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Current Topics in iPSCs provides a deep analysis of the underlying fundamentals that support short and mid-term developments and milestones in the business of mesenchymal stem cell therapies. This volume explores the next frontier of MSC therapies and how the transformational potential of therapeutic adult cells will be realised in all therapy areas. The impacts of clinical and economic benefits are dissected throughout each of the chapters. Written by thought leaders in the field for those curious about the interface of science and business. - Explores the strategy at the forefront of the science of mesenchymal stem cells - Provides an overview of all therapy areas where MSC and MSC-derived products can be used therapeutically - Depicts transformational changes in healthcare that enable the implementation of MSC-powered technology platforms

Chapter “Developing a VR Tool to Support Repeat Pattern Design Learning ” is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

This volume gathers select proceedings of the 10th International Conference on Wave Mechanics and Vibrations (WMVC), held in Lisbon, Portugal, on July 4-6, 2022. It covers recent developments and cutting-edge methods in wave mechanics and vibrations applied to a wide range of engineering problems. It presents analytical and computational studies in structural mechanics, seismology and earthquake engineering, mechanical engineering, aeronautics, robotics and nuclear engineering among others. The volume will be of interest for students, researchers, and professionals interested in the wide-ranging applications of wave mechanics and vibrations.

Biofabrication for Orthopedics A comprehensive overview of biofabrication techniques for orthopedics and their novel applications With an ever-increasing global population and the rise in the occurrence of orthopedic diseases amongst an aging population, it is essential for technological advances to meet this growing medical need. Orthopedic biofabrication is a cutting-edge field that seeks to produce novel clinical solutions to this mounting problem, through the incorporation of revolutionary technologies that have the potential to not only transform healthcare, but also provide highly automated and personalized patient solutions. With the advances in the discipline, there is a significant growing interest in biofabrication for orthopedics in research activity geared towards routine clinical use. Ideal for a broad readership amongst medical practitioners and scientists, Biofabrication for Orthopedics summarizes all aspects of the topic: detailed information on the technology, along with advanced developments, research progress, and future perspectives on biofabrication for orthopaedics—particularly on the potential applications for tissue engineering technologies. In doing so, the book describes the various biomaterials—natural and synthetic—use for orthopedics and discusses the many ways in which these materials can be used in all parts of the body. As such, it offers detailed information on a wide range of applications in the fields of biology and clinical and industrial manufacturing. Biofabrication for Orthopedics readers will also find: Insights into the applications of biofabrication technologies in various bodily functions Thorough discussion of different biofabrication techniques used in creating orthopedic products, like stereolithography, cell sheet and organ bioprinting, electrospinning, and microfluidics Discussion of a wide range of diverse functions, such as bone implants, skin regeneration, vascularization, meniscus remodeling, and more Biofabrication for Orthopedics is a useful reference for those in a variety of research fields like medical-related practitioners and scientists, materials science, medicine, and manufacturing, as well as the libraries who support them.

This two-volume set LNCS 12784 and 12785 constitutes the refereed proceedings of the 8th International Conference on Learning and Collaboration Technologies, LCT 2021, held as Part of the 23rd International Conference, HCI International 2021, which took place in July 2021. Due to COVID-19 pandemic the conference was held virtually. The total of 1276 papers and 241 posters included in the 39 HCII 2021 proceedings volumes was carefully reviewed and selected from 5222 submissions. The papers of LCT 2021, Part II, focus on Games and Gamification in Learning; Chatbots in Learning; AR, VR and Robots in Learning.

This book offers to readers a selection of refereed papers that were presented at the Sixth International Symposium on Intelligent Systems Technologies and Applications (ISTA'20). All submissions were evaluated on the basis of their significance, novelty, and technical quality. This book consists of 28 papers (19 regular and 9 short papers) that were virtually presented at the Symposium. The papers cover different areas such as big data analytics, security and privacy, Internet of things, machine and deep learning, health informatics, visual computing, signal processing, and natural language processing. The book is directed to the researchers and scientists engaged in various fields of intelligent systems.

This book presents a concise, clear, and consistent account of the methodology of phase synchronization, an extension of modal analysis to decouple any linear system in real space. It expounds on the novel theory of phase synchronization and presents recent advances, while also providing relevant background on classical decoupling theories that are used in structural analysis. The theory is illustrated with a broad range of examples. The theoretical development is also supplemented by applications to engineering problems. In addition, the methodology is implemented in a MATLAB algorithm which can be used to solve many of the illustrative examples in the book. This book is suited for researchers, practicing engineers, and graduate students in various fields of engineering, mathematics, and physical science.

An In Depth Look at Virtual Reality summarizes research findings relating to virtual reality implementation for pain assessment and treatment, reviewing the literature in pediatric and adult pain care for acute and chronic conditions across several pain populations. The authors provide detailed information about the effect mechanisms of virtual reality for Parkinson's disease, and the virtual reality interventions for rehabilitation of Parkinson's disease in terms of assessment and treatment. Anxiety disorders, such as specific phobia, post-traumatic stress disorder, and social anxiety disorder have garnered the greatest therapeutic attention due to the advantages that applying exposure therapy techniques in a virtual reality environment has over many real-life exposure situations. Later, in order to further improve the intelligence level of a fully mechanized coal mining face and construct a stable and reliable monitoring system of hydraulic support, a monitoring method of hydraulic support in a virtual environment is proposed. In order to further improve the intelligence level of fully mechanized coal mining face and construct a stable and reliable monitoring system of hydraulic support which is of guiding significance to actual production, a monitoring method of hydraulic support in virtual environment is proposed. In the concluding study, using meta-analysis methods and combining the basic elements of teaching system design, a quantitative analysis of 60 quasi-experimental or experimental virtual reality and augmented reality studies is conducted.

This book introduces the latest achievements of Russian scientists regarding the theory and practice of situational control of the SEMS group. It also discusses the development of methods and algorithms for interaction of the SEMS group in situational control, based on the principles of security, flexibility, and adaptability in behavior, as well as parallelism in information processing, computing, and control. Recently, the task of ensuring the functioning of robots in the framework of collective cooperation has become relevant, and the use of the principles of situational management of the SEMS group makes it possible to ensure the efficiency, reliability and safety of real-time operation. The topics covered include, but are not limited to the following: Problems and principles of situation controlMethods and algorithms of situational controlInformation and measuring support of situational control systemsSimulation ofsituation control This book is intended for students, scientists, and engineers specializing in the fields of smart electromechanical systems and robotics.

This two-volume set LNAI 12163 and 12164 constitutes the refereed proceedings of the 21th International Conference on Artificial Intelligence in Education, AIED 2020, held in Ifrane, Morocco, in July 2020.•The 49 full papers presented together with 66 short, 4 industry & innovation, 4 doctoral consortium, and 4 workshop papers were carefully reviewed and selected from 214 submissions. The conference provides opportunities for the cross-fertilization of approaches, techniques and ideas from the many fields that comprise AIED, including computer science, cognitive and learning sciences, education, game design, psychology, sociology, linguistics as well as many domain-specific areas. ​•The conference was held virtually due to the COVID-19 pandemic.

This book gathers selected papers presented at the conference “Advances in 3D Image and Graphics Representation, Analysis, Computing and Information Technology,” one of the first initiatives devoted to the problems of 3D imaging in all contemporary scientific and application areas. The aim of the conference was to establish a platform for experts to combine their efforts and share their ideas in the related areas in order to promote and accelerate future development. This second volume discusses algorithms and applications, focusing mainly on the following topics: 3D printing technologies; naked, dynamic and auxiliary 3D displays; VR/AR/MR devices; VR camera technologies; microprocessors for 3D data processing; advanced 3D computing systems; 3D data-storage technologies; 3D data networks and technologies; 3D data intelligent processing; 3D data cryptography and security; 3D visual quality estimation and measurement; and 3D decision support and information systems.

This book collects contributions to the XXIII international conference “Nonlinear dynamics of electronic systems”. Topics range from non-linearity in electronic circuits to synchronisation effects in complex networks to biological systems, neural dynamics and the complex organisation of the brain. Resting on a solid mathematical basis, these investigations address highly interdisciplinary problems in physics, engineering, biology and biochemistry.

Learning and Memory: A Comprehensive Reference, Second Edition, Four Volume Set is the authoritative resource for scientists and students interested in all facets of learning and memory. This updated edition includes chapters that reflect the state-of-the-art of research in this area. Coverage of sleep and memory has been significantly expanded, while neuromodulators in memory processing, neurogenesis and epigenetics are also covered in greater detail. New chapters have been included to reflect the massive increase in research into working memory and the educational relevance of memory research. No other reference work covers so wide a territory and in so much depth. - Provides the most comprehensive and authoritative resource available on the study of learning and memory and its mechanisms - Incorporates the expertise of over 150 outstanding investigators in the field, providing a'one-stop'resource of reputable information from world-leading scholars with easy cross-referencing of related articles to promote understanding and further research - Includes further reading for each chapter that helps readers continue their research - Includes a glossary of key terms that is helpful for users who are unfamiliar with neuroscience terminology

The structural optimization procedure presented in this book makes it possible to achieve seismic protection through integrated structural/control system design. In particular, it is explained how slender structural systems with a high seismic performance can be achieved through inclusion of viscous and viscoelastic dampers as an integral part of the system. Readers are provided with essential introductory information on passive structural control and passive energy dissipation systems. Dynamic analyses of both single and multiple degree of freedom systems are performed in order to verify the achievement of pre-assigned performance targets, and it is explained how the optimal integrated design methodology, also relevant to retrofitting of existing buildings, should be applied. The book illustrates how structural control research is opening up new possibilities in structural forms and configurations without compromising structural performance.

Since Lord Rayleigh introduced the idea of viscous damping in his classic work'The Theory of Sound'in 1877, it has become standard practice to use this approach in dynamics, covering a wide range of applications from aerospace to civil engineering. However, in the majority of practical cases this approach is adopted more for mathematical convenience than for modeling the physics of vibration damping. Over the past decade, extensive research has been undertaken on more general “non-viscous” damping models and vibration of non-viscously damped systems. This book, along with a related book Structural Dynamic Analysis with Generalized Damping Models: Analysis, is the first comprehensive study to cover vibration problems with general non-viscous damping. The author draws on his considerable research experience to produce a text covering: parametric senistivity of damped systems; identification of viscous damping; identification of non-viscous damping; and some tools for the quanitification of damping. The book is written from a vibration theory standpoint, with numerous worked examples which are relevant across a wide range of mechanical, aerospace and structural engineering applications. Contents 1. Parametric Sensitivity of Damped Systems. 2. Identification of Viscous Damping. 3. Identification of Non-viscous Damping. 4. Quantification of Damping. About the Authors Sondipon Adhikari is Chair Professor of Aerospace Engineering at Swansea University, Wales. His wide-ranging and multi-disciplinary research interests include uncertainty quantification in computational mechanics, bio- and nanomechanics, dynamics of complex systems, inverse problems for linear and nonlinear dynamics, and renewable energy. He is a technical reviewer of 97 international journals, 18 conferences and 13 funding bodies.He has written over 180 refereed journal papers, 120 refereed conference papers and has authored or co-authored 15 book chapters.

Selected, peer reviewed papers from the 2014 3rd International Conference on Manufacture Engineering, Quality and Production System (ICMEQP 2014), February 27-28, 2014, Hong Kong, China

Selected, peer reviewed papers from the 2nd International Conference on Civil Engineering, Architecture and Building Materials (CEABM 2012), May 25-27, 2012, Yantai, China

The two-volume set LNCS 7552 + 7553 constitutes the proceedings of the 22nd International Conference on Artificial Neural Networks, ICANN 2012, held in Lausanne, Switzerland, in September 2012. The 162 papers included in the proceedings were carefully reviewed and selected from 247 submissions. They are organized in topical sections named: theoretical neural computation; information and optimization; from neurons to neuromorphism; spiking dynamics; from single neurons to networks; complex firing patterns; movement and motion; from sensation to perception; object and face recognition; reinforcement learning; bayesian and echo state networks; recurrent neural networks and reservoir computing; coding architectures; interacting with the brain; swarm intelligence and decision-making; mulitlayer perceptrons and kernel networks; training and learning; inference and recognition; support vector machines; self-organizing maps and clustering; clustering, mining and exploratory analysis; bioinformatics; and time weries and forecasting.

This selection of reviews gives an up-to-date picture of memory research. Great progress has been made in identifying the memory trace at the molecular and cellular level and individual reviews address the major mechanisms by which changes in synaptic strength can persist. Exciting research at the systems level is also reviewed including the growing importance of changes in inhibitory interneurons and how they play a role in memory formation. Finally, reviews present cognitive and neurobiological models of human memory that explain, characterize and organize the act of memory within a coherent framework. - Provides an unique overview that covers all perspectives and methodological approaches to memory - Broad coverage of memory research from molecular to human studies in one source - Up-to-date reviews give the latest important ideas on memory formation

Terrestrial fluids, earthquakes and volcanoes: The Hiroshi Wakita volume III is a special publication to honor Professor Hiroshi Wakita for his scientific contribution to science, which has been closely linked with one of the major objectives of this 2008 International Year for the Earth Planet. Reducing natural risks in active tectonic and volcanic environments by searching and detecting early warning hydrological and geochemical signatures related to earthquakes and volcanic eruptions has been a major life research goal for Hiroshi Wakita. This third special issue of Pure and Applied Geophysics consists of 9 original papers written by researchers from Taiwan, Italy, Turkey, Iceland, USA, Sweden, India and Spain dealing with various aspects of the role of terrestrial fluids in earthquake and volcanic processes. It also includes a list of Hiroshi Wakita's scientific publications. This volume III will be useful to students and professional researchers who are interested in the role of terrestrial fluids in earthquakes and volcanic activity.

Monoaminergic Modulation of Cortical Excitability serves as an integrative and comprehensive comparison of the diverse and complex modulatory action of dopamine, noradrenaline, and serotonin receptors in the cortex. The volume is organized into several sections offering a broad spectrum of opinions on how the monoamine systems affect cortical function from a cellular/sub-cellular level to a system level. The complexity of these interactions are discussed in light of recent data showing how disruption of these systems dramatically affects the memory formation and information processing in the cortex.

This book is a result of many years of author's research and teaching on random vibration and control. It was used as lecture notes for a graduate course. It provides a systematic review of theory of probability, stochastic processes, and stochastic calculus. The feedback control is also reviewed in the book. Random vibration analyses of SDOF, MDOF and continuous structural systems are presented in a pedagogical order. The application of the random vibration theory to reliability and fatigue analysis is also discussed. Recent research results on fatigue analysis of non-Gaussian stress processes are also presented. Classical feedback control, active damping, covariance control, optimal control, sliding control of stochastic systems, feedback control of stochastic time-delayed systems, and probability density tracking control are studied. Many control results are new in the literature and included in this book for the first time. The book serves as a reference to the engineers who design and maintain structures subject to harsh random excitations including earthquakes, sea waves, wind gusts, and aerodynamic forces, and would like to reduce the damages of structural systems due to random excitations.· Comprehensive review of probability theory, and stochastic processes· Random vibrations· Structural reliability and fatigue, Non-Gaussian fatigue· Monte Carlo methods· Stochastic calculus and engineering applications· Stochastic feedback controls and optimal controls· Stochastic sliding mode controls· Feedback control of stochastic time-delayed systems· Probability density tracking control