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1. Altered enhancer-promoter interaction leads toMNX1expression in pediatric acute myeloid leukemia with t(7;12)(q36;p13)

Author

Weichenhan, Dieter, primary, Riedel, Anna, additional, Sollier, Etienne, additional, Toprak, Umut H., additional, Hey, Joschka, additional, Breuer, Kersten, additional, Wierzbinska, Justyna A., additional, Touzart, Aurore, additional, Lutsik, Pavlo, additional, Baehr, Marion, additional, Oestlund, Anders, additional, Nilsson, Christina, additional, Jacobsson, Susanna, additional, Edler, Marcel, additional, Waraky, Ahmed, additional, Behrens, Yvonne Lisa, additional, Goehring, Gudrun, additional, Schlegelberger, Brigitte, additional, Steinek, Clemens, additional, Harz, Hartmann, additional, Leonhardt, Heinrich, additional, Dolnik, Anna, additional, Reinhardt, Dirk, additional, Bullinger, Lars, additional, Palmqvist, Lars, additional, Lipka, Daniel B., additional, and Plass, Christoph, additional

Published
2023
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2. S120: MNX1-ACTIVATING ENHANCER HIJACKING EVENTS IN ACUTE MYELOID LEUKEMIA WITH DELETIONS ON CHROMOSOME 7Q

Author

Riedel, Anna, primary, Wierzbińska, Justyna A., additional, Toprak, Umut H., additional, Touzart, Aurore, additional, Sollier, Etienne, additional, Kelekçi, Simge, additional, Kelly, Katherine, additional, Weichenhan, Dieter, additional, Pejkovska, Anastasija, additional, Goyal, Ashish, additional, Meinen, Charlotte, additional, Schlesner, Matthias, additional, Westermann, Frank, additional, Brors, Benedikt, additional, Bullinger, Lars, additional, Greif, Philipp, additional, Lübbert, Michael, additional, Heidel, Florian, additional, Fischer, Thomas, additional, Gebhard, Claudia, additional, Schlegelberger, Brigitte, additional, Göhring, Gudrun, additional, Behrens, Yvonne, additional, Jahn, Ekaterina, additional, Döhner, Hartmut, additional, Döhner, Konstanze, additional, Delwel, Ruud, additional, Lutsik, Pavlo, additional, Lipka, Daniel B., additional, and Plass, Christoph, additional

Published
2023
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3. Supplementary Patient Data from NRG1 Fusions in KRAS Wild-Type Pancreatic Cancer

Author

Heining, Christoph, primary, Horak, Peter, primary, Uhrig, Sebastian, primary, Codo, Paula L., primary, Klink, Barbara, primary, Hutter, Barbara, primary, Fröhlich, Martina, primary, Bonekamp, David, primary, Richter, Daniela, primary, Steiger, Katja, primary, Penzel, Roland, primary, Endris, Volker, primary, Ehrenberg, Karl Roland, primary, Frank, Stephanie, primary, Kleinheinz, Kortine, primary, Toprak, Umut H., primary, Schlesner, Matthias, primary, Mandal, Ranadip, primary, Schulz, Lothar, primary, Lambertz, Helmut, primary, Fetscher, Sebastian, primary, Bitzer, Michael, primary, Malek, Nisar P., primary, Horger, Marius, primary, Giese, Nathalia A., primary, Strobel, Oliver, primary, Hackert, Thilo, primary, Springfeld, Christoph, primary, Feuerbach, Lars, primary, Bergmann, Frank, primary, Schröck, Evelin, primary, von Kalle, Christof, primary, Weichert, Wilko, primary, Scholl, Claudia, primary, Ball, Claudia R., primary, Stenzinger, Albrecht, primary, Brors, Benedikt, primary, Fröhling, Stefan, primary, and Glimm, Hanno, primary

Published
2023
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4. Supplementary Table S1 from NRG1 Fusions in KRAS Wild-Type Pancreatic Cancer

Author

Heining, Christoph, primary, Horak, Peter, primary, Uhrig, Sebastian, primary, Codo, Paula L., primary, Klink, Barbara, primary, Hutter, Barbara, primary, Fröhlich, Martina, primary, Bonekamp, David, primary, Richter, Daniela, primary, Steiger, Katja, primary, Penzel, Roland, primary, Endris, Volker, primary, Ehrenberg, Karl Roland, primary, Frank, Stephanie, primary, Kleinheinz, Kortine, primary, Toprak, Umut H., primary, Schlesner, Matthias, primary, Mandal, Ranadip, primary, Schulz, Lothar, primary, Lambertz, Helmut, primary, Fetscher, Sebastian, primary, Bitzer, Michael, primary, Malek, Nisar P., primary, Horger, Marius, primary, Giese, Nathalia A., primary, Strobel, Oliver, primary, Hackert, Thilo, primary, Springfeld, Christoph, primary, Feuerbach, Lars, primary, Bergmann, Frank, primary, Schröck, Evelin, primary, von Kalle, Christof, primary, Weichert, Wilko, primary, Scholl, Claudia, primary, Ball, Claudia R., primary, Stenzinger, Albrecht, primary, Brors, Benedikt, primary, Fröhling, Stefan, primary, and Glimm, Hanno, primary

Published
2023
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5. Data from NRG1 Fusions in KRAS Wild-Type Pancreatic Cancer

Author

Heining, Christoph, primary, Horak, Peter, primary, Uhrig, Sebastian, primary, Codo, Paula L., primary, Klink, Barbara, primary, Hutter, Barbara, primary, Fröhlich, Martina, primary, Bonekamp, David, primary, Richter, Daniela, primary, Steiger, Katja, primary, Penzel, Roland, primary, Endris, Volker, primary, Ehrenberg, Karl Roland, primary, Frank, Stephanie, primary, Kleinheinz, Kortine, primary, Toprak, Umut H., primary, Schlesner, Matthias, primary, Mandal, Ranadip, primary, Schulz, Lothar, primary, Lambertz, Helmut, primary, Fetscher, Sebastian, primary, Bitzer, Michael, primary, Malek, Nisar P., primary, Horger, Marius, primary, Giese, Nathalia A., primary, Strobel, Oliver, primary, Hackert, Thilo, primary, Springfeld, Christoph, primary, Feuerbach, Lars, primary, Bergmann, Frank, primary, Schröck, Evelin, primary, von Kalle, Christof, primary, Weichert, Wilko, primary, Scholl, Claudia, primary, Ball, Claudia R., primary, Stenzinger, Albrecht, primary, Brors, Benedikt, primary, Fröhling, Stefan, primary, and Glimm, Hanno, primary

Published
2023
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6. Supplementary Figure S2 from NRG1 Fusions in KRAS Wild-Type Pancreatic Cancer

Author

Heining, Christoph, primary, Horak, Peter, primary, Uhrig, Sebastian, primary, Codo, Paula L., primary, Klink, Barbara, primary, Hutter, Barbara, primary, Fröhlich, Martina, primary, Bonekamp, David, primary, Richter, Daniela, primary, Steiger, Katja, primary, Penzel, Roland, primary, Endris, Volker, primary, Ehrenberg, Karl Roland, primary, Frank, Stephanie, primary, Kleinheinz, Kortine, primary, Toprak, Umut H., primary, Schlesner, Matthias, primary, Mandal, Ranadip, primary, Schulz, Lothar, primary, Lambertz, Helmut, primary, Fetscher, Sebastian, primary, Bitzer, Michael, primary, Malek, Nisar P., primary, Horger, Marius, primary, Giese, Nathalia A., primary, Strobel, Oliver, primary, Hackert, Thilo, primary, Springfeld, Christoph, primary, Feuerbach, Lars, primary, Bergmann, Frank, primary, Schröck, Evelin, primary, von Kalle, Christof, primary, Weichert, Wilko, primary, Scholl, Claudia, primary, Ball, Claudia R., primary, Stenzinger, Albrecht, primary, Brors, Benedikt, primary, Fröhling, Stefan, primary, and Glimm, Hanno, primary

Published
2023
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7. Supplementary Figure S3 from NRG1 Fusions in KRAS Wild-Type Pancreatic Cancer

Author

Heining, Christoph, primary, Horak, Peter, primary, Uhrig, Sebastian, primary, Codo, Paula L., primary, Klink, Barbara, primary, Hutter, Barbara, primary, Fröhlich, Martina, primary, Bonekamp, David, primary, Richter, Daniela, primary, Steiger, Katja, primary, Penzel, Roland, primary, Endris, Volker, primary, Ehrenberg, Karl Roland, primary, Frank, Stephanie, primary, Kleinheinz, Kortine, primary, Toprak, Umut H., primary, Schlesner, Matthias, primary, Mandal, Ranadip, primary, Schulz, Lothar, primary, Lambertz, Helmut, primary, Fetscher, Sebastian, primary, Bitzer, Michael, primary, Malek, Nisar P., primary, Horger, Marius, primary, Giese, Nathalia A., primary, Strobel, Oliver, primary, Hackert, Thilo, primary, Springfeld, Christoph, primary, Feuerbach, Lars, primary, Bergmann, Frank, primary, Schröck, Evelin, primary, von Kalle, Christof, primary, Weichert, Wilko, primary, Scholl, Claudia, primary, Ball, Claudia R., primary, Stenzinger, Albrecht, primary, Brors, Benedikt, primary, Fröhling, Stefan, primary, and Glimm, Hanno, primary

Published
2023
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8. Supplementary Table S1 from NRG1 Fusions in KRAS Wild-Type Pancreatic Cancer

Author

Heining, Christoph, primary, Horak, Peter, primary, Uhrig, Sebastian, primary, Codo, Paula L., primary, Klink, Barbara, primary, Hutter, Barbara, primary, Fröhlich, Martina, primary, Bonekamp, David, primary, Richter, Daniela, primary, Steiger, Katja, primary, Penzel, Roland, primary, Endris, Volker, primary, Ehrenberg, Karl Roland, primary, Frank, Stephanie, primary, Kleinheinz, Kortine, primary, Toprak, Umut H., primary, Schlesner, Matthias, primary, Mandal, Ranadip, primary, Schulz, Lothar, primary, Lambertz, Helmut, primary, Fetscher, Sebastian, primary, Bitzer, Michael, primary, Malek, Nisar P., primary, Horger, Marius, primary, Giese, Nathalia A., primary, Strobel, Oliver, primary, Hackert, Thilo, primary, Springfeld, Christoph, primary, Feuerbach, Lars, primary, Bergmann, Frank, primary, Schröck, Evelin, primary, von Kalle, Christof, primary, Weichert, Wilko, primary, Scholl, Claudia, primary, Ball, Claudia R., primary, Stenzinger, Albrecht, primary, Brors, Benedikt, primary, Fröhling, Stefan, primary, and Glimm, Hanno, primary

Published
2023
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9. Supplementary Figure S1 from NRG1 Fusions in KRAS Wild-Type Pancreatic Cancer

Author

Heining, Christoph, primary, Horak, Peter, primary, Uhrig, Sebastian, primary, Codo, Paula L., primary, Klink, Barbara, primary, Hutter, Barbara, primary, Fröhlich, Martina, primary, Bonekamp, David, primary, Richter, Daniela, primary, Steiger, Katja, primary, Penzel, Roland, primary, Endris, Volker, primary, Ehrenberg, Karl Roland, primary, Frank, Stephanie, primary, Kleinheinz, Kortine, primary, Toprak, Umut H., primary, Schlesner, Matthias, primary, Mandal, Ranadip, primary, Schulz, Lothar, primary, Lambertz, Helmut, primary, Fetscher, Sebastian, primary, Bitzer, Michael, primary, Malek, Nisar P., primary, Horger, Marius, primary, Giese, Nathalia A., primary, Strobel, Oliver, primary, Hackert, Thilo, primary, Springfeld, Christoph, primary, Feuerbach, Lars, primary, Bergmann, Frank, primary, Schröck, Evelin, primary, von Kalle, Christof, primary, Weichert, Wilko, primary, Scholl, Claudia, primary, Ball, Claudia R., primary, Stenzinger, Albrecht, primary, Brors, Benedikt, primary, Fröhling, Stefan, primary, and Glimm, Hanno, primary

Published
2023
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10. Supplementary Table S2 from NRG1 Fusions in KRAS Wild-Type Pancreatic Cancer

Author

Heining, Christoph, primary, Horak, Peter, primary, Uhrig, Sebastian, primary, Codo, Paula L., primary, Klink, Barbara, primary, Hutter, Barbara, primary, Fröhlich, Martina, primary, Bonekamp, David, primary, Richter, Daniela, primary, Steiger, Katja, primary, Penzel, Roland, primary, Endris, Volker, primary, Ehrenberg, Karl Roland, primary, Frank, Stephanie, primary, Kleinheinz, Kortine, primary, Toprak, Umut H., primary, Schlesner, Matthias, primary, Mandal, Ranadip, primary, Schulz, Lothar, primary, Lambertz, Helmut, primary, Fetscher, Sebastian, primary, Bitzer, Michael, primary, Malek, Nisar P., primary, Horger, Marius, primary, Giese, Nathalia A., primary, Strobel, Oliver, primary, Hackert, Thilo, primary, Springfeld, Christoph, primary, Feuerbach, Lars, primary, Bergmann, Frank, primary, Schröck, Evelin, primary, von Kalle, Christof, primary, Weichert, Wilko, primary, Scholl, Claudia, primary, Ball, Claudia R., primary, Stenzinger, Albrecht, primary, Brors, Benedikt, primary, Fröhling, Stefan, primary, and Glimm, Hanno, primary

Published
2023
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11. Supplementary Figure S2 from NRG1 Fusions in KRAS Wild-Type Pancreatic Cancer

Author

Heining, Christoph, primary, Horak, Peter, primary, Uhrig, Sebastian, primary, Codo, Paula L., primary, Klink, Barbara, primary, Hutter, Barbara, primary, Fröhlich, Martina, primary, Bonekamp, David, primary, Richter, Daniela, primary, Steiger, Katja, primary, Penzel, Roland, primary, Endris, Volker, primary, Ehrenberg, Karl Roland, primary, Frank, Stephanie, primary, Kleinheinz, Kortine, primary, Toprak, Umut H., primary, Schlesner, Matthias, primary, Mandal, Ranadip, primary, Schulz, Lothar, primary, Lambertz, Helmut, primary, Fetscher, Sebastian, primary, Bitzer, Michael, primary, Malek, Nisar P., primary, Horger, Marius, primary, Giese, Nathalia A., primary, Strobel, Oliver, primary, Hackert, Thilo, primary, Springfeld, Christoph, primary, Feuerbach, Lars, primary, Bergmann, Frank, primary, Schröck, Evelin, primary, von Kalle, Christof, primary, Weichert, Wilko, primary, Scholl, Claudia, primary, Ball, Claudia R., primary, Stenzinger, Albrecht, primary, Brors, Benedikt, primary, Fröhling, Stefan, primary, and Glimm, Hanno, primary

Published
2023
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12. Supplementary Table S2 from NRG1 Fusions in KRAS Wild-Type Pancreatic Cancer

Author

Heining, Christoph, primary, Horak, Peter, primary, Uhrig, Sebastian, primary, Codo, Paula L., primary, Klink, Barbara, primary, Hutter, Barbara, primary, Fröhlich, Martina, primary, Bonekamp, David, primary, Richter, Daniela, primary, Steiger, Katja, primary, Penzel, Roland, primary, Endris, Volker, primary, Ehrenberg, Karl Roland, primary, Frank, Stephanie, primary, Kleinheinz, Kortine, primary, Toprak, Umut H., primary, Schlesner, Matthias, primary, Mandal, Ranadip, primary, Schulz, Lothar, primary, Lambertz, Helmut, primary, Fetscher, Sebastian, primary, Bitzer, Michael, primary, Malek, Nisar P., primary, Horger, Marius, primary, Giese, Nathalia A., primary, Strobel, Oliver, primary, Hackert, Thilo, primary, Springfeld, Christoph, primary, Feuerbach, Lars, primary, Bergmann, Frank, primary, Schröck, Evelin, primary, von Kalle, Christof, primary, Weichert, Wilko, primary, Scholl, Claudia, primary, Ball, Claudia R., primary, Stenzinger, Albrecht, primary, Brors, Benedikt, primary, Fröhling, Stefan, primary, and Glimm, Hanno, primary

Published
2023
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13. Supplementary Figure S1 from NRG1 Fusions in KRAS Wild-Type Pancreatic Cancer

Author

Heining, Christoph, primary, Horak, Peter, primary, Uhrig, Sebastian, primary, Codo, Paula L., primary, Klink, Barbara, primary, Hutter, Barbara, primary, Fröhlich, Martina, primary, Bonekamp, David, primary, Richter, Daniela, primary, Steiger, Katja, primary, Penzel, Roland, primary, Endris, Volker, primary, Ehrenberg, Karl Roland, primary, Frank, Stephanie, primary, Kleinheinz, Kortine, primary, Toprak, Umut H., primary, Schlesner, Matthias, primary, Mandal, Ranadip, primary, Schulz, Lothar, primary, Lambertz, Helmut, primary, Fetscher, Sebastian, primary, Bitzer, Michael, primary, Malek, Nisar P., primary, Horger, Marius, primary, Giese, Nathalia A., primary, Strobel, Oliver, primary, Hackert, Thilo, primary, Springfeld, Christoph, primary, Feuerbach, Lars, primary, Bergmann, Frank, primary, Schröck, Evelin, primary, von Kalle, Christof, primary, Weichert, Wilko, primary, Scholl, Claudia, primary, Ball, Claudia R., primary, Stenzinger, Albrecht, primary, Brors, Benedikt, primary, Fröhling, Stefan, primary, and Glimm, Hanno, primary

Published
2023
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14. Data from NRG1 Fusions in KRAS Wild-Type Pancreatic Cancer

Author

Heining, Christoph, primary, Horak, Peter, primary, Uhrig, Sebastian, primary, Codo, Paula L., primary, Klink, Barbara, primary, Hutter, Barbara, primary, Fröhlich, Martina, primary, Bonekamp, David, primary, Richter, Daniela, primary, Steiger, Katja, primary, Penzel, Roland, primary, Endris, Volker, primary, Ehrenberg, Karl Roland, primary, Frank, Stephanie, primary, Kleinheinz, Kortine, primary, Toprak, Umut H., primary, Schlesner, Matthias, primary, Mandal, Ranadip, primary, Schulz, Lothar, primary, Lambertz, Helmut, primary, Fetscher, Sebastian, primary, Bitzer, Michael, primary, Malek, Nisar P., primary, Horger, Marius, primary, Giese, Nathalia A., primary, Strobel, Oliver, primary, Hackert, Thilo, primary, Springfeld, Christoph, primary, Feuerbach, Lars, primary, Bergmann, Frank, primary, Schröck, Evelin, primary, von Kalle, Christof, primary, Weichert, Wilko, primary, Scholl, Claudia, primary, Ball, Claudia R., primary, Stenzinger, Albrecht, primary, Brors, Benedikt, primary, Fröhling, Stefan, primary, and Glimm, Hanno, primary

Published
2023
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15. Supplementary Figure S3 from NRG1 Fusions in KRAS Wild-Type Pancreatic Cancer

Author

Heining, Christoph, primary, Horak, Peter, primary, Uhrig, Sebastian, primary, Codo, Paula L., primary, Klink, Barbara, primary, Hutter, Barbara, primary, Fröhlich, Martina, primary, Bonekamp, David, primary, Richter, Daniela, primary, Steiger, Katja, primary, Penzel, Roland, primary, Endris, Volker, primary, Ehrenberg, Karl Roland, primary, Frank, Stephanie, primary, Kleinheinz, Kortine, primary, Toprak, Umut H., primary, Schlesner, Matthias, primary, Mandal, Ranadip, primary, Schulz, Lothar, primary, Lambertz, Helmut, primary, Fetscher, Sebastian, primary, Bitzer, Michael, primary, Malek, Nisar P., primary, Horger, Marius, primary, Giese, Nathalia A., primary, Strobel, Oliver, primary, Hackert, Thilo, primary, Springfeld, Christoph, primary, Feuerbach, Lars, primary, Bergmann, Frank, primary, Schröck, Evelin, primary, von Kalle, Christof, primary, Weichert, Wilko, primary, Scholl, Claudia, primary, Ball, Claudia R., primary, Stenzinger, Albrecht, primary, Brors, Benedikt, primary, Fröhling, Stefan, primary, and Glimm, Hanno, primary

Published
2023
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16. Supplementary Patient Data from NRG1 Fusions in KRAS Wild-Type Pancreatic Cancer

Author

Heining, Christoph, primary, Horak, Peter, primary, Uhrig, Sebastian, primary, Codo, Paula L., primary, Klink, Barbara, primary, Hutter, Barbara, primary, Fröhlich, Martina, primary, Bonekamp, David, primary, Richter, Daniela, primary, Steiger, Katja, primary, Penzel, Roland, primary, Endris, Volker, primary, Ehrenberg, Karl Roland, primary, Frank, Stephanie, primary, Kleinheinz, Kortine, primary, Toprak, Umut H., primary, Schlesner, Matthias, primary, Mandal, Ranadip, primary, Schulz, Lothar, primary, Lambertz, Helmut, primary, Fetscher, Sebastian, primary, Bitzer, Michael, primary, Malek, Nisar P., primary, Horger, Marius, primary, Giese, Nathalia A., primary, Strobel, Oliver, primary, Hackert, Thilo, primary, Springfeld, Christoph, primary, Feuerbach, Lars, primary, Bergmann, Frank, primary, Schröck, Evelin, primary, von Kalle, Christof, primary, Weichert, Wilko, primary, Scholl, Claudia, primary, Ball, Claudia R., primary, Stenzinger, Albrecht, primary, Brors, Benedikt, primary, Fröhling, Stefan, primary, and Glimm, Hanno, primary

Published
2023
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17. Translocation t(6;7) in AML-M4 cell line GDM-1 results in MNX1 activation through enhancer-hijacking

Author

Weichenhan, Dieter, primary, Riedel, Anna, additional, Meinen, Charlotte, additional, Basic, Alisa, additional, Toth, Reka, additional, Bähr, Marion, additional, Lutsik, Pavlo, additional, Hey, Joschka, additional, Sollier, Etienne, additional, Toprak, Umut H., additional, Kelekçi, Simge, additional, Lin, Yu-Yu, additional, Hakobyan, Mariam, additional, Touzart, Aurore, additional, Goyal, Ashish, additional, Wierzbinska, Justyna A., additional, Schlesner, Matthias, additional, Westermann, Frank, additional, Lipka, Daniel B., additional, and Plass, Christoph, additional

Published
2023
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18. Exploration of whole genome and transcriptome sequencing data lacks evidence for oncogenic viral elements to drive the pathogenesis of T-cell prolymphocytic leukemia

Author

Patil, Paurnima, primary, Toprak, Umut H., additional, Seufert, Julian, additional, Braun, Till, additional, Bernhart, Stephan H., additional, Wiehle, Laura, additional, Müller, Annika, additional, Schlesner, Matthias, additional, Herling, Marco, additional, Lichter, Peter, additional, Stilgenbauer, Stephan, additional, Siebert, Reiner, additional, and Zapatka, Marc, additional

Published
2022
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19. Focal structural variants revealed by whole genome sequencing disrupt the histone demethylase KDM4C in B-cell lymphomas

Author

Lopez, Cristina, primary, Schleussner, Nikolai, additional, Bernhart, Stephan H., additional, Kleinheinz, Kortine, additional, Sungalee, Stephanie, additional, Sczakiel, Henrike L., additional, Kretzmer, Helene, additional, Toprak, Umut H., additional, Glaser, Selina, additional, Wagener, Rabea, additional, Ammerpohl, Ole, additional, Bens, Susanne, additional, Giefing, Maciej, additional, Sanchez, Juan C. Gonzalez, additional, Apic, Gordana, additional, Hubschmann, Daniel, additional, Janz, Martin, additional, Kreuz, Markus, additional, Mottok, Anja, additional, Muller, Judith M., additional, Seufert, Julian, additional, Hoffmann, Steve, additional, Korbel, Jan O., additional, Russell, Robert B., additional, Schule, Roland, additional, Trumper, Lorenz, additional, Klapper, Wolfram, additional, Radlwimmer, Bernhard, additional, Lichter, Peter, additional, Kuppers, Ralf, additional, Schlesner, Matthias, additional, Mathas, Stephan, additional, and Siebert, Reiner, additional

Published
2022
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20. T‐cell prolymphocytic leukemia is associated with deregulation of oncogenic microRNAs on transcriptional and epigenetic level

Author

Patil, Paurnima, primary, Hillebrecht, Sina, additional, Chteinberg, Emil, additional, López, Cristina, additional, Toprak, Umut H., additional, Seufert, Julian, additional, Bernhart, Stephan H., additional, Kretzmer, Helene, additional, Bergmann, Anke K., additional, Bens, Susanne, additional, Högel, Josef, additional, Müller, Annika, additional, Jebaraj, Billy Michael, additional, Schrader, Alexandra, additional, Johansson, Patricia, additional, Costa, Dolors, additional, Schlesner, Matthias, additional, Dürig, Jan, additional, Herling, Marco, additional, Campo, Elias, additional, Stilgenbauer, Stephan, additional, Wiehle, Laura, additional, and Siebert, Reiner, additional

Published
2022
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21. Comprehensive genomic analysis of refractory multiple myeloma reveals a complex mutational landscape associated with drug resistance and novel therapeutic vulnerabilities

Author

Giesen, Nicola, primary, Paramasivam, Nagarajan, additional, Toprak, Umut H., additional, Huebschmann, Daniel, additional, Xu, Jing, additional, Uhrig, Sebastian, additional, Samur, Mehmet, additional, Bähr, Stella, additional, Fröhlich, Martina, additional, Mughal, Sadaf S., additional, Mai, Elias K., additional, Jauch, Anna, additional, Müller-Tidow, Carsten, additional, Brors, Benedikt, additional, Munshi, Nikhil, additional, Goldschmidt, Hartmut, additional, Weinhold, Niels, additional, Schlesner, Matthias, additional, and Raab, Marc S., additional

Published
2022
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22. Loss of p16INK4a in neuroblastoma cells induces shift to an immature state with mesenchymal characteristics and increases sensitivity to EGFR inhibitors

Author

Schubert, Nil A., primary, van Hooff, Sander R., additional, Schild, Linda, additional, Ober, Kimberley, additional, Hortensius, Marjolein, additional, van den Handel, Kim, additional, Essing, Anke H.W., additional, Koopmans, Bianca, additional, Boeije, Manon, additional, Proost, Natalie, additional, van de Ven, Marieke, additional, Jansky, Selina, additional, Stainczyk, Sabine A., additional, Toprak, Umut H., additional, Westermann, Frank, additional, Eising, Selma, additional, Molenaar, Jan J., additional, and van den Boogaard, Marlinde L., additional

Published
2021
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23. FOXR2 Stabilizes MYCN Protein and Identifies Non–MYCN-Amplified Neuroblastoma Patients With Unfavorable Outcome

Author

Schmitt-Hoffner, Felix, primary, van Rijn, Sjoerd, additional, Toprak, Umut H., additional, Mauermann, Monika, additional, Rosemann, Felix, additional, Heit-Mondrzyk, Anke, additional, Hübner, Jens-Martin, additional, Camgöz, Aylin, additional, Hartlieb, Sabine, additional, Pfister, Stefan M., additional, Henrich, Kai-Oliver, additional, Westermann, Frank, additional, and Kool, Marcel, additional

Published
2021
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24. Single-cell transcriptomic analyses provide insights into the developmental origins of neuroblastoma

Author

Jansky, Selina, primary, Sharma, Ashwini Kumar, additional, Körber, Verena, additional, Quintero, Andrés, additional, Toprak, Umut H., additional, Wecht, Elisa M., additional, Gartlgruber, Moritz, additional, Greco, Alessandro, additional, Chomsky, Elad, additional, Grünewald, Thomas G. P., additional, Henrich, Kai-Oliver, additional, Tanay, Amos, additional, Herrmann, Carl, additional, Höfer, Thomas, additional, and Westermann, Frank, additional

Published
2021
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25. Kalirin-RAC controls nucleokinetic migration in ADRN-type neuroblastoma

Author

Afanasyeva, Elena A, primary, Gartlgruber, Moritz, additional, Ryl, Tatsiana, additional, Decaesteker, Bieke, additional, Denecker, Geertrui, additional, Mönke, Gregor, additional, Toprak, Umut H, additional, Florez, Andres, additional, Torkov, Alica, additional, Dreidax, Daniel, additional, Herrmann, Carl, additional, Okonechnikov, Konstantin, additional, Ek, Sara, additional, Sharma, Ashwini Kumar, additional, Sagulenko, Vitaliya, additional, Speleman, Frank, additional, Henrich, Kai-Oliver, additional, and Westermann, Frank, additional

Published
2021
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26. Alternative lengthening of telomeres in childhood neuroblastoma from genome to proteome

Author

Hartlieb, Sabine A., primary, Sieverling, Lina, additional, Nadler-Holly, Michal, additional, Ziehm, Matthias, additional, Toprak, Umut H., additional, Herrmann, Carl, additional, Ishaque, Naveed, additional, Okonechnikov, Konstantin, additional, Gartlgruber, Moritz, additional, Park, Young-Gyu, additional, Wecht, Elisa Maria, additional, Savelyeva, Larissa, additional, Henrich, Kai-Oliver, additional, Rosswog, Carolina, additional, Fischer, Matthias, additional, Hero, Barbara, additional, Jones, David T. W., additional, Pfaff, Elke, additional, Witt, Olaf, additional, Pfister, Stefan M., additional, Volckmann, Richard, additional, Koster, Jan, additional, Kiesel, Katharina, additional, Rippe, Karsten, additional, Taschner-Mandl, Sabine, additional, Ambros, Peter, additional, Brors, Benedikt, additional, Selbach, Matthias, additional, Feuerbach, Lars, additional, and Westermann, Frank, additional

Published
2021
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27. Accurate and efficient detection of gene fusions from RNA sequencing data

Author

Uhrig, Sebastian, primary, Ellermann, Julia, additional, Walther, Tatjana, additional, Burkhardt, Pauline, additional, Fröhlich, Martina, additional, Hutter, Barbara, additional, Toprak, Umut H., additional, Neumann, Olaf, additional, Stenzinger, Albrecht, additional, Scholl, Claudia, additional, Fröhling, Stefan, additional, and Brors, Benedikt, additional

Published
2021
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28. Super enhancers define regulatory subtypes and cell identity in neuroblastoma

Author

Gartlgruber, Moritz, primary, Sharma, Ashwini Kumar, additional, Quintero, Andrés, additional, Dreidax, Daniel, additional, Jansky, Selina, additional, Park, Young-Gyu, additional, Kreth, Sina, additional, Meder, Johanna, additional, Doncevic, Daria, additional, Saary, Paul, additional, Toprak, Umut H., additional, Ishaque, Naveed, additional, Afanasyeva, Elena, additional, Wecht, Elisa, additional, Koster, Jan, additional, Versteeg, Rogier, additional, Grünewald, Thomas G. P., additional, Jones, David T. W., additional, Pfister, Stefan M., additional, Henrich, Kai-Oliver, additional, van Nes, Johan, additional, Herrmann, Carl, additional, and Westermann, Frank, additional

Published
2020
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29. Globally altered epigenetic landscape and delayed osteogenic differentiation in H3.3-G34W-mutant giant cell tumor of bone

Author

Lutsik, Pavlo, primary, Baude, Annika, additional, Mancarella, Daniela, additional, Öz, Simin, additional, Kühn, Alexander, additional, Toth, Reka, additional, Hey, Joschka, additional, Toprak, Umut H., additional, Lim, Jinyeong, additional, Nguyen, Viet Ha, additional, Jiang, Chao, additional, Mayakonda, Anand, additional, Hartmann, Mark, additional, Rosemann, Felix, additional, Breuer, Kersten, additional, Vonficht, Dominik, additional, Grünschläger, Florian, additional, Lee, Suman, additional, Schuhmacher, Maren Kirstin, additional, Kusevic, Denis, additional, Jauch, Anna, additional, Weichenhan, Dieter, additional, Zustin, Jozef, additional, Schlesner, Matthias, additional, Haas, Simon, additional, Park, Joo Hyun, additional, Park, Yoon Jung, additional, Oppermann, Udo, additional, Jeltsch, Albert, additional, Haller, Florian, additional, Fellenberg, Jörg, additional, Lindroth, Anders M., additional, and Plass, Christoph, additional

Published
2020
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30. Therapeutic vulnerabilities in the DNA damage response for the treatment of ATRX mutant neuroblastoma

Author

George, Sally L, primary, Lorenzi, Federica, additional, King, David, additional, Hartlieb, Sabine, additional, Campbell, James, additional, Pemberton, Helen, additional, Toprak, Umut H, additional, Barker, Karen, additional, Tall, Jennifer, additional, da Costa, Barbara Martins, additional, van den Boogaard, Marlinde L, additional, Dolman, M Emmy M, additional, Molenaar, Jan J, additional, Bryant, Helen E, additional, Westermann, Frank, additional, Lord, Christopher J, additional, and Chesler, Louis, additional

Published
2020
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31. Globally altered epigenetic landscape and lagging osteogenic differentiation in H3.3-G34W-mutant giant cell tumor of bone

Author

Lutsik, Pavlo, primary, Baude, Annika, additional, Mancarella, Daniela, additional, Oez, Simin, additional, Kuehn, Alexander, additional, Toth, Reka, additional, Hey, Joschka, additional, Toprak, Umut H., additional, Lim, Jinyeong, additional, Nguyen, Viet Ha, additional, Jiang, Chao, additional, Mayakonda, Anand, additional, Hartmann, Mark, additional, Rosemann, Felix, additional, Breuer, Kersten, additional, Vonficht, Dominik, additional, Gruenschlaeger, Florian, additional, Lee, Suman, additional, Schuhmacher, Maren Kirstin, additional, Kusevic, Denis, additional, Jauch, Anna, additional, Weichenhan, Dieter, additional, Zustin, Jozef, additional, Schlesner, Matthias, additional, Haas, Simon, additional, Park, Joo Hyun, additional, Park, Yoon Jung, additional, Oppermann, Udo, additional, Jeltsch, Albert, additional, Haller, Florian, additional, Fellenberg, Joerg, additional, Lindroth, Anders, additional, and Plass, Christoph, additional

Published
2020
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32. Reconstruction of rearranged T‐cell receptor loci by whole genome and transcriptome sequencing gives insights into the initial steps of T‐cell prolymphocytic leukemia

Author

Patil, Paurnima, primary, Cieslak, Agata, additional, Bernhart, Stephan H., additional, Toprak, Umut H., additional, Wagener, Rabea, additional, López, Cristina, additional, Wiehle, Laura, additional, Bens, Susanne, additional, Altmüller, Janine, additional, Franitza, Marek, additional, Scholz, Ingrid, additional, Jayne, Sandrine, additional, Ahearne, Matthew J., additional, Scheffold, Annika, additional, Jebaraj, Billy M. C., additional, Schneider, Christof, additional, Costa, Dolors, additional, Braun, Till, additional, Schrader, Alexandra, additional, Campo, Elias, additional, Dyer, Martin J. S., additional, Nürnberg, Peter, additional, Dürig, Jan, additional, Johansson, Patricia, additional, Böttcher, Sebastian, additional, Schlesner, Matthias, additional, Herling, Marco, additional, Stilgenbauer, Stephan, additional, Macintyre, Elizabeth, additional, and Siebert, Reiner, additional

Published
2019
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33. Cryptic insertion of MYC exons 2 and 3 into the immunoglobulin heavy chain locus detected by whole genome sequencing in a case of “MYC-negative” Burkitt lymphoma

Author

Wagener, Rabea, primary, Bens, Susanne, additional, Toprak, Umut H., additional, Seufert, Julian, additional, López, Cristina, additional, Scholz, Ingrid, additional, Herbrueggen, Heidi, additional, Oschlies, Ilske, additional, Stilgenbauer, Stephan, additional, Schlesner, Matthias, additional, Klapper, Wolfram, additional, Burkhardt, Birgit, additional, and Siebert, Reiner, additional

Published
2019
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34. Mutational patterns and regulatory networks in epigenetic subgroups of meningioma

Author

Paramasivam, Nagarajan, primary, Hübschmann, Daniel, additional, Toprak, Umut H, additional, Ishaque, Naveed, additional, Neidert, Marian, additional, Schrimpf, Daniel, additional, Stichel, Damian, additional, Reuss, David, additional, Sievers, Philipp, additional, Reinhardt, Annekathrin, additional, Wefers, Annika K., additional, Jones, David T. W., additional, Gu, Zuguang, additional, Werner, Johannes, additional, Uhrig, Sebastian, additional, Wirsching, Hans-Georg, additional, Schick, Matthias, additional, Bewerunge-Hudler, Melanie, additional, Beck, Katja, additional, Brehmer, Stephanie, additional, Urbschat, Steffi, additional, Seiz-Rosenhagen, Marcel, additional, Hänggi, Daniel, additional, Herold-Mende, Christel, additional, Ketter, Ralf, additional, Eils, Roland, additional, Ram, Zvi, additional, Pfister, Stefan M., additional, Wick, Wolfgang, additional, Weller, Michael, additional, Grossmann, Rachel, additional, von Deimling, Andreas, additional, Schlesner, Matthias, additional, and Sahm, Felix, additional

Published
2019
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35. IG-MYC+ neoplasms with precursor B-cell phenotype are molecularly distinct from Burkitt lymphomas

Author

Wagener, Rabea, primary, López, Cristina, primary, Kleinheinz, Kortine, primary, Bausinger, Julia, primary, Aukema, Sietse M., primary, Nagel, Inga, primary, Toprak, Umut H., primary, Seufert, Julian, primary, Altmüller, Janine, primary, Thiele, Holger, primary, Schneider, Christof, primary, Kolarova, Julia, primary, Park, Jeongbin, primary, Hübschmann, Daniel, primary, Murga Penas, Eva M., primary, Drexler, Hans G., primary, Attarbaschi, Andishe, primary, Hovland, Randi, primary, Kjeldsen, Eigil, primary, Kneba, Michael, primary, Kontny, Udo, primary, de Leval, Laurence, primary, Nürnberg, Peter, primary, Oschlies, Ilske, primary, Oscier, David, primary, Schlegelberger, Brigitte, primary, Stilgenbauer, Stephan, primary, Wössmann, Wilhelm, primary, Schlesner, Matthias, primary, Burkhardt, Birgit, primary, Klapper, Wolfram, primary, Jaffe, Elaine S., primary, Küppers, Ralf, primary, and Siebert, Reiner, primary

Published
2018
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36. Whole genome sequencing puts forward hypotheses on metastasis evolution and therapy in colorectal cancer

Author

Ishaque, Naveed, primary, Abba, Mohammed L., additional, Hauser, Christine, additional, Patil, Nitin, additional, Paramasivam, Nagarajan, additional, Huebschmann, Daniel, additional, Leupold, Jörg Hendrik, additional, Balasubramanian, Gnana Prakash, additional, Kleinheinz, Kortine, additional, Toprak, Umut H., additional, Hutter, Barbara, additional, Benner, Axel, additional, Shavinskaya, Anna, additional, Zhou, Chan, additional, Gu, Zuguang, additional, Kerssemakers, Jules, additional, Marx, Alexander, additional, Moniuszko, Marcin, additional, Kozlowski, Miroslaw, additional, Reszec, Joanna, additional, Niklinski, Jacek, additional, Eils, Jürgen, additional, Schlesner, Matthias, additional, Eils, Roland, additional, Brors, Benedikt, additional, and Allgayer, Heike, additional

Published
2018
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37. NRG1 Fusions in KRAS Wild-Type Pancreatic Cancer

Author

Heining, Christoph, primary, Horak, Peter, additional, Uhrig, Sebastian, additional, Codo, Paula L., additional, Klink, Barbara, additional, Hutter, Barbara, additional, Fröhlich, Martina, additional, Bonekamp, David, additional, Richter, Daniela, additional, Steiger, Katja, additional, Penzel, Roland, additional, Endris, Volker, additional, Ehrenberg, Karl Roland, additional, Frank, Stephanie, additional, Kleinheinz, Kortine, additional, Toprak, Umut H., additional, Schlesner, Matthias, additional, Mandal, Ranadip, additional, Schulz, Lothar, additional, Lambertz, Helmut, additional, Fetscher, Sebastian, additional, Bitzer, Michael, additional, Malek, Nisar P., additional, Horger, Marius, additional, Giese, Nathalia A., additional, Strobel, Oliver, additional, Hackert, Thilo, additional, Springfeld, Christoph, additional, Feuerbach, Lars, additional, Bergmann, Frank, additional, Schröck, Evelin, additional, von Kalle, Christof, additional, Weichert, Wilko, additional, Scholl, Claudia, additional, Ball, Claudia R., additional, Stenzinger, Albrecht, additional, Brors, Benedikt, additional, Fröhling, Stefan, additional, and Glimm, Hanno, additional

Published
2018
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38. Screening drug effects in patient‐derived cancer cells links organoid responses to genome alterations

Author

Jabs, Julia, primary, Zickgraf, Franziska M, additional, Park, Jeongbin, additional, Wagner, Steve, additional, Jiang, Xiaoqi, additional, Jechow, Katharina, additional, Kleinheinz, Kortine, additional, Toprak, Umut H, additional, Schneider, Marc A, additional, Meister, Michael, additional, Spaich, Saskia, additional, Sütterlin, Marc, additional, Schlesner, Matthias, additional, Trumpp, Andreas, additional, Sprick, Martin, additional, Eils, Roland, additional, and Conrad, Christian, additional

Published
2017
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39. Meningiomas induced by low-dose radiation carry structural variants of NF2 and a distinct mutational signature

Author

Sahm, Felix, primary, Toprak, Umut H., additional, Hübschmann, Daniel, additional, Kleinheinz, Kortine, additional, Buchhalter, Ivo, additional, Sill, Martin, additional, Stichel, Damian, additional, Schick, Matthias, additional, Bewerunge-Hudler, Melanie, additional, Schrimpf, Daniel, additional, Zadeh, Gelareh, additional, Aldape, Ken, additional, Herold-Mende, Christel, additional, Beck, Katja, additional, Staszewski, Ori, additional, Prinz, Marco, additional, Harosh, Carmit Ben, additional, Eils, Roland, additional, Sturm, Dominik, additional, Jones, David T. W., additional, Pfister, Stefan M., additional, Paulus, Werner, additional, Ram, Zvi, additional, Schlesner, Matthias, additional, Grossman, Rachel, additional, and von Deimling, Andreas, additional

Published
2017
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40. Resolving drug effects in patient-derived cancer cells links organoid responses to genome alterations

Author

Neugebauer, Julia, primary, Zickgraf, Franziska M., additional, Park, Jeongbin, additional, Wagner, Steve, additional, Jiang, Xiaoqi, additional, Jechow, Katharina, additional, Kleinheinz, Kortine, additional, Toprak, Umut H., additional, Schneider, Marc A., additional, Meister, Michael, additional, Spaich, Saskia, additional, Sütterlin, Marc, additional, Schlesner, Matthias, additional, Trumpp, Andreas, additional, Sprick, Martin, additional, Eils, Roland, additional, and Conrad, Christian, additional

Published
2017
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42. New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs

Author

Sturm, Dominik, primary, Orr, Brent A., additional, Toprak, Umut H., additional, Hovestadt, Volker, additional, Jones, David T.W., additional, Capper, David, additional, Sill, Martin, additional, Buchhalter, Ivo, additional, Northcott, Paul A., additional, Leis, Irina, additional, Ryzhova, Marina, additional, Koelsche, Christian, additional, Pfaff, Elke, additional, Allen, Sariah J., additional, Balasubramanian, Gnanaprakash, additional, Worst, Barbara C., additional, Pajtler, Kristian W., additional, Brabetz, Sebastian, additional, Johann, Pascal D., additional, Sahm, Felix, additional, Reimand, Jüri, additional, Mackay, Alan, additional, Carvalho, Diana M., additional, Remke, Marc, additional, Phillips, Joanna J., additional, Perry, Arie, additional, Cowdrey, Cynthia, additional, Drissi, Rachid, additional, Fouladi, Maryam, additional, Giangaspero, Felice, additional, Łastowska, Maria, additional, Grajkowska, Wiesława, additional, Scheurlen, Wolfram, additional, Pietsch, Torsten, additional, Hagel, Christian, additional, Gojo, Johannes, additional, Lötsch, Daniela, additional, Berger, Walter, additional, Slavc, Irene, additional, Haberler, Christine, additional, Jouvet, Anne, additional, Holm, Stefan, additional, Hofer, Silvia, additional, Prinz, Marco, additional, Keohane, Catherine, additional, Fried, Iris, additional, Mawrin, Christian, additional, Scheie, David, additional, Mobley, Bret C., additional, Schniederjan, Matthew J., additional, Santi, Mariarita, additional, Buccoliero, Anna M., additional, Dahiya, Sonika, additional, Kramm, Christof M., additional, von Bueren, André O., additional, von Hoff, Katja, additional, Rutkowski, Stefan, additional, Herold-Mende, Christel, additional, Frühwald, Michael C., additional, Milde, Till, additional, Hasselblatt, Martin, additional, Wesseling, Pieter, additional, Rößler, Jochen, additional, Schüller, Ulrich, additional, Ebinger, Martin, additional, Schittenhelm, Jens, additional, Frank, Stephan, additional, Grobholz, Rainer, additional, Vajtai, Istvan, additional, Hans, Volkmar, additional, Schneppenheim, Reinhard, additional, Zitterbart, Karel, additional, Collins, V. Peter, additional, Aronica, Eleonora, additional, Varlet, Pascale, additional, Puget, Stephanie, additional, Dufour, Christelle, additional, Grill, Jacques, additional, Figarella-Branger, Dominique, additional, Wolter, Marietta, additional, Schuhmann, Martin U., additional, Shalaby, Tarek, additional, Grotzer, Michael, additional, van Meter, Timothy, additional, Monoranu, Camelia-Maria, additional, Felsberg, Jörg, additional, Reifenberger, Guido, additional, Snuderl, Matija, additional, Forrester, Lynn Ann, additional, Koster, Jan, additional, Versteeg, Rogier, additional, Volckmann, Richard, additional, van Sluis, Peter, additional, Wolf, Stephan, additional, Mikkelsen, Tom, additional, Gajjar, Amar, additional, Aldape, Kenneth, additional, Moore, Andrew S., additional, Taylor, Michael D., additional, Jones, Chris, additional, Jabado, Nada, additional, Karajannis, Matthias A., additional, Eils, Roland, additional, Schlesner, Matthias, additional, Lichter, Peter, additional, von Deimling, Andreas, additional, Pfister, Stefan M., additional, Ellison, David W., additional, Korshunov, Andrey, additional, and Kool, Marcel, additional

Published
2016
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44. Modulation of the Chromatin Phosphoproteome by the Haspin Protein Kinase

Author

Maiolica, Alessio, primary, de Medina-Redondo, Maria, additional, Schoof, Erwin M., additional, Chaikuad, Apirat, additional, Villa, Fabrizio, additional, Gatti, Marco, additional, Jeganathan, Siva, additional, Lou, Hua Jane, additional, Novy, Karel, additional, Hauri, Simon, additional, Toprak, Umut H., additional, Herzog, Franz, additional, Meraldi, Patrick, additional, Penengo, Lorenza, additional, Turk, Benjamin E., additional, Knapp, Stefan, additional, Linding, Rune, additional, and Aebersold, Ruedi, additional

Published
2014
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