Search

Stem Cell Laboratory Techniques: A Guide for Researchers and Students introduces the reader to stem cell culture, handling techniques and versatile applications used by researchers. Sections introduce stem cells, including definitions, types and basic use of stem cells in biomedical science research. The book explains laboratory procedures and techniques ranging from the extraction of stem cells from animals, cell seeding and culture, harvest and maintenance of stem cells, stem cell characterization, accurate recording, quality control, and more. In addition, it guides researchers on topics such as transcriptome analysis, proliferation study analysis, and microphysiological study. Final sections cover useful and recent applications in stem cells, such as gene editing techniques and the preparation of stem cells for in vitro study, as well as stem cell lab design and equipment used in the lab. Lastly, human and animal research ethics are discussed. - Introduces readers to the stem cell culture and moves to handling techniques and versatile applications - Includes coverage of gene editing techniques for stem cells and stem cells for in vitro study - Presents stem cell lab design and equipment used in the lab

Innovation of Food Products in the Halal Supply Chain Worldwide covers the fundamentals and food guidelines of halal food production. Unlike other texts on the halal food market and halal certification, this book promotes halal product innovation by presenting exciting newly developed ingredients that are substitutions of non-halal ingredients with halal alternatives, such as lard substituted with modified vegetable fats, pig with halal goat/beef/camel/fish gelatin/collagen, alternative meat substitute or even additives. Innovations in halal processing technologies cover the latest techniques in halal production and authentication, halal tracking/traceability in halal transport and logistics, a vast area at the end of a supply chain. All chapters are written by acknowledged experts in their field, thus the book brings together the top researchers in this essential topic of importance to a huge percentage of the world's population. - Helps readers understand the advancement of available halal substitutes and replacers - Offers tools to enhances product sustainability and food security through innovation - Fosters innovation in food science with alternative halal ingredients

Atmospheric Nitrogen Deposition in Global Forests: Spatial Variation, Impacts, and Management Implications provides the most comprehensive knowledge on spatial variation and ecological impacts of reactive nitrogen deposition in global forests, as well as forest management options to mitigate the negative impacts. Written and edited by international experts in the field, this book synthesizes recent research developments and insights in monitoring and modeling nitrogen deposition in global forests. The book also assesses ecological impacts of enhanced nitrogen deposition on forest structure and function and responses of forest ecosystems to decreasing nitrogen deposition in regions such as the European Union and North America. Finally, the book reviews indicators and thresholds for nitrogen saturation in global forests and analyzes remediation options to reduce impacts of excess nitrogen deposition. This is an important resource for researchers in forestry and biodiversity conservation, as well as graduate students, policymakers and others who want to understand environmental issues of reactive nitrogen deposition in global forests. - Offers a systematic view of the ecological impacts of enhanced nitrogen deposition - Provides the most comprehensive knowledge on spatial variation and the ecological impacts of reactive nitrogen deposition in global forests - Presents expert research and findings on forest management options to remediate negative impacts

A Multidisciplinary Approach to Managing Swallowing Dysfunction in Older People provides comprehensive coverage on oropharyngeal dysphagia (OD), focusing on older patient phenotypes. The book provides the knowledge needed for translational researchers and professionals to aid in the detection, diagnosis, treatment and management of OD, ultimately improving patient quality of life. OD has been recently considered a geriatric syndrome because of its high prevalence, the increase of life-expectancy and the need to be managed by a multidisciplinary approach. This reference takes a novel approach to OD, covering all aspects as a geriatric syndrome, examining a complicated and multi-level topic in a succinct way. Contents include the most innovative information available in current literature combined with practical applications to improve the diagnosis and treatments of OD as a geriatric syndrome. This is the perfect reference for translational researchers, physicians and healthcare professionals dealing with OD. - Presents full coverage of swallowing impairments in the older population and oropharyngeal dysphagia as a newly defined geriatric syndrome - Explores the latest innovations and research in the field for pathophysiology, diagnosis, ethics, treatment and potential complications - Expertly written chapters by international leading experts in the fields of dysphagia and geriatric medicine are included

Handbook of Food and Feed From Microalgae: Production, Application, Regulation, and Sustainability is a comprehensive resource on all aspects of using microalgae in food and feed. This book covers applied processes, including the utilization of compounds found in microalgae, the development of food products with microalgae biomass in their composition, the use of microalgae in animal nutrition, and associated challenges and recent advances in this field. Written by global leading experts in microalgae, this book begins with the fundamentals of food and feed, including microalgal biodiversity, biogeography, and nutritional purposes. The book continues to describe compounds found within microalgae such as proteins, pigments, and antioxidants. It explains the process incorporation of microalgae into meat, dairy, beverage, and wheat products as well as real-world food applications in finfish aquaculture, mollusk, poultry, and pet feeding. The book concludes by discussing challenges and issues in the field, encompassing bioavailability, bio-accessibility, and how to address safety, regulatory, market, economics, and sustainability concerns. This book is a valuable resource for aquaculturists, food scientists, and advanced undergraduate and graduate students interested in microalgae as a sustainable food and feed ingredient. - Examines current data behind the food and feed production using microalgae-based processes - Analyzes and details the use of microalgae across industries and disciplines - Addresses and offers solutions to safety, market, sustainability, and economic issues

Molecular Biomarkers in Cancer Detection and Monitoring of Therapeutics: Volume Two: Diagnostic and Therapeutic Applications discusses how molecular biomarkers are used to determine predisposition, facilitate detection, improve treatment and offer prevention guidelines for different cancers. It focuses on novel diagnostic techniques based on molecular biomarkers and their impact on treatment, covering different cancer types such as tumors in the nervous system, head and neck, oral and GI tractor, lung, breast, gastric system, leukemia and urogenital tract cancers. For each type, the book discusses the best diagnostic techniques and therapeutic approaches, thus helping readers easily identify the best solution for each case. This is a valuable resource for cancer researchers, oncologists, graduate students and other members of the biomedical field who are interested in the potential of biomarkers in cancer research. - Provides up-to-date information on current molecular biomarkers research for cancer - Presents new diagnostic techniques using biomarkers that can leverage quicker results that can be essential for patient's survivorship - Discusses several novel therapeutics applied to specific cancer types, such as head and neck, oral, GI tract, breast, lung and hepatocellular carcinomas

本書の内容－食生活と生活環境の安全性を求めて 本書は「食品のカビ汚染と危害」(2003)以後に著者自身が集めた食品のカビ72属238種(関連菌を含む)を基にし，培養コロニーのカラー写真，光学顕微鏡によるシャープな形態と走査電子顕微鏡(子嚢胞子)の写真を編集した図版を中心に，それぞれの菌の形態・分布と生態(検出食品の種類・環境・作物やヒトに対する病原性)，発育条件や耐熱性，関連菌との遺伝子解析による系統分類，カビ毒(マイコトキシン)産生を集めたノートなどが書かれています． 本書の魅力は何といっても食品や身の廻りにあるカビが，培養と顕微鏡による細かな観察の結果から，美術デザイナーも驚くほど美しい様々な形をした姿を目にするワクワク感です． 私たちの食生活が安全であるために，食品衛生検査では微生物試験が細菌・カビを対象に行われています．AIに基づく品質管理技術がカビの学名同定に対しても適用されるようになりました．しかし，形態による同定の確認が必要です． 本書ではカビの同定に対応して，遺伝子情報を基にした新分類システムのマニュアルとして食品のカビを検索できるよう，記載内容を充実しました．特に，重要なカビ毒(アフラトキシン)を産生する種があるコウジカビ(Aspergillus)，ムギ赤かび病菌があるフザリウム菌(Fusarium)，低温保管の食品に発生が多く，また黄変米菌やチーズの製造菌があるアオカビ(Penicillium)については，カビ毒の解説とともに既応の分類システムの要約，同定法，クラスター(系統分類群)別検索表を示し，容易に試験できるよう配慮しました． 本書の特徴として，好乾性菌と耐熱性菌について好湿・中湿性菌や易熱性菌と区別できるように記載しました．好乾性菌については項目を別にし，培養検査での省力化を図りました．好乾性菌の対象は長期保存中の穀類，乾燥や糖分・塩分の多い保存食品での好乾性コウジカビの危害が主でしたが，最近では消費者の嗜好が広まり，チョコレート，ドライフルーツ，ブルーベリー，香辛料，カンゾウ，黒糖などの輸入品から様々な好乾性菌を検出しています．特に好乾性の強い菌では，50%蔗糖添加培地での観察が行われています．一方，めん・パスタ・ピザ・総菜類などの加熱加工品やスポーツ飲料など，製造段階で加熱工程のある食品・飲料からは，思い掛けない耐熱性菌の事故が多発しています．土壌・環境中のカビが食材に一次汚染し，加熱加工により胞子活性化のため発芽，菌糸が発育するのが原因です．耐熱性菌については，形態観察と同定，耐熱性データ情報を重点的に記述しました． 日本には伝統的な食文化があり，外国にない農水産物が作られています．調査対象も多く，多様なカビが見られます．蜂蜜のハチノスカビ，冷蔵生肉のエダケカビ，メロンを腐敗し食中毒の原因になったトマトばら色かび，ソースに発生する好酢菌などのほか，浴室・冷蔵庫・窓などの室内環境に多いカビ・アレルゲン・ヒトや家畜の病原になる黒色真菌などの記載もあります． 著者は1955-92年，国立衛生試験所に勤務，農学博士．

This book constitutes the refereed proceedings of the 21st Asian Symposium on Programming Languages and Systems, APLAS 2023, held in Taipei, Taiwan, during November 26–29, 2023.The 15 full papers included in this book are carefully reviewed and selected from 32 submissions. They were organized in topical sections as follows: semantics, logics, and foundational theory; design of languages, type systems, and foundational calculi; domain-specific languages; compilers, interpreters, and abstract machines; program derivation, synthesis, and transformation; program analysis, verification, and model-checking; logic, constraint, probabilistic, and quantum programming; software security; concurrency and parallelism; tools and environments for programming and implementation; and applications of SAT/SMT to programming and implementation.

Cancer Genes is a comprehensive list of the most critical genes known to contribute to cancer imitation and progression. The book delves into their location on each chromosome, providing valuable insights into the mechanisms of cancer gene dysregulation and genetic mutations which provide cancer cells with an advantage during each stage of tumorigenesis. The reference will familiarize readers with the location of cancer genes and equip them with the necessary information to identify relevant gene expression targets for research aimed at preventing the disease. The book is divided into two volumes focusing on cancer-causing genes found in chromosome pairs 1-12 (volume 1), and chromosomes 13-23 (volume 2). A key features of the book is a detailed reference list for advanced readers. The compilation is therefore a quick and handy reference on cancer causing genes for researchers, medical professionals, and anyone interested in understanding the genetic basis of cancer.

This book summarizes the state-of-the-art advances in the area of computational modelling of molecule-based magnets. Nowadays, various computational tools based on DFT, ab initio methods and other techniques are gaining attention in molecular nanomagnets and are successfully used to solve several outstanding problems in this area. This contributed volume discusses the theoretical foundation of the modelling of molecular magnets, starting from fitting the experimental magnetic data of very large molecules to the theory of pseudo-spin Hamiltonian approach and spin-phonon relaxations mechanisms, while it also presents examples of contemporary applications of both transition metal and lanthanide molecular magnets. In addition, the transport characteristics of molecules when placed at an interface and how these assemble on surfaces are also reviewed. This book is a great tool for researchers working in the fields of molecular magnetism and computational/theoretical chemistry and will also benefit graduate students specializing in physical-inorganic chemistry and molecular modelling.Chapter 6 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

This volume contains eight chapters that detail advances in health and disease. Chapter One presents state-of-the-art research of Ovalbumin bioactive peptides (OVA-BAPs). Chapter Two focuses on providing a comprehensive overview of OVA in human nutrition and the food industry. Chapter Three elaborates on an approach to identify critical factors affecting the pharmacokinetics in rats of several formulations of acyclovir. Chapter Four provides a comprehensive review of the literature on the pathophysiology and current therapies of CP-induced hemorrhagic cystitis. Chapter Five focuses on endocrine immune-related adverse events (irAEs), including their pathogenesis, risk factors, diagnostic processes, clinical characteristics, and management. Chapter Six discusses the benefits of beetroot juice in resistance training. Chapter Seven presents the challenges and opportunities in postgraduate medical education. Lastly, Chapter Eight discusses biologically encapsulated nanoparticles, which are used for improving drug interaction to control and cure disease.

Biosensing: Methods, Applications, and Technology'is a comprehensive guide to the rapidly expanding field of biosensors. The book delves into the various methods used in biosensing, including electrochemical, optical, and piezoelectric techniques, and explores the latest advancements in each area. It also examines a wide range of applications for biosensors, such as medical diagnostics, food safety, and environmental monitoring. With an emphasis on practical applications and cutting-edge technology, this book is essential reading for scientists, engineers, and researchers working in biosensing and related fields. Whether you're a student or an industry professional, this book will provide you with a thorough understanding of the latest developments in biosensing and equip you with the knowledge you need to stay ahead of the curve in this exciting field.

Insecticidal Proteins and RNAi in the Control of Insects, Volume 65 in the Advances in Insect Physiology series, highlights new advances in the field, with this new volume presenting interesting chapters on topics including Insecticidal RNAi delivered as biopesticide, Cry toxins, Vip3 insecticidal proteins: Structure and Mode of Action, New plant/other bacteria toxins, Engineered insecticidal proteins, Resistance to insecticidal proteins, and Photorhabdus toxins across Gram-negative bacteria. Each chapter is written by an international board of authors. - Provides the authority and expertise of leading contributors from an international board of authors - Presents the latest release in the Advances in Insect Physiology series - Updated release includes the latest information on the Insecticidal proteins and RNAi in the control of Insects

Advances in Immunology, Volume 159, the latest release in a long-established and highly respected publication, presents current developments and comprehensive reviews in immunology with chapters covering topics such as the cGAS-STING pathway. - Presents current developments and comprehensive reviews in immunology - Provides the latest in a longstanding and respected serial on the subject matter - Focuses on recent advances in immunology

The two-volume set LNCS 13451 and 13452 constitutes revised selected papers from the CICLing 2019 conference which took place in La Rochelle, France, April 2019.The total of 95 papers presented in the two volumes was carefully reviewed and selected from 335 submissions. The book also contains 3 invited papers. The papers are organized in the following topical sections: General, Information extraction, Information retrieval, Language modeling, Lexical resources, Machine translation, Morphology, sintax, parsing, Name entity recognition, Semantics and text similarity, Sentiment analysis, Speech processing, Text categorization, Text generation, and Text mining.

The essential reader on the philosophical foundations and implications of artificial intelligence, now comprehensively updated for the twenty-first century.In the quarter century since the publication of John Haugeland's Mind Design II, computer scientists have hit many of their objectives for successful artificial intelligence. Computers beat chess grandmasters, driverless cars navigate streets, autonomous robots vacuum our homes, and ChatGPT answers existential queries in iambic pentameter on command. Engineering has made incredible strides. But have we made progress in understanding and building minds? Comprehensively updated by Carl Craver and Colin Klein to reflect the astonishing ubiquity of machine learning in modern life, Mind Design III offers an essential collection of classic and contemporary essays on the philosophical foundations and implications of artificial intelligence. Contributions from a diverse range of philosophers and computer scientists address the nature of computation, the nature of thought, and the question of whether computers can be made to think. With extensive new material reflecting the explosive growth and diversification of AI approaches, this classic reader equips students to assess the possibility of, and progress toward, building minds out of computers.New edition highlights: New chapters on advances in deep neural networks, reinforcement learning, and causal learningNew material on the complementary intersection of neuroscience and AIOrganized thematically rather than chronologically Brand new introductions to each section that include suggestions for coursework and further reading

​This book presents drug repurposing strategies to combat infectious diseases and cancer. It discusses key experimental and in silico approaches for modern drug repositioning, including signature matching, molecular docking, genome-wide associated studies, and network-based approaches aided by artificial intelligence. Further, the book presents various computational and experimental strategies for better understanding disease mechanisms and identify repurposed drug candidates for personalized pharmacotherapy. It also explores the databases for drug repositioning, summarizes the approaches taken for drug repositioning, and highlights and compares their characteristics and challenges. Towards the end, the book discusses challenges and limitations encountered in computational drug repositioning.

'Nearly 100 expert authors who discuss the evidence-based gold standards for diagnostics and tests for optimal detection of multisystem disorders, patient management, and transitions of care. In these chapters, learners will gain greater understanding of the etiology and pathophysiology of acute and critical illnesses, and the latest in advanced pharmacologic and nonpharmacologic therapies… We congratulate the Editors and chapter authors for their efforts in developing a clearly outlined and accurate text for AGACNP use—truly the first of its kind.'—April N. Kapu, DNP, APRN, ACNP-BC, FAANP, FCCM, FAAN Associate Dean for Clinical and Community Partnerships Vanderbilt University School of Nursing Professor of Nursing, Vanderbilt University School of Nursing 2021-2023 President, American Association of Nurse Practitioners —Ruth Kleinpell, PhD, APRN, ACNP-BC, FAANP, FAAN, MCCM Associate Dean for Clinical Scholarship, Vanderbilt University School of Nursing Professor of Nursing, Vanderbilt University School of Nursing 2017 President, Society of Critical Care Medicine Encompassing all of the knowledge required to fulfill AACN and NONPF competencies and scope of practice, this comprehensive, evidence-based text is the first written specifically for Adult Gerontology Acute Care NP students and practitioners. With contributions from over 100 respected practitioners in the field, it encompasses the most current information on the evaluation, diagnosis, and management of common conditions, and integrates advanced nursing practice competencies including leadership skills, understanding of complex health care systems, and interprofessional team practice. The text is organized by body system for ease of reference. Each chapter includes a review of the current standard of care for a particular topic, including assessment, differential diagnostic modalities, interprofessional collaboration, evidence-based treatment, and goals for transitions of care. Also covered are specific challenges and professional considerations in acute care. Clinical pearls and key takeaway boxes are woven throughout to underscore essential information. Special topics on palliative care, pain, and pain management are also covered. Instructor resources include PowerPoints and a test bank. Key Features: A comprehensive acute care textbook written by NPs for NPs Organized by body system for ease of reference Integrates advanced nursing practice competencies Promotes leadership skills, helps students to understand complex health care systems, and embodies core principles of interprofessional team practice Includes clinical pearls, key takeaway boxes, evidence-based practice resources Delivers robust teaching/learning package

Design thinking is a ground-breaking problem solving process which combines logic, intuition, and systematic reasoning to develop long-term solutions to common engineering challenges and to inspire innovation. Serving as an introduction to the concept as well as a reference point, the book is essential reading for all engineers. Following a design thinking approach itself to structure its contents, this book is a key introduction to the process, providing case studies to demonstrate the multiple practical uses of the method. Relevant to sectors such as software development, Mobile App Development, sustainability and Artificial Intelligence, the book has a wide range of applications. The inclusion of a tools section to focus in on popular apps and software aids the reader in practically using the design thinking method. It ends by looking forward to the future prospects of design thinking, and the innovations which it can inspire. The book will be of interest to engineers of all professions, including design and management.

Seit 2022 begeistert ChatGPT Millionen von Menschen mit seinen erstaunlichen und skurrilen Fähigkeiten. Doch die künstliche Intelligenz entwickelt sich rasant weiter: GPT-4 und seine Rivalen sind bereit, die Medizin zu revolutionieren. Ob Sie im Gesundheitswesen arbeiten, seine Dienste in Anspruch nehmen oder einfach nur gesund bleiben wollen - Sie sollten diese Technologien kennen und nutzen! Was können sie bereits, wo liegen ihre Grenzen? Was dürfen sie auf keinen Fall? Informieren Sie sich aus erster Hand über die neuesten Fortschritte. Folgen Sie drei Expert•innen, die GPT-4 schon vor seiner Veröffentlichung ausgiebig getestet haben, und entdecken Sie das enorme Potenzial von GPT-4: bessere Diagnosen, effizientere Behandlungen, schnellere Forschung, aber auch die Gefahren. Sie lesen echte GPT-4-Gespräche - mal genial, mal peinlich, alle mit wertvollen Erklärungen, kritischen Anmerkungen, aktuellen Erkenntnissen und Einblicken in Chancen und Risiken. Lernen Sie außerdem, wie Sie GPT-4 gezielt Fragen stellen, um optimale Antworten auf Ihre Fragen zu erhalten. Das Buch richtet sich an alle, die sich für KI im Gesundheitswesen interessieren, egal ob als Arzt•in, Patient•in, Gesundheitsmanager•in, Politiker•in oder Investor•in. Das Buch zeigt, dass die KI-Revolution in der Medizin den Menschen nicht ersetzen, sondern unterstützen und stärken will, um eine effektivere und individuellere Versorgung zu ermöglichen. Das Buch ist ein Muss für alle, die an diesem wichtigen Zukunftsthema und darüber hinaus teilhaben wollen.

This book is a practical guide for applying neuromuscular principles to orthodontics. It is designed to meet the needs of dental students and practitioners. The book provides a solid foundation in neuromuscular dentistry, explaining the basic anatomy and ideal functioning of the mouth and jaw. It covers important techniques like mandibular tracking, TENS, and surface EMG, which are used for diagnosing, planning treatment, and monitoring progress. The last chapter features case studies with Kinesiography, showing the long-term outcomes after treatment. The information in the book is presented clearly and written in an easy-to-understand style.

With the global population estimated to reach 9 billion by 2050, agricultural production must align with this growth to alleviate any further burden on our current food systems. More sustainable and alternative modes of production are required to ensure that this overburden doesn't occur and that the food security of millions isn't compromised in the process. Advances in cultured meat technology reviews the growing interest and emergence in the field of cellular agriculture as one possible solution to achieving this. The book reviews the major technologies used in cultured meat product development, including cell line sourcing, cell growth media, bioreactors for cell multiplication and tissue engineering using scaffolds. The need to establish regulatory frameworks to permit the creation and trade of this new type of product is also highlighted, as is the key issue of consumer acceptance of this new technology. In its comprehensive exploration of the recent advances in cultured meat, the book showcases the potential of cultured meat production in alleviating the burden on our food systems, as well as some of the welfare and sustainability issues that arise during traditional livestock production.

If only it were possible to develop automated and trainable neural systems that could justify their behavior in a way that could be interpreted by humans like a symbolic system. The field of Neurosymbolic AI aims to combine two disparate approaches to AI; symbolic reasoning and neural or connectionist approaches such as Deep Learning. The quest to unite these two types of AI has led to the development of many innovative techniques which extend the boundaries of both disciplines. This book, Compendium of Neurosymbolic Artificial Intelligence, presents 30 invited papers which explore various approaches to defining and developing a successful system to combine these two methods. Each strategy has clear advantages and disadvantages, with the aim of most being to find some useful middle ground between the rigid transparency of symbolic systems and the more flexible yet highly opaque neural applications. The papers are organized by theme, with the first four being overviews or surveys of the field. These are followed by papers covering neurosymbolic reasoning; neurosymbolic architectures; various aspects of Deep Learning; and finally two chapters on natural language processing. All papers were reviewed internally before publication. The book is intended to follow and extend the work of the previous book, Neuro-symbolic artificial intelligence: The state of the art (IOS Press; 2021) which laid out the breadth of the field at that time. Neurosymbolic AI is a young field which is still being actively defined and explored, and this book will be of interest to those working in AI research and development.

This book offers a comprehensive review of the latest developments in medicinal mushroom biochemical engineering and biotechnology, and it also analyses the circular economy of mushroom bioproduction. Divided into 13 chapters, the book begins with a historical perspective of medicinal mushrooms, followed by authoritative chapters that explore the farming of medicinal mushrooms and bioeconomy, as well as the limitations of using medicinal mushrooms to produce metabolites. Subsequent chapters cover topics such as solid-state and submerged cultivation of medicinal mushroom mycelia in bioreactors, pilot and industrial bioreactor cultivation experiences, downstream processing of medicinal mushroom products, and biochemistry of medicinal mushroom bioactive compounds. Particular attention is given to the recent genetic engineering techniques applied in mushroom cultivation. The book closes with a chapter devoted to the health and clinical benefits of medicinal fungi, where readerswill find expert insights into the therapeutic implications of medicinal fungi. In this book, readers will find an authoritative perspective on the past, present and future of medicinal mushrooms, and will also learn about some recent clinical studies with isolates from these natural products. Given its breadth, this book will appeal to biotechnologists working in mushroom cultivation, as well as to professionals interested in traditional pharmacy and medicine.

Eggs are one of the most popular foods worldwide due to their great taste and versatility, economical value and high nutritional content. The egg plays an important role in the human diet, both for the nutritional value of its many components (e.g., proteins, vitamins, minerals, choline, specific long chain fatty acids) as well for its wide range of functional characteristics, including foaming, gelling and emulsifying properties. The egg sector is a vibrant field with many new developments in terms of production, processing and commercialization as well as research. Since the beginning of the 21st century, the global production of eggs has grown by 69.5%, farm production systems have evolved to improve the welfare of laying hens, many eggshell and egg products have been developed to address the changing demands of consumers and our knowledge of the composition of the egg has been boosted by the latest gene-based technologies. Information on the science and technology of egg and egg processing is essential to governments, academia and industry.The Handbook of Egg Science and Technology aims to be the first book providing a complete source of information about egg science and technology, covering topics such as world egg production, marketing of eggs, chemistry of egg components, functional properties of egg components, egg processing, egg product development, eggshell quality, grading, egg microbiology, egg pasteurization, egg nutrition and bioactive components, egg biotechnology and sustainability of egg production.Features Includes the most current and comprehensive scientific and technical information about egg science and technology Presents an ideal guide for professionals in related food industries, egg business consultants, regulatory agencies and research groups Answers the need for a comprehensive textbook for upper-level undergraduate and graduate courses in food science, animal science and poultry departments A global panel of experts in the field of egg science was gathered with the aim to provide the most updated information and development on many topics likely to interest readers ranging from academia and food science students to managers working in the food production and egg processing sectors. This handbook is an excellent resource for the food and poultry industry, R&D sectors, as well as experts in the field of food and nutrition.

Ensure optimal outcomes from each shoulder, elbow, and knee sports medicine surgery with the consistent, step-by-step approach offered in this comprehensive reference. Surgical Techniques of the Shoulder, Elbow, and Knee in Sports Medicine, 3rd Edition, covers both open and arthroscopic surgeries, providing the expert guidance you need on everything from patient positioning, anatomy, relevant biomechanics and the latest orthopaedic surgery techniques, through pearls and pitfalls and post-operative care. Contributing authors are renowned sports medicine surgeons who equip you with a global perspective on the most recent orthopaedic advances. - Covers the latest open and arthroscopic techniques for both common and not-so-common sports medicine pathologies. - Offers a comprehensive approach to each pathology including rehabilitation protocols and return-to-play criteria. - Contains more than 15 new chapters: First-time Shoulder Dislocation, Ulnar Collateral Ligament Reconstruction (various techniques), Managing Bone Loss on the Humeral Head, Cartilage Allografts for the Treatment of Cartilage Lesions of the Knee, and many more. - Provides up-to-date information on timely topics such as complex decision making for the patellofemoral joint, biologics and injection therapy for the management of osteoarthritis, and primary ACL repair techniques. - Highlights step-by-step text with numerous high-quality illustrations, surgical photographs, and MRIs and radiographs. - Includes access to an online surgical video collection covering Arthroscopic Rotator Cuff Repair: Double Row Techniques; Arthroscopic Repair of Multidirectional Instability of the Shoulder; Ulnar Collateral Ligament Repair and Reconstruction: DANE Technique; Double Bundle Anterior Cruciate Ligament Reconstruction; and Management of Proximal Tibiofibular Instability. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

Encyclopedia of Food Safety, Second Edition, Four Volume Set provides an authoritative one-stop reference work covering all aspects of the field. Specific focus lies in the book's coverage of key industry developments over the last ten years, including: (i) detailed understanding of infectious agents and toxins and their route into the food chain; (ii) sophisticated detection and identification methods; (iii) effective control mechanisms, like heat treatment, refrigeration and sanitizers; (iv) education of food processors, handlers and consumers about safe food handling practices; (v) sanctioned food production, processing, storage and transport control protocols, like HACCP; and (vi) a strong policy and regulatory environment. With approximately 270 outstandingly written chapters from the world's leading experts in food science, the book covers all aspects of food safety along the entire food chain and in one complete work, thus providing the ideal reference tool for professionals working across the multiple scientific disciplines and technologies that constitute modern food safety. - Provides an up-to-date,'one-stop'resource that will bridge the gap in current knowledge - Intuitively organized into 9 sections over 4 volumes – providing an excellent overview of the field - Contains approximately 270 chapters written by a global team of experts in food science and safety - Ensures relevance to scientists across a variety of fields, such as food science, agriculture, health and climate change

Overexpression of receptor tyrosine kinases (RTKs) has been implicated in cancer. Increasing evidence suggests that dysregulation of RTKs is reported in many neurodegenerative and psychiatric disorders. Receptor Tyrosine Kinases in Neurodegenerative and Psychiatric Disorders provides a fundamental, pragmatic map of RTKs structure, activation, functions, mechanism of action, gene regulation, and signaling pathways in developing central nervous system (CNS), adult normal CNS, neurodegenerative and psychiatric disorders. Additionally, the structure, function, activation, and therapeutic potential of many growth factors have been covered. Here, international experts in the field offer a comprehensive discussion of results of pre-clinical and clinical studies of repositioning of anti-cancer receptor tyrosine kinase inhibitors (RTKIs) and other promising protein kinase inhibitors in various neurodegenerative disorders including, Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, Huntington's disease, and multiple sclerosis, and psychiatric disorders including, anxiety, depression, alcohol use disorder, and schizophrenia. In addition, the book discusses the obstacles and opportunities for the potential repositioning of kinase inhibitors in neurodegenerative and psychiatric disorders. - Provides a thorough overview of RTKs biology and their role in health and disease progression and modulation - Highlights RTK families and the numerous receptors within each subfamily - Examines RTKIs and other protein kinase inhibitors in pre-clinical and clinical trials in both neurodegenerative and psychiatric disorders - Gives future directions of possible safe effective targeted RTKIs and other protein kinase inhibitors that may be repositioned in various neurodegenerative and psychiatric disorders - Includes chapter contributions from renowned experts in biology, pharmacology, neurology, psychiatry, and oncology

The Art of 2D Transesophageal Echocardiography provides in a practical and systematic way an overview of basic concepts and state of-the-art techniques in transesophageal echocardiography. It summarizes established application, provides hundreds of real-time videos of various cardiac diseases that expand the knowledge of every cardiologist, intensivist, and cardiovascular physicians in their daily practice of transesophageal echocardiography. - Illustrates the standard and the alternative 2D transesophageal echocardiography views used to perform an optimal and comprehensive echocardiographic examination - Illustrates echocardiographic evaluation of the native and prosthetic valves of the heart - Covers the left atrial appendages morphology, function, and detection of left atrial thrombi - Covers the diagnostic value of 2D transesophageal echocardiography of the aortic disease such as aortic atheroma, aneurysm, and aortic dissection - Covers echocardiographic examination of adult congenital heart diseases and cardiac masses - Covers the application of 2D transesophageal echocardiography during cardiac interventional procedures in structural heart diseases - Related real cases study are included and discussed following each chapter - The digital format contains hundreds of real-time videos and captures echo images as a guide for practicing clinicians

Powerful solar explosions, such as flares and coronal mass ejections, greatly disturb the electromagnetic environment around the Earth and the atmosphere. They may even impact various social systems—communications, positioning, electric power supply, aviation and activities in space. Such variations in the space environment, which can influence human activities, are called “space weather.” The space weather disaster caused by a solar explosion is a potential risk in modern society. To reduce and mitigate space weather impacts, it is essential to understand the structure and dynamics of the solar–terrestrial environment and to predict the variations. This book comprehensively describes space weather, from the basics of related sciences to the possible social impacts. It was compiled based on a national research project on solar–terrestrial environment prediction conducted in Japan recently. It consists of four parts: the linkage between space weather and society; the magnetosphere of the Earth and space weather prediction; solar storms and space weather prediction; and long-term prediction of solar cycle activity and climate impacts. Each chapter covers the basics and applications of each area, which helps readers gain a broad understanding of the subject matter throughout the book. In addition, readers are able to select and read the topics they are most interested in. It is especially valuable for undergraduate and graduate students and young researchers studying space weather and related topics, and is further helpful for experts in various industries related to space weather disasters. The translation was done with the help of artificial intelligence (machine translation by the service DeepL.com). The present version has been revised technically and linguistically by the authors in collaboration with a professional translator.

This atlas is written to provide readers with the clinical and pathological presentation of the broad spectrum of pigmentary skin disorders (PSD). This book is divided into six parts and covers diseases of hypopigmentation, disorders of hyperpigmentation, hyperpigmentation coexisting with hypopigmentation, pigmentary disorders of the hair, nails, and mucous membranes, and neoplasms with dyschromatosis encountered in clinical practice. Written by experts with rich experience in the field, it will be an invaluable reference not only for dermatologists, cosmetologists, and geneticists but also for anyone interested in the exciting area of PSDs.

Encyclopedia of Cell Biology, Second Edition, a Six Volume Set, has established itself as a fundamental reference work, providing broad coverage of the field in four main sections (Molecular, Organizational, Functional, Translational and Pathological Aspects of Cell Biology). This second edition revisits and expands each section, with entries on topics not covered in the first edition, including Crispr. The whole work is updated, providing greater coverage of specialized cell function and translational applications, and putting greater emphasis on these topics in graduate/medical teaching. New overview chapters and subsections provide a simplified cell biology text that can be used by instructors. The new version includes a standard template for each chapter, making the content easier to navigate, as well as inserts and graphics which provide summaries of key points in each chapter. - Provides the authority of a team of outstanding scientists in the field - Presents a comprehensive, up-to-date resource, covering both basic and translational aspects of cell biology - Offers high quality content at a competitive market price

Many books have been published about physician-assisted death. This book offers a comprehensive and in-depth examination of that subject, but it also extends the discussion to a broader range of end-of-life decisions including suicide, palliative care and sedation until death. In every jurisdiction that has laws permitting some kind of physician-assisted death, a central point of controversy is whether such assistance should only be available to dying patients, or to everyone who wants to end his life. The right to determine the manner and time of one's own death, however, does not necessarily mean that physicians should be permitted to cooperate in ensuring a quick and peaceful death. In this book, Govert den Hartogh considers the fundamental and practical matters – including concrete issues of legal regulation – related to end-of life decision making. He proposes a two-tiered system. Everyone should have access to humane means of ending his life, if his decision to end it is voluntary, well-considered and durable. But doctors should only participate in a joint action of ending the patient's life on his request if they also are convinced of acting in the patient's best interests, in particular by ending intolerable and unrelievable suffering. And perhaps there is reason to restrict that second service to dying patients. The whole argument, however, depends on the extent to which, in both tiers of the system, we can design legal safeguards that will enable us to trust judgments about the requesting person's request and about his suffering. The book considers much new evidence in regard to this issue.What Kind of Death will appeal to researchers and advanced students working in bioethics, applied ethics, philosophy of law and health law.

Resource Recovery in Industrial Waste Waters provides a holistic approach for discovering and harnessing valuable resources from industrial wastewaters, the cutting-edge technologies required, and a discussion on the new findings. In three volumes, the books stress the importance of contaminated waters'remediation, including surface waters, municipal or industrial wastewaters and treating these waters as a new source of nutrients, minerals and energy. It introduces polluted waters as new and sustainable sources, rather than seeing wastewaters as only a source of hazardous organic and inorganic matters. Sections discuss wastewater treatment and recovery and contribute to generate a sustainable approach of wastewater by providing the main advantages and disadvantages of both wastewater/polluted water treatment and recovery. - Reviews the current status of industrial wastewater treatment methods - Discusses the growing need of resource recovery from industrial wastewater, along with the challenges - Describes the importance of water reuse for combating water scarcity by describing current techniques and challenges - Evaluates the potential of the current market and status towards industrial wastewater resource recovery - Considers cutting-edge technologies for resource recovery - Contains comprehensive discussions on possibility of almost all recoverable resources from industrial wastewater

Multifunctional Phase Change Materials: Fundamentals, Properties and Applications updates on phase change materials (PCMs) used for the storage of thermal energy as sensible and latent heat. This class of materials is the subject of intensive research, both fundamental and applied, as they substantially contribute to the efficient use and conservation of waste heat and solar energy. Different groups of materials have been investigated as PCMs, including inorganic systems (salt and salt hydrates), organic, e.g., paraffins or fatty acids, polymers, and finally, hybrid materials. Recent developments are focused on multifunctional PCMs that provide functional features apart from energy storage, such as desired optical or antibacterial properties. This book presents various synthesis approaches for functionalized materials, as well as specific interactions and self-organization effects in polymer/functionalized (nano)particle systems. It reviews the current state-of-the-art in multifunctional phase change materials for thermal energy storage applications by describing the fundamentals of energy storage, the main classes of PCMs, functionalization protocols, encapsulation methods and shape stabilization procedures. - Covers the most important developments in PCMs that have expanded rapidly over the last few years, including thermochromic and thermoelectric PCMs, as well as fluorescence-functionalized phase change materials - Includes the newest solutions in PCMs related to functionalization and shape stabilization, e.g., nano-encapsulation and electrospun ultrafine phase change fibers - Provides a multidisciplinary, comprehensive work that will be of interest for a wide readership active in various disciplines, from materials science to environmental engineering

Oxides for Medical Applications reviews the most important advances of oxides with optical, magnetic and electronic properties for biomedical applications. Owing to their unusual properties, oxides are expected to play a significant role in the prevention or early treatment of diseases. In addition to catalytically active artificial enzymes based on oxide materials—the book provides comprehensive coverage of the most relevant categories of oxide materials and their properties and applications. Since magnetic oxides are used extensively for a wide range of medical applications, there are numerous chapters that address these materials, including LSMO nanoparticles, ferrites, nanocatalysts, and more. Finally, practical considerations for the translation of these materials from the lab to the clinic are reviewed, including biocompatibility and toxicity of oxide nanoparticles, making this a suitable resource for researchers and practitioners in materials science and engineering in academia and the clinic. - Reviews the unique properties and synthesis strategies of oxide materials for medical applications - Provides an overview of the most relevant medical applications of oxide materials such as their use in biosensing, drug delivery, tissue engineering, and more - Discusses practical considerations of the commercial translation of oxide materials, including their biocompatibility

Regulating virtually all biological processes, the genome's 2,654 newly discovered variants of mature microRNAs – short ribonucleic acid molecules found in eukaryotic cells – hold a key role in the body's toolkit of regenerative and reparative capacities. Identifying how to activate and deliver these specialist molecules may aid in the repair and regeneration of major tissue and organ damage in future therapies. In MicroRNA and Regenerative Medicine, Second Edition, over 50 leading experts address foundational and emerging topics in the field. Concisely summarizing and evaluating key findings from new research and their translational application, contributors examine current and future significance of clinical research in the miRNA area. Coverage encompasses all major aspects of fundamental stem cell and developmental biology, including the uses of miRNA in cell and tissue plasticity, developmental biology, tissue repair, and regeneration. In particular, contributors provide focused coverage of methodologies for regenerative intervention and tissue engineering. Topics new to this edition include proteomic changes during tissue repair and regeneration, horizontal transfer of miRNAs in tissue regeneration, tissue stemness, peripheral nerve regeneration, miRNA as biomarkers, microRNA in pregnancy and embryo development, exogenous and diet derived microRNA in tissue development, ocular microRNA, mitochondrial microRNA, sensory hair cell death and regeneration, and microRNA in senescence. - Features chapter contributions from international leaders in the field, covering the spectrum from bench to bedside - Includes short, applied chapters offering focused discussion and practical examples - Incorporates multi-color text layout with more than 150 color figures to illustrate important findings

Mastitis is one of the main health issues in dairy production. The losses are not only economic, but also issues such as animal health and welfare, milk quality, antibiotic usage and the image of the dairy sector are important reasons to focus on mastitis control. Accordingly, mastitis is a topic that is well-studied worldwide. Although the scope of the studies may vary from the smallest unit, the gene, to the largest unit, a whole country, the final goal is to control mastitis more effectively. Effective mastitis control is based on knowledge from a wide range of fields, like infectious pressure, milking procedures, resistance, detection, diagnosis and treatment. However, science alone is not enough. To ensure effective mastitis control, research needs to be inspired by, and implemented in, dairy farming practice. This demands cooperation and communication between scientists, veterinarians, extension specialists and dairy farmers worldwide. This book gives the state of the art of mastitis research internationally. The contributions reflect not only current knowledge of mastitis control, but also provide ideas for effective mastitis control in practice.

This book reviews state of the art of polymeric biomaterials for regenerative medicine and highlights advances in both fundamental science and clinical practice. It summarizes the latest techniques in polymeric scaffold fabrication, delivery carriers, physiochemical property modulation, as well as their influence on the adhesion and performance of biomolecules, cells, and tissues. It also describes methods for creating biofunctional surfaces/interfaces and subsequently modulating the host response to implantable materials. Lastly, it discusses the applications of biomaterials and constructs in soft-tissue regenerative medicine. It is a valuable resource for materials scientists and engineers wishing to identify research priorities to fulfill clinical needs and provides physicians with insights into emerging novel biomaterials. This integrated approach also offers engineering students a sense of the relevance of materials science in the development of novel therapeutic strategies. In the second edition, most of the chapters are updated according to the latest progress of this research field. A new chapter on nerve regeneration is also included.

Fatigue is a major element in time limited ageing analysis for long term operation of nuclear power plants (NPPs). It is important to understand how cracks occur and grow as a result of fatigue, and then assess fatigue failure. In the design and operating phase of NPPs, it is essential to consider the concurrent loadings associated with the design transients, thermal stratification, seismically induced stress cycles, and all relevant loads due to the various operational modes. After repeated cyclic loading, crack initiation can occur at the most highly affected locations if sufficient localized micro-structural damage has accumulated. This publication provides practical guidelines on how to identify and manage fatigue issues in NPPs. It explains the mechanism of fatigue, identifies which elements are the major contributors, and details how fatigue can be minimized in the design phase for new NPPs.

In our daily lives, communication is prevalent. We don't just communicate because we want to; we need to. Often, we use words to understand each other. However, there are times when we observe people and try to comprehend their intentions. We rely on'body language'. This reliance propagates the misleading idea that people communicate with their bodies just as they do with words. This is where misunderstandings frequently occur, sometimes even due to incorrect concepts propagated by so-called experts. The result is a loss of trust among readers or, worse, the disruption of interactions and relationships. Through a science-based approach, this work is primarily dedicated to all readers aged 18 and above who are passionate about communication and keen to understand others. Additionally, professionals from various sectors will find practical concepts and references for research, study, and daily work.

Design Thinking, a method widely used in design business and management, has changed the landscape of contemporary design. Whereas in the past non-designers were called upon to serve as external consultants ad-hoc, in an effort to promote creativity and innovation most design teams now consist of a mix of designers and other professionals. The impact of this development on the design landscape in recent years is so far without thorough investigation and analysis of its various influences. This book comprises an edited collection of selected papers from the 13th Design Thinking Research Symposium (DTRS13) which offers an exploration of Design Thinking from theoretical, practical, and pedagogical perspectives as well as critical analysis of the design process.The book is arranged in five parts as follows:Part 1: Thinking about designPart 2: Design thinking in the studioPart 3: Design thinking in practice and professional training Part 4: Design teams of diverse backgrounds, Interdisciplinary projects Part 5: Design and nature; visual representation Providing a comprehensive source for new perspectives on design and Design Thinking, Expanding the Frontiers of Design is ideal for designers and design academics of all disciplines wishing to strengthen and innovate their practice, as well as industry leaders who seek to consolidate their business strategies and evolve their work.

The book deals with dual role of reactive oxygen species (ROS) which is beneficial and harmful at below and above threshold limits, respectively. To date, the emphasis has been laid only on ROS aspects damaging/ disrupting cellular machinery and inflicting crop productivity loss. The ROS is believed to be a hallmark of both abiotic and biotic stress. However, the recent researches have unambiguously established that the ROS at below threshold confers protection against both abiotic and biotic stress, augmenting crop productivity. This emphasizes for a proper understanding of ROS based physio-molecular mechanisms and their upgradation in crops to adapt them to stress conditions. As a result, the cultivation area of various economically important crops and their productivity and quality can be enhanced, arresting degradation of sites, improving environment quality and mitigating ill impact of climate change. The book encompasses recent information on positive and negative impactof ROS on stress tolerance mechanisms and their management in augmenting crop performance. The information has been well illustrated and categorized in several chapters crafted lucidly, maintaining connectivity and synergy with each other. The book provides up-to-date comprehensive scientific information dual role of ROS, hitherto neglected, in crop abiotic and biotic stress management that would immensely benefit and educate graduate/ post graduate students, entrepreneurs, researchers, scientists and faculty members alike.

The dependency on animal biotechnology in livestock industries has been increased in the recent past. The livestock production research has witnessed remarkable developments on biotechnological methods to produce the elite animal breeds. The global animal food requirement has been steadily increasing, and animal production needs to be increased as per the global needs. This book covers various aspects of animal biotechnology such as, reproductive biotechnologies in sheep and goats, oogenesis and folliculogenesis and ovarian disorders. This book focusses the discussion on proteomics and metabolomics, and separate chapters were dedicated to discuss these topics. The proteomics studies of animal viruses were discussed in this book, and this would be helpful to understand animal viral pathogenesis. The applications of metabolomics in livestock were discussed with focus on data analysis, identification of unknown compounds. The purpose of this book is to provide the recent research trends, and convert all this information to usable guide to professionals, researchers and students who are working the research area of animal biotechnology.

Supporting Sucking Skills in Breastfeeding Infants, Fourth Edition is an essential resource for healthcare professionals working with new breastfeeding families and infants. Using a multidisciplinary approach, it incorporates the latest research on infant sucking and clinical strategies to assist infants with breastfeeding. With an emphasis on skills, it focuses on normal sucking function in addition to difficulties based in anatomical, cardiorespiratory, neurological, or prematurity issues. The Fourth Edition has been extensively updated with new photos throughout and additional information on breastfeeding modifications for infants with structural issues, including micrognathia, orofacial clefts, and torticollis. The contributing authors also reflect on the latest breastfeeding research, including the mechanics of sucking, the normal anatomy of the floor of the mouth, the role of tongue tie in feeding difficulty, as well as strategies to support infants with neurological conditions.

Exploring how clouds influence radiation, circulation, and precipitation Clouds are an influential and complex element of Earth's climate system. They evolve rapidly in time and exist over small spatial scales, but also affect global radiative balance and large-scale circulations. With more powerful models and extensive observations now at our disposal, the climate impact of clouds is receiving ever more research attention. Clouds and Their Climatic Impacts: Radiation, Circulation, and Precipitation presents an overview of our current understanding on various types of clouds and cloud systems and their multifaceted role in the radiative budget, circulation patterns, and rainfall. Volume highlights include: Interactions of aerosol with both liquid and ice clouds Surface and atmospheric cloud radiative feedbacks and effects Arctic, extratropical, and tropical clouds Cloud-circulation coupling at global, meso, and micro scales Precipitation efficiency, phase, and measurements The role of machine learning in understanding clouds and climate The American Geophysical Union promotes discovery in Earth and space science for the benefit of humanity. Its publications disseminate scientific knowledge and provide resources for researchers, students, and professionals.

This book constitutes the refereed proceedings of the 26th Brazilian Symposium on Formal Methods, SBMF 2023, held in Manaus, Brazil, during December 4-8, 2023.The 7 full papers and 2 short papers presented in this book were carefully reviewed and selected from 16 submissions.The papers are divided into the following topical sections: specification and modeling languages; testing; and verification and validation.

This book discusses the latest developments in Poly (ADP-ribose) polymerase (PARP) inhibitor drug development. It focuses on the translational and clinical development of the latest drugs, as well as the evidence for regulatory approval of PARP inhibitors in multiple different molecular subtypes and tumor indications. The most-up-to-date information on basic scientific research on DNA repair pathways and the DNA Damage Response (DDR) is also covered. Every chapter contains insight into the preclinical, translational along with clinical aspects of a specific DDR inhibitor with key and expert opinion points reinforcing the most important concepts detailed to enable the reader to develop a deep understanding of the topic.Targeting the DNA Damage Response for Cancer Therapy comprehensively reviews the application of PARP and other DDR inhibitors across oncology disciplines. Therefore, it is a valuable resource for all medical professionals and researchers who use or who are researching the use of these inhibitors on a day-to-day basis.

This book constitutes the refereed proceedings of the 19th International Conference on Advanced Data Mining and Applications, ADMA 2023, held in Shenyang, China, during August 21–23, 2023.The 216 full papers included in this book were carefully reviewed and selected from 503 submissions. They were organized in topical sections as follows: Data mining foundations, Grand challenges of data mining, Parallel and distributed data mining algorithms, Mining on data streams, Graph mining and Spatial data mining.

The three-volume set LNAI 14195, 14196, and 14197 constitutes the refereed proceedings of the 12th Brazilian Conference on Intelligent Systems, BRACIS 2023, which took place in Belo Horizonte, Brazil, in September 2023. The 90 full papers included in the proceedings were carefully reviewed and selected from 242 submissions. They have been organized in topical sections as follows:Part I: Best papers; resource allocation and planning; rules and feature extraction; AI and education; agent systems; explainability; AI models; Part II: Transformer applications; convolutional neural networks; deep learning applications; reinforcement learning and GAN; classification; machine learning analysis;Part III: Evolutionary algorithms; optimization strategies; computer vision; language and models; graph neural networks; pattern recognition; AI applications.