael Hård tells a story of how people around the world challenged the production techniques and products brought by globalization. Retaining their autonomy and freedom, creative individuals selectively adopted or rejected modern gadgets, tools, and machines. In standard historical narratives, globalization is portrayed as an unstoppable force that flattens all obstacles in its path. Modern technology is also seen as inexorable: in the nineteenth century, steamships, telegraph lines, and Gatling guns are said to have paved the way for colonialism and other forms of dominating people and societies. Later, shipping containers and computer networks purportedly pulled the planet deeper into a maelstrom of capitalism. Hård discusses instances that push back against these narratives. For example, in Soviet times, inhabitants of Samarkand, Uzbekistan, preferred to remain in—and expand—their own mud-brick houses rather than move into prefabricated, concreteresidential buildings. Similarly, nineteenth-century Sumatran carpenters ignored the saws brought to them by missionaries—and chose to chop down trees with their arch-bladed adzes. And people in colonial India successfully competed with capitalist-run Caribbean sugar plantations, continuing to produce their own muscovado and sell it to local consumers. This book invites readers to view the history of technology and material culture through the lens of diversity. Based on research funded by the European Research Council and conducted in the Global South, Microhistories of Technology: Making the World shows that the spread of modern technologies did not erase artisanal production methods and traditional tools.

This volume includes five chapters that present recent updates in cardiovascular research from around the world. Chapter One discusses how histamine is transported from the gut via the bloodstream to the heart and puts forward novel evidence that histamine can be produced in the heart itself. Chapter Two provides an analytical comparison of induced pluripotent stem cells, mesenchymal stem cells, and cardiosphere-derived cells commonly used for clinical cardiac applications. Chapter Three compares outcomes of patients who underwent transcatheter aortic valve implantation with those who underwent sutureless aortic valve replacement. Chapter Four analyzes changes in electrocardiogram leads, reflecting manifestation and development of acute and chronic myocardial ischemia. Lastly, Chapter Five reviews existing and upcoming cardiac magnetic resonance imaging techniques to evaluate systemic and pulmonary impedance in healthy individuals and cardiovascular disease states.

3D printing came into existence in the early 1980s as additive manufacturing and, over the years, the technology has grown by leaps and bounds. It gained huge popularity in the 2000s, when its importance came into the limelight and its role was explored to help improve capability of humans. The additive technology is being employed in different fields and affecting different aspects of human lives. In the medical field, 3D-printing was seen as one of the biggest breakthroughs and it slowly became an integral part of mainstream medical practice. This book explores the growth and advancement in 3D printing technology in different areas of healthcare and how it is being employed to help in improving patient care with better quality, customized designs and lower costs thereby providing durability and patient comfort. It will provide insight to budding researchers and students to explore the field further.

Water is an indispensable resource for our society. Essential to sustaining life and economic prosperity, water is also the basic component for manufacturing almost everything to keep society alive, including energy, food, clothing, cars, and electronics, among many other examples. It is, thus, an integral part of our lives beyond simply quenching our thirst. In addition, our future economy and security highly depend upon the availability of clean water. Yet given its critical importance, there is a limited supply of renewable freshwater across the globe and there is no substitute. Global population and economic growth, urbanization, and climate change further exacerbate the increasing stress on freshwater supplies. As such, society urgently needs to find the scientific and engineering solutions to more efficiently manage our precious water resources. The volumes of this multi-volume reference cover the latest scientific advancements and solutions in managing and treating this crucial resource.Related Link(s)

World Scientific Reference on Plasmonic Nanomaterials: Principles, Design and Bio-applications is a book collection that encompasses multiple aspects of the exciting and timely field of nanoplasmonics, under the coordination of international plasmonic nanomaterials expert, Dr Luis Liz-Marzán. Plasmonics has a long history, from stained glass in ancient cathedrals, through pioneering investigations by Michael Faraday, all the way into the nanotechnology era, where it blossomed into an extremely active field of research with potential applications in a wide variety of technologies.Given the breadth of the materials, phenomena and applications related to plasmonics, this Reference Set offers a collection of chapters within dedicated volumes, focusing on the description of selected phenomena, with an emphasis in chemistry as an enabling tool for the fabrication of, often sophisticated, plasmonic nanoarchitectures and biomedicine as the target application.Basic principles of surface plasmon resonances are described, as well as those mechanisms related to related phenomena such as surface-enhanced spectroscopies or plasmonic chirality. Under the guidance of theoretical models, wet chemistry methods have been implemented toward the synthesis of a wide variety of nanoparticles with different compositions and tailored morphology. But often the optimal nanoarchitecture requires post-synthesis treatments, including functionalization of nanoparticle surfaces, application of external stimuli toward self-assembly into well-defined supraparticle structures and so-called supercrystals. All such nanomaterials can find applications in various biomedical aspects, most often in relation to diagnosis, through either the detection of disease biomarkers at extremely low concentrations or the design of bioimaging methods for in vivo monitoring. Additionally, novel therapeutic tools can also profit from plasmonic nanomaterials, such as photothermal therapy or nanocatalysis.The reference set thus offers comprehensive information of an extremely active subset within the world of plasmonic nanomaterials and their applications, which aims at not just collecting existing knowledge but also promoting further research and technology transfer into the market and the clinic.

Musculoskeletal Tissue Engineering introduces the fundamental concepts and translational applications of musculoskeletal tissue engineering, in combination with emerging technologies and materials. Sections discuss Tissues and Technologies, covering a range of musculoskeletal tissues, including bone, cartilage, ligament and more. Each chapter in this section details core tissue engineering principles specific to each tissue type. Next, a Technologies section looks at the range of biomaterials used in musculoskeletal tissue engineering, focusing on biocompatibility of materials and interactions at the material-tissue interface. Other chapters cover nanotechnology, 3D printing, gene therapy, tissue chips, and more. This book offers an advanced reference text for researchers in biomedical engineering, materials science and regenerative medicine. - Details various materials and cutting-edge technologies for musculoskeletal tissue engineering - Covers a range of musculoskeletal tissues, including bone, cartilage, ligament, tendon, meniscus, and more - Provides a balance between basic concepts and translational applications for a broad audience

Of the 121,000 people on donor lists in the U.S., over 100,000 need kidney transplants and thousands die each year while waiting. Bioprinting aspires to build healthy kidney tissue from a patient's own cells and transplant this to boost failing kidneys without fear of rejection... As the 21st century dawned, a handful of inspired scientists tried to use 3D printing to create living human tissue. Their vision was to restore the health of people with intractable injuries, such as worn out cartilage, severed nerves, ailing kidneys, failing hearts—the gamut of human frailties. Their modest success energized others to join the quest. Now, after two decades of ingenious effort and hard work, they have carved out a vibrant new discipline: bioprinting. In Bioprinting: To Make Ourselves Anew, physicist Kenneth Douglas casts an eye over the achievements and future of bioprinting. He explains the science with rigor but with a minimum of technical baggage. This is the first book on the subject written expressly for the lay audience: accessible and even entertaining. Douglas interviewed two dozen bioprinting researchers from around the world, and he enriches the narrative by sharing stories from the scientists behind the science. These contemporary vignettes are complemented by historical accounts of the women and men whose prescient contributions were foundational to the development of bioprinting. The book describes the challenges and accomplishments in the bioprinting of blood vessels, cartilage, skin, bone, skeletal muscle, neuromuscular junctions, liver, heart, lung, kidney, and so-called organs-on-a-chip, as well as the challenges of providing a blood supply and nerves to bioprinted tissues. This is a compelling tale of a work in progress: to imitate nature and help heal people with debilitating afflictions.

Advanced Characterization of Nanostructured Materials — Probing the Structure and Dynamics with Synchrotron X-Rays and Neutrons is a collection of chapters which review the characterization of the structure and internal dynamics of a wide variety of nanostructured materials using various synchrotron X-ray and neutron scattering techniques. It is intended for graduate students and researchers who might be interested in learning about and applying these methods. The authors are well-known practitioners in their fields of research who provide detailed and authoritative accounts of how these techniques have been applied to study systems ranging from thin films and monolayers on solid surfaces and at liquid-air, liquid-liquid and solid-liquid interfaces; nanostructured composite materials; battery materials, and catalytic materials. While there have been a great many books published on nanoscience, there are relatively few that have discussed in one volume detailed synchrotron X-ray and neutron methods for advanced characterization of nanomaterials in thin films, composite materials, catalytic and battery materials and at interfaces. This book should provide an incentive and a reference for researchers in nanomaterials for using these techniques as a powerful way to characterize their samples. It should also help to popularize the use of synchrotron and neutron facilities by the nanoscience community.

The Oxford Guide to the Transeurasian Languages provides a comprehensive account of the Transeurasian languages, and is the first major reference work in the field since 1965. The term'Transeurasian'refers to a large group of geographically adjacent languages that includes five uncontroversial linguistic families: Japonic, Koreanic, Tungusic, Mongolic, and Turkic. The historical connection between these languages, however, constitutes one of the most debated issues in historical comparative linguistics. In the present book, a team of leading international scholars in the field take a balanced approach to this controversy, integrating different theoretical frameworks, combining both functional and formal linguistics, and showing that genealogical and areal approaches are in fact compatible with one another. The volume is divided into five parts. Part I deals with the historical sources and periodization of the Transeurasian languages and their classification and typology. In Part II, chapters provide individual structural overviews of the Transeurasian languages and the linguistic subgroups that they belong to, while Part III explores Transeurasian phonology, morphology, syntax, lexis, and semantics from a comparative perspective. Part IV offers a range of areal and genealogical explanations for the correlations observed in the preceding parts. Finally, Part V combines archaeological, genetic, and anthropological perspectives on the identity of speakers of Transeurasian languages. The Oxford Guide to the Transeurasian Languages will be an indispensable resource for specialists in Japonic, Koreanic, Tungusic, Mongolic, and Turkic languages and for anyone with an interest in Transeurasian and comparative linguistics more broadly.

This book is indexed in Chemical Abstracts ServiceSoft and bio-nanomaterials offer a tremendously rich behavior due to the diversity and tailorability of their structures. Built from polymers, nanoparticles, small and large molecules, peptoids and other nanoscale building blocks, such materials exhibit exciting functions, either intrinsically or through the engineering of their organization and combination of blocks. Thus, it is not surprising that a variety of challenges, for example, in energy storage, environment protection, advanced manufacturing, purification and healthcare, can be addressed using these materials. The recent advances in understanding the behavior of soft matter and biomaterials are being actively translated into functional materials systems and devices, which take advantages of newly discovered and specifically created morphologies with desired properties. This major reference work presents a detailed overview of recent research developments on fundamental and application-inspired aspects of soft and bio-nanomaterials and their emerging functions, and will be divided into four volumes: Vol 1: Soft Matter under Geometrical Confinement: From Fundamentals at Planar Surfaces and Interfaces to Functionalities of Nanoporous Materials; Vol 2: Polymers on the Nanoscale: Nano-structured Polymers and Their Applications; Vol 3: Bio-Inspired Nanomaterials: Nanomaterials Built from Biomolecules and Using Bio-derived Principles; Vol 4: Nanomedicine: Nanoscale Materials in Nano/Bio Medicine.

Soft materials with nanometer scale aspects have been heavily used in biomedical science. Instead of providing a broad introduction of soft materials and their biomedical applications, this book focuses on the preparation of molecular assemblies of biotechnologically relevant biomimetic systems with an emphasis on medical applications.

This book will examine the relevant biological subjects involved in biomimetic microengineering as well as the design and implementation methods of such engineered microdevices. Physiological topics covered include regeneration of complex responses of our body on a cellular, tissue, organ, and inter-organ level. Technological concepts in cell and tissue engineering, stem cell biology, microbiology, biomechanics, materials science, micro- and nanotechnology, and synthetic biology are highlighted to increase understanding of the transdisciplinary methods used to create the more complex, robust biomimetic engineered models. The effectiveness of the new bioinspired microphysiological systems as replacements for existing in vitro or in vivo models is explained through sections that include the protocols to reconstitute three-dimensional (3D) structures, recapitulate physiological functions, and emulate the pathophysiology of human diseases. This book will also discuss how researchers can discover bridge technologies for disease modeling and personalized precision medicine.Features Focuses on cutting edge technologies that enable manipulation of living systems in a spatiotemporal manner. Incorporates research on reverse engineering of comples microenvironmental factors in human diseases. Highlights technologies related to patient-specific personalized medicine and their potential uses. Written by chapter authors who are highly respected researchers in science and engineering. Includes extensive references at the end of each chapter to enhance further study. Hyun Jung Kim is an Assistant Professor in the Department of Biomedical Engineering at The University of Texas at Austin. After receiving hois Ph.D. degree at Yonsei University in the Republic of Korea, he did extensive postdctoral research at both the University of Chicago and the Wyss Institute at Harvard University. These efforts resulted in cutting-edge breakthroughs in synthetic microbial community research and organomimetic human Gut-on-a-Chip microsystem. His research on Gut-on-a-Chip technology leads to the creation of a microfluidic device that mimics the physiology and pathology of the living human intestine. Since 2015, he has explored novel human host-microbiome ecosystems to discover the disease mechanism and new therapeutics in inflammatory bowel disease and colorectal cancers at UT Austin. In collaboration with clinicians, his lab is currently developing disease-oriented, patient-specific models for the advancement in pharmaceutical and clinical fields.

In Zinc Oxide: Production, Properties and Applications, the authors first provide a summary of the natural sources available for the synthesis of zinc oxide nanoparticles, enlisting some plant-mediated synthesized zinc oxide nanoparticles showing promising antimicrobial, antioxidant, cytotoxic and photocatalytic properties. Important technological opportunities and challenges emphasizing the electrical and optoelectronic features of elongated zinc oxide nanoparticle nanosystems are reviewed. The various nonlinear optical phenomenon observed in zinc oxide thin film, inlcuding nonlinear absorption, nonlinear refraction, nonlinear scattering and harmonic generations are introduced. Selected literature on the use of zinc oxide nanoparticles for the immobilization of enzymes is reviewed, as well as the use of zinc oxide nanoparticle/enzyme systems in the fabrication of biosensors. The authors explore transition metal doped zinc oxide nanoparticles for a wide range of catalytic organic reactions, further exploring their catalytic applications for organic transformations at mild reaction conditions. The basic concepts behind the development of nanostructured zinc oxide nanoparticles, including the solid state reaction, hydrothermal method, solvothermal method and co-precipitation method are discussed. Lastly, a facile, eco-friendly synthesis of zinc oxide nanoparticles using the peel extract of Musa paradisiaca L, Punica granatum L, and Citrus reticulata Blanco as bioreducing agent is reported.

The World Scientific Reference of Hybrid Materials is a set of 3 volumes, which covers the fascinating area of materials science at the intersection between purely polymeric, organic or inorganic materials. The rapidly developing research on hybrid materials is largely driven by the steadily increasing need of multifunctional materials in various branches of technology. However, much of the research is also driven by the curiosity of the researchers and the long lasting wish to merge the most beneficial properties of the various materials into one. The flexibility of polymers could, for example, be merged with the electronic conductivity of metals or the mechanical resistance of ceramics, which will be of great value for the industries.This reference covers the areas of synthesis of such hybrid materials, which take benefit from each of the consisting ingredients, and overviews some of the emerging applications based on the materials. Much of the current research is still in its infancy, but hybrid materials are already now considered to be the key enabler for important future developments, for example flexible electronics. With this perspective, this reference aims at giving the general public an overview over the topics of relevance in this field, but also attracting new researchers to this intriguing scientific area.

A bold and unprecedented look at a cutting-edge movement in architectureToward a Living Architecture? is the first book-length critique of the emerging field of generative architecture and its nexus with computation, biology, and complexity. Starting from the assertion that we should take generative architects'rhetoric of biology and sustainability seriously, Christina Cogdell examines their claims from the standpoints of the sciences they draw on—complex systems theory, evolutionary theory, genetics and epigenetics, and synthetic biology. She reveals significant disconnects while also pointing to approaches and projects with significant potential for further development. Arguing that architectural design today often only masquerades as sustainable, Cogdell demonstrates how the language of some cutting-edge practitioners and educators can mislead students and clients into thinking they are getting something biological when they are not. In a narrative that moves from the computational toward the biological and from current practice to visionary futures, Cogdell uses life-cycle analysis as a baseline for parsing the material, energetic, and pollution differences between different digital and biological design and construction approaches. Contrary to green-tech sustainability advocates, she questions whether quartzite-based silicon technologies and their reliance on rare earth metals as currently designed are sustainable for much longer, challenging common projections of a computationally designed and manufactured future. Moreover, in critiquing contemporary architecture and science from a historical vantage point, she reveals the similarities between eugenic design of the 1930s and the aims of some generative architects and engineering synthetic biologists today. Each chapter addresses a current architectural school or program while also exploring a distinct aspect of the corresponding scientific language, theory, or practice.No other book critiques generative architecture by evaluating its scientific rhetoric and disjunction from actual scientific theory and practice. Based on the author's years of field research in architecture studios and biological labs, this rare, field-building book does no less than definitively, unsparingly explain the role of the natural sciences within contemporary architecture.

Metamaterials represent a new emerging innovative field of research which has shown rapid acceleration over the last couple of years. In this handbook, we present the richness of the field of metamaterials in its widest sense, describing artificial media with sub-wavelength structure for control over wave propagation in four volumes.Volume 1 focuses on the fundamentals of electromagnetic metamaterials in all their richness, including metasurfaces and hyperbolic metamaterials. Volume 2 widens the picture to include elastic, acoustic, and seismic systems, whereas Volume 3 presents nonlinear and active photonic metamaterials. Finally, Volume 4 includes recent progress in the field of nanoplasmonics, used extensively for the tailoring of the unit cell response of photonic metamaterials.In its totality, we hope that this handbook will be useful for a wide spectrum of readers, from students to active researchers in industry, as well as teachers of advanced courses on wave propagation.

Pulitzer Prize FinalistSilver Gavel Award Finalist“A sobering history of how American communities and institutions have relied on torture in various forms since before the United States was founded.”—Los Angeles Times“That Americans as a people and a nation-state are violent is indisputable. That we are also torturers, domestically and internationally, is not so well established. The myth that we are not torturers will persist, but Civilizing Torture will remain a powerful antidote in confronting it.”—Lawrence Wilkerson, former Chief of Staff to Secretary of State Colin Powell“Remarkable…A searing analysis of America's past that helps make sense of its bewildering present.”—David Garland, author of Peculiar InstitutionMost Americans believe that a civilized state does not torture, but that belief has repeatedly been challenged in moments of crisis at home and abroad. From the Indian wars to Vietnam, from police interrogation to the War on Terror, US institutions have proven far more amenable to torture than the nation's commitment to liberty would suggest.Civilizing Torture traces the history of debates about the efficacy of torture and reveals a recurring struggle to decide what limits to impose on the power of the state. At a time of escalating rhetoric aimed at cleansing the nation of the undeserving and an erosion of limits on military power, the debate over torture remains critical and unresolved.

In this book, the synthesis and applications of recent nanomaterials are discussed and reviewed in detail. The scope of the book covers from nanocrystals and their self-assembly, synthesis and applications of optically active porphyrin particles, and synthesis and applications of carbon nanodots. Depending on the categories of the materials, detailed driving forces to self-assembly of the cluster or arrays are discussed. Finally, major applications of each category nanomaterial are discussed.Nanomaterials discussed in this book are important building blocks for nanoelectronic and nanophotonic device fabrications. Methods to synthesize and functionalize them are crucial to enable their applications in these areas. This book provides readers with detailed description and discussions on synthesis and functionalization of recent optically active nanomaterials. This book is an important tool for researchers in the nanomaterial field. It will be also a great reference for college students to master overall knowledge in the field.

3D printing (or, more correctly, additive manufacturing) is the general term for those software-driven technologies that create physical objects by successive layering of materials. Due to recent advances in the quality of objects produced and to lower processing costs, the increasing dispersion and availability of these technologies have major implications not only for manufacturers and distributors but also for users and consumers, raising unprecedented challenges for intellectual property protection and enforcement. This is the first and only book to discuss 3D printing technology from a multidisciplinary perspective that encompasses law, economics, engineering, technology, and policy. Originating in a collaborative study spearheaded by the Hanken School of Economics, the Aalto University and the University of Helsinki in Finland and engaging an international consortium of legal, design and production engineering experts, with substantial contributions from industrial partners, the book fully exposes and examines the fundamental questions related to the nexus of intellectual property law, emerging technologies, 3D printing, business innovation, and policy issues. Twenty-five legal, technical, and business experts contribute sixteen peer-reviewed chapters, each focusing on a specific area, that collectively evaluate the tensions created by 3D printing technology in the context of the global economy. The topics covered include: • current and future business models for 3D printing applications; • intellectual property rights in 3D printing; • essential patents and technical standards in additive manufacturing; • patent and bioprinting; • private use and 3D printing; • copyright licences on the user-generated content (UGC) in 3D printing; • copyright implications of 3D scanning; and • non-traditional trademark infringement in the 3D printing context. Specific industrial applications – including aeronautics, automotive industries, construction equipment, toy and jewellery making, medical devices, tissue engineering, and regenerative medicine – are all touched upon in the course of analyses. In a legal context, the central focus is on the technology's implications for US and European intellectual property law, anchored in a comparison of relevant laws and cases in several legal systems. This work is a matchless resource for patent, copyright, and trademark attorneys and other corporate counsel, innovation economists, industrial designers and engineers, and academics and policymakers concerned with this complex topic.

Body centric wireless networking and communications is an emerging 4G technology for short (1-5 m) and very short (below 1 m) range communications systems, used to connect devices worn on (or in) the body, or between two people in close proximity. It has great potential for applications in healthcare delivery, entertainment, surveillance, and emergency services. This book brings together contributions from a multidisciplinary team of researchers in the field of wireless and mobile communications, signal processing and medical measurements to present the underlying theory, implementation challenges and applications of this exciting new technology.

This book provides readers with an integrative overview of the latest research and developments in the broad field of biomedical engineering. Each of the chapters offers a timely review written by leading biomedical engineers and aims at showing how the convergence of scientific and engineering fields with medicine has created a new basis for practically solving problems concerning human health, wellbeing and disease. While some of the latest frontiers of biomedicine, such as neuroscience and regenerative medicine, are becoming increasingly dependent on new ideas and tools from other disciplines, the paradigm shift caused by technological innovations in the fields of information science, nanotechnology, and robotics is opening new opportunities in healthcare, besides dramatically changing the ways we actually practice science. At the same time, a new generation of engineers, fluent in many different scientific “languages,” is creating entirely new fields of research that approach the “old” questions from a new and holistic angle. The book reports on the scientific revolutions in the field of biomedicine by describing the latest technologies and findings developed at the interface between science and engineering. It addresses students, fellows, and faculty and industry investigators searching for new challenges in the broad biomedical engineering fields.

Biomaterials Nanoarchitectonics, written from the perspectives of authors form NIMS and other researchers worldwide, provides readers with an explanation of the theory and techniques of nanoarchitectonics, exploring its applications in biomedical fields, including regenerative medicine, drug delivery, and diagnostic and treatment systems based on pathogenic mechanisms. The book also explains the use of nanomaterials that enable'materials therapy', in which the materials themselves elicit a sustainable, curative effect from living tissue. - Authored by the team that coined the term nanoarchitectonics, who explain their approach to the design of smart/functional nanomaterials and their applications in the biomedical arena - Explores how materials designed and produced with nanoarchitectonics methods can be used to enhance the natural regenerative power of the human body - Enables scientists and researchers to gain a deeper understanding of the specific challenges of materials design at the nanoscale

This book concentrates on the emerging area of the utilization of (solar) photon energy for catalyzing useful chemical reactions (also called artificial photosynthesis) including water splitting, CO2 reduction, selective epoxidation, selective alcohol oxidation, coupling reactions, etc. The chapters in this book cover topics ranging from materials design at nanometer scale to nanomaterials synthesis to photocatalytically chemical conversion. This book can serve as a useful reference for those new to this field of research or already engaged in it, from graduate students to postdoctoral fellows and practicing researchers.

Molecular bioelectronics is a field in strong evolution at the frontier of life and materials sciences. The term is utilized in a broad context to emphasize a unique blend of electronics and biotechnology which is seen as the best way to achieve many objectives of industrial and scientific relevance, including biomolecular engineering, bioelectronic devices, materials and sensors capable of optimal hardware efficiency and intelligence and molecular miniaturization.

The field of pore scale phenomena is now emerging as one of the frontiers of science and many engineering disciplines. Transport phenomena in the subsurface of the earth play key roles in the energy and environmental domains. For example, the shale gas and oil boom is revolutionizing the world's energy portfolio. Pore scale phenomena from the nanoscale to mesoscale dominate the extraction of these resources. Similarly in the environmental domain, pore storage and pore-scale physics affect the availability of water resources and protecting its quality. Water flow and vapor transport in the pores near the land surface is critical to understanding soil water evaporation in the context of local and global hydrologic cycles affecting climate and climate change.Pore scale phenomena similarly play critical roles in the domain of materials science and biology. For example, many energy devices and membrane technologies are controlled by the physical and chemical properties of the pores. Identifying and analyzing the properties of these pores has emerged as a frontier of characterization science.This book provides, for the first time, a comprehensive overview of the fascinating interrelationship between engineering and science. The authors and contributors are recognized experts from the faculty of the Colorado School of Mines, Northwestern and Stanford. This book will appeal to earth and environmental scientists, materials scientists, physicists and chemists.

Tissue engineering aims to develop biological substitutes that restore, maintain, or improve damaged tissue and organ functionality. To date, numerous stem cells and biomaterials have been explored for a variety of tissue and organ regeneration. The challenge for existing stem cell-based techniques is that current therapies lack controlled environm

Stem Cell Nanoengineering reviews the applications of nanotechnology in the fields of stem cells, tissue engineering, and regenerative medicine. Topics addressed include various types of stem cells, underlying principles of nanobiotechnology, the making of nano-scaffolds, nano tissue engineering, applications of nanotechnology in stem cell tracking and molecular imaging, nano-devices, as well as stem cell nano-engineering from bench to bedside. Written by renowned experts in their respective fields, chapters describe and explore a wide variety of topics in stem cell nanoengineering, making the book a valuable resource for both researchers and clinicians in biomedical and bioengineering fields.

Selected, peer reviewed papers from the International Conference on Nanoscience & Nanotechnology 2013 (NANO-SciTech 2013), March 1-4, 2013, Shah Alam, Selangor, Malaysia

Selected, peer reviewed papers from the 4th International Conference of Bionic Engineering (ICBE'13), August 13–16, 2013, Nanjing, China

This book brings together recent developments in the areas of MEMS tribology, novel lubricants and coatings for nanotechnological applications, biomimetics in tribology and fundamentals of micro/nano-tribology. Tribology plays important roles in the functioning and durability of machines at small length scales because of the problems associated with strong surface adhesion, friction, wear etc. Recently, a number of studies have been conducted to understand tribological phenomena at nano/micro scales and many new tribological solutions for MEMS have been proposed.

Selected, peer reviewed papers from the 2012 3rd International Conference on Manufacturing Science and Technology (ICMST 2012), August 18-19, 2012, New Delhi, India

Selected papers from the 2nd International Conference on Advanced Design and Manufacturing Engineering (ADME 2012), August 16-18, 2012, Taiyuan, China

Defined as, “The science about the development of an embryo from the fertilization of the ovum to the fetus stage,” embryology has been a mainstay at universities throughout the world for many years. Throughout the last century, embryology became overshadowed by experimental-based genetics and cell biology, transforming the field into developmental biology, which replaced embryology in Biology departments in many universities. Major contributions in this young century in the fields of molecular biology, biochemistry and genomics were integrated with both embryology and developmental biology to provide an understanding of the molecular portrait of a “development cell.” That new integrated approach is known as stem-cell biology; it is an understanding of the embryology and development together at the molecular level using engineering, imaging and cell culture principles, and it is at the heart of this seminal book. Stem Cells and Regenerative Medicine: From Molecular Embryology to Tissue Engineering is completely devoted to the basic developmental, cellular and molecular biological aspects of stem cells as well as their clinical applications in tissue engineering and regenerative medicine. It focuses on the basic biology of embryonic and cancer cells plus their key involvement in self-renewal, muscle repair, epigenetic processes, and therapeutic applications. In addition, it covers other key relevant topics such as nuclear reprogramming induced pluripotency and stem cell culture techniques using novel biomaterials. A thorough introduction to stem-cell biology, this reference is aimed at graduate students, post-docs, and professors as well as executives and scientists in biotech and pharmaceutical companies.

Conjugation of synthetic materials with cell-responsive biologically-active molecules, in addition to providing structural support and release of biomolecules in the regenerating region, can provide the signaling factors required to initiate the cascade of cell migration, adhesion, differentiation, maturation, growth factor modulation, maintenance of matrix integrity, and tissue morphogenesis. Nanoparticles conjugated with ligands that preferentially interact with cell surface receptors in the tumor environment have the potential to drastically improve bioavailability, selectivity and residence time of the chemotherapeutic agent in the tumor microenvironment, while limiting their peripheral toxicity. Multivalent presentation of tumor-associated antigens on a targeted delivery system containing T and B cell epitopes can result in strong, long-lasting, self-adjuvant immunity against cancer and other diseases in vaccination. These examples demonstrate that cell-responsive conjugate biomaterials have profoundly impacted the medical field.This book is divided into three sections. In the first section, synthesis and characterization, conformation, structure-activity, self-assembly, and host response of conjugate hybrid biomaterials are covered. The second section is dedicated to the applications of conjugate biomaterials in drug delivery and vaccination while the last section is devoted to tissue engineering applications including cell adhesion, control of the stem cell niche, cartilage regeneration, neural and vascular tissue engineering, and dynamic cell culture systems for functionalized biomaterials.There is no doubt that biologically-responsive conjugate biomaterials play a key role in the design of biologics and medical devices, and this pioneering reference book provides a comprehensive review on synthesis, characterization, structure-activity, 3D assembly/fabrication, host response and the emerging applications of conjugate hybrid biomaterials.

Supported with 140 illustrations, the volume exhaustively covers the micro- and nano-system technologies involved in developing cell-based bioengineering applications. You get full details on efforts to engineer the soluble and insoluble cell microenvironments, including the latest advances in microfluidic devices, surface patterning, 3D scaffolds, and techniques for engineering cellular mechanical properties and topography.

Gain thorough understanding of the science and engineering behind today?s most advanced life sciences automation devices, systems, and technologies and their applications in biotechnology, pharmacology, and healthcare with this cutting-edge book. This comprehensive interdisciplinary resource details state-of-the-art design, modeling, and fabrication techniques for automation tools and demonstrates how they can be most effectively integrated in powerful medium-scale to large-scale automation systems to solve specific problems and challenges in the biological sciences.

4M 2006 - Second International Conference on Multi-Material Micro Manufacture covers the latest state-of-the-art research results from leading European researchers in advanced micro technologies for batch processing of metals, polymers, and ceramics, and the development of new production platforms for micro systems-based products. These contributions are from leading authors at a platform endorsed and funded by the European Union R&D community, as well as leading universities, and independent research and corporate organizations. - Contains authoritative papers that reflect the latest developments in micro technologies and micro systems-based products

The United States has built a carceral state that is unprecedented among Western countries and in US history. Nearly one in 50 people, excluding children and the elderly, is incarcerated today, a rate unsurpassed anywhere else in the world. What are some of the main political forces that explain this unprecedented reliance on mass imprisonment? Throughout American history, crime and punishment have been central features of American political development. This 2006 book examines the development of four key movements that mediated the construction of the carceral state in important ways: the victims'movement, the women's movement, the prisoners'rights movement, and opponents of the death penalty. This book argues that punitive penal policies were forged by particular social movements and interest groups within the constraints of larger institutional structures and historical developments that distinguish the United States from other Western countries.