62 results on '"Toyoda, Yu"'
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2. Biochemical characterization of Jr(a−) blood type‐related ABCG2 variants: Arg147Trp and Ser572Arg disrupt the plasma membrane localization of ABCG2
3. Membrane Transporter (s)–mediated Regulation of Urate and Vitamin C Behavior in the Body
4. Dysuricemia
5. SVCT2/SLC23A2 is a sodium-dependent urate transporter: functional properties and practical application
6. Vitamin C transporter SVCT1 serves a physiological role as a urate importer: functional analyses and in vivo investigations
7. Urate Transporter ABCG2 Function and Asymptomatic Hyperuricemia: A Retrospective Cohort Study of CKD Progression
8. Identification of a dysfunctional exon-skipping splice variant in GLUT9/SLC2A9 causal for renal hypouricemia type 2
9. Recent Advances in Research on Vitamin C Transporters
10. Hepatic Niemann-Pick C1-Like 1 exacerbates non-alcoholic fatty liver disease by re-absorbing specific biliary oxysterols
11. Genome-wide meta-analysis between renal overload type and renal underexcretion type of clinically defined gout in Japanese populations
12. OAT10/SLC22A13 Acts as a Renal Urate Re-Absorber: Clinico-Genetic and Functional Analyses With Pharmacological Impacts
13. Human ABC Transporter ABCC11: Looking Back Pioneers’ Odyssey and Creating a New Path Toward Clinical Application
14. Identification of Inhibitory Activities of Dietary Flavonoids against URAT1, a Renal Urate Re-Absorber: In Vitro Screening and Fractional Approach Focused on Rooibos Leaves
15. Identification of an exporter that regulates vitamin C supply from blood to the brain
16. Increase of serum uric acid levels associated with APOE ε2 haplotype: a clinico-genetic investigation and in vivo approach
17. Drugs Affecting Epigenetic Modifications of ABC Transporters for Drug Resistance
18. A Proposal for Practical Diagnosis of Renal Hypouricemia: Evidenced from Genetic Studies of Nonfunctional Variants of URAT1/SLC22A12 among 30,685 Japanese Individuals
19. Genetic epidemiological analysis of hypouricaemia from 4993 Japanese on non-functional variants of URAT1/SLC22A12 gene
20. Porphyrin accumulation in humans with common dysfunctional variants of ABCG2, a porphyrin transporter: potential association with acquired photosensitivity
21. Substantial anti-gout effect conferred by common and rare dysfunctional variants of URAT1/SLC22A12
22. Association Between Earwax-Determinant Genotypes and Acquired Middle Ear Cholesteatoma in a Japanese Population
23. MRP8 (ABCC11)
24. Identification of Two Dysfunctional Variants in the ABCG2 Urate Transporter Associated with Pediatric-Onset of Familial Hyperuricemia and Early-Onset Gout
25. Pathophysiological impact of dysfunctional common and rare variants of urate transporter ABCG2 on urate-related diseases
26. Production of Cells with Targeted Integration of Gene Variants of Human ABC Transporter for Stable and Regulated Expression Using the Flp Recombinase System
27. Identification of a dysfunctional splicing mutation in the SLC22A12/URAT1 gene causing renal hypouricaemia type 1: a report on two families
28. Soy Isoflavone Genistein Inhibits an Axillary Osmidrosis Risk Factor ABCC11: In Vitro Screening and Fractional Approach for ABCC11-Inhibitory Activities in Plant Extracts and Dietary Flavonoids
29. Febuxostat inhibited axillary osmidrosis risk factor ATP‐binding cassette transporter C11 in vitro
30. Identification of GLUT12/SLC2A12 as a urate transporter that regulates the blood urate level in hyperuricemia model mice
31. Omega-3 Polyunsaturated Fatty Acids Inhibit the Function of Human URAT1, a Renal Urate Re-Absorber
32. Subtype-specific gout susceptibility loci and enrichment of selection pressure on ABCG2 and ALDH2 identified by subtype genome-wide meta-analyses of clinically defined gout patients
33. Inhibitory effect of Citrus flavonoids on the in vitro transport activity of human urate transporter 1 (URAT1/SLC22A12), a renal re-absorber of urate
34. Pathophysiological importance of bile cholesterol reabsorption: hepatic NPC1L1-exacerbated steatosis and decreasing VLDL-TG secretion in mice fed a high-fat diet
35. Dysfunctional missense variant of OAT10/SLC22A13 decreases gout risk and serum uric acid levels
36. Familial early-onset hyperuricemia and gout associated with a newly identified dysfunctional variant in urate transporter ABCG2
37. Inhibitors of Human ABCG2: From Technical Background to Recent Updates With Clinical Implications
38. Identification of hepatic NPC1L1 as an NAFLD risk factor evidenced by ezetimibe‐mediated steatosis prevention and recovery
39. Are human ATP-binding cassette transporter C11 and earwax associated with the incidence of cholesteatoma?
40. Investigation of the transport of xanthine dehydrogenase inhibitors by the urate transporter ABCG2
41. Multiple common and rare variants of ABCG2 cause gout
42. Clinical and Molecular Evidence of ABCC11 Protein Expression in Axillary Apocrine Glands of Patients with Axillary Osmidrosis
43. Metabolomics of an in vitro liver model containing primary hepatocytes assembling around an endothelial cell network: comparative study on the metabolic stability and the effect of acetaminophen treatment
44. Spontaneous Production of Glutathione-Conjugated Forms of 1,2-Dichloropropane: Comparative Study on Metabolic Activation Processes of Dihaloalkanes Associated with Occupational Cholangiocarcinoma
45. Identification of Febuxostat as a New Strong ABCG2 Inhibitor: Potential Applications and Risks in Clinical Situations
46. GWAS of clinically defined gout and subtypes identifies multiple susceptibility loci that include urate transporter genes
47. Regulation of the Axillary Osmidrosis-Associated ABCC11 Protein Stability by N-Linked Glycosylation: Effect of Glucose Condition
48. Halogenated hydrocarbon solvent-related cholangiocarcinoma risk: biliary excretion of glutathione conjugates of 1,2-dichloropropane evidenced by untargeted metabolomics analysis
49. GOUT AND NUCLEIC ACID METABOLISM
50. Diagnosis of Human Axillary Osmidrosis by Genotyping of the HumanABCC11Gene: Clinical Practice and Basic Scientific Evidence
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