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The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world.

Specialist Periodical Reports provide systematic and detailed review coverage of progress in the major areas of chemical research. Written by experts in their specialist fields the series creates a unique service for the active research chemist, supplying regular critical in-depth accounts of progress in particular areas of chemistry. For over 80 years the Royal Society of Chemistry and its predecessor, the Chemical Society, have been publishing reports charting developments in chemistry, which originally took the form of Annual Reports. However, by 1967 the whole spectrum of chemistry could no longer be contained within one volume and the series Specialist Periodical Reports was born. The Annual Reports themselves still existed but were divided into two, and subsequently three, volumes covering Inorganic, Organic and Physical Chemistry. For more general coverage of the highlights in chemistry they remain a'must'. Since that time the SPR series has altered according to the fluctuating degree of activity in various fields of chemistry. Some titles have remained unchanged, while others have altered their emphasis along with their titles; some have been combined under a new name whereas others have had to be discontinued. The current list of Specialist Periodical Reports can be seen on the inside flap of this volume.

Specialist Periodical Reports provide systematic and detailed review coverage of progress in the major areas of chemical research. Written by experts in their specialist fields the series creates a unique service for the active research chemist, supplying regular critical in-depth accounts of progress in particular areas of chemistry. For over 80 years the Royal Society of Chemistry and its predecessor, the Chemical Society, have been publishing reports charting developments in chemistry, which originally took the form of Annual Reports. However, by 1967 the whole spectrum of chemistry could no longer be contained within one volume and the series Specialist Periodical Reports was born. The Annual Reports themselves still existed but were divided into two, and subsequently three, volumes covering Inorganic, Organic and Physical Chemistry. For more general coverage of the highlights in chemistry they remain a'must'. Since that time the SPR series has altered according to the fluctuating degree of activity in various fields of chemistry. Some titles have remained unchanged, while others have altered their emphasis along with their titles; some have been combined under a new name whereas others have had to be discontinued. The current list of Specialist Periodical Reports can be seen on the inside flap of this volume.

Biochemistry of the Amino Acids, Second Edition, Volume II focuses on the trends in research on amino acids and biochemistry. Given considerations are incorporation of amino acids into proteins, amino acid sequences, and discovery of amino acids. The first part of the book deals with intermediary metabolism of amino acids. Particularly noted are alanine, aspartic, adenylosuccinic, hydroxyaspartic acids, and asparagine. The book also has discussions on glutamic acid, glutamine, glycine, serine, and sarcosine. The processes and syntheses involved in these acids are noted. Another part of the book focuses on the formation, degradation, reactions, and conversion of acids. The processes and experiments discussed are supported by numerical analysis, and the biosynthesis of acids in microorganisms is also considered. The book also notes some disorders of amino acid metabolism in humans. These disorders include cystinuria, glycinuria, ammonemia, prolinemia, maple syrup urine disease, and homocystinuria. Discussions focus on how these diseases develop and the symptoms associated with them. The book is a vital source of data for readers interested in the study of amino acids.

Protein and Amino Acid Requirements of Mammals focuses on the determination of the protein and amino acid requirements of various mammals, including man in particular. The selection first offers information on some species and age differences in amino acid requirements and the methods of measuring the nutritive value of protein hydrolysates and amino acid mixtures. Discussions focus on assay methods based on protein regeneration; specificity of amino acid requirements; amino acid requirements for nitrogen equilibrium in the adult; and composition of tissue proteins and amino acid requirements for growth. The text then examines the laboratory evaluation of amino acid mixtures and protein hydrolysates and dietary proteins and synthesis of tissue proteins. Topics include role of dietary proteins in the hypertrophy of gonads, effect of dietary proteins on repletion of liver proteins, and effect of dietary proteins on the synthesis of plasma proteins. The publication examines the protein and amino acid requirements of man, including qualitative amino acid requirements of various species, growth and protein and amino acid needs, and metabolic interactions of essential and nonessential amino acids. The selection is a dependable reference for researchers interested in the determination of the protein and amino acid requirements of mammals, including man.

Amino Acids, Proteins, and Cancer Biochemistry focuses on the contributions of Jesse P. Greenstein to biological chemistry, including kinetics, protein mixtures, metabolism, tumors, and biosynthesis. The selection first offers information on quantitative nutritional and in vivo metabolic studies with water-soluble, chemically defined diets and internal hydrogen bonding in ribonuclease. Discussions focus on the effects of deuterium on transition temperature, kinetics of deuterium-hydrogen exchange, applications of chemically denned diets, formulation of water-soluble, chemically defined diets, and large-scale preparation of optically pure amino acids. The manuscript then examines the chromatographic evaluation of protein mixtures and observations on the activation of amino acids and biosynthesis of peptide bonds, including synthesis of phenylacetylglutamine and benzoylglycine, studies on amino acyl adenylates, and synthesis of glutamine. The publication ponders on free amino acids and related substances in normal and neoplastic tissues; nucleic acids of normal tissues and tumors; and carbohydrate metabolism in ascites tumor and HeLa cells. Topics include carbohydrate metabolism of ascites tumor cells, comparative biochemistry of glycolysis, DNA and the genetic concept of cancer, and constancy of free amino acid patterns of tissues. The selection is a valuable source of data for biochemists and researchers interested in amino acids, proteins, and cancer biochemistry.

Protein and Amino Acid Nutrition describes the state of knowledge concerning the nutrition of proteins and amino acids. Topics range from the effect of some therapeutic agents on protein and amino acid nutrition, to species and age differences in amino acid requirements; utilization of D-amino acids; effect of proteins and amino acids on the growth of adult tissue in vitro; and amino acid requirements of animals and young adults. This volume is organized into 16 chapters and begins with an overview of the nutritional implications of the metabolic interrelationships of amino acids. The next chapters discuss experiments that tested the differences in amino acid requirements due to the differences in age and in species among animals, the biochemical individuality of amino acid requirements, and the utilization of dietary proteins. This book explains the synthesis of tissue proteins in relation to the essential amino acids; the link between food energy and nitrogen metabolism; and the use of the repletion method to measure the nutritive value of proteins, protein hydrolyzates, and amino acid mixtures. The final chapter discusses the nutritional needs of the older age groups. This book is intended for scientists, students, and researchers interested in human and animal nutrition.