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Forecasting and Analytics with the Augmented Dynamic Adaptive Model (ADAM) focuses on a time series model in Single Source of Error state space form, called “ADAM” (Augmented Dynamic Adaptive Model). The book demonstrates a holistic view to forecasting and time series analysis using dynamic models, explaining how a variety of instruments can be used to solve real life problems. At the moment, there is no other tool in R or Python that would be able to model both intermittent and regular demand, would support both ETS and ARIMA, work with explanatory variables, be able to deal with multiple seasonalities (e.g. for hourly demand data) and have a support for automatic selection of orders, components and variables and provide tools for diagnostics and further improvement of the estimated model. ADAM can do all of that in one and the same framework. Given the rising interest in forecasting, ADAM, being able to do all those things, is a useful tool for data scientists, business analysts and machine learning experts who work with time series, as well as any researchers working in the area of dynamic models.Key Features:• It covers basics of forecasting,• It discusses ETS and ARIMA models,• It has chapters on extensions of ETS and ARIMA, including how to use explanatory variables and how to capture multiple frequencies,• It discusses intermittent demand and scale models for ETS, ARIMA and regression,• It covers diagnostics tools for ADAM and how to produce forecasts with it,• It does all of that with examples in R.

All the Essentials to Start Using Adaptive Designs in No TimeCompared to traditional clinical trial designs, adaptive designs often lead to increased success rates in drug development at reduced costs and time. Introductory Adaptive Trial Designs: A Practical Guide with R motivates newcomers to quickly and easily grasp the essence of adaptive desig

Combining the two statistical techniques of network sampling and adaptive sampling, this book illustrates the advantages of using them in tandem to effectively capture sparsely located elements in unknown pockets. It shows how network sampling is a reliable guide in capturing inaccessible entities through linked auxiliaries. The text also explores

Get Up to Speed on Many Types of Adaptive DesignsSince the publication of the first edition, there have been remarkable advances in the methodology and application of adaptive trials. Incorporating many of these new developments, Adaptive Design Theory and Implementation Using SAS and R, Second Edition offers a detailed framework to understand the

This book aims to provide an overview of some adaptive techniques used in estimating parameters for finite populations where the sampling at any stage depends on the sampling information obtained to date. The sample adapts to new information as it comes in. These methods are especially used for sparse and clustered populations.Written by two acknowledged experts in the field of adaptive sampling.

Adaptive Sampling with Mobile WSN develops algorithms for optimal estimation of environmental parametric fields. With a single mobile sensor, several approaches are presented to solve the problem of where to sample next to maximally and simultaneously reduce uncertainty in the field estimate and uncertainty in the localisation of the mobile sensor while respecting the dynamics of the time-varying field and the mobile sensor. A case study of mapping a forest fire is presented. Multiple static and mobile sensors are considered next, and distributed algorithms for adaptive sampling are developed resulting in the Distributed Federated Kalman Filter. However, with multiple resources a possibility of deadlock arises and a matrix-based discrete-event controller is used to implement a deadlock avoidance policy. Deadlock prevention in the presence of shared and routing resources is also considered. Finally, a simultaneous and adaptive localisation strategy is developed to simultaneously localise static and mobile sensors in the WSN in an adaptive manner. Experimental validation of several of these algorithms is discussed throughout the book.

Adaptive design has become an important tool in modern pharmaceutical research and development. Compared to a classic trial design with static features, an adaptive design allows for the modification of the characteristics of ongoing trials based on cumulative information. Adaptive designs increase the probability of success, reduce costs and the t

ExpDesign Studio facilitates more efficient clinical trial design This book introduces pharmaceutical statisticians, scientists, researchers, and others to ExpDesign Studio software for classical and adaptive designs of clinical trials. It includes the Professional Version 5.0 of ExpDesign Studio software that frees pharmaceutical professionals to focus on drug development and related challenges while the software handles the essential calculations and computations. After a hands-on introduction to the software and an overview of clinical trial designs encompassing numerous variations, Classical and Adaptive Clinical Trial Designs Using ExpDesign Studio: Covers both classical and adaptive clinical trial designs, monitoring, and analyses Explains various classical and adaptive designs including groupsequential, sample-size reestimation, dropping-loser, biomarker-adaptive, and response-adaptive randomization designs Includes instructions for over 100 design methods that have been implemented in ExpDesign Studio and step-by-step demos as well as real-world examples Emphasizes applications, yet covers key mathematical formulations Introduces readers to additional toolkits in ExpDesign Studio that help in designing, monitoring, and analyzing trials, such as the adaptive monitor, graphical calculator, the probability calculator, the confidence interval calculator, and more Presents comprehensive technique notes for sample-size calculation methods, grouped by the number of arms, the trial endpoint, and the analysis basis Written with practitioners in mind, this is an ideal self-study guide for not only statisticians, but also scientists, researchers, and professionals in the pharmaceutical industry, contract research organizations (CROs), and regulatory bodies. It's also a go-to reference for biostatisticians, pharmacokinetic specialists, and principal investigators involved in clinical trials. ERRATUM Classical and Adaptive Clinical Trial Designs Using ExpDesign Studio By Mark Chang The license for the ExpDesign Studio software on the CD included with this book is good for one-year after installation of the software. Prior to the expiration of this period, the software will generate a reminder about renewal for the license. The user should contact CTriSoft International (the owners of ExpDesign Studio) at www.CTriSoft.net or by email at license@ctrisoft.net, about renewal for the license. This should have been made clear in the first printing of this book. We apologize for this error.

Although adaptive design methods are flexible and useful in clinical research, little or no regulatory guidelines are available. One of the first books on the topic, Adaptive Design Methods in Clinical Trials presents the principles and methodologies in adaptive design and analysis that pertain to adaptations made to trial or statistical procedures