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The fifth addition of this classic text that focuses on the diabetic foot continues the tradition of the previous four editions. More specifically, it includes contributions from a distinguished panel of clinicians and researchers, who have either participated in previous editions or are new, who provide up-to-date information on the pathophysiology and management of diabetic foot ulceration. As with the previous editions, it is divided into three sections: the first part focuses on clinical features and diagnosis; the second on pathophysiology; and the third on the management of diabetic foot problems. The main emphasis of the clinical part is on the multidisciplinary approach that has been mainly developed by the world-renowned Joslin-Beth Israel Deaconess Foot Center, which pioneered the management of diabetic lower extremity problems. Also like previous editions, the author panel includes diabetologists, podiatrists, vascular surgeons, infectious disease specialists,orthotists, plastic and orthopedic surgeons, the majority of whom work at the Joslin-Beth Israel Deaconess Foot Center. In addition, the fifth edition not only describes the state-of-the-art current methods in clinical practice but also includes a thorough update of all research progress during the last five years. This updated edition of this timely text will be of significant value to all physicians and researchers with interest in a comprehensive understanding of the diabetic foot.

The 3rd edition of this book provides a comprehensive, fully updated, overview of diabetic neuropathy. Divided into three sections, chapters are authored by leading scientists and physicians in the world. The 1st section, Clinical Features and Diagnosis, discusses the clinical examination of diabetic neuropathy as well as the use of objective point-of-care devices in diagnosis. The 2nd section, Pathophysiology, reviews the pathophysiology of diabetic neuropathy and potential therapeutic targets. The last section, Clinical Consequences and Treatments, reviews the management of diabetic neuropathies as well as the latest treatment options for various neuropathies. Diabetic Neuropathy, Third Edition, will be of interest to clinicians, practitioners, and researchers, as well as students, residents, and fellows.

In the fourth edition of this gold-standard title, a distinguished panel of experts provides a thorough update of the significant improvements in our understanding of diabetic foot physiology and its clinical management. Divided into three sections, the first part focuses on clinical features and diagnosis; the second on pathophysiology; and the third on the management of diabetic foot problems. In addition to updating all previous chapters, several new contributions have been added, reflecting advances in our understanding of the causes of diabetic foot ulcers and efforts to develop new and more effective therapies. The authors, many practicing at the famous Joslin-Beth Israel Deaconess Foot Center, again illuminate the successful new multidisciplinary approach now clearly required for successful treatment of the diabetic foot. Drawing on the experiences of diabetologists, podiatrists, vascular surgeons, infectious disease specialists, orthotists, plastic and orthopedic surgeons, The Diabetic Foot: Medical and Surgical Management, 4th Edition expertly describes standard techniques and current methods derived from the most recent data. This updated edition will be of significant value to all physicians and researchers with interest in a state-of-the-art understanding of the diabetic foot.

Now in a fully revised and updated second edition, written and editing by leading experts in the field, this comprehensive and practical text brings together the latest guidelines and recommendations on the benefits of exercise and physical activity in the management of diabetes and its complications, providing both the researcher and practitioner with evidence-based information that is both theoretically and clinically useful. Part one sets the stage by discussing the epidemiology and prevention of type 2 diabetes and the metabolic syndrome. The physiological effects of exercise in type 2 diabetes are covered in part two, covering molecular mechanisms, adiposity, sex differences, cardiovascular consequences and musculoskeletal changes. Part three addresses practical issues that are essential in order to safely engage patients with diabetes in exercise-related research protocols and clinical programs, including DPP and LOOK Ahead, nutrition, behavioral changes, and guidelines for exercise testing. The final section examines special considerations for exercise in people with diabetes, such as those with neuropathy, cardiac issues and peripheral artery disease. Taken together, Diabetes and Exercise, Second Edition brings together the latest information and thought leaders in the field to create a unique and useful text for all clinicians, researchers and therapists working to integrate physical activity into their management strategies for the increasing number of diabetic patients.

Leading medical specialists critically review for the general practitioner the latest techniques for the clinical management of diabetic neuropathy. These authoritative contributors focus on the practical aspects of diabetic neuropathy and describe in detail the treatments that are currently available or expected to become available in the near future. They also include concise discussions of the causes of diabetic neuropathy and highlight the relatively unknown features of neuropathy that can significantly impact a patient's life. Comprehensive, up-to-date bibliographies at the end of each chapter provide an opportunity for the interested physician to gain a more detailed picture of a particular topic. This book offers family physicians, internists, endocrinologists, podiatrists, cardiologists, neurologists, and gastroenterologists an authoritative practical guide and a vital day-to-day reference source for the management of their neuropathic diabetic patients.

In The Diabetic Foot: Medical and Surgical Management, 3rd Edition, a distinguished panel of clinicians provides a thorough update of the significant improvements in knowledge surrounding the pathogenesis of diabetic foot problems, as well as the optimal healthcare treatment for this debilitating condition. The authors, many practicing at the famous Joslin-Beth Israel Deaconess Foot Center, again illuminate the successful new multidisciplinary approach now clearly required for the successful treatment of diabetic foot. Drawing on the experiences of diabetologists, podiatrists, vascular surgeons, infectious disease specialists, orthotists, plastic and orthopedic surgeons, this invaluable third edition, so timely given the continued rise of diabetes and its complications, clearly describes established techniques known to be effective. This updated edition blends new knowledge with the time-tested principles of diabetic foot management and will be of significant value to all physicians and researchers with an interest in a state-of-the-art understanding of diabetic foot.

Diabetes is a major public health problem in the United States. This collection, Diabetes and Exercise, discusses the extent of the problem of diabetes and sedentary lifestyle and presents a compelling rationale for the importance of increased physical activity and exercise in persons with diabetes. The concept of exercise as medicine has a strong but underappreciated scientific basis for the prevention and treatment of diabetes. Diabetes and Exercise, compiled by a team of experts in the field, focuses on both the physiological and practical aspects of the beneficial effects of exercise. This thorough collaboration provides the why's and how's to implementing the physical activity and exercise changes so important in diabetes prevention and disease management.

In this newly updated, second edition, leading medical specialists critically review for the general practitioner the latest techniques for the clinical management of diabetic neuropathy. These authoritative contributors focus on the practical aspects of diabetic neuropathy and describe in detail the treatments that are currently available or expected to become available in the near future. They also include concise discussions of the pathogenesis of diabetic neuropathy and highlight the relatively unknown features of neuropathy that can significantly impact a patient's life. Comprehensive, up-to-date bibliographies at the end of each chapter provide an opportunity for the interested physician to gain a more detailed picture of a particular topic.

The cause of diabetes mellitus is metabolic in origin. However, its major clinical manifestations, which result in most of the morbidity and mortality, are a result of its vascular pathology. In fact, the American Heart Association has recently stated that, “from the point of view of cardiovascular medicine, it may be appropriate to say, diabetes is a cardiovascular disease” (1). But diabetic vascular disease is not limited to just the macrovasculature. Diabetes mellitus also affects the microcirculation with devastating results, including nephropathy, neuropathy, and retinopathy. Diabetic nephropathy is the leading cause of end-stage renal disease in the United States, while diabetic retinopathy is the leading cause of new-onset blindness in working-age Americans. The importance of this text on Diabetes and Cardiovascular Disease is evident by the magnitude of the population affected by diabetes mellitus. Over 10 million Americans have been diagnosed with diabetes mellitus, while another 5 million remain undiagnosed. The impact from a public health perspective is huge and increasing. As the population of the United States grows older, more sedentary, and obese, the risk of developing diabetes and its complications will increase. Epidemiological studies have identified diabetes mellitus as a major independent risk factor for cardiovascular disease. Over 65% of patients with diabetes mellitus die from a cardiovascular cause. The prognosis of patients with diabetes mellitus who develop overt clinical cardiovascular disease is much worse than those cardiovascular patients free of diabetes mellitus.

In The Diabetic Foot: Medical and Surgical Management, a distinguished panel of clinicians-many practicing at the famous Joslin-Beth Israel Deaconess Foot Center-illuminate the successful new multidisciplinary approach now clearly required for the successful treatment of this medical problem. Drawing on the experiences of diabetologists, podiatrists, vascular surgeons, infectious disease specialists, orthotists, plastic and orthopedic surgeons, the book clearly describes established techniques known to be effective. Also highlighted are the many emerging treatments that will affect diabetic foot care in the years ahead, including a new understanding of wound-healing pathophysiology and the recent introduction of growth factors and living skin equivalents.

With over ten million diagnosed patients and another five million undiagnosed, diabetes mellitus and its complications-cardiovascular disease, nephropathy, neuropathy, and retinopathy-is a major public health problem that will assume epidemic proportions as the population grows older. In Diabetes and Cardiovascular Disease, Michael T. Johnstone, md, and Aristidis Veves, md, dsc, have assembled a panel of seasoned clinicians and expert scientists to comprehensively review both the clinical and scientific aspects of diabetic cardiovascular disease. The contributors thoroughly discuss the mechanisms and risk factors of diabetes in relation to hypertension, dyslipidemia, thrombosis, atherosclerosis, coronary artery disease, and congestive heart failure. Their review includes a full examination of the epidemiology, mechanisms, methods of assessment, and treatment of the disease at the macrovascular level, and a discussion of its microvascular effects, including retinopathy, nephropathy, neuropathy, and compromised microcirculation in the diabetic foot. Each chapter covers its topics in great detail and is accompanied by extensive references. Comprehensive and up-to-date, Diabetes and Cardiovascular Disease offers not only practicing physicians the day-to-day practical knowledge needed to treat patients effectively, but also clinical scientists a deeper understanding for developing novel therapies for this devastating illness.

This third edition of the book offers an up-to-date review of Diabetes Mellitus with a focus on both Micro- and Macrovascular Disease. The text includes a review of the basic concepts of : Diabetes and Vascular Disease, including Endothelial Dysfunction; The Effect of Insulin on the Vascular System; The Mechanism of Atherosclerosis in Diabetes Mellitus and the Role of Inflammation on the Vascular Tree; and The Role of the Renin-Angiotensin-Aldosteronism on Diabetes Mellitus. Chapters will discuss the Genetics of Type 2 Diabetes Mellitus as well as the Metabolic Syndrome. Other chapters discuss the Risk Factors of Diabetes and Vascular Disease, including Hypertension; Dyslipidemia; and Thrombosis. The book also reviews Microcirculation; Diabetic Nephropathy; Diabetic Retinopathy; as well as the Epidemiology, Diagnosis, and Treatment of Peripheral Vascular Disease; Diabetes and Coronary Artery Disease; Diabetes and Percutaneous Interventions; Diabetes and Cardiac Surgery; and Diabetes and Heart Failure. Chapters conclude with a review of the present-day Treatment of the Diabetic Patient. Diabetes and Cardiovascular Disease, 3rd Edition, offers practicing physicians a cutting-edge scientific and clinical review of diabetic cardiovascular disease, providing both a deeper understanding of its pathology and all the day-to-day practical knowledge needed to treat patients effectively.