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Climate change has more impact on the world than just rising temperatures and extreme weather events. It also impacts the intricate interactions between organisms, including pests, pathogens, and other biotic factors, which are critical components of the balance maintained in nature. This new book delves into the intricate relationship between climate change and the interplay of biotic factors, shedding light on the molecular mechanisms underlying these interactions.

This book provides a summary of the state of the art of all facets of debris-flow science and practice and is designed to be a comprehensive technical reference for practitioners and a state-of-the-art research overview for scientists. It is richly illustrated with equations, graphs, photos, and tables. The book allows students, practitioners, and regulators to get a sense of the current state of the art in this science. Currently, there are 2 to 3 papers published every week on some aspects of debris-flow science. This creates a bewildering amount of literature that cannot be captured by a single individual. This book provides a comprehensive overview of all facets to date, including initial hazard assessments, detailed quantitative risk assessments, debris-flow warning systems, debris-flow mitigation structure designs, and failures of mitigation works, as well as new topics such as climate change effects on debris flows.

This fourth edition offers a practical guide to endovascular treatment of cerebrovascular disease and provides a comprehensive reference for the related neurovascular anatomy and the various disorders that affect the vascular system. Chapters cover fundamental principles underlying cerebral and spinal angiography; interventional techniques, devices, and practice guidelines; and commonly encountered cerebrovascular disorders for which interventional and endovascular methods are appropriateBuilding on the previous edition, the text is presented similarly in style and scope to emphasize accessibility and ease of reading. All chapters are fully updated to include more recent data, and obsolete products and techniques are replaced with the most current technology. Some key updates include:A greater emphasis on the use of radial artery access for the discussed endovascular techniques.The associations of COVID-19 with ischemic stroke and the implicationsof providing care for cerebrovascular patients during a pandemic.An extensive update to the acute ischemic stroke chapter with new references and format to more closely follow the format of other chapters in that section.Expansion of the pediatric sections of disease chapters, including discussions of genetic associations with disease. This is an ideal guide for clinicians and trainees in neurology, neurosurgery and neuroradiology, as well as practicing clinicians in related fields caring for patients with cerebrovascular disease.

Forming and Machining of Polymers, Ceramics, and Composites targets the two important manufacturing processes where plastic deformation is involved to give the required shape and size to the raw material. The main goal of the book is to represent the recent developments in the field of forming and machining of different non-metals, especially polymers, composites, and ceramics. Special focus is on the advancement of these processes to manufacture components from these non-metals. Presents exclusive material dedicated to forming and machining of non-metals, that is, polymers, ceramics, and composites Provides comprehensive coverage of all important topics related to non-metals processing Covers basics and current research in the field of forming and machining of non-metals Focuses on sustainability interventions and intelligent manufacturing techniques for quality and productivity in forming and machining of non-metals Discusses conventional and non-conventional machining and microfabrication aspects for fabrication and processing of non-metals This book is aimed at graduate students and researchers in materials processing and machine design.

This fully updated second edition provides an introduction to geotechnical earthquake engineering for first-year graduate students in geotechnical or earthquake engineering graduate programs with a level of detail that will also be useful for more advanced students as well as researchers and practitioners. It begins with an introduction to seismology and earthquake ground motions, then presents seismic hazard analysis and performance-based earthquake engineering (PBEE) principles. Dynamic soil properties pertinent to earthquake engineering applications are examined, both to facilitate understanding of soil response to seismic loads and to describe their practical measurement as part of site characterization. These topics are followed by site response and its analysis and soil–structure interaction. Ground failure in the form of soil liquefaction, cyclic softening, surface fault rupture, and seismically induced landslides are also addressed, and the book closes with a chapter on soil improvement and hazard mitigation. The first edition has been widely used around the world by geotechnical engineers as well as many seismologists and structural engineers.The main text of this book and the four appendices: Cover fundamental concepts in applied seismology, geotechnical engineering, and structural dynamics Contain numerous references for further reading, allowing for detailed exploration of background or more advanced material Present worked example problems that illustrate the application of key concepts emphasized in the text Include chapter summaries that emphasize the most important points Present concepts of performance-based earthquake engineering with an emphasis on uncertainty and the types of probabilistic analyses needed to implement PBEE in practice Present a broad, interdisciplinary narrative, drawing from the fields of seismology, geotechnical engineering, and structural engineering to facilitate holistic understanding of how geotechnical earthquake engineering is applied in seismic hazard and risk analyses and in seismic design

This book provides a detailed introduction to the characteristics of cerebral aneurysms and the current treatment methods. Cerebral aneurysms are not rare, and they have a high disability and mortality rate. Most patients are unaware that they have a cerebral aneurysm, with the most common being cerebral hemorrhage. The diagnosis and treatment of cerebral aneurysms have been ongoing for more than 100 years. We have achieved excellent results, but there are still many things that we do not know. An increasing number of unruptured cerebral aneurysms are accidentally discovered during neuroimaging examinations. The greatest risk of cerebral aneurysm is the risk of rupture. Due to the extremely high mortality rate, once these aneurysms are detected, systematic treatment is necessary. The earlier a patient is referred to a neurosurgeon or interventional neuroradiologist, the better the outcome will be compared to the patient experiencing rupture. The decision to treat is multifactorial.

Pepper Virome: Molecular Biology, Diagnostics and Management presents detailed information about the plant viruses that infect pepper worldwide, providing crucial insights for both the scientific community and producers. Understanding the nature of the viruses, their transmission methods and possible sources of resistance in order to minimize the yield losses as well as to reduce the spread of these viruses to new locations or countries is of global importance.Pepper is an important commodity worldwide. It is cultivated for both fresh produce and for processing industry as a spice. However, various diseases affect pepper production and cause significant yield losses in pepper yield. The increasing outbreaks of virus species infecting　Capsicum　spp. have become a major problem for growers. A combination of factors, including expansion and intensification of pepper cultivation, availability of volunteer hosts, abundance of insect vectors and climate change have all contributed to the issue. Pepper Virome provides in-depth information on both the viruses infecting peppers, and eco-friendly management measures to decrease the rate of spread of viruses. Addressing the need for increased international collaboration and exchange of pepper germplasm, these insights will also facilitate the selection and breeding for improved　Capsicum　spp. adapted to local conditions and uses. - Focuses on symptomatology, transmission, and epidemiology of pepper viruses - Reveals the impact on host, yield, and virus-vector interactions - Evaluates management strategies against viruses and how they have evolved

The book presents advancements in computational intelligence in perception with healthcare applications. Besides, the concepts, theory, and applications in various domains of healthcare systems including decision making in healthcare management, disease diagnosis, and electronic health records will be presented in a lucid manner. To achieve these objectives, both theoretical advances and its applications to healthcare problems will be stressed upon. This has been done to make the edited book more flexible and to stimulate further research interest in topics. The book is divided into four sections such as theoretical foundation of computational intelligence techniques, computational intelligence in analyzing health data, computational intelligence in electronic health record (EHR), and computational intelligence in ethical issues in health care.

The Encyclopedia of Electrochemical Power Sources, Second Edition, is a comprehensive seven-volume set that serves as a vital interdisciplinary reference for those working with batteries, fuel cells, electrolyzers, supercapacitors, and photo-electrochemical cells. With an increased focus on the environmental and economic impacts of electrochemical power sources, this work not only consolidates extensive coverage of the field but also serves as a gateway to the latest literature for professionals and students alike. The field of electrochemical power sources has experienced significant growth and development since the first edition was published in 2009. This is reflected in the exponential growth of the battery market, the improvement of many conventional systems, and the introduction of new systems and technologies. This completely revised second edition captures these advancements, providing updates on all scientific, technical, and economic developments over the past decade. Thematically arranged, this edition delves into crucial areas such as batteries, fuel cells, electrolyzers, supercapacitors, and photo-electrochemical cells. It explores challenges and advancements in electrode and electrolyte materials, structural design, optimization, application of novel materials, and performance analysis. This comprehensive resource, with its focus on the future of electrochemical power sources, is an essential tool for navigating this rapidly evolving field. - Covers the main types of power sources, including their operating principles, systems, materials, and applications - Serves as a primary source of information for electrochemists, materials scientists, energy technologists, and engineers - Incorporates 365 articles, with timely coverage of environmental and sustainability aspects - Arranged thematically to facilitate easy navigation of topics and easy exploration of the field across its key branches - Follows a consistent structure and features elements such as key objective boxes, summaries, figures, references, and cross-references etc., to help students, faculty, and professionals alike

This book explores the ongoing debate between shallow and deep learning in the field of machine learning. It provides a comprehensive survey of machine learning methods, from shallow learning to deep learning, and examines their applications across various domains. Shallow Learning vs Deep Learning: A Practical Guide for Machine Learning Solutions emphasizes that the choice of a machine learning approach should be informed by the specific characteristics of the dataset, the operational environment, and the unique requirements of each application, rather than being influenced by prevailing trends. In each chapter, the book delves into different application areas, such as engineering, real-world scenarios, social applications, image processing, biomedical applications, anomaly detection, natural language processing, speech recognition, recommendation systems, autonomous systems, and smart grid applications. By comparing and contrasting the effectiveness of shallow and deep learning in these areas, the book provides a framework for thoughtful selection and application of machine learning strategies. This guide is designed for researchers, practitioners, and students who seek to deepen their understanding of when and how to apply different machine learning techniques effectively. Through comparative studies and detailed analyses, readers will gain valuable insights to make informed decisions in their respective fields.

As the global population continues to grow, the depletion of Earth's resources poses a significant challenge in ensuring food security for current and future generations. This book addresses this pressing issue by presenting innovative strategies and methods to reduce food loss, enhance production, identify alternative ingredients, and digitize the food system. It explores topics like the circular economy, cellular agriculture, artificial intelligence in food production, and novel sources of ingredients like microalgae and insects. Engineers play a pivotal role in translating ideas into tangible products and services that enhance human lives. Innovations in Engineering and Food Science is a comprehensive guide that explores the latest advancements, technologies, challenges, and solutions in the domains of engineering and food science. This book delves into the integration of cutting-edge technologies such as Artificial Intelligence (AI), Blockchain, Internet of Things (IoT), Quantum Computing, and Virtual and Augmented Reality, showcasing their potential to revolutionize the engineering landscape. With a focus on emerging technologies and practical solutions, Innovations in Engineering and Food Science serves as a valuable resource for researchers, students, academicians, and professionals in these fields. It provides a platform for expanding theoretical knowledge and offers insights into the applicability of various methods. This book empowers readers to adopt and test the proposed approaches in their own research, ultimately fostering advancements and contributing to the progress of engineering and food science. Featuring contributions from experts in the field, this edited volume covers a wide range of topics, including soft computing, image processing, sensors, smart cities, unmanned aerial vehicles, cybersecurity, cloud computing, nanotechnology in food safety, and innovative approaches for sustainable food production.

This book provides a broad, evidence based resource for all clinicians who encounter challenging patients suffering from TMDs. Common causes of craniofacial and myofascial pain of the head and neck, TMD treatment paradigms, and associated symptoms are explained. Background information on TMJ Anatomy, TMD Epidemiology and Pathology is given and advanced topics like therapeutic target and movement disorders and TMD are discussed. All chapters follow a uniform outline and quality of material.This well-referenced book draws attention to the lack of appreciation and understanding of craniofacial pain diagnosis and intervention, and it equips readers to optimize basic treatment of patients with TMD.

Frozen shoulder is a condition most often characterized by severe shoulder pain and functional restriction of the shoulder motion in multiple directions. About 4% of the general population will develop a frozen shoulder, with numbers rising to 59% in patients with diabetes mellitus. It curiously only develops between the age of 40 and 60 years, affects more women than men and seems to be more common in patients with sedentary jobs. Disease duration varies between 1 and 3 years and consequently has a large impact on the health and economic well-being of individuals and society. Frozen Shoulder: Present and Future provides readers with insight into one of the most mysterious diseases of the human body. One day you're perfectly fine, and the next day you're hit by unbearable shoulder pain, which sets in motion many sleepless nights: welcome to the mysterious world of frozen shoulder. - Presents evidence-based treatment of frozen shoulder - Includes a section on future perspectives and ongoing research - Written by international renowned experts

The International Conference on Sustainable Materials, Structures and IoT (SMSI-2024) was organized by Department of Civil Engineering, Indira Gandhi Institute of Technology Sarang, India. The practical problems associated with various engineering in many developing countries including India and developed countries are different and complex. Therefore, researchers and agencies have been working to tackle these challenges and to identify implementable solutions for various transportation engineering related problems as per prevailing conditions. As a recurring event with nationwide participation, SMSI-2024 converged experts, researchers, practitioners, industry professionals around the world to share and deliberate on their work, offering profound insights into emerging technological trends. This conference invited papers related to various themes under the umbrella of engineering.

As the global community confronts challenges in energy, environment, health, agriculture, industry, and construction, the significance of sustainable materials becomes paramount. The looming specter of resource depletion necessitates a paradigm shift, urging researchers and engineers to anticipate future needs and forge materials that align with evolving requirements. Next Generation Materials for Sustainable Engineering underscores the urgency of conserving resources and provides a blueprint for achieving this through judicious and sustainable use. From polymers to alloys, nanocomposites to biomaterials, this book traverses the expansive landscape of materials, deciphering their structures and properties with an eye toward sustainability. The relentless pursuit of innovation in synthesis protocols takes center stage, unveiling pathways to creating novel materials. Through meticulous characterization and insightful analyses, the book unravels the mysteries of these materials, offering a panoramic view of their applications. The chapters dedicated to specific material applications, such as spintronics, nanowires, phase change materials, and nanocomposites, offer a detailed panorama of the latest advancements. This book bridges the gap between theoretical understanding and practical applications by exploring materials for renewable energy, electronic devices, artificial photosynthesis, lithium-sulfur batteries, supercapacitors, and biomedical applications. The book serves as a beacon for academicians, researchers, and material scientists, guiding them through state-of-the-art developments, emerging trends, and challenges in material science and engineering. It enriches their knowledge base and charts a roadmap for the promotion of research in this critical domain. The fusion of advances in materials with the ethos of sustainability is a central theme, interpreting how research and development can be integrated with practical applications.

Webtoons—a form of comic that are typically published digitally in chapter form—are the latest manifestation of the Korean Wave of popular culture that has increasingly caught on across the globe, especially among youth. Originally distributed via the Internet, they are now increasingly distributed through smartphones to ravenous readers in Korea and around the world. The rise of webtoons has fundamentally altered the Korean cultural market due to the growth of transmedia storytelling—the flow of a story from the original text to various other media platforms, such as films, television, and digital games—and the convergence of cultural content and digital technologies. Fans can enjoy this content anytime and anywhere, either purely as webtoons or as webtoon-based big-screen culture. Understanding Korean Webtoon Culture analyzes webtoons through the lens of emerging digital cultures and discusses relevant cultural perspectives by combining two different, yet connected approaches, political economy and cultural studies. The book demonstrates the dynamics between structural forces and textual engagement in global media flows, and it illuminates snack-culture and binge-reading as two new forms of digital culture that webtoon platforms capitalize on to capture people's shifting media consumption.

With the growing concern for the environment and the rising price of crude oil, there is increasing demand for non-petroleum-based polymers from renewable resources. Biopolymer films have been regarded as potential replacements for synthetic films in food packaging due to a strong marketing trend toward environmentally friendly materials. Biopolymer-based films and coatings display good barrier properties, flexibility, transparency, economic profitability, and environmental compatibility. Therefore, they have successfully been used for packaging various food products. Biopolymer-Based Films and Coatings: Trends and Challenges elaborates on the recent methods and ingredients for making biodegradable films and coatings, as well as the current requirements for food security and environmental issues. This book also explores films and coatings prepared with essential oils, antimicrobial substances, and bioactive components that make up this active packaging. Films and coating chapters are based on biopolymers used to prepare films and coatings, that is, carbohydrates, lipids, proteins, and so on. This book provides a platform for researchers and industrialists on the basic and advanced concepts of films and coatings. Key Features Provides a comprehensive analysis of recent findings on biopolymers (carbohydrate-, protein-, and lipid-) based films and coatings Contains a wealth of new information on the properties, functionality, and applications of films and coatings Presents possible active and functional components and ingredients for developing films and coatings. Guides start-up researchers on where to start the latest research work in packaging It has been estimated that the global production of bioplastics is set to hike from ~2.11 in 2020 to ~2.87 million tonnes in 2025. Further, the demand for fresh, ready-to-eat, or semi-finished foods is increasing, and the need to maintain food safety and quality further exacerbates the challenges in the supply chain, especially with the globalization of food trade and the use of centralized processing facilities for food distribution. It is an urgent requirement to increase shelf life and reduce food product loss. Considering the great market demand for biodegradable material-based packaging systems, this book comes at an opportune time to enable researchers and food scientists to develop suitable solutions considering the sustainability and economic feasibility of the process.

This comprehensive textbook, published in collaboration with ESSKA, now in a revised and updated second edition, covers all major shoulder problems and related arthroscopic treatments. Introductory sections on basic science and the principles of shoulder arthroscopy provide essential information with the aim of enhancing understanding of a wide range of key issues. Shoulder conditions and their treatments are then described according to a learning pathway that will allow readers to improve their knowledge and skills in shoulder arthroscopy, from simple, standardized techniques to more complex and advanced procedures. The new edition includes additional chapters and offers attractive recent surgical solutions to challenging shoulder conditions, such as severe bone loss in shoulder instability and massive and irreparable rotator cuff tears. All chapters are written by expert arthroscopic surgeons who present decision-making algorithms for diagnosis and treatment, provide step-by-step instructions on arthroscopic techniques, identify pitfalls, and describe their personal tips and pearls. A dedicated section on outcomes measurements and experimental models explains the principles of outcome research on the topics addressed in the book.

Hailed as the wonder material of the 21st century, graphene presents a wide range of possibilities in terms of its technological and industrial uses. This reference text provides a comprehensive review of the recent advances in graphene-based research and technology. The book combines the necessary background and theory alongside a broad spectrum of cutting-edge applications of graphene and its types. Recent advances, including electronic, photonic, optoelectronic and sensing applications, and membranes and coatings, are presented in detail. Special chapters are devoted to the most contemporary attributes of graphene, mainly its metamaterial, magnetic and non-linear properties. The book concludes with a discussion of future prospects of graphene-based research. Aimed at both advanced researchers and those new to the field, the book is suitable for research scholars, scientists, teachers and the wider academic community. Key Features Provides a comprehensive review of recent advances in graphene-based research and technology Covers developments such as magnetism in graphene, graphene metamaterials and membranes and coatings Combines the necessary background, theory, and cutting-edge applications of graphene and its types Explores the latest synthesis techniques including CVD and the novel high yield exfoliation method Covers electronic, photonic, optoelectronic and sensing applications in detail

This book provides a holistic compilation on applications of carbon nanostructures, especially in advanced healthcare applications. It comprises chapters on utility of diverse multifunctional nanocarriers in drug delivery and biomedical applications, especially emphasizing on the synthesis and characterizations of nanosystems along with surface engineering approaches used for active targeting of the drugs. Moreover, the chapters also include the recent updates on the applications of the nanocarriers to fulfill the needs of various healthcare systems.

Transfer learning is one of the most important technologies in the era of artificial intelligence and deep learning. It seeks to leverage existing knowledge by transferring it to another, new domain. Over the years, a number of relevant topics have attracted the interest of the research and application community: transfer learning, pre-training and fine-tuning, domain adaptation, domain generalization, and meta-learning. This book offers a comprehensive tutorial on an overview of transfer learning, introducing new researchers in this area to both classic and more recent algorithms. Most importantly, it takes a “student's” perspective to introduce all the concepts, theories, algorithms, and applications, allowing readers to quickly and easily enter this area. Accompanying the book, detailed code implementations are provided to better illustrate the core ideas of several important algorithms, presenting good examples for practice.

Introduction to Proteomics presents an overview of proteomics, including a discussion of the field's fundamental ideas, how to use various technologies and instruments, and examples of applications in human health and illness. This textbook provides new students and researchers with an easy-to-grasp, comprehensive review and knowledge of the concepts, guidelines, and especially the difficult instrumentation procedures in proteomics.

The book Organic Light Emitting Diode (OLED) Toward Smart Lighting and Displays Technologies, edited by Laxman Singh, Rituraj Dubey, and Prof. R. N. Rai, strives to address the multiple aspects of OLEDs and their applications in developing smart lightings and displays. OLEDs have been used in almost all kinds of digital displays like those of mobile phones, laptops, tablets, phablets, TVs, etc., due to their outstanding features, including superior color quality, low cost, wide viewing angle, easy fabrication, mercury-free manufacture, tenability, stretchability, flexibility, etc. Investigations related to the synthesis of new organic materials and fabrication techniques have inspired us to write this book, which will fulfil the desire and thirst of OLEDs-based researchers.Features Nanolithographic techniques used and the challenges involved Printing technology for fabrication Designing of hybrid perovskites Stretchable and flexible materials used Metal–dielectric composites and efficiency of organic semiconductor via molecular doping for OLEDs applications Organic small molecule materials and display technologies involved New generation of organic materials with respect to photophysical approach Mixed valence π-conjugated coordination polymers used Electroluminescent polymer used Blue fluorescent and phosphorescent organic materials used In comparison to other books available related to similar topics, this book aims at those audiences who are looking for a single source for a comprehensive understanding of strategies and their challenges with respect to material fabrication of OLEDs. This book covers the pace and productivity at a uniform level in each chapter with respect to the audiences, from doctoral student to postdoctoral researchers or from postdoctoral researchers to multidisciplinary field researchers with a background in physics, chemistry, materials science, and engineering, who are already working with organic materials and their applications.

“The Use Of Mathematical Structures: Modelling Real Phenomena” is an edited book consisting of 16 contemporaneous open-access articles that are devoted to the mathematical modelling of natural phenomena. To summarize, this book is about the use of applied mathematics and mathematical analysis in the context of its applications to real-world problems. It includes a selection of real-world problems in fluid dynamics, mechanical engineering, biology, and biochemistry. The last chapters include the mathematical modelling of the COVID-19 virus. The intended audience of this book is undergraduate and graduate students, as well as junior researchers. The reader must have a good knowledge of ordinary differential equations, boundary value problems, fractional calculus, stability theory, and wavelets in order to fully understand the real-world problems and their mathematical modelling included in this book.

Photoactive organic molecules such as luminophores and photoswitches react upon irradiation with light by emitting light of a specific wavelength or a conformational change, respectively. Organic thermally activated delayed fluorescence (TADF) materials are highly efficient luminophores that readily find application in organic light-emitting diodes (OLEDs) or as dyes in cellular imaging. Three aromatic, heterocyclic electron-accepting systems for novel red luminophores with TADF properties were investigated based on dibenzo[a,c]phenazine, pyrrolo[3,4-f]isoindole-1,3,5,6(2H,6H)-tetraone and 1H‑pyrrolo[3,4‑b]quinoxaline-1,3(2H)-dione. Light can also be used to trigger conformational changes and azobenzenes are one of the most prominent examples. An optical control over ion channels can be achieved by attaching azobenzenes to ligands. The investigation of the synthesis of azobenzenes with modified substitution patterns was conducted, among them a push-pull system designed to bring an electron-donating and electron-accepting moiety into spatial proximity upon photoswitching.

Combustion agents for solid fuel propellants and explosives have gained widespread interest in recent years. Their high gravimetric heat of combustion enhances the performance of modern energetic materials. Borohydride compounds have proved to be excellent candidates in this application. High-energy Combustion Agents of Borohydrides covers the most recent developments in the advanced combustion agents of borohydrides. Experimental studies covering the synthesis and characterisation of borohydrides are examined, as well as the interactions between borohydride and propellant ingredients. The properties of BHN/nano Al composites are discussed, as is the effect of borohydrides on the properties of fuel-rich solid propellants. The book concludes with a summary of the prospective development of high-energy combustion agents in solid propellants and explosives, and looks into the future development of military applications. Authored by renowned experts in the field, this book will appeal to researchers in academia and industry seeking a better understanding of how to improve the ignition and combustion performance of propellants and explosives.

This handbook comprehensively reviews different nanomaterials and modern electrochemical approaches used in the point-of-care analysis of biomolecules. It describes the importance, significance, and application of various kinds of smart nanomaterials and their integration with modern electrochemical techniques for the point-of-care diagnosis of biologically important biomolecules. The interaction between bio-systems and nanomaterials have been discussed in this book using advanced electrochemical methods and characterizing techniques. It describes the combination of classical and modern methodologies for the synthesis of metal nanoparticles/nanoclusters and modern electrochemical techniques for the early-stage detection and point-of-care diagnosis of cancer and other infectious disease such as SARS, influenza, tuberculosis (TB), and hepatitis. Finally, the book provides an accessible and readable summary of the use of nanomaterial for understanding the electrochemical reaction taking place at nano-bio interfaces in electrochemical biomolecular detection and analysis. The book bridges the gap and strengthens the relationship between electrochemists, material scientists, and biomolecular scientists who are directly or indirectly associated with the field of such point-of-care diagnostics. ​

Organic Reaction Mechanisms 2019, the 55th annual volume in this highly successful and unique series, surveys research on organic reaction mechanisms described in the available literature dated 2019. The following classes of organic reaction mechanisms are comprehensively reviewed: Reaction of Aldehydes and Ketones and their Derivatives Reactions of Carboxylic, Phosphoric, and Sulfonic Acids and their Derivatives Oxidation and Reduction Carbenes and Nitrenes Nucleophilic Aromatic Substitution Electrophilic Aromatic Substitution Carbocations Nucleophilic Aliphatic Substitution Carbanions and Electrophilic Aliphatic Substitution Elimination Reactions Polar Addition Reactions Cycloaddition Reactions Molecular Rearrangements Radicals An experienced team of authors compile these reviews every year, so that the reader can rely on a continuing quality of selection and presentation.

Role of Nutrigenomics in Modern-day Healthcare and Drug Discovery presents novel insights into how these tools can be applied in the study of nutrient-gene interaction for the management of certain disease conditions without using synthetic drugs or other treatments that come with side effects. Divided into three parts, Part I presents chapters that give background information of the subject while laying a framework for other chapters to follow. Part II presents chapters that discuss the role of nutrigenomics in healthcare, while Part III presents chapters that discuss the role of nutrigenomics in modern day drug discovery. Written by a global team of experts from key institutions around the world, this book is useful for drug developers, medicinal chemists, public health scientists, molecular biologists, biochemists, toxicologists and food scientists. - Provides readers with background information on the role of nutrigenomics in healthcare, with a focus on emerging topics in nutrigenetics and nutrigenomics - Presents chapters that discusses the role of nutrigenomics in the modern day drug discovery for the treatment and management of diseases - Includes a wide array of definitions, methods, summaries, figures and tables to aid readers with understanding and application

This book examines deep learning-based approaches in the field of cancer diagnostics, as well as pre-processing techniques, which are essential to cancer diagnostics. Topics include introduction to current applications of deep learning in cancer diagnostics, pre-processing of cancer data using deep learning, review of deep learning techniques in oncology, overview of advanced deep learning techniques in cancer diagnostics, prediction of cancer susceptibility using deep learning techniques, prediction of cancer reoccurrence using deep learning techniques, deep learning techniques to predict the grading of human cancer, different human cancer detection using deep learning techniques, prediction of cancer survival using deep learning techniques, complexity in the use of deep learning in cancer diagnostics, and challenges and future scopes of deep learning techniques in oncology.

This volume contains the proceedings of the 12th International Conference on Geosynthetics (12 ICG), held in Roma, Italy, 17-21 September 2023. About 750 Authors - Academics, Researchers, Students, Practitioners, Contractors and Manufacturers – contributed to the peer-reviewed papers of this volume, which includes the Giroud lecture, the Bathurst lecture, the Rowe lecture, four keynote lectures and 296 technical papers. The content of these proceedings illustrates the sustainable use of geosynthetics in a variety of innovative as well as consolidated applications. After the sustainability implications in the correct use of geosynthetics, the ability to overcome the natural events effects, often related to the climate change, and to adequately afford the human activities (as the increase of pollution) forced to refer to a new keyword: Resiliency. The 12 ICG intends to become the base for the next step, hence the conference theme is'Geosynthetics, Leading the Way to a Resilient Planet'. The conference topics, through general and parallel sessions, invited presentations and keynote lectures, address the most recent developments in geosynthetic engineering, and stimulate fruitful technical and scientific interaction among academicians, professionals, manufacturers, students. The 12 ICG proceedings contain a wealth of information that could be useful for researchers, practitioners and all those working in the broad, innovative and dynamic field of geosynthetics.

Medical imaging provides medical professionals the unique ability to investigate and diagnose injuries and illnesses without being intrusive. With the surge of technological advancement in recent years, the practice of medical imaging has only been improved through these technologies and procedures. It is essential to examine these innovations in medical imaging to implement and improve the practice around the world. The Research Anthology on Improving Medical Imaging Techniques for Analysis and Intervention investigates and presents the recent innovations, procedures, and technologies implemented in medical imaging. Covering topics such as automatic detection, simulation in medical education, and neural networks, this major reference work is an excellent resource for radiologists, medical professionals, hospital administrators, medical educators and students, librarians, researchers, and academicians.

Advances in Semiconductor Technologies Discover the broad sweep of semiconductor technologies in this uniquely curated resource Semiconductor technologies and innovations have been the backbone of numerous different fields: electronics, online commerce, the information and communication industry, and the defense industry. For over fifty years, silicon technology and CMOS scaling have been the central focus and primary driver of innovation in the semiconductor industry. Traditional CMOS scaling has approached some fundamental limits, and as a result, the pace of scientific research and discovery for novel semiconductor technologies is increasing with a focus on novel materials, devices, designs, architectures, and computer paradigms. In particular, new computing paradigms and systems—such as quantum computing, artificial intelligence, and Internet of Things—have the potential to unlock unprecedented power and application space. Advances in Semiconductor Technologies provides a comprehensive overview of selected semiconductor technologies and the most up-to-date research topics, looking in particular at mainstream developments in current industry research and development, from emerging materials and devices, to new computing paradigms and applications. This full-coverage volume gives the reader valuable insights into state-of-the-art advances currently being fabricated, a wide range of novel applications currently under investigation, and a glance into the future with emerging technologies in development. Advances in Semiconductor Technologies readers will also find: A comprehensive approach that ensures a thorough understanding of state-of-the-art technologies currently being fabricated Treatments on all aspects of semiconductor technologies, including materials, devices, manufacturing, modeling, design, architecture, and applications Articles written by an impressive team of international academics and industry insiders that provide unique insights into a wide range of topics Advances in Semiconductor Technologies is a useful, time-saving reference for electrical engineers working in industry and research, who are looking to stay abreast of rapidly advancing developments in semiconductor electronics, as well as academics in the field and government policy advisors.

The eleventh edition of Social Inequality: Forms, Causes, and Consequences is an introduction to the study of social inequality. Fully updated statistics and examples convey the pervasiveness and extent of social inequality in the United States. The authors use an intersectional perspective to show how inequality occurs, how it affects all of us, and what is being done about it.With more resources and supplementary examples, exercises, and applications embedded throughout to aid students'learning and visualization of important concepts, the book provides a rich theoretical treatment to address the current state of inequality. In line with current affairs, the authors have expanded the content to include: An intersectional approach throughout the chapters A stronger emphasis on the connections between poverty, wealth, and income inequality New case studies on the opioid epidemic, COVID-19, the lead poisoning crisis, and climate change A new focus on the rise of right-wing movements. With additional content and classroom extensions available online for instructors, Social Inequality remains an ideal and invaluable overview of the subject and provides undergraduate students with a robust understanding of social inequality from a sociological perspective.

This book provides an overview of recent advances in technologies for water treatment processes, such as green technology, nano-adsorbents, photocatalysts, advanced oxidation, membranes separation and sustainable technologies. Advances in membrane technology and fabrication process is presented in detail. Latest approaches like microbial treatment, electro chemical and solar energy-based treatment techniques were presented. Also, the use of sustainable and energy efficient approaches were discussed.· The book presents the negative impact of inorganic and organic pollutants on the natural environment and human health.It describes and discussing the advanced membrane technologies, novel green adsorbents, microbial treatment techniques, electro chemical and solar based removal techniquesIt also compares the most effective methods of removing toxic contaminants from water solutions with the use of sustainable and energy efficient approachesIt also presents the life cycle assessment of emerging technologies in industrial wastewater treatment and desalination as well as presents the benchmarking of energy efficiency during treatment process

This book will attempt to provide an account of knowledge on biomass available for biomass-based biorefineries. Its focuses on understanding the recalcitrance of biomass and how it limits the overall conversion efficiency. It also gives an insight what are different conventional approaches available for pretreatment and hydrolysis of the biomass. The chapters deals with highlights how enzymes can be a powerhouse and play pioneering roles in biomass valorization. The book will also throw light on how technical aspects of thermochemical conversion strategies such as pyrolysis, gasification, organosolv methods for the generation of value-added materials such as high-quality bio-oil, biochars, and biobased chemicals. These high-value compounds can be put to widespread application in biofuel, biocatalyst, waste bioremediation (heavy metal removal), air purification and effluent treatment applications. The book will provide literature on the limitations of already existing technologies and provide prospects of each technology. This book is of interest to teachers, researchers, bioenergy scientists, capacity builders, and policymakers. Also, the book serves as additional reading material for undergraduate and graduate students of energy studies, chemical engineering, biotechnology, and environmental sciences. National and international energy scientists and policymakers will also find this to be a useful read.

Making sense of nature in one of the world's most contested borderlands. According to Chinese government reports, hundreds of plague-infected rodents fell from the skies over Gannan county on an April night in 1952. Chinese scientists determined that these flying voles were not native to the region, but were vectors of germ warfare, dispatched over the border by agents of imperialism. Mastery of biology had become a way to claim political mastery over a remote frontier. Beginning with this bizarre incident from the Korean War, Knowing Manchuria places the creation of knowledge about nature at the center of our understanding of a little-known but historically important Asian landscape. At the intersection of China, Russia, Korea, and Mongolia, Manchuria is known as a site of war and environmental extremes, where projects of political control intersected with projects designed to make sense of Manchuria's multiple environments. Covering more than 500,000 square miles, Manchuria's landscapes include temperate rainforests, deserts, prairies, cultivated plains, wetlands, and Siberian taiga. With analysis spanning the seventeenth century to the present day, Ruth Rogaski reveals how an array of historical actors—Chinese poets, Manchu shamans, Russian botanists, Korean mathematicians, Japanese bacteriologists, American paleontologists, and indigenous hunters—made sense of the Manchurian frontier. She uncovers how natural knowledge, and thus the nature of Manchuria itself, changed over time, from a sacred “land where the dragon arose” to a global epicenter of contagious disease; from a tragic “wasteland” to an abundant granary that nurtured the hope of a nation.

With the start of 2020, the wrath of pandemic challenged the scientific community to develop more advanced drug delivery approaches for biomedical applications, endowing conventional drugs with additional therapeutic benefits and minimum side effects. Although significant advancements have been done in the field of drug delivery, there is a need to focus towards strategizing novel and improved drug delivery systems that should be convenient and cost-effective to the patients, and simultaneously they should also provide financial benefits to pharmaceutical companies. Controlled drug delivery technology offers ample opportunities and scope for improvising the therapeutic efficacy of drugs via optimizing thedrug release rate and time. For this endeavour, smart nanomaterials have served as remarkable candidates for biomedical applications, owing to their ground-breaking properties and design. The development of such nanomaterials requires a broad knowledge related to their physio-chemical properties, molecular structure, mechanisms by which the nanomaterials interact with the cells, and methods by which drugs are released at the site of action. This knowledge must also be allied with the knowledge of signaling crosstalk mechanisms that are modulated by the nanomaterial-drugs composite. It can be anticipated that these emerging drug delivery technologies can facilitate the world to successfully encounter such pandemic outbursts in the future in a cost-effective and time-effective manner. The chapters in this book deal with the advanced technologies and approaches that can benefit advanced students, researchers, and industry experts in developing smart and intelligent nanomaterials for future biomedical applications, and development, manufacturing, and commercialization for controlled and targeted drug delivery.

This book covers the intersections between neurointervention and neurology, neurointervention and neurosurgery, and neurointervention and other specialties. It fills the gap in the literature by placing specific emphasis on appropriate patient selection, preparation, and post-procedural management. Concise and comprehensive, this text covers the increasingly important aspects of the neurointerventionalist profession, as it has moved away from a purely technical role to a focus on clinical care. In addition, the most rapidly expanding area of neurointervention, ischemic stroke, is thoroughly examined in this text, where other texts on this subject fail. It is also meant as a reference for non-neurointerventionalists who may desire to learn more about how their patients can benefit from the therapeutic or adjunctive techniques that the neurointerventionalist can provide. Neurointervention in the Medical Specialties, Second Edition is an essential guide written for neurointerventional specialists from all backgrounds, both in practice and in training

Soil organic matter (SOM) is the primary determinant of soil functionality. Soil organic carbon (SOC) accounts for 50% of the SOM content, accompanied by nitrogen, phosphorus, and a range of macro and micro elements. As a dynamic component, SOM is a source of numerous ecosystem services critical to human well-being and nature conservancy. Important among these goods and services generated by SOM include moderation of climate as a source or sink of atmospheric CO2 and other greenhouse gases, storage and purification of water, a source of energy and habitat for biota (macro, meso, and micro-organisms), a medium for plant growth, cycling of elements (N, P, S, etc.), and generation of net primary productivity (NPP). The quality and quantity of NPP has direct impacts on the food and nutritional security of the growing and increasingly affluent human population.Soils of agroecosystems are depleted of their SOC reserves in comparison with those of natural ecosystems. The magnitude of depletion depends on land use and the type and severity of degradation. Soils prone to accelerated erosion can be strongly depleted of their SOC reserves, especially those in the surface layer. Therefore, conservation through restorative land use and adoption of recommended management practices to create a positive soil-ecosystem carbon budget can increase carbon stock and soil health.This volume of Advances in Soil Sciences aims to accomplish the following: Present impacts of land use and soil management on SOC dynamics Discuss effects of SOC levels on agronomic productivity and use efficiency of inputs Detail potential of soil management on the rate and cumulative amount of carbon sequestration in relation to land use and soil/crop management Deliberate the cause-effect relationship between SOC content and provisioning of some ecosystem services Relate soil organic carbon stock to soil properties and processes Establish the relationship between soil organic carbon stock with land and climate Identify controls of making soil organic carbon stock as a source or sink of CO2 Connect soil organic carbon and carbon sequestration for climate mitigation and adaptation

This book offers a comprehensive overview of the development and application of microfluidics and biosensors in cancer research, in particular, their applications in cancer modeling and theranostics.Over the last decades, considerable effort has been made to develop new technologies to improve the diagnosis and treatment of cancer. Microfluidics has proven to be a powerful tool for manipulating biological fluids with high precision and efficiency and has already been adopted by the pharmaceutical and biotechnology industries. With recent technological advances, particularly biosensors, microfluidic devices have increased their usefulness and importance in oncology and cancer research.The aim of this book is to bring together in a single volume all the knowledge and expertise required for the development and application of microfluidic systems and biosensors in cancer modeling and theranostics. It begins with a detailed introduction to the fundamental aspects of tumor biology, cancer biomarkers, biosensors and microfluidics. With this knowledge in mind, the following sections highlight important advances in developing and applying biosensors and microfluidic devices in cancer research at universities and in the industry. Strategies for identifying and evaluating potent disease biomarkers and developing biosensors and microfluidic devices for their detection are discussed in detail. Finally, the transfer of these technologies into the clinical environment for the diagnosis and treatment of cancer patients will be highlighted. By combining the recent advances made in the development and application of microfluidics and biosensors in cancer research in academia and clinics, this book will be useful literature for readers from a variety of backgrounds. It offers new visions of how this technology can influence daily life in hospitals and companies, improving research methodologies and the prognosis of cancer patients.

In the automotive industry, the need to reduce vehicle weight has given rise to extensive research efforts to develop aluminum and magnesium alloys for structural car body parts. In aerospace, the move toward composite airframe structures urged an increased use of formable titanium alloys. In steel research, there are ongoing efforts to design novel damage-controlled forming processes for a new generation of efficient and reliable lightweight steel components. All these materials, and more, constitute today's research mission for lightweight structures. They provide a fertile materials science research field aiming to achieve a better understanding of the interplay between industrial processing, microstructure development, and the resulting material properties. The Handbook of Research on Advancements in the Processing, Characterization, and Application of Lightweight Materials provides the recent advancements in the lightweight mat materials processing, manufacturing, and characterization. This book identifies the need for modern tools and techniques for designing lightweight materials and addresses multidisciplinary approaches for applying their use. Covering topics such as numerical optimization, fatigue characterization, and process evaluation, this text is an essential resource for materials engineers, manufacturers, practitioners, engineers, academicians, chief research officers, researchers, students, and vice presidents of research in government, industry, and academia.

Diverse Quasiparticle Properties of Emerging Materials: First-Principles Simulations thoroughly explores the rich and unique quasiparticle properties of emergent materials through a VASP-based theoretical framework. Evaluations and analyses are conducted on the crystal symmetries, electronic energy spectra/wave functions, spatial charge densities, van Hove singularities, magnetic moments, spin configurations, optical absorption structures with/without excitonic effects, quantum transports, and atomic coherent oscillations.Key Features Illustrates various quasiparticle phenomena, mainly covering orbital hybridizations and spin-up/spin-down configurations Mainly focuses on electrons and holes, in which their methods and techniques could be generalized to other quasiparticles, such as phonons and photons Considers such emerging materials as zigzag nanotubes, nanoribbons, germanene, plumbene, bismuth chalcogenide insulators Includes a section on applications of these materials This book is aimed at professionals and researchers in materials science, physics, and physical chemistry, as well as upper-level students in these fields.

This insightful volume opens new horizons for exploring modern therapeutic entities and emerging targets for combating the deadly disease of cancer. The authors provide a review of cancer along with descriptions of its molecular level mechanisms and emphasize the role of promising new therapies, including herbal therapies, that can be utilized for the treatment of metastatic diseases. The chapters look at specific approaches that have been researched and developed and that have almost reached the standardization stage, such as intracellular mechanisms, particularly phosphoprotein-enriched astrocytes and transthyretin proteins; CXCR4; autophagy-inhibiting drugs; spatiotemporal genetic analysis; tyrosine kinase inhibitors; and more. Also considered are advances in diagnostic systems like intra vital microscopy and molecular imaging.

Deep eutectic solvents represent the newest addition among all other non-conventional and alternate solvent systems. Deep Eutectic Solvent Fund Emerging Applications provides detailed insights on these neoteric solvents, their synthesis methods, types, physicochemical properties, and sustainable applications in emerging scientific areas. The book follows a mechanistic approach on understanding the role of DESs as sustainable media for CO2 capture, biomass pretreatment, as catalysts, as reaction media for material synthesis, cross coupling reactions, templates for drug delivery, etc. The book offers a springboard for encouraging vital discussions and inspiring further innovations in the field of environmentally benign eutectic solvent systems. - Provides a detailed account of development on DESs with special focus on hydrophilic /hydrophobic DESs - Describes experimental and theoretical outlook on the physical and chemical properties of DESs - Discusses the toxicity profiling of DESs and their importance in designing biocatalytic routes - Includes DESs in emerging areas - pharmaceuticals, drug discovery, functional materials and membrane science - Covers use of DESs in CO2 capture, biomass transformations, organic reactions, etc.

Innovative and Emerging Technologies in the Bio-marine Food Sector: Applications, Regulations, and Prospects presents the use of technologies and recent advances in the emerging marine food industry. Written by renowned scientists in the field, the book focuses primarily on the principles of application and the main technological developments achieved in recent years. It includes technological design, equipment and applications of these technologies in multiple processes. Extraction, preservation, microbiology and processing of food are extensively covered in the wide context of marine food products, including fish, crustaceans, seafood processing waste, seaweed, microalgae and other derived by-products. This is an interdisciplinary resource that highlights the potential of technology for multiple purposes in the marine food industry as these technological approaches represent a future alternative to develop more efficient industrial processes. Researchers and scientists in the areas of food microbiology, food chemistry, new product development, food processing, food technology, bio-process engineers in marine based industries and scientists in marine related areas will all find this a novel resource. - Presents novel innovative technologies in the Bio-marine food sector, including principles, equipment, advantages, disadvantages, and future technological prospects - Explores multi-purpose uses of technologies for extraction, functional food generation, food preservation, food microbiology and food processing - Provides industrial applications tailored for the marine biological market to foster new innovative applications and regulatory requirements

Community health is an emerging and growing discipline of public health and it focuses on the physical, social, and mental well-being of the people of specific districts. This interdisciplinary field brings together aspects of health care, economics, environment, and people interaction. This handbook is a comprehensive reference on public health for higher education students, scholars, practitioners, and policymakers of health care. There are five key thematic sections in the book: perspectives in public health; community health in practise; planning, built, and social environment and community health; digital and mobile health; and, towards sustainable health in the community. Each theme explores the leading research and trends. This book aims to help achieve the shared goal of healthier communities and quality of life for the residents. This collaborative work should be a very useful handbook to health professionals and government bodies in the planning of initiatives to improve population health, prevent chronic diseases, control infectious diseases and outbreaks, and prepare for natural disasters. This handbook integrates research and practise of public health in the community.

This book aims to provide reader an overview of clinical applications of contrast-enhanced ultrasound in hepatic neoplasms diagnosis. Ultrasound images and pathological results of different hepatic neoplasms are introduced in the chapters, including benign liver tumors, malignant liver tumors, hepatic carcinoma, intrahepatic cholangiocarcinoma, rare liver benign and malignant neoplasms, regenerative nodules, inflammatory pseudotumor, parasite liver lesions, and hepatitis peliosis, etc. The combination of ultrasound findings with final histopathological results then discover the potential mechanical of contrast enhancement changes. With the development of ultrasound technology and widely application of ultrasound contrast agents (USCA) in recent decades, contrast-specific imaging modalities have been developed in combination with USCA and a low mechanical index (MI), allowing continuous real-time grey scale imaging. The updated contrast-specific software for liver diseases and hepatic tumors diagnosis has also been described described in detail. With high-resolution contrast ultrasound images during arterial phase, portal venous phase and late phase, author wants to show the whole dynamic wash-in and wash-out process of the different focal liver lesions.This book is an invaluable resource for radiologists, hepatologists and oncologists in their everyday clinical practice.

This book presents high-quality research papers presented at the International Conference on Soft Computing for Intelligent Systems (SCIS 2020), held during 18–20 December 2020 at University Institute of Engineering and Technology, Kurukshetra University, Kurukshetra, Haryana, India. The book encompasses all branches of artificial intelligence, computational sciences and machine learning which is based on computation at some level such as AI-based Internet of things, sensor networks, robotics, intelligent diabetic retinopathy, intelligent cancer genes analysis using computer vision, evolutionary algorithms, fuzzy systems, medical automatic identification intelligence system and applications in agriculture, health care, smart grid and instrumentation systems. The book is helpful for educators, researchers and developers working in the area of recent advances and upcoming technologies utilizing computational sciences in signal processing, imaging, computing, instrumentation, artificial intelligence and their applications.

This book provides a comprehensive and up-to-date guide to the AMOLED technologies and applications which have become industry standard in a range of devices, from small mobile displays to large televisions. Unlike other books on the topic, which cover the fundamentals, materials, processing, and manufacturing of OLEDs, this one-stop book discusses the core components, such as TFT backplanes, OLED materials and devices, and driving schematics together in one volume with chapters written by experts from leading international companies in the field of OLED materials and OLED TVs. It also examines emerging areas, such as micro-LEDs, displays using quantum dots, and AR & VR displays. Presenting the latest research trends as well as the basic principles of each topic, this book is intended for undergraduate and postgraduate students taking display-related courses, new researchers, and engineers in related fields.