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Dieses Buch stellt praxisrelevante Aspekte des Spezialgebietes'Gerinnung'einschließlich Diagnostik und Therapie von Gerinnungsstörungen für die neurologische Intensiv- und Notfallmedizin dar. Im Fokus stehen Gerinnungsstörungen als Ursache zerebraler Ischämien und intrakranieller Blutungen sowie die Thromboseprophylaxe bei neurologischen Patienten und die Differenzialtherapie mit Antithrombotika in der Neurologie.

Nickel-Titanium alloys are smart materials exhibiting unique properties such as superelasticity and shape-memory effect. The material has been used as orthodontic wires in the dental field for over 20 years. This book is a comprehensive overview to the field of Ni-Ti Materials and the physical, chemical and mechanical properties of this versatile alloy. In addition, complications and challenges exhibited in applications are also discussed.

Dieses Buch informiert über die Prinzipien der manuellen und automatischen Blutbildbestimmung, Anfertigung und Färbung hämatologischer Präparate sowie über deren Interpretation. Die deutschsprachige Neuauflage des englischen Klassikers'Blood Cells'enthält Verweise auf moderne komplementäre Untersuchungstechniken, wie Durchflusszytometrie, Zyto-oder Molekulargenetik. 400 Farbabbildungen illustrieren grundlegende methodische Aspekte, häufige Befunde und seltene Konstellationen. Die Autoren legen großen Wert darauf, stets den klinischen Kontext der Laboruntersuchungen hervorzuheben.

The global medical process is a chain of different medical multidisciplinary procedures. The success in global Patient Safety will depend on the Safety of the consecutive medical processes that intervene in this complex system. Laboratory data is an essential part of health care, indeed it is used in 70% of clinical decisions. Inappropriate laboratory test over requesting is extremely frequent. The prevalence of under requesting has been less studied. The consequences of under requesting are clear, we are missing a diagnosis. Inappropriate over requesting can result not only in a problem of cost but also in a problem regarding patient safety. Additionally, another important consequence of inappropriate tests over requesting is that such amount of unnecessary tests has probably contributed to a significant increase in the volume of those over the last years. In all, there is general consensus that the inadequacy of test requesting must be corrected through strategies and monitored over time through indicators to assure the optimal laboratory contribution to clinical decision-making and patient safety.

The preanalytical phase is an important component of Laboratory medicine and errors arising in this phase affect the validity of laboratory results. In this book physicians and clinical staff have access to valuable information about the current preanalytical variables and factors (patient preparation, sample collection, handling and processing before analysis).

This book is the 2nd improved and expanded edition of'Clinical Enzymology'(Lott/Wolf, 1987). It includes case studies and guidelines for specialists of laboratory medicine and clinicians, devotes each chapter to a specific enzyme or protein marker, contains case studies and guidelines, a section on marker biochemistry and physiology as well as a section on special pathology and analysis. The clear, didactic structure and the multiple choice questions also make the book valuable reading for graduate students in the fields of clinical pathology and laboratory medicine.

Abnormal placental adhesive disorders are associated to massive hemorrhage and high maternal morbidity and mortality. The main risk factor for abnormal invasive placentation is the repeated cesarean, although other factors were identified. There are specific techniques to provide a high confidence diagnosis. However, precise skills must be acquired to recognize detailed diagnostic signs, to avoid common technical mistakes, and also to know when, how and why it is necessary to use each of them. Presurgical study provides diagnosis, extension and compromise of neighboring structures such as the bladder or the parametrium. Knowledge of placental invasion extension is needed to plan any resective surgery such as hysterectomy or one-step conservative surgery. Due to the fact that topography of the invaded area has direct relation with the specific arterial pedicles, a map of the invasion is required to know which type of proximal vascular control can be more effective. Leaving the placenta in situ seems to be the best option when resources or a skilled team are not available, but it requires intensive postoperative controls to detect infection, bleeding or coagulation disorders. Hysterectomy can be an easy solution for non-experimented operators; however, it is usually a very complicated procedure with demonstrated morbidity and mortality due to hemodynamic and hemostatic problems. This book gathers the latest knowledge in relation with the etiology, diagnosis, treatment and also the authors personal experience in more than 500 cases. All aspects of this condition have been analyzed to provide an accurate management, which includes vascular control, urology, anesthesia and hemodynamic management among others.

Defined as red blood cell break down and the release of hemoglobin and intracellular contents into the plasma, hemolysis can seriously impact patient care as well as the laboratory's reputation through its affect on test results. Therefore, the European Preanalytical Scientific Committee, in collaboration with the International Federation of Clinical Chemistry Working Group on Patient Safety, have designed a questionnaire to collect data on prevalence and management of hemolytic specimens referred to the clinical laboratories for clinical chemistry testing. This book will help identify the areas where hemolysis occurs most frequently, which can, in turn, guide further analysis about why it is occurring. Once these elements are known, practices and procedures can be implemented to dramatically reduce hemolysis and avoid erroneous laboratory results affecting patient care and increasing laboratory costs.

No detailed description available for'Theory of Nonlinear Operators'.