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This book presents an overview of the hydrometeorological and hydrological studies and assists in tackling challenges posed by climate and land use land cover changes. The Ganga River is one of the major living streams on the planet earth and very important river system in India. This holy river is a lifeline for approximately five hundred million people. In the last few decades, River Ganges has been subjected to tremendous pressures with respect to both water quantity and water quality. This situation, already one of the alarming magnitudes, has been further provoked by hydrometeorological changes resulting in droughts, floods and reduced groundwater levels and river flows in addition to the poor river health. Thus, it is imperative to assess the various complexities and possible solutions for better management of River Ganges. This book is a valuable addition to the literature and contributes to research on River Ganges which will help better planning and management of Ganga river basin. The hydrological and hydrometeorological aspects covered in this book help practitioners, researchers, policymakers and other stakeholders.

This volume presents selected papers presented during the 4th International Conference on Transportation Geotechnics (ICTG). The papers address the geotechnical challenges in design, construction, maintenance, monitoring, and upgrading of roads, railways, airfields, and harbor facilities and other ground transportation infrastructure with the goal of providing safe, economic, environmental, reliable and sustainable infrastructures. This volume will be of interest to postgraduate students, academics, researchers, and consultants working in the field of civil and transport infrastructure.

This book provides practical policy recommendations that are useful for developing Asia and for accelerating poverty reduction plans in the rest of the world. Poverty reduction in all its forms remains one of the greatest challenges facing humanity. In developing Asia, rapid growth in countries and sub-regions such as China, India, and Southeast Asia has lifted millions out of poverty, but progress has been uneven. On the other hand, the current coronavirus (COVID-19) pandemic and the global economic recession that it has caused are pushing millions of people back into poverty. Poverty reduction, inclusive growth, and sustainable development are inseparable, and poverty reduction is the premise for sustainable development. The Sustainable Development Goals (SDGs) are a bold commitment to finish what we started and end poverty in all forms and dimensions by 2030. However, because of the current global recession, the world is not on track to end poverty by 2030. Given the aforementioned situation, if we plan to achieve the no-poverty target in line with the SDGs, governments need to reconsider their policies and economies need to allocate their resources for this aim. Owing to the importance of the topic, this book provides several thematic and empirical studies on the roles of small and medium-sized enterprises, local businesses and trusts, international remittances and microfinance, energy security and energy efficiency in poverty reduction, and inclusive growth.

Ecological intensification involves using natural resources such as land, water, soil nutrients, and other biotic and abiotic variables in a sustainable way to achieve high performance and efficiency in agricultural yield with minimal damage to the agroecosystems. With increasing food demand there is high pressure on agricultural systems. The concept of ecological intensification presents the mechanisms of ensuring high agricultural productivity by restoration the soil health and landscape ecosystem services. The approach involves the replacement of anthropogenic inputs with eco-friendly and sustainable alternates. Effective ecological intensification requires an understanding of ecosystems services, ecosystem's components, and flow of resources in the agroecosystems. Also, awareness of land use patterns, socio-economic factors, and needs of the farmer community plays a crucial role. It is therefore essential to understand the interaction of ecosystem constituents within the extensive agricultural landscape. The editors critically examined the status of ecological stress in agroecosystems and address the issue of ecological intensification for natural resources management. Drawing upon research and examples from around the world, the book is offering an up-to-date account, and insight into the approaches that can be put in practice for poly-cropping systems and landscape-scale management to increase the stability of agricultural production systems to achieve ‘Ecological resilience'. It further discusses the role of farmer communities and the importance of their awareness about the issues. This book will be of interest to teachers, researchers, climate change scientists, capacity builders, and policymakers. Also, the book serves as additional reading material for undergraduate and graduate students of agriculture, forestry, ecology, agronomy, soil science, and environmental sciences. National and international agricultural scientists, policymakers will also find this to be a useful read for green future.

This book provides a unique account of cross-sectoral innovations through efficient partnerships based on the hands-on experience of internationally renowned contributors specialised in the field of Science of Delivery. The challenges and lessons learned from large development initiatives based in Asia, and from the work undertaken by international research institutions, such as the FAO, are brought together in this book to benefit development agencies, policy makers, corporates, post graduate students, farmers'organizations, and those involved in supplying agricultural inputs and/or buying agricultural produce, particularly in developing countries within Asia and Africa. Through a number of case studies the book describes how the consortium approach of capacity building for equitable and efficient benefits, collective action, and convergence, will benefit millions of small farm-holders in different regions of Asia

This book reviews the applications of polyphenols in cancer treatment. The initial chapter of the book classifies different polyphenols and discusses their biological and chemical properties. The subsequent chapters then explore the diverse role of polyphenols in modulating signal transduction pathways in cancer including, cellular proliferation, differentiation, apoptosis, inflammation, angiogenesis, and metastasis. This book highlights the usefulness of polyphenol enriched seafood in modulating the anti-tumor and anti-inflammatory cytokine IFN-γ. The book also presents nanoformulation of polyphenol as a promising strategy for their enhanced bioavailability and targeted delivery. Lastly, the book examines the toxicity and safety evaluations of polyphenols as anticancer agents.

This book summarizes the advanced computational methods for mapping high-density linkages and quantitative trait loci in the rice genome. It also discusses the tools for analyzing metabolomics, identifying complex polyploidy genomes, and decoding the extrachromosomal genome in rice.Further, the book highlights the application of CRISPR-Cas technology and methods for understanding the evolutionary development and the de novo evolution of genes in rice.Lastly, it discusses the role of artificial intelligence and machine learning in rice research and computational tools to analyze plant-pathogen co-evolution in rice crops.

Computational Chemistry serves as a complement to experimental chemistry where the tools are limited. Using computational programs to solve advanced problems is widely used in the design and analysis of for example new molecules, surfaces, drugs and materials. This book will present novel innovations in the field, with real-life examples of where computational technologies serves as an indispensible tool.

Forests cover thirty-one percent of the world's land surface, provide habitats for animals, livelihoods for humans, and generate household income in rural areas of developing countries. They also supply other essential amenities, for instance, they filter water, control water runoff, protect soil erosion, regulate climate, store nutrients, and facilitate countless non-timber forest products (NTFPs). The main NTFPs comprise herbs, grasses, climbers, shrubs, and trees used for food, fodder, fuel, beverages, medicine, animals, birds and fish for food, fur, and feathers, as well as their products, like honey, lac, silk, and paper. At present, these products play an important role in the daily life and well-being of millions of people worldwide. Hence the forest and its products are very valuable and often NTFPs are considered as the ‘potential pillars of sustainable forestry'. NTFPs items like food, herbal drugs, forage, fuel-wood, fountain, fibre, bamboo, rattans, leaves, barks, resins, and gums have been continuously used and exploited by humans. Wild edible foods are rich in terms of vitamins, protein, fat, sugars, and minerals. Additionally, some NTFPs are used as important raw materials for pharmaceutical industries. Numerous industry-based NTFPs are now being exported in considerable quantities by developing countries. Accordingly, this sector facilitates employment opportunities in remote rural areas. So, these developments also highlight the role of NTFPs in poverty alleviation in different regions of the world. This book provides a wide spectrum of information on NTFPs, including important references. We hope that the compendium of chapters in this book will be very useful as a reference book for graduate and postgraduate students and researchers in various disciplines of forestry, botany, medical botany, economic botany, ecology, agroforestry, and biology. Additionally, this book should be useful for scientists, experts, and consultants associated with the forestry sector.

In this book, several functional foods or food ingredients, their mechanism of immune enhancing properties and use in food products have been discussed through seventeen chapters written by eminent authors. There are several medicinal plants which have significant role for immunity boosting such as Ashwagandha, Tulsi, Shatavari, Giloy, Aloe vera, Amla, Neem, licorice, garlic, ginger, turmeric, rosemary, black cumin, cinnamon, sage, thyme,fenugreek, peppermint, black pepper, clove etc. These have been discussed in detail.Note: T&F does not sell or distribute the hardback in India, Pakistan, Nepal, Bhutan, Bangladesh and Sri Lanka.

This book comprises select peer-reviewed proceedings of the international conference on Research in Intelligent and Computing in Engineering (RICE 2020) held at Thu Dau Mot University, Vietnam. The volume primarily focuses on latest research and advances in various computing models such as centralized, distributed, cluster, grid, and cloud computing. Practical examples and real-life applications of wireless sensor networks, mobile ad hoc networks, and internet of things, data mining and machine learning are also covered in the book. The contents aim to enable researchers and professionals to tackle the rapidly growing needs of network applications and the various complexities associated with them.

This book presents state-of-the-art coverage of synthesis of advanced functional materials. Unconventional synthetic routes play an important role in the synthesis of advanced materials as many new materials are metastable and cannot be synthesized by conventional methods. This book presents various synthesis methods such as conventional solid-state method, combustion method, a range of soft chemical methods, template synthesis, molecular precursor method, microwave synthesis, sono-chemical method and high-pressure synthesis. It provides a comprehensive overview of synthesis methods and covers a variety of materials, including ceramics, films, glass, carbon-based, and metallic materials. Many techniques for processing and surface functionalization are also discussed. Several engineering aspects of materials synthesis are also included. The contents of this book are useful for researchers and professionals working in the areas of materials and chemistry.

This book covers selected high-quality research papers presented at the International Conference on Big Data, Machine Learning, and Applications (BigDML 2019). It focuses on both theory and applications in the broad areas of big data and machine learning. It brings together the academia, researchers, developers and practitioners from scientific organizations and industry to share and disseminate recent research findings.

Rapidly growing interest in the role of organic cation transporters (OCTs) and plasma membrane monoamine transporter (PMAT) in central monoamine homeostasis makes this book especially timely, given its thematic alignment with the role of OCTs and PMAT in CNS. This book discusses latest insights into the field laying an emphasis on health, disease and therapeutics. The chapter, “General Overview of Organic Cation Transporters in Brain”, of this book is available open access under a CC BY 4.0 license at link.springer.com

The Middle East is known as the cradle of civilization. It was the crossroads of ancient empires and the birthplace of major world religions. Today it is the center of many world issues due to its economic, religious and political importance. Although it has lagged behind many other regions of the world in medicinal research, this has increased dramatically in recent years with increasing numbers of relevant publications and the country of Iran has spearheaded this progress. Much of the research has focused on increasing our understanding of the aging process and attempting to identify biomarkers and natural products to improve the human healthspan. This book provides a comprehensive overview of the research conducted in the Middle East on the health benefits of curcumin, a phytochemical derived from the famous spice turmeric. Hundreds of studies have now been published describing the health benefits of this spice. The importance of this research is exemplified by poor data regarding health and longevity as only 0.08% of the population in Iran consists of individuals over 90 years of age. This is approximately 10 times lower than the percentage of this same age group in the United Kingdom and the United States of America and almost 20 times lower than that in Japan. This book presents a series of reviews and meta-studies describing research which has resulted in identification potential new biomarkers and drug targets for age-related disorders. All of the studies have focussed on the testing of curcumin and related products, which have already shown some promising leads in age-related conditions such as heart-disease, diabetes, cognitive impairment and cancer. The authors in this series come from different centers and cities of Iran, including Mashhad, Tehran, Isfahan, Ahvaz, Birjand, Quchan and Yazd, and many of the chapters feature collaborations with other countries of the Middle East and throughout the world, including Brazil, Italy, Mexico, Oman, Poland, Switzerland, the United Kingdom and the United States of America. This underscores the emergence of the Middle East into this arena of research. The book will be of high interest to scientific and clinical researchers in the subject of aging and age-related disease, and to physicians and pharmaceutical company scientists since it gives insights into the latest strategies, biomarkers and targets involved in the mechanism of action of curcumin to promote healthy aging. It will also provide important information on disease mechanisms related to age-related disorders, as each chapter will be presented in the context of specific chronic diseases.

The field of transplant medicine has evolved significantly since the first kidney transplant was performed in 1954. Innovations in transplant immunosuppression have lowered the risk of organ rejection so that infectious complications are now the leading cause of hospitalization and mortality after solid organ transplant. Infection is also cited as the leading cause of non-relapse mortality after stem cell transplantation. As transplant centers have recognized the importance of transplant specific expertise in patient outcomes, the field of transplant infectious diseases has expanded into a recognized and highly valued subspecialty. International growth in solid organ and stem cell transplantation has outpaced access to such expertise, with some centers employing microbiology laboratory directors and transplant nephrologists as their lead infectious diseases consultants. This has been a particular challenge as the use of novel immunosuppressive regimens in new geographic and immigrant populations have fueled the emergence of new infection syndromes, with the initial presentation sometimes occurring in this most vulnerable patient population. This digital-first book is designed to meet the needs of practitioners engaged in transplant infectious disease practice who need more depth than they are able to find in UpToDate. It provides an overview of emerging infectious disease challenges with clinically relevant information regarding the epidemiology, diagnosis, management, and prevention of infections in solid organ and stem cell transplant recipients. Each chapter focuses on a clinical syndrome or pathogen with new or emerging implications for transplant patients. Given the rapidly evolving nature of emerging infections and topics in transplant infections, no resource has been published on these increasingly notorious issues; this this text is written by top, global experts who regularly update the material to ensure that readers will always have access to the most cutting edge material available. The editorial team consists of three experienced leaders in the field, all of whom have a strong record of scholarship and publication, as well as an international reputation. All three have focused their academic careers on emerging infectious diseases in transplantation, including a current and a past president of various infectious diseases and transplantation societies. The editors are also experienced reviewers and authors who have collaborated on multiple previous projects. All are committed to this project as a unique opportunity to make an important contribution to their field.

This book aims to provide a collection of early ideas regarding the results of applying risk and resilience tools and strategies to COVID-19. Each chapter provides a distinct contribution to the new and rapidly growing literature on the developing COVID-19 pandemic from the vantage points of fields ranging from civil and environmental engineering to public policy, from urban planning to economics, and from public health to systems theory. Contributing chapters to the book are both scholars and active practitioners, who are bridging their applied work with critical scholarly interpretation and reflection. The book's primary purpose is to empower stakeholders and decision-makers with the most recent research in order that they can better understand the systemic and sweeping nature of the COVID-19 pandemic, as well as which strategies could be implemented to maximize socioeconomic and public health recovery and adaptation over the long-term.

This book includes high-quality papers presented at the International Conference on Communication, Computing and Electronics Systems 2020, held at the PPG Institute of Technology, Coimbatore, India, on 21–22 October 2020. The book covers topics such as automation, VLSI, embedded systems, integrated device technology, satellite communication, optical communication, RF communication, microwave engineering, artificial intelligence, deep learning, pattern recognition, Internet of Things, precision models, bioinformatics, and healthcare informatics.

••Selected for Doody's Core Titles® 2024 with'Essential Purchase'designation in Complementary & Integrative Health••

Business management, project management and portfolio management can prove challenging in any context, whether individually or collectively. The first textbook to integrate general management and project portfolio management, Business Management by Portfolio explains the science behind these concepts. It also explains how this approach results in a people-oriented philosophy which attracts (and maintains) talented, creative, and goal-oriented individuals in a dynamic environment because it offers ample opportunities for growth and self-actualisation. Though many theories claim to incorporate efficiency alongside value-based leadership, current management theory and practice demand more.

This book presents select proceedings of the International Conference on Advances in Civil Engineering (ACE 2020). The book examines the recent advancements in construction management, construction materials, environmental engineering, geotechnical engineering, transportation engineering, water resource engineering, and structural engineering. The topics covered include sustainable construction process and materials, smart infrastructures, green building technology, global environmental change and ecosystem management, theoretical and analytical solutions for foundation engineering, smart transportation systems and policy, GIS applications in water resource management, structural analysis for blast and impact resistance, and soft computing techniques in civil engineering. The book will be useful for researchers and professionals in the field of civil engineering.

Climate change is one of the major challenges of modern times. Its impacts are manifold and vary from sea level rise (especially relevant to those living in coastal areas), to the increased frequency of extreme events such as cyclones and storm surges, which not only poses problems to property and infrastructure, but also to human health. Climate change is also associated with damages to the physical and natural environment, as well as to biodiversity. According to the 5th Assessment Report produced by the Inter-Governmental Panel on Climate Change (IPCC), many geographical regions across the world are moderately or highly vulnerable to climate change, whose impacts may be further exacerbated by other human-induced pressures. The above state of affairs illustrates the need for a better and more holistic understanding of how climate change affects countries and regions on the one hand, but also on how the many problems itcauses may be managed on the other, vis-a-vis a better ability to adapt. There is also a perceived need to showcase successful examples of how to duly address and manage the many social, economic and political problems posed by climate change around the world, in order to replicate and even upscale the successful ones. It is against this background that the Handbook of Climate Change Management has been produced. It contains papers prepared by scholars, social movements, practitioners and members of governmental agencies, undertaking research and/or executing climate change projects, and working with communities across all geographical regions. The Handbook focuses on'Research, Leadership, Transformation', meaning that it serves the purpose of showcasing the role these key areas play in respect of applied research, field projects and best practices to foster climate change adaptation worldwide.

This book covers the contemporary environmental issues faced by life on the planet and the role planetary microbiomes play in such issues. Providing insights on the net favorable and adverse effect of microbial processes, this volume covers both the spontaneous and anthropocentric events that impact climate change and life on the planet. The book describes the ecological significance of microbiomes associated with the kingdoms Plantae and Animalia with respect to climate change, natural and anthropogenic causes of climate change, microbial interactions in nature, planetary microbiomes and food security, climate change in relation to disease epidemiology and human health and engineering microorganisms to mitigate the consequences of climate change. The individual chapters in the intended book provide both theoretical and practical exposure to the current issues and future challenges of climate change in relation to the microbiomes. This collection should serve as ready reference to the researchers working in the area to reshape their future research in addressing the challenges of global climate change.

This book presents the proceedings of SympoSIMM 2020, the 3rd edition of the Symposium on Intelligent Manufacturing and Mechatronics. Focusing on “Strengthening Innovations Towards Industry 4.0”, the book presents studies on the details of Industry 4.0's current trends. Divided into five parts covering various areas of manufacturing engineering and mechatronics stream, namely, artificial intelligence, instrumentation and controls, intelligent manufacturing, modelling and simulation, and robotics, the book will be a valuable resource for readers wishing to embrace the new era of Industry 4.0.

Tackling the realities of the antimicrobial resistance (AMR) situation today is no longer uncommon. Many battles have been fought in the past since the discovery of antibiotics between man and microbes. In the tussle of new antibiotic modifications, the transmission of resistant genes, both vertically and horizontally unveils yet another resistant attribute for the microbe, for it only to be faced with a more powerful, wide spectrum antibiotic; the cycle continues-and the winner is yet to be known. This book aims to provide some insight into various molecular mechanisms, agricultural mitigation methods, and the One Health applications to maybe, just maybe, tip the scales towards us.

Despite significant progress in increasing agricultural production, meeting the changing dietary preferences and increasing food demands of future populations remains a significant challenge. Salinity, drought, water logging, high temperature and toxicity are abiotic stresses that affect the crop yield and production. Tolerance for stress is a important characteristic that plants need to have in order to survive. Identification of proper techniques at a proper time can make it easy for scientists to increase crop productivity and yield. In Engineering Tolerance in Crop Plants against Abiotic Stress we have discussed the possible stresses and their impact on crops and portrayed distinctive abiotic stress tolerance in response to different techniques that can improve the performance of crops.Features of the Book: Provide a state-of-the-art description of the physiological, biochemical, and molecular status of the understanding of abiotic stress in plants. Address factors that threaten future food production and provide potential solution to these factors. Designed to cater to the needs of the students engaged in the field of environmental sciences, soil sciences, agricultural microbiology, plant pathology, and agronomy. New strategies for better crop productivity and yield. Understanding new techniques pointed out in this book will open the possibility of genetic engineering in crop plants with the concomitant improved stress tolerance.

••Selected for Doody's Core Titles® 2024 in Clinical Genetics•• Medical Epigenetics, Second Edition provides a comprehensive analysis of epigenetics in health management, across a broad spectrum of disease categories and specialties, and with a focus on human systems, epigenetic diseases that affect these systems, and evolving modes of epigenetic-based treatment. Here, more than 40 leading researchers examine how each human system is affected by epigenetic maladies, offering an all-in-one resource on medical epigenetics not only for those directly involved with health care, but investigators in life sciences, biotech companies, graduate students, and others who are interested in applied aspects of epigenetics. Incorporating both diagnostic and prognostic epigenetic approaches, this volume also fully supports the application of epigenetics in precision medicine. This second edition of Medical Epigenetics, a volume in the Translational Epigenetics series, has been fully revised to address recent advances in disease epigenetics and role of epigenetics in precision medicine, with all-new chapters on skin cancer epigenetics, network analysis in medical epigenetics, machine learning in epigenetic diseases, and clinical trials of epigenetics drugs. - Features chapters from leading researchers and clinicians dedicated to the burgeoning role of epigenetics in medical practice - Covers emerging topics, including twin epigenetics, as well as epigenetics of gastrointestinal disease, muscle disorders, endocrine disorders, ocular medicine, pediatric diseases, sports medicine, noncoding RNA therapeutics, pain management and regenerative medicine - Organized from system disorders to multi-system disorders that involve epigenetic aberrations - Examines the role of epigenetics in precision medicine

This volume is a compendium of selected plant species of ethnobotanical value to the highland communities of popular Southeast Asia. “Traditional” knowledge held by local communities on their resources is always in flux and adapting to a quickly changing environment. New plants find their entry into the local pharmacopoeias, while existing ones maybe removed. Likewise, various local communities might find the same plant useful for completely different purposes. While compiling information on the species, authors have taken great care to ensure that the dynamic nature of ethnobotanical knowledge is represented adequately. Special emphasis has also been given to cultural value of species to the local communities in the region. The field (and thus the market) of ethnobotany and ethnopharmacology has grown considerably in recent years. Student interest is on the rise, attendance at professional conferences has grown steadily, and the number of professionals calling themselves ethnobotanists has increased significantly (the various societies (Society for Economic Botany, International Society of Ethnopharmacology, Society of Ethnobiology, International Society for Ethnobiology, and many regional and national societies in the field currently have thousands of members). The objective of this new Major Reference Work on Ethnobotany of Mountain Regions of Southeast Asia is to take advantage of the increasing international interest and scholarship on highland landscapes and communities. While ethnobotanical studies are now available from many regions of the world, no comprehensive encyclopedic volume on the highlands of popular SE Asia is available in the market. We include the best and latest research on a full range of descriptive, methodological, theoretical, and applied research on the most important plants for the region. Scholars in plant sciences worldwide will also be interested in the dedicated website for this volume and its dynamic content.

This book provides all aspects of the physiology, stress responses and tolerance to abiotic stresses of the Brassicaceae plants. Different plant families have been providing food, fodder, fuel, medicine and other basic needs for the human and animal since the ancient time. Among the plant families, Brassicaceae has special importance for their agri-horticultural importance and multifarious uses apart from the basic needs. Interest understanding the response of Brassicaceae plants toward abiotic stresses is growing considering the economic importance and the special adaptive mechanisms. The knowledge needs to be translated into improved elite lines that can contribute to achieve food security. The physiological and molecular mechanisms acting on Brassicaceae introduced in this book are useful to students and researchers working on biology, physiology, environmental interactions and biotechnology of Brassicaceae plants.

This volume comprises select papers presented during the Indian Geotechnical Conference 2018. This volume discusses concepts of soil dynamics and studies related to earthquake geotechnical engineering, slope stability, and landslides. The papers presented in this volume analyze failures connected to geotechnical and geological origins to improve professional practice, codes of analysis and design. This volume will prove useful to researchers and practitioners alike.

The problems related to the process of industrialisation such as biodiversity depletion, climate change and a worsening of health and living conditions, especially but not only in developing countries, intensify. Therefore, there is an increasing need to search for integrated solutions to make development more sustainable. The United Nations has acknowledged the problem and approved the “2030 Agenda for Sustainable Development”. On 1st January 2016, the 17 Sustainable Development Goals (SDGs) of the Agenda officially came into force. These goals cover the three dimensions of sustainable development: economic growth, social inclusion and environmental protection. The Encyclopedia of the UN Sustainable Development Goals comprehensively addresses the SDGs in an integrated way. It encompasses 17 volumes, each devoted to one of the 17 SDGs. This volume addresses SDG 2, namely'End hunger, achieve food security and improved nutrition and promote sustainable agriculture'and contains the description of a range of related terms, to allow for a better understanding and foster knowledge. Our planet produces enough food to feed everyone. Malnutrition and hunger are the result of inappropriate food production processes, bad governance and injustice. SDG 2 seeks to guarantee quality and nutritious food to ensure healthy life by adopting a holistic approach that involves various actions targeting different actors, technologies, policies and programs. These initiatives have to face challenges coming from extensive environmental degradation, loss of biodiversity and the interrelated effects of climate change.Concretely, the defined targets are:End hunger and ensure access by all people, in particular the poor and people in vulnerable situations, including infants, to safe, nutritious and sufficient food all year roundEnd all forms of malnutrition, including achieving the internationally agreed targets on stunting and wasting in children under 5 years of age, and address the nutritional needs of adolescent girls, pregnant and lactating women and older personsDouble the agricultural productivity and incomes of small-scale food producers, in particular women, indigenous peoples, family farmers, pastoralists and fishers, including through secure and equal access to land, other productive resources and inputs, knowledge, financial services, markets and opportunities for value addition and non-farm employmentEnsure sustainable food production systems and implement resilient agricultural practices that increase productivity and production, that help maintain ecosystems, that strengthen capacity for adaptation to climate change, extreme weather, drought, flooding and other disasters and that progressively improve land and soil qualityMaintain the genetic diversity of seeds, cultivated plants and farmedand domesticated animals and their related wild species, including through soundly managed and diversified seed and plant banks at the national, regional and international levels, and promote access to and fair and equitable sharing of benefits arising from the utilization of genetic resources and associated traditional knowledge, as internationally agreedIncrease investment, including through enhanced international cooperation, in rural infrastructure, agricultural research and extension services, technology development and plant and livestock gene banks in order to enhance agricultural productive capacity in developing countries, in particular least developed countriesCorrect and prevent trade restrictions and distortions in world agricultural markets, including through the parallel elimination of all forms of agricultural export subsidies and all export measures with equivalent effect, in accordance with the mandate of the Doha Development RoundAdopt measu

This first volume in a two-volume work enhances readers'understanding of antimicrobial resistance mechanisms in selected bacterial species that cause diseases in major food producing animals. It provides an overview of the current legislation and policies seeking to regulate the authorisation, manufacturing, distribution and use of veterinary antimicrobials in practice in a way that helps to contain the spread of antimicrobial resistance. The focus is put on Europe, without neglecting the global context. Moreover, attention is paid to various uses of antimicrobials in livestock, considering both their risks and benefits, from the distant past to the present. Growth promotion, prophylaxis, metaphylaxis, diagnostics and treatment are discussed not only with regard to food production and animal health, but also considering the One Health concept, which combines public and animal health with environmental aspects. A summary of various systems for monitoring the use of antimicrobials is provided, as well as an overview of the diseases that European veterinarians most often treat with antimicrobials. In closing, the book addresses the complexity of recent measures that are of key importance for antimicrobial stewardship, e.g. biosecurity, vaccination and other preventive tools including the newest technologies like smart farming. The complete two-volume work provides an extensive review of various aspects related to the use of antimicrobials in veterinary medicine, especially considering major food producing species, their most common infectious diseases and causative pathogens, and mainly focusing on the situation in Europe, without ignoring the global context. While Volume I discusses more general aspects of antibiotic use such as regulatory, laboratory and practical issues from different perspectives, Volume II more specifically discusses medical aspects and the use of antimicrobials in cattle, pigs, poultry and horses, as well as pharmacokinetics and pharmacodynamics, two of the most important factors determining the success of treatment. In both volumes, each chapter confronts the reader with open questions to stimulate further discussions and future research on the topics covered.

This book focuses on understanding urban vulnerability and risk mitigation, advancing good health and wellbeing, and analysing resilience measures for various Asian cities. Today, cities are the dominant human habitat, where a large number of environmental, social, cultural and economic factors have impacts on human health and wellbeing. Cities consist of complex, dynamic, socio-ecological, and technological systems that serve multiple functions in human health and wellbeing. Currently half of Asia's population is urban, and that figure is expected to rise to 66 percent by 2050. Since urban areas are often most vulnerable to hazards, the people living in them need good health infrastructure facilities and technological support at various scales. As such, the need of the hour is to enhance the adaptive capacity, strengthen resilience, reduce vulnerability, and take risk mitigation measures in urban areas, which requires a systematic approach based on science–policy interface that istransformative, trans-disciplinary and integrative for a sustainable urban future. Global sustainable development goals are closely tied to urban human health and wellbeing: (1) the third of the United Nations'Sustainable Development Goals is to “Ensure healthy lives and promote wellbeing for all at all ages” and (2) the eleventh is to “Make cities inclusive, safe, resilient and sustainable”. By addressing these goals, this book offers a highly useful resource for anyone concerned with healthy and resilient cities in Asia, today and tomorrow.

Publisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product. 25+ additional chapters available online! The classic guide to driving optimal patient outcomes using evidence-based medication therapies—updated with the latest advances and guidelines Presented in full color, Pharmacotherapy: A Pathophysiologic Approach, 11th Edition helps you deliver the highest-quality patient care through evidence-based medication therapy derived from sound pharmacotherapeutic principles. It takes you beyond drug indications and dosages, showing how to properly select, administer, and monitor drugs—everything you need to provide safe, effective drug therapy across all therapeutic categories. With all-new monitoring tables and authoritative content from 300 expert contributors, this new edition has been fully updated to reflect the latest evidence-based information and recommendations. You'll find Key Concepts at the beginning of each chapter, Clinical Presentation tables that summarize disease signs and symptoms, and Clinical Controversies boxes that examine the complicated issues faced by students and clinicians in providing drug therapy. Why Pharmacotherapy: A Pathophysiologic Approach is perfect for students, pharmacists, and other healthcare providers: • All chapters provide the most current, reliable, and relevant information available. • Key concepts kick off every chapter. • Clinical Presentation Tables summarize disease signs and symptoms. • The majority of sections include personalized pharmacotherapy content. • Clinical Controversies Boxes clarify the most complex drug therapy issues you'll face. • Diagnostic flow diagrams, treatment algorithms, dosing recommendations, and monitoring approaches have been updated in full color to distinguish treatment pathways. • Most disease-oriented chapters are enhanced by updated evidence-based treatment guidelines, which often include ratings of the level of evidence to support key therapeutic approaches. • Instructors who adopt this text are eligible for a PowerPoint presentation of all images and answers to Self-Assessment Questions! The most trusted guide of its kind for decades, Pharmacotherapy: A Pathophysiologic Approach is the go-to text for students and practitioners seeking clear, objective coverage of core pathophysiologic and therapeutic elements.

The Developing Microbiome: Lessons from Early Life focuses on the establishment of the microbiome in early life, exposing it as a key mediator of diseases and health throughout the lifecycle. The content presents a comprehensive view of the status of the field and draws real-world correlations to health and disease states. It collates the significant research being done in the pediatric microbiome research space and bridges the knowledge gap showing the factors that impact health and disease states throughout the lifecycle. Finally, it offers knowledge on how the microbiome is and can be manipulated to promote change. This is a perfect reference for both researchers and clinical scientists who are interested in the role of the infant microbiome in health and disease, as well as gastroenterologists and pediatricians looking to affect change in their patients. - Provides comprehensive coverage of the factors that influence microbiome development - Links research in pediatric patients to later life stages - Examines increasing evidence on the impact of the microbiome beyond the gut

For nearly 50 years, Sleisenger & Fordtran's Gastrointestinal and Liver Disease has been the go-to reference for gastroenterology and hepatology residents, fellows, physicians, and the entire GI caregiving team. Now in a fully revised 11th Edition, this two-volume masterwork brings together the knowledge and expertise of hundreds of global experts who keep you up to date with the newest techniques, technologies, and treatments for every clinical challenge you face in gastroenterology and hepatology. A logical organization, more than 1,100 full-color illustrations, and easy-to-use algorithms ensure that you'll quickly and easily find the information you need.Features new and expanded discussions of chronic hepatitis B and C, Helicobacter pylori infection, colorectal cancer prevention through screening and surveillance, biologic agents and novel small molecules to treat and prevent recurrences of inflammatory bowel disease (IBD), gastrointestinal immune and autoimmune diseases, and more.Offers reliable coverage of key topics such as Barrett's esophagus, gut microbiome, enteric microbiota and probiotics, fecal microbiota transplantation, and hepatic, pancreatic, and small bowel transplantation.Provides more quick-reference algorithms that summarize clinical decision making and practical approaches to patient management.Employs a consistent, templated, format throughout for quick retrieval of information.Includes monthly updates online, as well as more than 20 procedural videos.Expert Consult™ eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.

Under ongoing climate changes, natural and cultivated habitats of major crops are being continuously disturbed. Such conditions impose and exacerbate abiotic and biotic stressors. Drought, salinity, flood, cold, heat, heavy metals, metalloids, oxidants, irradiation, etc. are important abiotic stressors, while diseases and infections caused by plant pathogens, such as fungal agents, bacteria and viruses, are major biotic stresses. In many instances, stresses have become the major limiting factor for agricultural productivity and exert detrimental role on growth and yield of the crops. To help feed an ever increasing world population and to ensure global food security, concerted efforts from scientists and researchers have identified strategies to manage and mitigate the impacts of climate-induced stresses. This book, summarizing their findings, is aimed at crop improvement beyond such kind of barriers, by agronomic practices (genetics, breeding, phenotyping, etc.) and biotechnological applications, including molecular markers, QTL mapping, genetic engineering, transgenesis, tissue culture, various'omics'technologies and gene editing. It will cover a wide range of topics under environmental challenges, agronomy and agriculture processes, and biotechnological approaches. Additionally, fundamental mechanisms and applied information on stress responses and tolerance will be discussed. This book highlights problems and offers proper solutions for crop stress management with recent information and up-to-date citations. We believe this book is suitable for scientists, researchers and students working in the fields of agriculture, plant science, environmental biology and biotechnology.

A follow-up to Emerging Issues and Controversies in Infectious Diseases, this volume provides a comprehensive review of topical issues in infectious diseases, highlighting the controversies related to the newest findings and recommendations. Coverage includes trends and debates in HIV research, community-acquired pneumonia, H. pylori, progress in Hepatitis C treatment paired with the lack of progress on Hepatitis B, and the effects of climate change on infectious disease epidemiology, among others. This is an essential resource for practicing and academic physicians, investigators, residents, and fellows focused on infectious diseases, infection control, public health, and global health.

This book offers a collection of high-quality peer-reviewed research papers presented at the Second International Conference on Communication and Computational Technologies (ICCCT 2019), held at Rajasthan Institute of Engineering and Technology, Jaipur, Rajasthan, India, on 30–31 August 2019. In contributions prepared by researchers from academia and industry alike, the book discusses a wide variety of industrial, engineering and scientific applications of emerging techniques.

This book has comprehensively reviewed the latest information on pyrazoles, their preparations and uses. It provides extended ideas on pyrazole and its derivatives including their synthesis, chemistry, structure activity relationship (SAR) and therapeutic applications. The health promoting properties of these pyrazoles are discussed in this book with different therapeutic applications of pyrazole scaffold. Topics related to pyrazole and its analogues as potential anticancer, anti-angiogenesis, antiviral, antioxidative, anti-convulsive, anthelmintic, anti-inflammatory, antidiabetic agents are described in this book in detail. Furthermore, current status and future prospects of pyrazole moiety in drug discovery, importance of it in plant systems, its relevance in neurological drug discovery, its potency as herbicidal and antimicrobial agents have been enumerated through different chapters. In a summary, this book is a valuable resource for research scholars, academics, students, industrialists and subject experts working in the multidisciplinary fields like medicinal chemistry, synthetic chemistry, biochemistry, pharmacology, natural product chemistry and other related areas in the field of pyrazole derivatives drug discovery and research.

This book comprises select peer-reviewed proceedings of the International Conference on Recent Developments in Sustainable Infrastructure (ICRDSI) 2019. The topics span over all major disciplines of civil engineering with regard to sustainable development of infrastructure and innovation in construction materials, especially concrete. The book covers numerical and analytical studies on various topics such as composite and sandwiched structures, green building, groundwater modeling, rainwater harvesting, soil dynamics, seismic resistance and control of structures, waste management, structural health monitoring, and geo-environmental engineering. This book will be useful for students, researchers and professionals working in sustainable technologies in civil engineering.

Clinical Microbiology E-Book

Plant improvement has shifted its focus from yield, quality and disease resistance to factors that will enhance commercial export, such as early maturity, shelf life and better processing quality. Conventional plant breeding methods aiming at the improvement of a self-pollinating crop, such as wheat, usually take 10-12 years to develop and release of the new variety. During the past 10 years, significant advances have been made and accelerated methods have been developed for precision breeding and early release of crop varieties. This edited volume summarizes concepts dealing with germplasm enhancement and development of improved varieties based on innovative methodologies that include doubled haploidy, marker assisted selection, marker assisted background selection, genetic mapping, genomic selection, high-throughput genotyping, high-throughput phenotyping, mutation breeding, reverse breeding, transgenic breeding, shuttle breeding, speed breeding, low cost high-throughput field phenotyping, etc. It is an important reference with special focus on accelerated development of improved crop varieties.

The Gram-positive and spore-forming Bacilli are the most dominant group of bacteria that exist in various ecological niches on the earth. They represent one of the most important unmapped pools of biodiversity with immense potential of applications in agriculture, environment, and industry. As these bacteria are highly tolerant to stressful environment and enhance plant tolerance to harsh environment such as salinity, drought, and heavy metal toxicity, plant-associated Bacilli have high potential for promoting sustainable crop production. Many species of Bacilli are being commercially used as phytostimulator and biofertilizer. Some of them are applied as biopesticide for protecting crop plants from phytopathogens and insect pests. The Bacillus-based products are becoming popular in ecologically sound and climate resilient agricultural production system. In fact, Bacillus and allied species based formulations are already dominating the biopesticides market, although, to compete with other formulations and chemical alternatives, the biology of Bacillus had to be understood from perspective of such applications. Our understanding of the biology and molecular-basis of the beneficial effects of plant-associated Bacilli has greatly been progressed in recent years through genomics, metagenomics, post-genomics and metabolomics studies. The volume two of the series Bacilli and Agrobiotechnology comprehensively reviews and updates current knowledge of Bacilli as phytostimulant and biological control of plant pests. Better understanding the biology, ecology and mechanism of action of the beneficial strains of Bacilli will play a role in the development of products to support green biotechnology in agriculture and industries.

This book provides a comprehensive overview of the different water-associated infectious diseases and their linked pathogens with plausible strategies for their mitigation. Although, we are in the era of 21st century having most of the advanced technologies at hand, yet water-associated infectious diseases are the major contributors towards the worldwide morbidity and mortality. The book also focuses on the various implementation strategies of sustainable hygienic conditions, discusses the robust, and reliable policies and strategies on a global aspect to provide unprivileged people access to the basic sanitation, hygiene and water. In addition, the book discusses the possible indirect effect of global warming on the spread of infectious diseases through the distribution of associated vectors.

This book highlights the medical importance of and increasing global interest in herbal medicines, herbal health products, herbal pharmaceuticals, nutraceuticals, food supplements, herbal cosmetics, etc. It also addresses various issues that are hampering the advancement of Indian herbal medicine around the globe; these include quality concerns and quality control, pharmacovigilance, scientific investigation and validation, IPR and biopiracy, and the challenge that various indigenous systems of medicine are at risk of being lost. The book also explores the role of traditional medicine in providing new functional leads and modern approaches that can offer elegant strategies for facilitating the drug discovery process. The book also provides in-depth information on various traditional medicinal systems in India and discusses their medical importance. India has a very long history of safely using many herbal drugs. Folk medicine is also a key source of medical knowledge and plays a vital role in maintaining health in rural and remote areas. Despite its importance, this form of medicine largely remains under-investigated. Out of all the traditional medicinal systems used worldwide, Indian traditional medicine holds a unique position, as it has continued to deliver healthcare throughout the Asian subcontinent since ancient times. In addition, traditional medicine has been used to derive advanced techniques and investigate many modern drugs. Given the scope of its coverage, the book offers a valuable resource for scientists and researchers exploring traditional and herbal medicine, as well as graduate students in courses on traditional medicine, herbal medicine and pharmacy.

This authoritative and comprehensive handbook is the definitive work on the current state of the art of Biometric Presentation Attack Detection (PAD) – also known as Biometric Anti-Spoofing. Building on the success of the previous, pioneering edition, this thoroughly updated second edition has been considerably expanded to provide even greater coverage of PAD methods, spanning biometrics systems based on face, fingerprint, iris, voice, vein, and signature recognition. New material is also included on major PAD competitions, important databases for research, and on the impact of recent international legislation. Valuable insights are supplied by a selection of leading experts in the field, complete with results from reproducible research, supported by source code and further information available at an associated website.Topics and features: reviews the latest developments in PAD for fingerprint biometrics, covering optical coherence tomography (OCT) technology, and issues of interoperability; examines methods for PAD in iris recognition systems, and the application of stimulated pupillary light reflex for this purpose; discusses advancements in PAD methods for face recognition-based biometrics, such as research on 3D facial masks and remote photoplethysmography (rPPG); presents a survey of PAD for automatic speaker recognition (ASV), including the use of convolutional neural networks (CNNs), and an overview of relevant databases; describes the results yielded by key competitions on fingerprint liveness detection, iris liveness detection, and software-based face anti-spoofing; provides analyses of PAD in fingervein recognition, online handwritten signature verification, and in biometric technologies on mobile devicesincludes coverage of international standards, the E.U. PSDII and GDPR directives, and on different perspectives on presentation attack evaluation.This text/reference is essential reading for anyone involved in biometric identity verification, be they students, researchers, practitioners, engineers, or technology consultants. Those new to the field will also benefit from a number of introductory chapters, outlining the basics for the most important biometrics.

This book conveys many significant messages for the food engineering and allied professions: the importance of working in multidisciplinary teams, the relevance of developing food engineering based on well-established principles, the benefits of developing the field by bringing together experts from industry, academia and government, and the unparalleled advantage of working as globally as possible in the understanding, development, and applications of food engineering principles. I am delighted to welcome this book to the Series and I am convinced colleagues from all parts of the world will gain great value from it.

Infectious Diseases and Antimicrobial Stewardship in Critical Care Medicine 4E has been fully updated and revised. The clinical diagnostic approach to common infectious disease problems in the CCU is the underlying theme in the book. Emphasized throughout is the importance of formulating an accurate early presumptive clinical syndromic diagnosis which is the basis for selecting optimal initial antimicrobial therapy in the CCU. Without an accurate presumptive clinical diagnosis, effective therapy is unlikely at best. Based on the most probable clinical diagnosis, optimal antibiotic empiric therapy, based on antimicrobial stewardship principles, minimizes resistance and antibiotic complications in the CCU. This new edition features chapters that explain the tenets of differential diagnostic reasoning, differential diagnostic characteristics of fever patterns in the CCU. The proper interpretation of rapid diagnostic tests, in the appropriate clinical context, is included. The diagnostic importance of cardinal clinical findings, particularly when combined, in the appropriate clinical context is emphasized and remains the basis for clinical problem solving in the CCU. Uniquely, critical diagnostic physical findings in the CCU, including color atlas of diagnostic eye findings, are included as important diagnostic determinants in the CCU. Written by infectious disease clinicians for CCU consultants, Infectious Diseases and Antimicrobial Stewardship in Critical Care Medicine 4E remains a useful evidence based and experience tempered key clinical resource for infectious disease problems in the CCU.Key Features Essentials of the tenets of clinical diagnostic reasoning is explained as it relates to formulating a rapid and accurate clinical syndromic diagnosis in the CCU The diagnostic significance of fever patterns and their relationship to the pulse rate in the proper clinical context is explained in depth as related to the CCU setting Formulating an accurate early clinical syndromic diagnosis is presented as essential since it is the basis of effective empiric antibiotic therapy in the CCU How to combine key non-specific laboratory and imaging findings to increase diagnostic specificity and diagnostic probability in the CCU is presented Clinical perspective on the proper interpretation of the clinical significance of rapid diagnostic test results in the CCU is included A clinical approach to apparent'antibiotic failure'in the CCU is presented either due to actual antibiotic failure or seeming but unrelated non-antibiotic failure Section focuses on the practical aspects of antimicrobial stewardship particularly as related to optimizing dosing effectiveness while minimizing resistance and adverse effects in the CCU

This reference work provides comprehensive information about the bioactive molecules presented in our daily food and their effect on the physical and mental state of our body. Although the concept of functional food is new, the consumption of selected food to attain a specific effect existed already in ancient civilizations, namely of China and India. Consumers are now more attentive to food quality, safety and health benefits, and the food industry is led to develop processed- and packaged-food, particularly in terms of calories, quality, nutritional value and bioactive molecules. This book covers the entire range of bioactive molecules presented in daily food, such as carbohydrates, proteins, lipids, isoflavonoids, carotenoids, vitamin C, polyphenols, bioactive molecules presented in wine, beer and cider. Concepts like French paradox, Mediterranean diet, healthy diet of eating fruits and vegetables, vegan and vegetarian diet, functional foods are described with suitable casestudies. Readers will also discover a very timely compilation of methods for bioactive molecules analysis. Written by highly renowned scientists of the field, this reference work appeals to a wide readership, from graduate students, scholars, researchers in the field of botany, agriculture, pharmacy, biotechnology and food industry to those involved in manufacturing, processing and marketing of value-added food products.