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This book comprehensively covers application of salvage therapy in reccurrent prostate cancer. Chapters focus on specific issues associated with a range of surgical and oncological management techniques and strategies including hormone therapy, lymphnode dissection, robotic prostatectomy and salvage reirradiation after locoregional failure. Learning objectives, and definitions of keywords are provided to aid the reader develop a thorough understanding of the topic and reinforce the key points covered in each chapter. Salvage Therapy for Prostate Cancer provides a detailed practically applicable guide on how salvage therapy can be utilised in the treatment of prostate cancer. It represents a valuable resource for trainee and practicing urologists, oncologists, and specialist nurses.

Radical Prostatectomy: Surgical Perspectives provides surgeons with a comprehensive overview of the anatomical approach to radical prostatectomy, whether done through an open (retropubic) or robotic-assisted laparoscopic approach. All chapters are structured to provide a step-by-step approach to the most technically demanding and most common oncologic procedure in urology surgery. The book includes highly practical presentations of typical surgical patients seen in the clinical practice of urology and relies heavily on illustrations and intraoperative photographs to clearly complement the text. In addition, the book includes a detailed description of the management of uncommon but potentially serious intraoperative complications, including major vascular injury, ureteral transaction, and rectotomy.Written by authors from a variety of integrated disciplines, including anesthesia, cardiology, and nursing Radical Prostatectomy: Surgical Perspectives is a unique and valuable resource in the field of urology both for those currently in training and for those already in surgical practices.

In many centers of excellence in Urology, robotic prostatectomy has become the first choice for the surgical treatment of localized prostate cancer owing to benefits such as reduced pain and minimization of impotence and incontinence. This atlas, specifically designed for use by surgeons, provides a beautifully illustrated, step-by-step guide to all aspects of the procedure. The various techniques that can be employed to achieve excellent oncological and functional results are carefully depicted in appropriate detail; for example, nerve-sparing techniques, bladder neck reconstruction, and approaches aimed at the early restoration of continence are clearly described. Special situations, such as prior prostate surgery, a large prostate, and salvage prostatectomy, are also fully covered. The information contained in this atlas will be of great value in enabling surgeons to improve their results and to take full advantage of the benefits of robotic prostatectomy compared with open prostatectomy.

The American Cancer Society anticipates that during 1995, 244000 new cases of cancer of the prostate will have been diagnosed in the United States, with 40400 deaths from the disease process. The rapid increase in the actual number of new cases in the United States is directly related to more regularized digital rectal examinations and the more frequent and widespread use of prostate-specific antigen (PSA) screening programs. As a conse­ quence, major controversies have emerged in how best to manage the patient with cancer of the prostate. These include the necessity of PSA screening programs, how to interpret PSA values, what imaging studies are most appropriate for definition of the true extent of the disease process, the value of pretreatment surgical staging of the disease process, and the value of different treatments. The latter encompass a wide range of options: observa­ tion, radical prostatectomy, the Walsh-type prostatectomy procedure, definitive external beam radiation therapy, local interstitial implantation using iodine-125, iridium-l92, or palladium-103, orchiectomy, cryosurgery, hyperthermia, and various antitestosterone agents such as estrogens or LH,RH agonists. The present volume deals with the major parameters of controversy with regard to cancer of the prostate and will enable the reader to acquire a better understanding of the disease and how best it might be managed to achieve an optimal outcome with a minimum of complications.

Treatment strategies in prostate cancer underlie a permanent change due to continuous improvements. Based on the 10th International Symposium on Special Aspects of Radiotherapy held in Berlin in 2006, this volume highlights key advances in surgical, radiooncological and systemic treatment standards for prostate cancer. Furthermore, interdisciplinary co-operations and controversies are presented and future developments are discussed. The four parts of the book cover the different stages of the disease - localized prostate cancer, the lymph node positive situation, biochemical recurrence, and hormone-refractory and metastatic prostate cancer. Special attention is given to the value and sequence of systemic treatment options in relation to surgery and radiotherapy. Proving the reader with the latest treatment standards of prostate cancer, this book will be of great value to urologists and radiation oncologists as well as to all others involved in the care of patients with prostate cancer.

Radical prostatectomy involves the surgical removal of the entire prostate gland and the seminal vesicles. Recently the open operation has been challenged by laparoscopic and robotic techniques. However, making the transition to this new technology is not an easy option. Avoiding surgical complications such as incontinence and ensuring continued er

Endoscopic/ laparoscopic extraperitoneal radical prostatectomy (EERPE) has become established as a therapeutic option for localized prostate cancer. This book is an atlas, not a conventional textbook. Its main goal is to guide the urologist step by step through EERPE, aiming to make this highly standardized technique reproducible. Every stage of the procedure is presented with numerous endoscopic images and diagrams so that the reader can fully comprehend the different surgical steps. Complications and their management are described in detail. Special chapters are devoted to the anatomy of the prostate, anesthesiological considerations, and postoperative management and training.

Although much progress has been made in the four years since the first edition of Management of Prostate Cancer, prostate cancer remains a significant biological, me- cal, and personal challenge for millions of men. In this interval, some important trends and observations have emerged that represent real progress in the field and which will shape the direction of clinical practice and research in the next 5–10 years. These obs- vations include: (1) a decline in prostate-related cancer mortality in the United States, likely owing to a combination of factors including screening, more aggressive and earlier therapy, and improvements in specific therapies; (2) a significant downward pathological stage migration, so that an individual's chance of cure for a given stage, grade, and PSA is better now than it was early in the PSA era, even without associated improvements in individual therapies; (3) the recognition of new PSA isoforms that may refine screening strategies; (4) several randomized, phase III clinical trials demonstrating survival adv- tages of one form of therapy over another in selected populations (external beam rad- therapy with adjuvant hormones vs radiotherapy alone, radical prostatectomy vs observation); (5) a focus on the biology of bone and bone metastasis, and new agents that reduce skeletal-related events and which may inhibit the growth of new metastases; (6) second-generation anti-PSMA antibodies with improved potential for imaging and therapy; (7) the development and widespread adoption of nomograms that assist in cli- cal decision-making for individual patients; (8) the identification of new genes that