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The second volume of the book Emerging Human Viral Diseases discusses pathogenesis, diagnostics, and therapeutic strategies against viral encephalitis, gastroenteritis, and human immunodeficiency viral infections. The chapters discuss symptoms, diagnostics, and preventive strategies against viral infections. The book also reviews the epidemiology and evolution of viruses causing these infections. It also examines symptoms and strategies for developing novel diagnostics and the vaccine against these viruses. Toward the end, it discusses various biosafety principles for handling emerging viruses and reviews various bioinformatics tools and databases in virology research. This timely book offers valuable resource for the scientists working in the field of emerging viral infections and those involved in preventing, controlling, and managing viral diseases. Inclusively this book will be valuable guide covering most recent scientific progress in emerging human viral diseases and management and will serve as the best resource for undergraduates, graduates, medical professionals, researchers, public health physicians, and national and international health authorities.

This book provides a detailed overview of mosquitoes. It covers aspects of their origin, evolution, morphology, diversity, biology, and host finding and recognition. It also describes the behavior and rhythmicity of mosquitoes, their abiotic and biotic interactions, disease vectors and mechanism of disease transmission. Chapters describe mosquito-borne human diseases, mosquito-borne veterinary diseases, and management of mosquitoes. This book provides the readers with both the positive as well as the negative aspects of mosquitoes. It also discusses their use in research as a model organism and development of micro needles and their role in crop pollination. This book is useful for the students studying entomology, public health, medical and veterinary sciences, and applied life sciences. It is also a reference for those working in policy planning and vector management.

This volume covers recent developments on the role, composition, and functional significance of intercellular and interorganellar transfer. It highlights the involvement of intercellular and interorganellar transfer in cell and developmental biology, differentiation, pathogen dissemination, shaping the genetic makeup of organisms, and the development of various diseases. Animals and plants evolved different communication mechanisms and transfer of molecules and organelles between cells and between organelles within the individual cells. Tunneling nanotubes (TNTs) in animals, discovered as recently as 2004, and their functional equivalent in plants, plasmodesmata, discovered over 100 years ago, are the membranous bridges that mediate the transfer of organelles, membrane patches, vesicles, DNA/RNA, and different molecules between cells. In addition, there are other means of transfer and communication between the cells, such as cytonemes, airinames, extracellular vesicles (exosomes), and others. Variations in cytoskeletal composition, morphology, modality, and connected cells suggest that these structures play a role in development, establishment of cell fate, progenitor cell differentiation, cell reprogramming, ferroptosis, generation of cancer stem cells, and various diseases. The exchange of intact membrane patches (trogocytosis) between cells of the immune system may modify the immune response. Additionally, the transfer of genetic information between nucleus and organelles and cells of different species can shape the species and evolutionary outcome. Viral and bacterial pathogens can hijack the inter-cellular transfer routes to spread more efficiently. Cell-to-cell transfer of animal and plant pathogens can also occur by the virological synapse (VS). These specialized pathogen-induced structures share similarities and differences with neurological and immunological synapses.

This book presents a unique overview of significant disparities in health, which exist within complex and multifaceted contexts across different regions. In the twenty-first century, global health inequity presents substantial health challenges, encompassing diverse and interconnected ramifications across socioeconomic, cultural, and political dimensions. Additionally, it thoroughly explores the interconnected and multifaceted underlying factors that are widespread in developing nations. The book puts forth essential and comprehensive recommendations that call for collaborative efforts at multiple levels, including global, national, and local, to identify and address issues effectively.

Science-fiction author William Gibson is famously quoted as saying, “The future is already here – it's just not very evenly distributed.” During the Covid pandemic, telehealth and remote monitoring were elevated from interesting innovations to essential tools in many healthcare systems, but not all countries had the infrastructure necessary to pivot quickly, amply demonstrating the negative consequences of the digital divide. This book presents the proceedings of MedInfo 2023, the 19th World Congress on Medical and Health Informatics, held from 8 – 12 July 2023 in Sydney, Australia. This series of biennial conferences provides a platform for the discussion of applied approaches to data, information, knowledge, and wisdom in health and wellness. The theme and title of MedInfo 2023 was The Future is Accessible, but the digital divide is a major concern for health and care-informatics professionals, whether because of global economic disparities, digital literacy gaps, or limited access to reliable information about health. A total of 935 submissions were received for the conference, of which 228 full papers, 43 student papers and 117 posters were accepted following a thorough peer-review process involving 279 reviewers. Topics covered include: information and knowledge management; quality, safety and outcomes; health data science; human, organizational and social aspects; and global health informatics. Significant advances in artificial intelligence, machine learning, augmented reality, virtual reality, and genomics hold great hope for future healthcare planning, delivery, management, education, evaluation, and research, and this book will be of interest to all those working to not only exploit the benefits of these technologies, but also to identify ways to overcome their associated challenges.

Clinical Laboratory Management Apply the principles of management in a clinical setting with this vital guide Clinical Laboratory Management, Third Edition, edited by an esteemed team of professionals under the guidance of editor-in-chief Lynne S. Garcia, is a comprehensive and essential reference for managing the complexities of the modern clinical laboratory. This newly updated and reorganized edition addresses the fast-changing landscape of laboratory management, presenting both foundational insights and innovative strategies. Topics covered include: an introduction to the basics of clinical laboratory management, the regulatory landscape, and evolving practices in the modern healthcare environment the essence of managerial leadership, with insights into employee needs and motivation, effective communication, and personnel management, including the lack of qualified position applicants, burnout, and more financial management, budgeting, and strategic planning, including outreach up-to-date resources for laboratory coding, reimbursement, and compliance, reflecting current requirements, standards, and challenges benchmarking methods to define and measure success the importance of test utilization and clinical relevance future trends in pathology and laboratory science, including developments in test systems, human resources and workforce development, and future directions in laboratory instrumentation and information technology an entirely new section devoted to pandemic planning, collaboration, and response, lessons learned from COVID-19, and a look towards the future of laboratory preparedness This indispensable edition of Clinical Laboratory Management not only meets the needs of today's clinical laboratories but anticipates the future, making it a must-have resource for laboratory professionals, managers, and students. Get your copy today, and equip yourself with the tools, strategies, and insights to excel in the complex and ever-changing world of the clinical laboratory.

CRISPR is a crucial technology in plant physiology and molecular biology resulting in more sustainable agricultural practices, including outcomes of better plant stress tolerance and crop improvement. CRISPR and Plant Functional Genomics explores ways to release the potential of plant functional genomics, one of the prevailing topics in plant biology and a critical technology for speed and precision crop breeding. This book presents achievements in plant functional genomics and features information on diverse applications using the emerging CRISPR-based genome editing technologies producing high-yield, disease-resistant, and climate-smart crops. It also includes theories on organizing strategies for upgrading the CRISPR system to increase efficiency, avoid off-target effects, and produce transgene-free edited crops.Features: Presents CRISPR-based technologies, releasing the potential of plant functional genomics Provides methods and applications of CRISPR/Cas-based plant genome editing technologies Summarizes achievements of speed and precision crop breeding using CRISPR-based technologies Illustrates strategies to upgrade the CRISPR system Supports the UN's sustainable development goals to develop future climate-resilient crops CRISPR and Plant Functional Genomics provides extensive knowledge of CRISPR-based technologies and plant functional genomics, and is an ideal reference for researchers, graduate students, and practitioners in the field of plant sciences as well as agronomy and agriculture.

Recent Advances in Organometallic Chemistry: Synthetic, Mechanistic and Medicinal Perspective highlights recent advancements in the field of organometallic chemistry. Containing essential information for researchers and advanced-level students, especially those working in chemical synthesis, the book describes the role of organometallic compounds in different combinations in organic synthesis and pharmaceuticals as well as discussing spectral, magnetic and sensing features of the compounds. Including the role of computational investigations towards the mechanistic study of biomimic complexes in catalytic transformation reactions, the book provides a large number of examples along with their leading applications in other fields.Each chapter covers basic strategies, which are illustrated along with examples of the latest advancements in the field and in-depth explanations. Covers the basics of bonding, synthesis and properties of organometallic compounds Includes the role of computational chemistry and magnetochemistry Features recent developments with examples and applications

The new edition of this unique resource, grounded on an understanding that our global world is more connected than it has ever been, provides an essential survey of infectious diseases based on both clinical presentation and geographical area of exposure.This book is split into three main sections. The first section offers an overview of the geopolitics of infectious diseases, highlighting the channels through which a disease can spread from one region or country to another, including air travel, shipping or migration. The second section provides a comprehensive overview of each region, highlighting the infectious diseases common to that part of the world. The final section includes a chapter examining new infections of concern, and a chapter discussing infectious diseases in the context of global climate change.Thoroughly updated with the latest clinical data and featuring contributions from leading scholars and clinicians in the field, this book is a timely and important resource for practitioners and scholars across Clinical Medicine, Epidemiology and Public Health.

This textbook covers broad topics within the application of natural language processing (NLP) in biomedicine, and provides in-depth review of the NLP solutions that reveal information embedded in biomedical text. The need for biomedical NLP research and development has grown rapidly in the past two decades as an important field in cognitive informatics. Natural Language Processing in Biomedicine: A Practical Guide introduces the history of the biomedical NLP field and takes the reader through the basic aspects of NLP including different levels of linguistic information and widely used machine learning and deep learning algorithms. The book details common biomedical NLP tasks, such as named entity recognition, concept normalization, relation extraction, text classification, information retrieval, and question answering. The book illustrates the tasks with real-life use cases and introduces real-world datasets, novel machine learning and deep learning algorithms, and large language models. Relevant resources for corpora and medical terminologies are also introduced. The final chapters are devoted to discussing applications of biomedical NLP in healthcare and life sciences. This textbook therefore represents essential reading for students in biomedical informatics programs, as well as for professionals who are conducting research or building biomedical NLP systems.

This book provides the latest information on trans-Himalayan Hindu Kush Region (HKR) fisheries including the Indian Himalayan Region (IHR) as well as the historical context of its sustainable development for improving livelihood and nutritional security. The book serves as an important document to provide knowledge and information about the major concerns of environmental and anthropogenic factors that have impacted the population of certain important fishes in the ecosystem and the strategies and policies required for the conservation of these important groups of fishes, viz., Mahseer, snow trout, minor carp, catfishes, etc. The chapters describe the information to the readers on potential cold water and cool water fish species suitable for large-scale farming and propagation addressing the issues of diseases, nutrigenomics, and nanobiotechnology. This book also addresses the prospects and potential of recreational fishing in India and the scope for its improvement to generate more employment and income citing the success stories and primary information from reputed anglers. Finally, the book also elucidates a comprehensive yet representative description of many challenges associated with inland coldwater- cool water fisheries and aquaculture in HKR, IHR, and its way forward.

This edited volume is an inclusive collection of information on crop holobiome, their function and diversity, the plausible role of soil microbes in crop growth, protection from pathogens and stresses, the use of resilient microbiomes for changing climate, and the use of new technologies to study plant-insect-microbe molecular interactions in agricultural systems. Holobiomes provide information about both plants and their microbiomes, which gives a more comprehensive insight, particularly for changing climatic scenarios. By optimizing the crop holobime function crop productivity and plant health can be enhanced manifold. This book deep dives into the numerous ways in which holobiome supports the improving plant health, nutrient uptake, disease control, and stress resistance in major food crops. It helps researchers, academicians, agri-entrepreneurs, and technologists understand the structure and function of holobiomes in crop growth, health, stress tolerance under climatic changes, and holobiome diversity and evolution. The book is also helpful in designing new dimensions in the holobiome research and development of new products and technologies. This volume is of interest and useful to agriculture scientists, microbiologists, ecologists, and is a valuable source of reference to researchers and students.

Modernizing Global Health Security to Prevent, Detect, and Respond explores—through thoughtful, thorough, and diverse scientific review and analyses—factors that have led to recent public health emergencies and offers a vision for a better protected global environment. The authors consider the history of global health security, governance, and legal structures with an eye toward novel approaches for the present and future. The book presents a vision for a more protected and safer global public health future (with the actions needed to achieve it) to prevent, detect, and respond to (re)emerging threats. Its aim is to chart a way forward with the understanding that future pandemics must and can be prevented. Major topics examined from a public health perspective include global health security; the growing concept of One Health; epidemic and pandemic prevention, detection, and response; reviews of past (e.g., Ebola, MERS-CoV, Zika, and COVID-19) public health emergencies of international concern; roles of information and communication technology; humanmade public health threats; and legal and ethical issues (e.g., viral sovereignty, trust, and transparency). Modernizing Global Health Security to Prevent, Detect, and Respond provides the academic substance and quality for researchers and practitioners to deeply understand the why of health emergencies, and most importantly—what we can and should do now to prepare.Highlights (re)emerging past and future threats to public health (e.g., climate change, antibiotic resistance, failures of societal sectors to work together)Discusses new visions for global health security in each chapterConsiders how to leverage technological innovations to advance public healthIncludes practical examples through case studies from around the world

This proposed book aims to present an analysis of several crisis issues induced by global climate changes and implications at the micro-level, particularly from the perspective of ground-based study. Climate crisis leads to several socio-ecological issues which need to discuss with some empirical case studies from the contextual global evidences. Climatic crisis generates several social responses which are associated with mitigating issues in addition to sustainable development goals. Under these circumstances, several loopholes interlinked with climatic crisis need to expose in the present-day context. This book argues that it is important to understand the issues from multiple dimensions. It identifies some important dimensions to discuss in the process. Themes we purpose to cover are: several field-based studies are included for which micro-level field-based data would incorporate to understand current crisis induced by climate change, thus exposing the vulnerabilities of the communities which would be incorporated in different chapters with adequate representation of qualitative methods, modelling-based geospatial approach. Therefore, some secondary data-based studies have also been included to provide a broader picture. Additionally, this book aims to provide an interdisciplinary understanding of the issues mainly from the lenses of Geography, Economics, and Sociology as well as Environmental Studies too. Given the focus of this study, it is believed that an approach that harmonizes the cognitive domain from different discipline is appropriated. A combination of chapters using qualitative as well as quantitative methods also made this book exclusive from others. We believe that this edited book surely contributes the knowledge domain with some relevant chapters'discussion in the contemporary time and leads to reduce the gap of knowledge.

This book provides essential information on the epidemiology, diagnosis and management of common and some rare infections in travellers. It will equip readers with key knowledge on clinically important emerging and re-emerging infections caused by wide variety of bacteria, viruses and parasites. The coverage ranges from influenza, hepatitis, malaria and tuberculosis to Ebola virus disease, Lassa fever, Crimean Congo haemorrhagic fever, dengue, Zika virus infection and many other important diseases. The emergence and spread of antimicrobial-resistant microorganisms is discussed, and practical advice is included regarding disease prevention in travellers and humanitarian aid workers. Other generic chapters address the clinical approach to fever in the returning traveller, and preparedness and response to emerging infectious diseases. This comprehensive, up-to-date book will be an excellent source of information and guidance for all clinicians and researchers with an interest in infectious diseases, microbiology, epidemiology, and travel medicine.

This book explores the medical importance of Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter spp. (ESKAPE) pathogens, and the challenges posed by antibiotic resistance. It covers the antibiotic resistance profile and detection of ESKAPE pathogens, as well as the mechanistic understanding of antibiotic resistance in these pathogens. The book discusses standard microbiological techniques, including staining, morphological and cultural characteristics, biochemical properties, and serotyping, as well as nucleic acid amplification and molecular diagnostic techniques for the detection of ESKAPE pathogens. In addition, the book explores biochemical, molecular, and computational techniques for the determination of virulence factors of ESKAPE pathogens. It also examines the synthesis, structure, function, and inhibitors of virulence factors and biofilm componentsin these pathogens. The book explores various strategies for combating ESKAPE pathogens, including antibiotic adjuvants and their synergistic activity, phytochemicals as potential antibacterial agents, photodynamic therapy, antimicrobial peptides and antibacterial antibodies, antimicrobial activity of Nanomaterials and Nanocomposites, and bacteriophage therapy. Finally, the book discusses in silico and computational approaches for the inhibition of ESKAPE pathogens. This comprehensive book is of interest to researchers, students, and healthcare professionals interested in the diagnosis, prevention, and treatment of ESKAPE pathogens.

This book describes the theoretical background of the different forms of tinnitus (ringing in the ears) and detailed knowledge of state-of-the-art treatments of tinnitus. Tinnitus has many forms, and the severity ranges widely from being non-problematic to severely affecting a person's daily life. How loud the tinnitus is perceived does not directly relate to how much it distresses the patient. Thus, even tinnitus very close to the hearing threshold can be a disabling symptom. It can reduce the quality of life by generating anxiety and concentration problems, impairing the ability to do intellectual work, making it difficult to sleep, causing depression and sometimes even leading to suicide.Textbook of Tinnitus has filled a void by providing a comprehensive overview about the different forms of tinnitus, their pathophysiology and their treatment. However, since the publication of the first edition of the Textbook of Tinnitus in 2011, tinnitus research has dramaticallyevolved. In view of the substantial increase in knowledge, most chapters in this second edition are newly written and a few original chapters have had major updates. This edition has nine sections, covering the basics of tinnitus, the neurobiology of tinnitus, pathophysiological models, animal research, diagnosis and assessment, various forms of management and treatment, and finally, a look at the future of tinnitus and tinnitus research. The book will be of great interest to otolaryngologists, neurologists, psychiatrists, neurosurgeons, primary care clinicians, audiologists and psychologists, and students. Because of its organization and its extensive subject index, Textbook of Tinnitus, Second Edition can also serve as a reference for clinicians who do not treat tinnitus patients routinely.

'This book illustrates the current state of surgical treatment of lymphedema, including diagnostics, conservative treatment, postsurgical treatment, and research. It is an optimal guide for those who want to become experts in lymphatic disease and its treatment.'Isao KoshimaThe first edition of Modern Surgical Management of Chronic Lymphedema, edited by Yves Harder, Christoph Hirche, Katrin Seidenstücker, and Moustapha Hamdi, has been conceived and written by enthusiasts for lymphatic surgery who have dedicated their professional careers to treating patients suffering from this chronic disease.Featuring current perspectives and particularities of surgical lymphedema treatment with contributions from international experts in the field, this innovative book describes evidence-based, multi-disciplinary approaches to treating chronic lymphedema from the point of view of clinical experts. It is also a comprehensive companion for multi-professional specialists looking for an erudite understanding of the complex treatment of lymphedema.Ultimately, the book seeks to advance the contemporary understanding that underpins the philosophy and general principles of modern surgical management of chronic lymphedema, in order to improve the quality of life of patients.Key highlights:Firsthand clinical pearls for treating lymphedema patients and managing the often-chronic issues that significantly impact on daily quality of lifeGeneral focus on the fields of embryology, anatomy, physiology, and pathophysiology of the lymphatic systemSpecial focus on diagnosis, evaluation, and complete decongestive therapy (CDT)Step-by-step descriptions of the surgical corner-stones, including lymphovenous anastomosis (LVA), vascularized lymph node transfer (VLNT), and alternative supermicrosurgical techniques, as well as reductive and lymphoablative surgeryUnique contributions on the diagnosis and treatment of lymphatic filariasisBasic concepts of experimental research in the fieldEvidence- and expert-based algorithm for personalized and stage-dependent treatmentOver 70 full-color and highly instructive illustrations and more than 250 clinical imagesThis is a valuable and practical resource for surgeons of various clinical fields with supermicrosurgical expertise, lymphologists and angiologists, general practitioners, psychologists, lymphedema therapists, dietitians, specialized nurses, as well as medical students.

This open access book gathers selected high-quality research papers presented at the Ninth International Congress on Information and Communication Technology, held in London, on February 19–22, 2024. It discusses emerging topics pertaining to information and communication technology (ICT) for managerial applications, e-governance, e-agriculture, e-education and computing technologies, the Internet of Things (IoT), and e-mining. Written by respected experts and researchers working on ICT, the book offers an asset for young researchers involved in advanced studies. The work is presented in ten volumes.

This book is a groundbreaking book that delves into the critical intersection of health care and sustainability. As the healthcare industry faces increasing scrutiny regarding its environmental impact, this comprehensive guide offers a roadmap for transforming healthcare systems into sustainable entities that prioritize the health of both individuals and the planet. Drawing on a multidisciplinary approach, the book explores the environmental footprint of healthcare practices and infrastructure, shedding light on the resource consumption, waste generation, and pollution associated with the industry. It establishes the crucial link between environmental health and human health, emphasizing how a polluted environment can impact public health outcomes and the need to preserve natural resources for improved healthcare outcomes. The book goes beyond merely highlighting the challenges; it presents practical strategies and actionable solutions for healthcare professionals, policymakers, and stakeholders to navigate the path toward sustainability. It examines case studies and best practices from healthcare institutions that have successfully implemented sustainable initiatives, showcasing their approaches and lessons learned. In addition to addressing the technical aspects, the book tackles the ethical and social considerations of sustainable health care. It emphasizes the importance of equity, social justice, and community engagement in promoting sustainability within healthcare delivery and decision-making processes. This book is an indispensable resource for healthcare professionals, policymakers, researchers, and students seeking to integrate sustainability practices into their work. It serves as a guide for creating a greener and healthier future, highlighting the potential of sustainable health care to improve both environmental well-being and public health outcomes. With its comprehensive coverage, insightful analysis, and practical recommendations, this book contributes to the global conversation on sustainable health care and provides a solid foundation for transforming the industry. It inspires readers to become catalysts for change, fostering a new era of health care that not only preserves health but also preserves the Earth for future generations.

Artificial Intelligence in Clinical Practice: How AI Technologies Impact Medical Research and Clinics compiles current research on Artificial Intelligence within medical subspecialties, helping practitioners with diagnosis, clinical decision-making, disease prediction, prevention, and the facilitation of precision medicine. The book defines the basic concepts of big data and AI in medicine and highlights current applications, challenges, ethical issues, and biases. Each chapter discusses AI applied to a specific medical subspecialty, including primary care, preventive medicine, general internal medicine, radiology, pathology, infectious disease, gastroenterology, cardiology, hematology, oncology, dermatology, ophthalmology, mental health, neurology, pulmonary, critical care, rheumatology, surgery, and OB-GYN. This is a valuable resource for clinicians, students, researchers and members of medical and biomedical fields who are interested in learning more about artificial intelligence technologies and their applications in medicine. Provides the history and overview of the various modalities of AI and their applications within each field of medicine Discusses current AI-based medical research, including landmark trials within each field of medicine Addresses the current knowledge gaps that clinicians commonly face that prevent the application of AI-based research to clinical practice Encompasses examples of specific cases and discusses challenges and biases associated with AI

This book presents the latest findings in medical entomology in Japan and neighboring Asian countries. It provides an overview of the current issues of medically important arthropods in this region and also refers to the issues that are likely to become more serious in the near future. It helps us understand that addressing the arthropod issues is not enough in limited regions, but requires a coordinated response throughout these regions. Global warming and globalization are affecting both vector and vector-borne diseases, causing rapid changes in their distribution and ecology. From the perspective of global pest control, the book focuses not only on domestic pests in Japan but also on pests in neighboring Asian countries including the Philippines, Thailand, Taiwan, Vietnam, etc., which are geographically and economically close to Japan. Japan has experience of eradicating malaria and lymphatic filariasis, drastically reducing the number of cases of Japanese encephalitis patients, and succeeded in controlling flies in the metropolis of Tokyo. The know-how learned and created from these past successes should provide valuable information for other parts of Asia that are still struggling with pest infestation today. With the growing interest in these issues worldwide, this book provides essential information in medical entomology for researchers, including students and early career researchers. By integrating the latest findings in medical entomology with past successes and experiences in the field, the book is also a valuable reference for many professionals planning sustainable pest control.

This book reviews the recent challenges and future perspectives involved in the wastewater-based epidemiology (WBE) for COVID-19. The book aims to improve the monitoring of COVID-19 in wastewater by focusing on recent scientific studies in the surveillance and treatment of wastewater containing SARS-CoV-RNA, assessment of COVID-19 in the community and delivering a new scientific understanding of prevalence and re-emergence based on the WBE. It also provides a global perspective on effective detection methods for the analysis and interpretation of the RNA count of SARS-CoV-2 virus in wastewater and predicts the effects wastewater may have on the infection rate.Readers will find in this book case studies from France, India and Southeast Asian of non-invasive population-based monitoring of SARS-CoV-2 through sewage surveillance, and will learn more about the virus behaviour and transmission in different environmental settings. The significance of membrane technologies for virusremoval from water is also addressed in this book, as well as advanced techniques for identifying, quantifying, and characterizing SARS-CoV-2 in activated sludge and wastewater. The book provides a great interface to researchers such as microbiologists, environmental engineers, data scientists and civil engineers, emphasizing issues related to the current monitoring methodology. Furthermore, it also encourages researchers and policymakers by raising awareness of potential new methodologies for wastewater surveillance and accurate monitoring of COVID-19.

This book explores the antifungal properties of natural products and reviews their antifungal mechanism. An introductory chapter illustrates the various fungal pathogenic species, common fungal diseases, and general mechanisms of action of various antifungal classes, including natural products. The book comprises seven sections and each section contains chapters on the efficacy and antifungal mode of action of plant extracts, essential oils, natural compounds, their derivatives, and plant-based nanoparticles. A section summarizes the antifungal efficacy of compounds derived from sources other than plants, like microbes. Besides compound toxicity, the book explores the antifungal mode of action and efficacy against the virulence and pathogenicity of fungal pathogens like Candida, Aspergillus, Cryptococcus, Histoplasma, and other pathogenic fungi. Further, the book also describes recent advancements in the discovery of novel drug targets and therapeutic strategies that are non-toxic and more efficacious for combating drug resistance. This book is an invaluable source for researchers working in the field of fungal biochemistry, anti-microbial, and anti-bacterial and undergraduate and postgraduate students of microbiology and pharmacology.

Dieses Buch ist eine kompakte klinische Einführung in die Lyme-Borreliose für Ärzte aller Fachrichtungen, die Patienten mit Verdacht auf B. burgdorferi-Infektion betreuen, sei es im Krankenhaus oder in der Allgemeinpraxis. Das Buch bietet viele praxisorientierte Informationen zu Symptomatik, Diagnose, Behandlung und Prophylaxe mit besonderem Schwerpunkt auf der Situation in Europa. Gleichzeitig beschreibt es den aktuellen wissenschaftlichen Kenntnisstand so detailliert, wie es für das Verständnis der pathogenetischen Zusammenhänge und deren Relevanz für die medizinische Versorgung erforderlich ist. Die Autoren sind Mitglieder einer interdisziplinären Expertengruppe von Epidemiologen, Biologen, Mikrobiologen und Klinikern, die seit vielen Jahren auf dem Gebiet der zeckenübertragenen Krankheiten tätig sind. Die persönliche Erfahrung jedes einzelnen Autors, die er durch die tägliche Arbeit mit Patienten in Spezialkliniken oder durch die Konfrontation mit komplizierten Fragen der Grundlagenforschung, Epidemiologie und Labordiagnostik der Lyme-Borreliose gesammelt hat, stellt eine wichtige Stütze des Buches dar. Aus dem Blickwinkel des klinischen Managements und der praktischen Problemlösung geschrieben, wird diese aktuelle Monographie den Kliniker bei der Bewältigung diagnostischer Herausforderungen und der angemessenen medizinischen Versorgung von Patienten mit Lyme-Borreliose unterstützen.

Cyberhate is defined as racist, discriminatory, negationist and violent statements made on social network platforms, text platforms, comment pages, and more. The Handbook on Cyber Hate, the Modern Cyber Evil, includes twenty-seven chapters from scholars representing over fifteen countries from the Global North and the Global South demonstrating a range of multi-faceted perspectives. While providing such a focus, these papers will also operate with a constantly evolving conceptualization of contemporary societies and their modern cyber-evil. Indeed, modern cyber-evil is a global concern and is primarily based on human minds and activities, and on deviant uses of modern technologies, which may differ ideologically, historically and culturally on the global map of modern legal systems. This plurality of perspectives, which poses a challenge to our future, is a strength of this handbook that offers a variety of foundations, legal perspectives, and popular developments in an effort to suggest measures to combat this modern cyber-evil infecting communications around the world. Editors Anne Wagner and Sarah Marusek offer a unique collection of chapters involving the theoretical foundations, legal perspectives, and societal perspectives from popular culture of modern cyber evil in order to address and combat racism on the basis of alleged race, skin color, nationality, descent and national or ethnic origin, etc.; discrimination/xenophobia on the basis of sex, gender, sexual orientation, religious or philosophical beliefs, health status, physical characteristics, etc.; hatred; violence; e-predation; and e-victimization. Advance Praise for “Handbook on Cyber Hate – The Modern Cyber Evil” “In'Handbook on Cyber Hate – The Modern Cyber Evil', editors Anne Wagner and Sarah Marusek have masterfully created a much-needed resource for understanding the complex and ever-changing landscape of online hate and cyberbullying. This comprehensive handbook delves deep into the murky waters of cyberevil, offering insightful semiotic and transdisciplinary perspectives from a wide range of international scholars. Each chapter deftly navigates the theoretical, legal, and societal dimensions of cyberhate, shedding light on the complex interplay between technology, law, and culture. The book's exploration of cyber hate is not just academic, but a call to action. It encourages readers, denizens of the digital semiosphere, to recognize and combat the insidious nature of online hate, equipping them with knowledge and strategies for creating a safer digital world. Covering topics from the study of benign exhibitionism, the boundaries between speech and action in cyberhate, legal intricacies of that speech, trolling in social media and hegemonic masculinity, to the cinematic portrayal of cyberbullying and the malicious use of memes: this handbook is a beacon of hope and guidelines in our increasingly digital society. What sets this handbook apart is its holistic approach. It not only identifies problems, but in many cases inspires solutions, fostering a culture of responsible digital citizenship and empathy. This is not just a book, but a road map for creating a more inclusive and compassionate online community. As we face the challenges of the digital age,'Handbook on Cyber Hate – The Modern Cyber Evil'is an indispensable handbook for researchers, educators, policy makers and all who seek to understand and combat the complexities of cyber hate. This is a must-read for shaping a more respectful and empathetic digital world.” Kristian Bankov, Professor of Semiotics, New Bulgarian University “In the present time of great confusion caused by the blurring of the lines of distinction between the real and virtual worlds, between artificial and human forms of intelligence and even between good and bad technologies representative for expressions of

Carbon nanomaterials have several applications, which is driving up scientific research into them. The book showcases the most recent advancements and research discoveries rather than just providing an overview. Each chapter offers authoritative insights into the ever-changing field of carbon-based nanomaterials, as written by top authorities in their respective domains. The book stands out for its persistent focus on real-world application. It is devoted to practical applications and is divided into four sections. The intriguing promise of carbon nanomaterials, their synthesis, and their possible uses set the stage for the adventure. Subsequently, the emphasis shifts to agriculture, where nanomaterials have been shown to improve plant health, fend against illnesses, promote growth and development, and even help detect and remove herbicides. The biomedical part explores the potential toxicological ramifications of these materials while introducing the reader to their ground-breaking role in drug delivery, tissue engineering, and the fight against fungal diseases. Overall, the book provides valuable insights and serves as a comprehensive resource for researchers and scientists across various interdisciplinary subjects.

This edited book highlights the multifunctional role of the ubiquitous molecule, melatonin in crop plants. The major focus of this edition is to provide a comprehensive insight into the key focus is on Melatonin mediated alleviation of abiotic stresses and pathogens infection. The inception of melatonin as an animal hormone and the subsequent discovery of its multifaceted function in the animal system has revolutionized the research on this penial hormone. During the last decade, the discovery, quantification and functional studies of melatonin as phytohormone has emerged at a rapid pace. Recently, this phyto-protectant has become an integral component of lab and field-based research on the mitigation of adverse effects of climate-driven abiotic stresses and postharvest biology and technology.The book explores melatonin mediated management of various abiotic stresses such as drought, salinity, heat and cold temperature. The book also focuses on role of melatonin in heavy metal stress, viral, bacterial, and fungal diseases, and, also contains chapter on melatonin facilitated nutrient use efficiency in plants. This book is of interest to postharvest industries, horticulturists, scientists, researchers, and students.

While medical specialists in disaster mitigation, preparedness, and response are needed worldwide, the initial phase of disaster response is almost entirely dependent upon local resources—making it essential that all healthcare personnel have a working knowledge of the field and stand ready to integrate into the response system. Ciottone's Disaster Medicine, 3rd Edition, is the most comprehensive reference available to help accomplish these goals in every community. It thoroughly covers isolated domestic events as well as global disasters and humanitarian crises. Dr. Gregory Ciottone and more than 200 worldwide authorities share their knowledge and expertise on the preparation, assessment, and management of both natural and man-made disasters, including lessons learned by the responders to contemporary disasters such as the COVID-19 pandemic, Australian and western U.S. wildfires, European heatwaves, the Beirut explosion, recent hurricanes and typhoons, and the global refugee crisis. Part 1 offers an A-to-Z resource for every aspect of disaster medicine and management, while Part 2 features an exhaustive compilation of every conceivable disaster event, organized to facilitate quick reference in a real-time setting. Covers basic concepts such as identification of risks, organizational preparedness, equipment planning, disaster education and training, and more advanced concepts such as disaster risk reduction, health in complex emergencies, building local disaster resiliency, psychological impact of disasters on children, and more. Contains new decision trees throughout that help guide you through the decision-making process in difficult situations. Uses an easy-to-follow, templated approach to historical perspectives, overviews of current practice including pre-incident and post-incident actions, medical treatment of casualties, and potential pitfalls. Includes updated sections on man-made disasters, including mass casualties, active shooter situations, integrated response to terrorist attacks, and chemical/biological/radiological/nuclear/high-yield explosives disasters. Discusses the latest technologies, such as the use of mobile disaster applications, drone response systems, and virtual reality simulation training. Features thoroughly updated information on crisis leadership, practical applications of disaster epidemiology, disaster and climate change, and the integration of non-government agencies (NGOs) in disaster response—a critical topic for those responding to humanitarian needs overseas. Includes new chapters on Pandemic Preparedness and Response, Disaster Medicine in a Changing Climate, Disaster Response in Asia, Building Local Capacity and Disaster Resiliency, Civilian-Military Coordination in Disaster Response, Medical Simulation in Disaster Preparedness, Disaster Nursing, Crisis Meta-Leadership, Palliative Care in Disasters, Counter-Terrorism Medicine, SARS CoV (COVID-19 and SARS), and Disasters in Space Travel. An eBook version is included with purchase. The eBook allows you to access all of the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud.

This book provides a comprehensive view for plant microbe interactions towards stress management and microbiome-assisted approaches in sustainable agriculture. It is divided into four major sections. The book gives insights into the increasing threat of abiotic and biotic stresses and the accompanying challenges to modern agriculture. Through different chapters, the book shows how various microorganisms could ameliorate abiotic and biotic stress, and contribute towards food sustainability and restore ecosystem functioning. It provides a deep understanding of soil microbiome and its interaction with plants, to enhance food security. It further talks about metagenomic approaches for methodological tool for studying the soil microbiome. Separate sections on stress, talk at length about the various abiotic and biotic stresses that plants are faced it. The book culminates with an exciting section on microbiome-assisted approaches for combating stress. It talks about the different microbiomes such as rhizosphere, soil, phyllosphere and endophytic microbiome. The book would be beneficial to students, researchers and course instructors in microbiology, botany, plant pathology and agriculture.

The International Encyclopedia of Public Health, Third Edition, Five Volume Set is an authoritative and comprehensive guide to the major issues, challenges, methods, and approaches of global public health. Spanning across 5 volumes, 13 subject areas and 480 chapters, this new edition takes a multidisciplinary approach and presents the history, methodology, and latest advances in biomedical research and related scientific fields, including social sciences, life sciences, and bioengineering to address public health research, disease, health processes, and disciplines. The book offers readers evidence-based analysis and information on solutions to real-world problems in global and local health through a multidisciplinary and comprehensive approach.Covering all dimensions of the field, from the details of specific diseases, to the organization of social insurance agencies, the articles included comprise the fundamental research areas of global public health: historical roots, scientific research methodology and approaches, public health of vulnerable population subgroups (the aged, children and adolescents, at-risk populations), environmental and occupational epidemiology, and much more.Includes the most comprehensive, high-level, internationally focused reference work available on public healthPresents an invaluable resource for both researchers familiar with the field and non-experts requiring easy-to-find, relevant, global information and a greater understanding of the wider issuesIncorporates biomedical and health social science issues and perspectivesProvides a comprehensive overview of all aspects of the COVID-19 pandemic Focuses on the dynamic collaboration of many scientific areas for the improvement of healthcare in communities