70 results on '"Wood, David K."'
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2. CDK4/6 inhibition enhances SHP2 inhibitor efficacy and is dependent upon RB function in malignant peripheral nerve sheath tumors
3. Genetic reversal of the globin switch concurrently modulates both fetal and sickle hemoglobin and reduces red cell sickling
4. iCLOTS: open-source, artificial intelligence-enabled software for analyses of blood cells in microfluidic and microscopy-based assays
5. Ex vivo to in vivo model of malignant peripheral nerve sheath tumors for precision oncology
6. Robust microtubule dynamics facilitate low-tension kinetochore detachment in metaphase
7. JAK-STAT inhibition reduces endothelial prothrombotic activation and leukocyte–endothelial proadhesive interactions
8. CDK4/6 inhibition enhances SHP2 inhibitor efficacy and is dependent upon restoration of RB function in malignant peripheral nerve sheath tumors
9. Fluorescence Lifetime Measurement of Prefibrillar Sickle Hemoglobin Oligomers as a Platform for Drug Discovery in Sickle Cell Disease
10. Ex vivo to in vivo model of malignant peripheral nerve sheath tumors for precision oncology
11. Microsystems Models of Pathophysiology
12. Microfluidic Methods to Advance Mechanistic Understanding and Translational Research in Sickle Cell Disease
13. Stromal architecture directs early dissemination in pancreatic ductal adenocarcinoma
14. Extracellular Vesicles Mediate the Intercellular Exchange of Nanoparticles
15. The effect of rigid cells on blood viscosity: linking rheology and sickle cell anemia
16. Feature tracking microfluidic analysis reveals differential roles of viscosity and friction in sickle cell blood
17. Simultaneous quantification of blood rheology and oxygen saturation to evaluate affinity-modifying therapies in sickle cell disease
18. A scalable 3D tissue culture pipeline to enable functional therapeutic screening for pulmonary fibrosis
19. Model-Predicted Clinical Factors Impacting Patient-Specific Response of Sickle Cells to Voxelotor in a Microfluidic Platform
20. Effects of BCL11A Shmir-Induced Post-Transcriptional Silencing on Hemoglobin Polymer Inhibition in Single Red Blood Cells at Physiologic Oxygen Tension
21. Visualizing Sickle Cell Disease Whole Blood Flow and Viscosity through Modifications to Hemoglobin Levels from a Simple Blood Transfusion
22. Ionophore-mediated swelling of erythrocytes as a therapeutic mechanism in sickle cell disease
23. An irradiated marrow niche reveals a small non-collagenous protein mediator of homing, dermatopontin
24. GPCR‐mediated YAP/TAZ inactivation in fibroblasts via EPAC1/2, RAP2C, and MAP4K7
25. MetAP2 inhibition modifies hemoglobin S to delay polymerization and improves blood flow in sickle cell disease
26. Extracellular vesicles mediate the intercellular exchange of nanoparticles
27. Stromal architecture directs early dissemination in pancreatic ductal adenocarcinoma
28. CometChip
29. An Experimental-Computational Approach to Quantify Blood Rheology in Sickle Cell Disease
30. Robust Pre-Clinical Results and Large-Scale Manufacturing Process for Edit-301: An Autologous Cell Therapy for the Potential Treatment of SCD
31. Ruxolitinib Reduces Endothelial Pro-Adhesive Interactions: Implications for JAK2V617+ MPN Thrombosis
32. Voxelotor Improves Sickle Red Blood Cell Flow Under Hypoxia in a Microfluidic Venule
33. Microscale Collagen and Fibroblast Interactions Enhance Primary Human Hepatocyte Functions in Three-Dimensional Models
34. 5‐(Hydroxymethyl)furfural restores low‐oxygen rheology of sickle trait bloodin vitro
35. A microfluidic platform for simultaneous quantification of oxygen-dependent viscosity and shear thinning in sickle cell blood
36. Microscale Collagen and Fibroblast Interactions Enhance Primary Human Hepatocyte Functions in 3-Dimensional Models
37. High-throughput assessment of hemoglobin polymer in single red blood cells from sickle cell patients under controlled oxygen tension
38. Validation of BCL11A As Therapeutic Target in Sickle Cell Disease: Results from the Adult Cohort of a Pilot/Feasibility Gene Therapy Trial Inducing Sustained Expression of Fetal Hemoglobin Using Post-Transcriptional Gene Silencing
39. MetAP2 Inhibition Modifies Hemoglobin S (HbS) to Delay Polymerization and Improve Blood Flow in Sickle Cell Disease
40. SEMA4C is a novel target to limit osteosarcoma growth, progression, and metastasis
41. Rapid and inefficient kinetics of sickle hemoglobin fiber growth
42. SEMA4C is a novel target to limit osteosarcoma growth, progression, and metastasis
43. A High-Throughput Workflow to Study Remodeling of Extracellular Matrix-Based Microtissues
44. Oxygen-dependent flow of sickle trait blood as anin vitrotherapeutic benchmark for sickle cell disease treatments
45. RobotEye Technology for Thermal Target Tracking Using Predictive Control
46. Distant Relations: Macrophage Functions in the Metastatic Niche
47. A high-throughput microtissue platform to probe endothelial function in vitro
48. In vitro elucidation of the role of pericellular matrix in metastatic extravasation and invasion of breast carcinoma cells
49. Extracellular fluid tonicity impacts sickle red blood cell deformability and adhesion
50. Low-latency Vision-based Fiducial Detection and Localization for Object Tracking
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