24 results on '"Yen-Yu Chen"'
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2. Structural and Mechanistic Basis for Gbetagamma-mediated Activation of Phosphoinositide 3-kinase-gamma
3. A Ciliary SMOOTHENED-GRK2-PKA Signaling Pathway Initiates Hedgehog Signal Transduction
4. Molecular basis for Gβγ-mediated activation of phosphoinositide 3-kinase γ
5. Isoform Specific Regulation of Adenylyl Cyclase 5 by Gβγ
6. Structures of atypical chemokine receptor 3 reveal the basis for its promiscuity and signaling bias
7. Seven structures of atypical chemokine receptor 3 reveal the molecular bases for its promiscuity and signaling bias
8. Exploring the structural determinants for inhibitor selectivity towards the BACE protein family using structure-based molecular design
9. Cryo‐EM Structure of Atypical Chemokine Receptor 3 (ACKR3) in Complex with its Endogenous Ligand CXCL12
10. The Open Question of How GPCRs Interact with GPCR Kinases (GRKs)
11. A Structure-Based Discovery Platform for BACE2 and the Development of Selective BACE Inhibitors
12. OPTIMIZING THE TLD-100H READOUT SYSTEM UNDER VARIOUS RADIOACTIVE I-131 DOSES VIA THE REVISED TAGUCHI DYNAMIC QUALITY LOSS FUNCTION
13. A New Paroxetine-Based GRK2 Inhibitor Reduces Internalization of the μ-Opioid Receptor
14. BIOKINETIC MODEL OF Tc-99m MIBI FOR EIGHT PATIENTS UNDERGONE MYOCARDIAL PERFUSION EXAMINATION via GAMMA CAMERA AND MATLAB PROGRAM: AN IN-VIVO STUDY
15. Development of an Efficient Enzyme Production and Structure-Based Discovery Platform for BACE1 Inhibitors
16. Cover Feature: Highly Selective and Potent Human β-Secretase 2 (BACE2) Inhibitors against Type 2 Diabetes: Design, Synthesis, X-ray Structure and Structure-Activity Relationship Studies (ChemMedChem 5/2019)
17. Highly Selective and Potent Human β‐Secretase 2 (BACE2) Inhibitors against Type 2 Diabetes: Design, Synthesis, X‐ray Structure and Structure–Activity Relationship Studies
18. Design, synthesis, X-ray studies, and biological evaluation of novel BACE1 inhibitors with bicyclic isoxazoline carboxamides as the P3 ligand
19. Design, synthesis, and X-ray structural studies of BACE-1 inhibitors containing substituted 2-oxopiperazines as P1′-P2′ ligands
20. Development of an efficient structure‐based drug discovery platform for BACE1 Inhibitors for the treatment of Alzheimer's Disease
21. Design of potent and highly selective inhibitors for human β-secretase 2 (memapsin 1), a target for type 2 diabetes
22. Structure-based design, synthesis and biological evaluation of novel β-secretase inhibitors containing a pyrazole or thiazole moiety as the P3 ligand
23. Evaluation of Electrospinning Keratin Membrane with Gelatin Addition in Relation to Nerve Regeneration
24. Screening a cDNA Library for Protein–Protein Interactions Directly in Planta
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